{"id":20807,"date":"2022-04-14T08:01:48","date_gmt":"2022-04-14T08:01:48","guid":{"rendered":"https:\/\/zeepedia.com\/?p=20807"},"modified":"2022-04-15T15:25:54","modified_gmt":"2022-04-15T15:25:54","slug":"phesgo","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/phesgo\/","title":{"rendered":"Phesgo &#8211; Pertuzumab \/ Trastuzumab uses, dose and side effects"},"content":{"rendered":"\n<p>Physio 600 mg \/ 600 mg solution for injection Phesgo 1200 mg \/ 600 mg solution for injection<br>pertuzumab \/ <a href=\"https:\/\/zeepedia.com\/medical\/medicines\/trazimera\/\">trastuzumab<\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Physio is and what it is used for<\/h2>\n\n\n\n<p>Physio is a cancer drug that contains two active substances: pertuzumab and trastuzumab.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Pertuzumab and trastuzumab are monoclonal\u00a0antibodies.\u00a0They are designed to attach to a specific site on the cells, called &#8220;human\u00a0epidermal\u00a0growth factor receptor 2&#8221; (\u00a0HER2\u00a0).<\/li><li>HER2\u00a0is found in large amounts on the surface of certain cancer cells and stimulates cell growth.<\/li><li>By attaching\u00a0HER2\u00a0to the cancer cells, pertuzumab and trastuzumab can slow or kill their growth.<\/li><\/ul>\n\n\n\n<p>Physio is available in two different strengths.\u00a0See section 6 for further information.<\/p>\n\n\n\n<p>Physio is used to treat adult patients with\u00a0HER2\u00a0-positive breast cancer &#8211; your doctor will examine you for this.\u00a0The drug can be used then:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>cancer has spread to other parts of the body such as the lungs and liver (metastasized) or cancer has returned to the breast and the area around the breast but cannot be operated on<\/li><li>and no treatment with cancer drugs (\u00a0chemotherapy\u00a0) or other drugs designed to attach to\u00a0HER2\u00a0has been given.<\/li><li>cancer has not spread to other parts of the body and treatment should be given either before\u00a0surgery\u00a0(\u00a0neoadjuvant\u00a0treatment) or after\u00a0surgery\u00a0(\u00a0adjuvant\u00a0treatment).<\/li><\/ul>\n\n\n\n<p>As part of your treatment with Phesgo, you will also receive other medicines called\u00a0chemotherapy.\u00a0Information on these medicines can be found in separate package leaflets.\u00a0Ask your doctor, pharmacist, or nurse for information about these other medicines.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What You Need to Know Before You Get Phesgo<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">You should not get Phesgo:<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to pertuzumab, trastuzumab, or any of the other ingredients of this medicine (listed in section 6).<\/li><\/ul>\n\n\n\n<p>If you are not sure, talk to your doctor, pharmacist, or nurse before taking Phesgo.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Heart problems<\/p>\n\n\n\n<p>Treatment with Phesgo can affect the heart.&nbsp;Talk to your doctor or nurse before receiving Phesgo about:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>you have previously had heart problems (such as\u00a0heart failure, treatment for severe irregular heartbeat, uncontrolled high\u00a0blood pressure, recent myocardial infarction).\u00a0Your doctor will check that your heart is functioning properly before and during treatment with Phesgo.<\/li><li>you have had heart problems with previous treatment with any medicine that contains trastuzumab.<\/li><li>you have previously been treated with\u00a0chemotherapy\u00a0from a group of cancer medicines called\u00a0anthracyclines, such as doxorubicin or epirubicin &#8211; these medicines can damage the heart muscle and increase the risk of heart problems when treated with Phesgo.<\/li><li>you have previously received radiation to the chest area, as it may increase the risk of heart problems.<\/li><\/ul>\n\n\n\n<p>If any of the above apply to you (or you are not sure), talk to your doctor or nurse before taking Phesgo.&nbsp;See section 4 \u201cSerious side effects\u201d for more information on signs of heart problems.<\/p>\n\n\n\n<p>Injection reactions<\/p>\n\n\n\n<p>Injection reactions may occur.&nbsp;They are allergic reactions and can be serious.<\/p>\n\n\n\n<p>If you get a severe reaction, your doctor may stop taking Phesgo.\u00a0See section 4 \u201cSerious side effects\u201d for more information on injection reactions that may occur during\u00a0or after\u00a0injection.<\/p>\n\n\n\n<p>Your doctor or nurse will observe you and check if you get any&nbsp;side effects&nbsp;during the&nbsp;injection&nbsp;and:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>for another 30 minutes after the first&nbsp;injection&nbsp;one with Phesgo.<\/li><li>for a further 15 minutes after the subsequent&nbsp;injections&nbsp;of Phesgo.&nbsp;<\/li><\/ul>\n\n\n\n<p>If you get a severe reaction, your doctor may stop taking Phesgo.<\/p>\n\n\n\n<p>Low&nbsp;white blood cell count&nbsp;and fever (Febrile&nbsp;neutropenia&nbsp;)<\/p>\n\n\n\n<p>When Phesgo is given chemotherapy, the number of\u00a0white blood cells\u00a0may decrease and fever may occur.\u00a0If you have any\u00a0inflammation\u00a0in the digestive tract (eg sores in the mouth or diarrhea), you may be more likely to get this\u00a0side effect.\u00a0If the fever persists for several days, it may be a sign of worsening your condition and you should contact your doctor.<\/p>\n\n\n\n<p>Diarrhea<\/p>\n\n\n\n<p>Treatment with Phesgo can cause severe diarrhea.&nbsp;Patients over the age of 65 have a higher risk of developing diarrhea, compared with patients under the age of 65.&nbsp;If you experience severe diarrhea during your cancer treatment, your doctor may prescribe you medicines for diarrhea.&nbsp;Your doctor may also stop your treatment with Phesgo until the diarrhea is under control.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children and young people<\/h2>\n\n\n\n<p>Pesto should not be used in patients under 18 years of age, as there is no information on the treatment for this age group.<\/p>\n\n\n\n<p><strong>Elderly patients over 65 years<\/strong><\/p>\n\n\n\n<p>Patients over the age of 65 are more likely to experience\u00a0side effects\u00a0such as decreased appetite, decreased\u00a0red blood cell count, weight loss, fatigue, lost or altered taste, weakness, numbness, stinging or tingling sensation (mainly in the feet and legs) and diarrhea, compared to younger patients. than 65 years.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other drugs and Phesgo<\/h2>\n\n\n\n<p>Tell your doctor, pharmacist, or nurse if you are taking, have recently taken, or might take any other medicines.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, breastfeeding, and fertility<\/h2>\n\n\n\n<p>Before starting treatment, you must tell your doctor, pharmacist, or nurse if you are pregnant or breastfeeding, or if you think you may be pregnant or are planning to have a baby.<\/p>\n\n\n\n<p>Your doctor will talk to you about the benefits and disadvantages, for you and your baby, of taking Phesgo during pregnancy.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Tell your doctor immediately if you become pregnant during treatment with Phesgo or for 7 months after stopping treatment.\u00a0Phesgo can harm the unborn baby.\u00a0You should use effective contraception during treatment with Phesgo and for 7 months after stopping treatment.<\/li><li>Discuss with your doctor if you can breastfeed during or after treatment with Phesgo.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Phesgo may affect your ability to drive or use machines.\u00a0If you get symptoms such as dizziness, chills, fever, or any injection reaction or\u00a0allergic reaction\u00a0(as described in section 4), do not drive or use machines until these symptoms have disappeared.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Phesgo contains sodium<\/h2>\n\n\n\n<p>Phesgo contains less than 1 mmol\u00a0sodium\u00a0(23 mg) per\u00a0dose, ie essentially &#8216;sodium-free&#8217;.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to get Phesgo<\/h2>\n\n\n\n<p>Phesgo will be given to you by a doctor or nurse at a hospital or clinic.&nbsp;Phesgo is given as an&nbsp;injection&nbsp;under the skin (&nbsp;subcutaneous&nbsp;injection&nbsp;).<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>The injection\u00a0will be given every three weeks.<\/li><li>You will receive an\u00a0injection\u00a0first in one thigh than in the other.\u00a0You will continue to receive the\u00a0injections\u00a0alternately between one and the other thigh.<\/li><li>Your doctor or nurse will make sure that each\u00a0injection\u00a0is given at a new site (at least 2.5 cm from a previous injection site) and where the skin is not red, bruised, tender, or hard.<\/li><li>Other injection sites should be used for other drugs.<\/li><\/ul>\n\n\n\n<p><strong>Start of treatment (&nbsp;loading dose&nbsp;)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Phesgo 1200 mg \/ 600 mg will be given under your skin for 8 minutes.\u00a0Your doctor or nurse will check if you get\u00a0any side effects\u00a0during the\u00a0injection\u00a0and for 30 minutes afterward.<\/li><li>You will also receive\u00a0chemotherapy.<\/li><\/ul>\n\n\n\n<p><strong>Subsequent&nbsp;injections&nbsp;(maintenance doses),<\/strong>&nbsp;which will be given if the first&nbsp;injection&nbsp;did not cause any serious side effects:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Phesgo 600 mg \/ 600 mg will be given under your skin for 5 minutes.\u00a0Your doctor or nurse will check if you get\u00a0any side effects\u00a0during the\u00a0injection\u00a0and for 15 minutes afterward.<\/li><li>You will also receive\u00a0chemotherapy\u00a0depending on your doctor&#8217;s\u00a0prescription.<\/li><li>The number of\u00a0injections\u00a0you will receive depends on:<ul><li>how to respond to treatment<\/li><li>if you are receiving treatment before or after\u00a0surgery\u00a0or if the disease has spread.<\/li><\/ul><\/li><\/ul>\n\n\n\n<p>For further information on&nbsp;charge dose&nbsp;and maintenance dose, see section 6.<\/p>\n\n\n\n<p>For more information on\u00a0chemotherapy\u00a0dosage\u00a0(\u00a0which may also cause\u00a0side effects\u00a0), read the package leaflet for these medicines.\u00a0If you have any further questions, ask your doctor, pharmacist, or nurse.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to use Phesgo<\/h2>\n\n\n\n<p>If you miss your booked time to get Phesgo, a new appointment should be booked as soon as possible.&nbsp;Depending on the length of time between two visits, your doctor will decide which strength of Phesgo to give you.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop using Phesgo<\/h2>\n\n\n\n<p>Do not stop your treatment with this medicine without talking to your doctor first.\u00a0You must get all your\u00a0injections\u00a0in the treatment regimen at the right time every three weeks.\u00a0This helps the drug to work as well as possible.<\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor, pharmacist, or nurse.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p><strong>Serious&nbsp;side effects&nbsp;are<\/strong><\/p>\n\n\n\n<p><strong>Tell your doctor or nurse immediately if you notice any of the following side effects:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Heart problems:<\/strong>\u00a0slower or faster heartbeat than usual, or\u00a0heart palpitations\u00a0and symptoms such as cough, shortness of breath, and swelling (fluid accumulation) in the arms or legs.<\/li><li>Injection-related reactions:\u00a0may be mild or more severe and may include nausea, fever, chills, fatigue, headache, loss of appetite, joint, and muscle aches, and hot flashes.<\/li><li>Diarrhea:\u00a0may be mild or moderate, but may also be very severe (watery stools 7 or more times a day) or persistent.<\/li><li>Decreased\u00a0white blood cell count\u00a0(\u00a0detected by a blood test): may occur with or without fever.<\/li><li>Allergic reactions: swelling of the face and throat\/airways, difficulty breathing;\u00a0maybe a sign of a severe\u00a0allergic reaction.<\/li><li>Tumor light syndrome\u00a0(a condition that can occur when cancer cells die quickly).\u00a0Symptoms may include:<ul><li>kidney problems (signs include weakness, shortness of breath, fatigue, and confusion)<\/li><li>heart problems (signs include palpitations with a faster or slower heartbeat)<\/li><li>cramps, vomiting, or diarrhea as well as tingling in the mouth, hands, or feet.<\/li><\/ul><\/li><\/ul>\n\n\n\n<p>Tell your doctor or nurse immediately if you notice any of the above\u00a0side effects.<\/p>\n\n\n\n<p><strong>Other&nbsp;side effects&nbsp;ar<\/strong><\/p>\n\n\n\n<p><strong>Very common (more than 1 in 10 patients):<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Hair loss<\/li><li>Rash<\/li><li>Inflammation\u00a0of the digestive tract (eg sore mouth)<\/li><li>Reduced number of\u00a0red blood cells\u00a0(detected by a blood test)<\/li><li>Muscle weakness<\/li><li>Constipation<\/li><li>Altered or loss of taste<\/li><li>Insomnia<\/li><li>Feeling of weakness, numbness, tingling, or stinging sensation, especially in the feet and legs<\/li><li>Nasal blood<\/li><li>Heartburn<\/li><li>Dry, itchy, or acne-like skin<\/li><li>Injection site pain, reddening of the skin, and bruising at the injection site<\/li><li>Nail problems, such as discoloration similar to white or dark streaks or altered nail color<\/li><li>Sore throat, red, sore or runny nose,\u00a0flu-like symptoms,\u00a0and fever, which can lead to\u00a0infection\u00a0in the ears, nose, or throat<\/li><li>Increased tear production<\/li><li>Pain in the body, arms, legs, and abdomen<\/li><\/ul>\n\n\n\n<p><strong>Common&nbsp;side effects&nbsp;(up to 1 in 10 patients)<\/strong>&nbsp;:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>The feeling of numbness, tingling, or tingling in the hands<\/li><li>Sharp stabbing, throbbing, icy, or burning pain<\/li><li>Feelings of pain for something that should not be painful, such as light touch<\/li><li>Decreased ability to feel temperature changes<\/li><li>Impaired balance or coordination<\/li><li>Inflammation\u00a0of the\u00a0nail bed\u00a0where the nail and skin meet<\/li><li>Conditions where the left part of the heart does not work properly, with or without symptoms<\/li><\/ul>\n\n\n\n<p><strong>Uncommon (up to 1 in 100 patients)<\/strong>&nbsp;:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Chest symptoms such as dry cough or shortness of breath (possible symptoms of interstitial lung disease, a condition with tissue damage around the air sacs in the lungs)<\/li><li>Fluid around the lungs that causes difficulty breathing<\/li><\/ul>\n\n\n\n<p>If you get any of the\u00a0side effects\u00a0listed above, talk to your doctor, nurse, or pharmacist.<\/p>\n\n\n\n<p>If you get any of the above symptoms after stopping treatment with Phesgo, contact your doctor immediately.&nbsp;Tell them you&#8217;ve been treated to Phesgo before.<\/p>\n\n\n\n<p>Some of the\u00a0side effects\u00a0may be due to your breast cancer.\u00a0If you are receiving Phesgo at the same time as\u00a0chemotherapy, some of the\u00a0side effects\u00a0may be caused by the other medicines.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Phesgo<\/h2>\n\n\n\n<p>Phesgo will be stored by healthcare professionals at the hospital or clinic.&nbsp;The medicinal product must be stored as follows:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Keep this medicine out of the sight and reach of children.<\/li><li>Do not use this medicine after the expiry date which is stated on the carton after EXP.\u00a0data and on the vial after EXP.\u00a0The expiration date is the last day of the specified month.<\/li><li>Store in a refrigerator (2 \u00b0 C &#8211; 8 \u00b0 C).<\/li><li>Do not freeze.<\/li><li>Keep the vial in the outer carton.\u00a0Sensitive to light.<\/li><li>When the vial is opened, the solution should be used immediately.\u00a0The drug should not be used if the solution contains visible particles or if the color is incorrect (see section 6).<\/li><li>Medicines should not be disposed of via wastewater or household waste.\u00a0Ask your pharmacist how to dispose of medicines no longer required.\u00a0These measures will help to protect the environment.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the package and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">What Phesgo contains<\/h2>\n\n\n\n<p>The active substances are pertuzumab and trastuzumab.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Maintenance dose:<\/strong>&nbsp;One&nbsp;vial&nbsp;of 10 ml solution contains 600 mg pertuzumab and 600 mg trastuzumab.&nbsp;Each ml contains 60 mg pertuzumab and 60 mg trastuzumab.<\/li><li><strong>Charge dose:<\/strong>&nbsp;&nbsp;One 15 ml solution&nbsp;for injection&nbsp;contains 1200 mg pertuzumab and 600 mg trastuzumab.&nbsp;Each ml contains 80 mg of pertuzumab and 40 mg of trastuzumab.<\/li><\/ul>\n\n\n\n<p>The other ingredients are hyaluronidase alfa, L-histidine, L \u2011 histidine hydrochloride monohydrate, \u03b1, \u03b1-trehalose dihydrate, sucrose, L-methionine, polysorbate 20, and water for injections (see section 2 \u201cPhesgo contains sodium\u201d).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Phesgo appearance and pack size<\/h2>\n\n\n\n<p>Phesgo is a solution for\u00a0injection.\u00a0It is clear to slightly opalescent, colorless to the slightly brown solution provided in glass vials.\u00a0Each pack contains a\u00a0vial\u00a0of either 10 ml or 15 ml solution.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorisation Holder<\/h2>\n\n\n\n<p>Roche Registration GmbH<\/p>\n\n\n\n<p>Emil-Barell-Strasse 1<\/p>\n\n\n\n<p>79639 Grenzach-Wyhlen<\/p>\n\n\n\n<p>Germany<\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>Roche Pharma AG<\/p>\n\n\n\n<p>Emil-Barell-Strasse 1<\/p>\n\n\n\n<p>79639 Grenzach-Wyhlen<\/p>\n\n\n\n<p>Germany<\/p>\n\n\n\n<p>Contact the representative of the marketing authorization holder to find out more about this medicine:<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td><strong>Belgium \/ Belgique \/ Belgien<\/strong>NV Roche SATel: +32 (0) 2 525 82 11<\/td><td><strong>Lithuania<\/strong>UAB \u201cRoche Lietuva\u201dTel: +370 5 2546799<\/td><\/tr><tr><td><strong>Bulgaria<\/strong>Russia BULGARIA LOODTel: +359 2 818 44 44<\/td><td><strong>Luxembourg \/ Luxemburg<\/strong>(See \/ See Belgium \/ Belgium)<\/td><\/tr><tr><td><strong>Czech Republic<\/strong>Roche sroTel: +420 &#8211; 2 20382111<\/td><td><strong>Hungary<\/strong>Roche (Magyarorsz\u00e1g) Kft.Tel: +36 &#8211; 1 279 4500<\/td><\/tr><tr><td><strong>Denmark<\/strong>Roche a \/ sTel: +45 &#8211; 36 39 99 99<\/td><td><strong>Malta<\/strong>(See United Kingdom)<\/td><\/tr><tr><td><strong>Germany<\/strong>Roche Pharma AGTel: +49 (0) 7624 140<\/td><td><strong>The Netherlands<\/strong>Roche Nederland BVTel: +31 (0) 348 438050<\/td><\/tr><tr><td><strong>Eesti<\/strong>Roche Eesti O\u00dcTel: + 372 &#8211; 6 177 380<\/td><td><strong>Norway<\/strong>Roche Norge ASTel: +47 &#8211; 22 78 90 00<\/td><\/tr><tr><td><strong>Greece<\/strong>Roche (Hellas) AE:\u0397\u03bb: +30 210 61 66 100<\/td><td><strong>Austria<\/strong>Roche Austria GmbHTel: +43 (0) 1 27739<\/td><\/tr><tr><td><strong>Spain<\/strong>Roche Farma SATel: +34 &#8211; 91 324 81 00<\/td><td><strong>Poland<\/strong>Roche Polska Sp.z ooTel: +48 &#8211; 22 345 18 88<\/td><\/tr><tr><td><strong>France<\/strong>RocheTel: +33 (0) 1 47 61 40 00<\/td><td><strong>Portugal<\/strong>Roche Pharmac\u00eautica Chemica, LdaTel: +351 &#8211; 21 425 70 00<\/td><\/tr><tr><td><strong>Croatia<\/strong>Roche dooTel: + 385 1 47 22 333<\/td><td><strong>Romania<\/strong>Roche Rom\u00e2nia SRLTel: +40 21 206 47 01<\/td><\/tr><tr><td><strong>Ireland<\/strong>Roche Products (Ireland) Ltd.Tel: +353 (0) 1 469 0700<\/td><td><strong>Slovenia<\/strong>Roche pharmacevtska dru\u017eba dooTel: +386 &#8211; 1 360 26 00<\/td><\/tr><tr><td><strong>Iceland<\/strong>Roche a \/ sc \/ o Icepharma hfPhone: +354 540 8000<\/td><td><strong>Slovak Republic<\/strong>Roche Slovensko, sroTel: +421 &#8211; 2 52638201<\/td><\/tr><tr><td><strong>Italy<\/strong>Roche SpATel: +39 &#8211; 039 2471<\/td><td><strong>Finland \/ Finland<\/strong>Roche OyPuh \/ Tel: +358 (0) 10 554 500<\/td><\/tr><tr><td><strong>\u038e\u03c0\u03c1\u03bf\u03c2<\/strong>\u0393.\u0391.\u03a3\u03c4\u03b1\u03bc\u03ac\u03c4\u03b7\u03c2 &amp; \u03a3\u03b9\u03b1 \u039b\u03c4\u03b4.:\u0397\u03bb: +357 &#8211; 22 76 62 76<\/td><td><strong>Sweden<\/strong>Roche ABTel: +46 (0) 8 726 1200<\/td><\/tr><tr><td><strong>Latvia<\/strong>Roche Latvija SIATel: +371 &#8211; 6 7039831<\/td><td><strong>United Kingdom (Northern Ireland)<\/strong>Roche Products (Ireland) Ltd.Tel: +44 (0) 1707 366000<\/td><\/tr><\/tbody><\/table><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>Phesgo is a cancer drug that contains two active substances: pertuzumab and trastuzumab.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,18527],"tags":[21180,21300,21176,21179,21296,21299,13800,21297,13801,21178,21298,13802],"class_list":["post-20807","post","type-post","status-publish","format-standard","hentry","category-medicines","category-p","tag-benefits-of-pertuzumab","tag-benefits-of-phesgo","tag-pertuzumab","tag-pertuzumab-side-effects","tag-phesgo","tag-phesgo-side-effects","tag-trastuzumab","tag-what-is-phesgo","tag-what-is-trastuzumab","tag-what-pertuzumab-is-used-for","tag-what-phesgo-is-used-for","tag-what-trastuzumab-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/20807","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=20807"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/20807\/revisions"}],"predecessor-version":[{"id":20865,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/20807\/revisions\/20865"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=20807"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=20807"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=20807"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}