300 mg\u00a0powder for injection \/ infusion \/ nebulizer solution,
pentamine diisethionate solution <\/p>\n\n\n\n
Pentacarinate is a remedy for\u00a0protozoa\u00a0(unicellular\u00a0organisms\u00a0) and is used prophylactically in the treatment of\u00a0pneumonia\u00a0caused by\u00a0Pneumocystis carinii<\/em>\u00a0(PCP) and in the treatment of sleeping sickness.<\/p>\n\n\n\n – if you are allergic (hypersensitive) to pentamidine.<\/p>\n\n\n\n Talk to your doctor or nurse before taking Pentacarinate:<\/p>\n\n\n\n – if you have impaired liver or kidney function<\/p>\n\n\n\n – if you have too high or too low blood pressure<\/p>\n\n\n\n – if you have an abnormally high or low blood sugar level<\/p>\n\n\n\n – if you have low blood pressure<\/p>\n\n\n\n During inhalation therapy, Pentacarinate should be used with caution in people with asthma and when there is a risk of air or gas accumulating in the alveoli (pneumothorax).<\/p>\n\n\n\n Tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.\u00a0Pentacarinate in combination with phenothiazines (for mental disorders),\u00a0tricyclic antidepressants\u00a0(for depression), terfenadine, astemizole (for\u00a0allergies\u00a0), erythromycin (\u00a0antibiotics\u00a0), halofantrine (for\u00a0malaria\u00a0), and\u00a0quinolones\u00a0(\u00a0antibiotics\u00a0) may increase the risk of heart rate.\u00a0Foscarnet (antiviral agent) can lead to decreased calcium levels.<\/p>\n\n\n\n If you are pregnant, breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<\/p>\n\n\n\n Pregnancy:<\/em> It is unclear whether Pentacarinate affects fetal development and the medicine should not be used during pregnancy unless directed to do so by a doctor.<\/p>\n\n\n\n Breast-feeding:<\/em>\u00a0It is unknown whether Pentacarinate passes into breast milk and the medicine should not be used during breastfeeding unless\u00a0prescribed\u00a0by a doctor.<\/p>\n\n\n\n Dizziness has been reported with the use of Pentacarinate.\u00a0You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened vigilance.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects.\u00a0Descriptions of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n Always use Pentacarinate exactly as your doctor has told you. Ask your doctor or pharmacist if you are unsure. Dose one is determined by the doctor, who adjusts it individually for you.<\/p>\n\n\n\n The recommended\u00a0dose\u00a0for:<\/em><\/p>\n\n\n\n Treatment<\/strong>\u00a0of pneumonia:<\/em>\u00a04 mg\/kg body weight once daily for 14-21 days as an\u00a0intravenous\u00a0infusion.<\/p>\n\n\n\n Prevention<\/strong> of pneumonia:<\/em> 300 mg is inhaled once a month or 150 mg every fortnight.<\/p>\n\n\n\n Treatment of sleeping sickness:<\/em>\u00a04 mg\/kg body weight once daily or every other day up to a total of 7-10 doses as an\u00a0intravenous\u00a0infusion.<\/p>\n\n\n\n If you take more Pentacarinat than you should<\/strong><\/p>\n\n\n\n If you have ingested too much medicine or if, for example, a child has accidentally ingested the medicine, contact a doctor or hospital for risk assessment and advice.<\/p>\n\n\n\n If you forget to take Pentacarinate<\/strong><\/p>\n\n\n\n Do not take a double\u00a0dose\u00a0to make up for a forgotten\u00a0dose.<\/p>\n\n\n\n If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n Injection treatment<\/strong><\/em><\/p>\n\n\n\n Up to 50% of patients experience serious\u00a0side effects\u00a0during treatment, such as low\u00a0blood pressure, low blood sugar, and effects on kidney function.<\/p>\n\n\n\n Contact a doctor immediately if you get any of the following symptoms:<\/strong><\/p>\n\n\n\n Other side effects include:<\/em><\/p>\n\n\n\n Very common (affects more than 1 patient in 10):<\/em><\/p>\n\n\n\n Increased nitrogen content in the blood.\u00a0Acute\u00a0renal failure.\u00a0Blood in the urine.\u00a0Local reactions at the injection site such as pain and discomfort.\u00a0Acne, calluses, and muscle necrosis at the injection site.<\/p>\n\n\n\n Common (affects more than 1 patient in 100):<\/em><\/p>\n\n\n\n Decreased\u00a0white blood cell count.\u00a0Bruising or bleeding in the skin due to decreased\u00a0platelet count.\u00a0Anemia.\u00a0Low blood sugar.\u00a0High blood sugar content.\u00a0Increased potassium content in the blood.\u00a0Decreased\u00a0calcium\u00a0and magnesium content in the blood.\u00a0Dizziness, fainting.\u00a0Low\u00a0blood pressure.\u00a0Hot flashing.\u00a0Cough.\u00a0Cramps in the muscles of the trachea, are often associated with increased mucus secretion and thus difficulty breathing.\u00a0Nausea, vomiting, taste change.\u00a0Abnormal liver function tests.\u00a0Skin rash,\u00a0redness,\u00a0itching\u00a0.\u00a0Kidney impact.\u00a0Feeling of pressure behind the sternum.<\/p>\n\n\n\n Rare (affects less than 1 in 1,000 people):<\/em><\/p>\n\n\n\n Allergic reaction\u00a0with fever, rash, local fluid swelling, and drop in blood pressure (anaphylactic\u00a0shock\u00a0).\u00a0Diabetes mellitus\u00a0(may debut several months after treatment).\u00a0Influence on the rhythm of the heart.\u00a0Inflammation\u00a0of the pancreas.<\/p>\n\n\n\n Has been reported (occurs in an unknown number of users):<\/em><\/p>\n\n\n\n Influence on the rhythm of the heart (\u00a0Torsade de Pointes\u00a0).\u00a0Hypersensitivity reactions\u00a0include anaphylactic reactions (\u00a0acute\u00a0and severe\u00a0allergic reactions).\u00a0Slow heartbeat (\u00a0bradycardia\u00a0).<\/p>\n\n\n\n Applies to intravenous treatment only:<\/em><\/p>\n\n\n\n Tingling and numbness in the arms and legs as well as reduced sensitivity to touch around the mouth have been reported in both children and adults.\u00a0The symptoms occurred during\u00a0infusion\u00a0or shortly after the start of the infusion but ceased after discontinuation or discontinuation of\u00a0administration.<\/p>\n\n\n\n Side effects\u00a0that occur with injection therapy can in rare cases occur with\u00a0inhalation.<\/p>\n\n\n\n Inhalation treatment<\/strong><\/em><\/p>\n\n\n\n 2-5% of patients discontinue\u00a0inhalation\u00a0due to\u00a0side effects, usually due to nausea or cough\/spasm of the trachea.<\/p>\n\n\n\n Contact a doctor immediately if you get any of the following symptoms:<\/strong><\/p>\n\n\n\n Swelling of the face, tongue, or throat;\u00a0difficulty swallowing;\u00a0hives\u00a0and difficulty breathing (\u00a0angioedema\u00a0).\u00a0This side effect has been reported (affects an unknown number of users)<\/p>\n\n\n\n Other side effects include:<\/strong><\/em><\/p>\n\n\n\n Common (affects more than 1 patient in 100):<\/em><\/p>\n\n\n\n Nausea, taste change, cough, shortness of breath, convulsions in the trachea, wheezing or wheezing from the airways (especially in smokers and asthmatics). Preventive inhalation of certain drugs can counteract these ailments.<\/p>\n\n\n\n Rare (affects less than 1 in 1,000 people):<\/em><\/p>\n\n\n\n Allergic reaction\u00a0with fever, rash, local fluid swelling, and drop in blood pressure (anaphylactic\u00a0shock\u00a0).\u00a0Allergic\u00a0pneumonia.<\/p>\n\n\n\n Has been reported (occurs in an unknown number of users):<\/em><\/p>\n\n\n\n Low blood sugar.\u00a0Feeling drunk.\u00a0Low\u00a0blood pressure.\u00a0Accumulation of air or gas in the alveoli can cause chest pain and difficulty breathing.\u00a0Inflammation\u00a0of the pancreas (\u00a0acute\u00a0).\u00a0Rash.\u00a0Kidney failure.\u00a0Fever.\u00a0Decreased appetite.\u00a0Fatigue.\u00a0Hypersensitivity reactions\u00a0include anaphylactic reactions (\u00a0acute\u00a0and severe\u00a0allergic reactions).\u00a0Slow heartbeat (\u00a0bradycardia\u00a0).<\/p>\n\n\n\n Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n Do not use this medicine after the expiry date which is stated on the label. The expiration date is the last day of the specified month.<\/p>\n\n\n\n Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.<\/p>\n\n\n\n Content declaration<\/strong><\/p>\n\n\n\n The active substance is pentamidine diisethionate. One vial contains 300 mg of pentamidine diisethionate.<\/p>\n\n\n\n What the medicine looks like and the contents of the pack<\/strong><\/p>\n\n\n\n One pack contains 5 vials.<\/p>\n","protected":false},"excerpt":{"rendered":" Pentacarinate is a remedy for protozoa (unicellular organisms ) and is used prophylactically and in the treatment of pneumonia caused by Pneumocystis carinii (PCP) and in the treatment of sleeping sickness.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,18527],"tags":[21083,21079,21082,21080,21081],"class_list":["post-20691","post","type-post","status-publish","format-standard","hentry","category-medicines","category-p","tag-benefits-of-pentacarinate","tag-pentacarinate","tag-pentacarinate-side-effects","tag-what-is-pentacarinate","tag-what-pentacarinate-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/20691","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=20691"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/20691\/revisions"}],"predecessor-version":[{"id":20723,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/20691\/revisions\/20723"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=20691"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=20691"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=20691"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}What you need to know before you take Pentacarinate<\/h2>\n\n\n\n
Do not use Pentacarinate<\/h2>\n\n\n\n
Warnings and cautions<\/h2>\n\n\n\n
Other medicines and Pentacarinate<\/h2>\n\n\n\n
Pregnancy and breastfeeding<\/h2>\n\n\n\n
Driving and using machines<\/h2>\n\n\n\n
How to take Pentacarinate<\/h2>\n\n\n\n
Possible side effects<\/h2>\n\n\n\n
How to store Pentacarinat<\/h2>\n\n\n\n
Other information<\/h2>\n\n\n\n