{"id":20681,"date":"2022-04-08T16:56:20","date_gmt":"2022-04-08T16:56:20","guid":{"rendered":"https:\/\/zeepedia.com\/?p=20681"},"modified":"2022-04-11T10:23:54","modified_gmt":"2022-04-11T10:23:54","slug":"pemetrexed-medac-2","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/pemetrexed-medac-2\/","title":{"rendered":"Pemetrexed medac &#8211; Pemetrexed uses, dose and side effects"},"content":{"rendered":"\n<p>100 mg, 500 mg, 1,000 mg&nbsp;powder for concentrate for&nbsp;solution for&nbsp;infusion<br>pemetrexed<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Pemetrexed medac is and what it is used for<\/h2>\n\n\n\n<p>Pemetrexed medac is a medicine used to treat cancer.<\/p>\n\n\n\n<p>Pemetrexed medac is given together with cisplatin, another anti-cancer medicine, for the treatment of malignant pleural mesothelioma, a form of lung cancer, to patients who have not previously received anticancer medicine.<\/p>\n\n\n\n<p>Pemetrexed medac is also used with cisplatin in the initial treatment of advanced lung cancer.<\/p>\n\n\n\n<p>Pemetrexed can be prescribed to you if you have advanced lung cancer and your disease has responded to treatment or if it is largely unchanged after initial drug treatment.<\/p>\n\n\n\n<p>In addition, Pemetrexed medac is used to treating advanced lung cancer whose disease has progressed after other previous drug treatments have been used.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before using Pemetrexed medac<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Pemetrexed medac:<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to pemetrexed or any of the other ingredients of this medicine (listed in section 6).<\/li><li>if you are breastfeeding.\u00a0You should stop breastfeeding during treatment with Pemetrexed medac.<\/li><li>if you have recently been vaccinated or are just about to be vaccinated against yellow fever.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Before using Pemetrexed medac, talk to your doctor or pharmacist about:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>you have or have had kidney problems, as you may not be able to get Pemetrexed medac.\u00a0Before each\u00a0infusion, blood samples will be taken to find out if the function of the kidneys and liver is sufficient and to check that the amount of\u00a0blood cells\u00a0is sufficient to receive Pemetrexed medac.\u00a0Your doctor may choose to change the\u00a0dose\u00a0or postpone your treatment depending on your general condition and if your blood levels are too low.\u00a0If you are also taking cisplatin, your doctor will make sure that you have been given enough fluids and that you will receive appropriate treatment before and after the cisplatin treatment to prevent vomiting.<\/li><li>you have received radiation therapy or if such treatment is planned, like radiation therapy and Pemetrexed medac may cause immediate or late\u00a0side effects.<\/li><li>you have recently been vaccinated, as Pemetrexed medac in connection with vaccination may give rise to undesirable reactions.<\/li><li>if you have or have previously had, heart disease.<\/li><li>you have fluid accumulation around your lung as your doctor may decide to remove the fluid before treatment with Pemetrexed medac.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Children and young people<\/h2>\n\n\n\n<p>This medicine should not be used by children or adolescents as there is no experience with the medicine in children and adolescents under 18 years of age.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Pemetrexed medac<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.<\/p>\n\n\n\n<p>In particular, tell your doctor if you are taking any medicine for pain or\u00a0inflammation\u00a0(swelling), such as so-called non-steroidal anti-inflammatory drugs (\u00a0NSAIDs\u00a0), including over-the-counter medicines (such as\u00a0ibuprofen\u00a0).\u00a0There are many different types of these drugs with varying duration of action.\u00a0Knowing the date of the planned\u00a0infusion\u00a0of Pemetrexed medac and\/or renal function status, your doctor will need to advise you on which medicines to take and when to take them.\u00a0If you are not sure, ask your doctor or\u00a0pharmacist\u00a0if any of your medicines are\u00a0NSAIDs.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, breastfeeding, and fertility<\/h2>\n\n\n\n<p><strong>Pregnancy<\/strong><\/p>\n\n\n\n<p>If you are pregnant, breastfeeding or think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.\u00a0Treatment with Pemetrexed medac should be avoided during pregnancy.\u00a0Your doctor will discuss any possible risks when Pemetrexed medac is given during pregnancy.\u00a0Women should use effective contraception during treatment with Pemetrexed medac.<\/p>\n\n\n\n<p><strong>Breast-feeding<\/strong><\/p>\n\n\n\n<p>You should not breastfeed during treatment with Pemetrexed medac.\u00a0Ask your doctor when it is safe to start breastfeeding again after stopping treatment.<\/p>\n\n\n\n<p><strong>Fertility<\/strong><\/p>\n\n\n\n<p>Men are advised not to have children during and up to 6 months after Pemetrexed medac treatment and should therefore use an effective method of contraception during Pemetrexed medac treatment and up to 6 months after stopping treatment.\u00a0If you plan to have children during treatment or the following 6 months after treatment, consult your doctor or\u00a0pharmacist.\u00a0You may want to seek advice on sperm preservation before starting treatment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Treatment with Pemetrexed medac may make you feel tired.&nbsp;Be careful when driving or using machines.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pemetrexed medac contains sodium<\/h2>\n\n\n\n<p>Pemetrexed medac 100 mg<\/p>\n\n\n\n<p>This medicine contains less than 1 mmol (23 mg)\u00a0sodium\u00a0per 100 mg\u00a0vial, ie is essential &#8216;sodium-free&#8217;.<\/p>\n\n\n\n<p>Pemetrexed medac 500 mg<\/p>\n\n\n\n<p>This medicine contains 54 mg of\u00a0sodium\u00a0(the main ingredient in table salt\/table salt) per 500 mg\u00a0vial.\u00a0This corresponds to 2.70% of the maximum recommended daily\u00a0sodium\u00a0intake for adults.<\/p>\n\n\n\n<p>Pemetrexed medac 1,000 mg<\/p>\n\n\n\n<p>This medicine contains 108 mg of\u00a0sodium\u00a0(the main ingredient in common salt\/table salt) per 1,000 mg\u00a0vial.\u00a0This corresponds to 5.40% of the highest recommended daily intake of\u00a0sodium\u00a0for adults.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to use Pemetrexed medac<\/h2>\n\n\n\n<p>Pemetrexed medac is given at a recommended\u00a0dose\u00a0of 500 mg per square meter of body surface area.\u00a0Your height and weight are used to calculate the body surface area.\u00a0Your doctor will use the measurement of your body surface area to calculate the correct\u00a0dose\u00a0for you.\u00a0This\u00a0dose\u00a0can be adjusted or the treatment can be postponed depending on blood levels and your general condition.\u00a0A hospital pharmacist, nurse, or doctor will have mixed the Pemetrexed medac powder in\u00a0sterile\u00a0sodium chloride 9 mg\/ml (0.9%) solution before giving it to you.<\/p>\n\n\n\n<p>Pemetrexed medac is always given as&nbsp;an infusion&nbsp;into a friend.&nbsp;Infusion&nbsp;one lasts for about 10 minutes.<\/p>\n\n\n\n<p><strong>Then Pemetrexed medac is given in combination with cisplatin<\/strong><\/p>\n\n\n\n<p>Your doctor or hospital pharmacist will have calculated the required&nbsp;dose&nbsp;using your height and weight.&nbsp;Cisplatin is also given as&nbsp;an infusion&nbsp;into a vein and is given approximately 30 minutes after the end of the Pemetrexed medac infusion.&nbsp;Infusion&nbsp;one of cisplatin lasts for about 2 hours.<\/p>\n\n\n\n<p>You usually receive&nbsp;an infusion&nbsp;once every three weeks.<\/p>\n\n\n\n<p><strong>Other drugs<\/strong><\/p>\n\n\n\n<p><em>Corticosteroid&nbsp;is<\/em><\/p>\n\n\n\n<p>Your doctor will prescribe steroid tablets (equivalent to 4 mg <a href=\"https:\/\/zeepedia.com\/medical\/medicines\/toflacort\/\">dexamethasone<\/a> twice daily).\u00a0You should take these tablets the day before, on the day of treatment, and the day after treatment with Pemetrexed medac.\u00a0The tablets are given to reduce the frequency and severity of the skin reactions that may occur during cancer treatment.<\/p>\n\n\n\n<p><em>Vitamin supplement<\/em><\/p>\n\n\n\n<p>Your doctor will prescribe a\u00a0preparation\u00a0of\u00a0<a href=\"https:\/\/zeepedia.com\/medical\/medicines\/triobe\/\">folic acid<\/a>\u00a0(\u00a0vitamin\u00a0) to be taken by mouth or a multivitamin preparation containing\u00a0folic acid\u00a0(350-1000 \u00b5g) that you should take once a day during treatment with Pemetrexed medac.\u00a0You should take at least 5\u00a0doses\u00a0during the seven days before the first\u00a0dose\u00a0of one of the Pemetrexed medac.\u00a0You should continue to take\u00a0folic acid\u00a0for 21 days after the last Pemetrexed\u00a0medication.\u00a0You will also receive a\u00a0vitamin\u00a0B\u00a012\u00a0injection\u00a0(\u00a01,000 \u00b5g) the week before Pemetrexed medac\u00a0infusion done and then approximately every 9 weeks (equivalent to 3 courses of treatment with Pemetrexed medac).\u00a0Vitamin\u00a0B\u00a0<sub>12<\/sub>\u00a0and\u00a0folic acid\u00a0are given to reduce the possible harmful effects of cancer treatment.<\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p>You should contact your doctor immediately if you notice any of the following side effects:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Fever or\u00a0infection\u00a0(common or very common): if you have a temperature of 38 \u00b0 C or more, sweating, or other signs of an\u00a0infection\u00a0(because you may have a lower\u00a0white blood cell count\u00a0than normal, which is very common).\u00a0Infection\u00a0one (blood poisoning) can be serious and lead to death.<\/li><li>If you start to feel chest pain (common) or have a fast heart rate (less common).<\/li><li>If you feel pain,\u00a0redness, swelling, or soreness in your mouth (very common).<\/li><li>Allergic reaction: if you get a rash (very common) \/ burning or stinging sensation (common) or fever (common).\u00a0Skin reactions can be serious and lead to death (rare).\u00a0Contact your doctor if you get a lot of rash,\u00a0itching,\u00a0or blisters (\u00a0Stevens-Johnson\u00a0syndrome or\u00a0toxic epidermal necrolysis\u00a0).<\/li><li>If you get tired, feel weak, get short of breath easily, or if you look pale (because you may have less\u00a0hemoglobin\u00a0than normal, which is very common).<\/li><li>If it bleeds from the gums, nose, or mouth or you get any bleeding that does not want to stop, reddish or pinkish urine, unexpected bruising (because you may have fewer\u00a0platelets\u00a0than normal, which is common).<\/li><li>If you experience sudden shortness of breath, intense chest pain, or cough with bloody cough (less common) (may indicate a blockage in the blood vessels of the lungs).<\/li><\/ul>\n\n\n\n<p>The following&nbsp;side effects&nbsp;may occur during treatment with pemetrexed:<\/p>\n\n\n\n<p><em>Very common (may affect more than 1 user in 10)<\/em><\/p>\n\n\n\n<p>Infection<\/p>\n\n\n\n<p>Sore throat<\/p>\n\n\n\n<p>Low&nbsp;neutrophil count&nbsp;(&nbsp;white blood cell&nbsp;type )<\/p>\n\n\n\n<p>Low&nbsp;white blood cell count<\/p>\n\n\n\n<p>Low hemoglobin (&nbsp;anemia&nbsp;)<\/p>\n\n\n\n<p>Pain,\u00a0redness, swelling, or soreness in the mouth<\/p>\n\n\n\n<p>Decreased appetite<\/p>\n\n\n\n<p>Vomiting<\/p>\n\n\n\n<p>Diarrhea<\/p>\n\n\n\n<p>Nausea<\/p>\n\n\n\n<p>Rash<\/p>\n\n\n\n<p>Flaking skin<\/p>\n\n\n\n<p>Abnormal blood counts showing&nbsp;reduced&nbsp;kidney function<\/p>\n\n\n\n<p>Fatigue (fatigue)<\/p>\n\n\n\n<p><em>Common (may affect up to 1 in 10 people)<\/em><\/p>\n\n\n\n<p>Blood infection<\/p>\n\n\n\n<p>Fever with low&nbsp;neutrophil count&nbsp;(&nbsp;white blood cell&nbsp;type )<\/p>\n\n\n\n<p>Reduced&nbsp;platelet count<\/p>\n\n\n\n<p>Allergic reaction<\/p>\n\n\n\n<p>Dehydration<\/p>\n\n\n\n<p>Taste changes<\/p>\n\n\n\n<p>Muscle weakness due to damage to motor nerves, especially in the arms and legs<\/p>\n\n\n\n<p>Loss of sensation, burning pain, and unsteady gait due to damage to sensory nerves<\/p>\n\n\n\n<p>Dizziness<\/p>\n\n\n\n<p>Inflammation&nbsp;or swelling of the conjunctiva (&nbsp;membrane&nbsp;at the end of the eyelids and covering the eyes white)<\/p>\n\n\n\n<p>Dry eyes<\/p>\n\n\n\n<p>Tear-filled eyes<\/p>\n\n\n\n<p>Dried&nbsp;conjunctiva&nbsp;(&nbsp;membrane&nbsp;on the outer part of the eyelids and covering the eyes white and&nbsp;cornea&nbsp;(the clear layer that protects the&nbsp;iris&nbsp;and&nbsp;pupil&nbsp;)<\/p>\n\n\n\n<p>Swollen eyelids<\/p>\n\n\n\n<p>Eye problems, such as dryness, tearing, irritation, and\/or pain.<\/p>\n\n\n\n<p>Heart failure&nbsp;(a condition that affects the pumping power of your heart muscle)<\/p>\n\n\n\n<p>Irregular heartbeat<\/p>\n\n\n\n<p>Indigestion<\/p>\n\n\n\n<p>Constipation<\/p>\n\n\n\n<p>Abdominal pain<\/p>\n\n\n\n<p>Liver: increase in the substances in the blood produced by the liver<\/p>\n\n\n\n<p>Increased skin pigmentation<\/p>\n\n\n\n<p>Itching<\/p>\n\n\n\n<p>Rash on the body therewith red marks<\/p>\n\n\n\n<p>Hair loss<\/p>\n\n\n\n<p>Hives<\/p>\n\n\n\n<p>Kidney failure<\/p>\n\n\n\n<p>Decreased renal function<\/p>\n\n\n\n<p>Fever<\/p>\n\n\n\n<p>Pain<\/p>\n\n\n\n<p>Excess fluid in body tissue, which causes swelling<\/p>\n\n\n\n<p>Chest pain<\/p>\n\n\n\n<p>Inflammation&nbsp;and ulceration of the mucous membranes that line the digestive tract<\/p>\n\n\n\n<p><em>Uncommon (may affect up to 1 in 100 people)<\/em><\/p>\n\n\n\n<p>Reduction in the number of red and&nbsp;white blood cells&nbsp;and&nbsp;platelets<\/p>\n\n\n\n<p>Stroke<\/p>\n\n\n\n<p>Type of&nbsp;stroke&nbsp;when an&nbsp;artery&nbsp;to the brain is blocked<\/p>\n\n\n\n<p>Bleeding inside the skull<\/p>\n\n\n\n<p>Angina (Chest pain caused by decreased blood flow to the heart)<\/p>\n\n\n\n<p>Myocardial infarction<\/p>\n\n\n\n<p>Narrowing or blockage of the coronary arteries<\/p>\n\n\n\n<p>Elevated heart rate<\/p>\n\n\n\n<p>Reduced blood distribution to the limbs<\/p>\n\n\n\n<p>Blood clots in the pulmonary blood vessels (&nbsp;pulmonary embolism&nbsp;)<\/p>\n\n\n\n<p>Inflammation&nbsp;and scarring of the lungs with respiratory problems<\/p>\n\n\n\n<p>Passage of bright red blood from the anus<\/p>\n\n\n\n<p>Bleeding in the gastrointestinal tract<\/p>\n\n\n\n<p>Broken intestine<\/p>\n\n\n\n<p>Inflammation&nbsp;of the esophageal&nbsp;mucosa&nbsp;(esophagus)<\/p>\n\n\n\n<p>Colitis&nbsp;(&nbsp;inflammation&nbsp;of the wall of the colon, which may be accompanied by bleeding from the intestines or&nbsp;rectum&nbsp;(seen only in combination with cisplatin)<\/p>\n\n\n\n<p>Inflammation,\u00a0edema\u00a0,\u00a0erythema,\u00a0and\u00a0erosion\u00a0of the mucosal surface of the esophagus caused by radiation therapy<\/p>\n\n\n\n<p>Inflammation&nbsp;of the lung caused by radiation therapy<\/p>\n\n\n\n<p><em>Rare (may affect up to 1 in 1,000 people)<\/em><\/p>\n\n\n\n<p>Destruction of&nbsp;red blood cells<\/p>\n\n\n\n<p>Anaphylactic&nbsp;shock&nbsp;(severe&nbsp;allergic reaction&nbsp;)<\/p>\n\n\n\n<p>Inflammatory conditions of the liver<\/p>\n\n\n\n<p>Redness of the skin<\/p>\n\n\n\n<p>Skin rash that may occur on skin that has previously been exposed to radiation therapy.<\/p>\n\n\n\n<p><em>Very rare (may affect up to 1 in 10,000 people)<\/em><\/p>\n\n\n\n<p>Infection&nbsp;of skin and&nbsp;soft&nbsp;tissue<\/p>\n\n\n\n<p>Stevens-Johnson syndrome (a type of severe reaction to skin and mucous membranes that can be life-threatening)<\/p>\n\n\n\n<p>Toxic epidermal necrolysis&nbsp;(a type of severe skin reaction that can be life-threatening)<\/p>\n\n\n\n<p>An autoimmune\u00a0condition that results in skin rashes and blisters on legs, arms, and abdomen<\/p>\n\n\n\n<p>Inflammation&nbsp;of the skin characterized by the presence of bullous conditions with fluid-filled blistering)<\/p>\n\n\n\n<p>Fragile skin, blisters, and\u00a0erosion\u00a0as well as scarring of the skin<\/p>\n\n\n\n<p>Redness, pain, and swelling mainly in the lower legs<\/p>\n\n\n\n<p>Inflammation&nbsp;of the skin and fat under the skin (pseudocellulitis)<\/p>\n\n\n\n<p>Inflammation&nbsp;of the skin (&nbsp;dermatitis&nbsp;)<\/p>\n\n\n\n<p>Skin that becomes inflamed, itchy, red, cracked, and rough<\/p>\n\n\n\n<p>Intense itchy spots<\/p>\n\n\n\n<p><em>Has been reported (occurs in an unknown number of users)<\/em><\/p>\n\n\n\n<p>A form of&nbsp;diabetes&nbsp;that is primarily based on kidney&nbsp;pathology<\/p>\n\n\n\n<p>Kidney disorder involving tubular epithelial cells (which form renal tubules) death.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Pemetrexed medac<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the label and carton after EXP.<\/p>\n\n\n\n<p>No special storage instructions.<\/p>\n\n\n\n<p>Dissolved drug and infusion solution: The drug should be used immediately.\u00a0Chemical and physical shelf life for 24 hours in a refrigerator (2-8 \u00b0 C) has been demonstrated for the reconstituted\u00a0stock solution\u00a0and the infusion solution of pemetrexed if\u00a0reconstituted\u00a0according to the instructions.<\/p>\n\n\n\n<p>This medicine is for single use only.\u00a0Any unused solution should be disposed of by local requirements.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the pack and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<p>The active substance is pemetrexed.<\/p>\n\n\n\n<p>Pemetrexed medac 100 mg: One&nbsp;vial&nbsp;contains 100 mg pemetrexed (as disodium pemetrexedhemipentahydrate).<\/p>\n\n\n\n<p>Pemetrexed medac 500 mg: One&nbsp;vial&nbsp;contains 500 mg of pemetrexed (as disodium pemetrexedhemipentahydrate).<\/p>\n\n\n\n<p>Pemetrexed medac 1,000 mg: One&nbsp;vial&nbsp;contains 1,000 mg of pemetrexed (as disodium pemetrexedhemipentahydrate).<\/p>\n\n\n\n<p>After reconstitution, the solution contains 25 mg \/ ml pemetrexed.<\/p>\n\n\n\n<p>The other ingredients are mannitol,\u00a0hydrochloric acid,\u00a0and sodium hydroxide, see section 2 &#8220;Pemetrexed medac contains sodium&#8221;.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>Pemetrexed medac is a powder for concentrate for solution for&nbsp;infusion&nbsp;in a&nbsp;vial&nbsp;with a rubber stopper.<\/p>\n\n\n\n<p>It is a white to light yellow powder.<\/p>\n\n\n\n<p>The pack contains a\u00a0vial\u00a0of 100, 500, or 1,000 mg pemetrexed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorisation Holder<\/h2>\n\n\n\n<p>medac<\/p>\n\n\n\n<p>Society for Clinical Specialties MBH<\/p>\n\n\n\n<p>Theater.\u00a06<\/p>\n\n\n\n<p>22880 Wedel<\/p>\n\n\n\n<p>Germany<\/p>\n\n\n\n<p>tel .: +49 4103 8006-0<\/p>\n\n\n\n<p>fax: +49 4103 8006-100<\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>Synthon Hispania SLC \/ Castell\u00f3 n \u00b0 1, Pol.&nbsp;Las Salinas<\/p>\n\n\n\n<p>08830 Sant Boi de Llobregat<\/p>\n\n\n\n<p>Barcelona<\/p>\n\n\n\n<p>Spain<\/p>\n\n\n\n<p>tel .: +34 936401516<\/p>\n\n\n\n<p>fax: +34 936401146<\/p>\n\n\n\n<p>Synthon, sro<\/p>\n\n\n\n<p>Brn\u0115nsk\u00e1 32 \/ \u010dp.&nbsp;597<\/p>\n\n\n\n<p>67801 Blansko<\/p>\n\n\n\n<p>Czech Republic<\/p>\n\n\n\n<p>tel .: +420 516 427 311<\/p>\n\n\n\n<p>fax: +420 516 417 350<\/p>\n\n\n\n<p>medac<\/p>\n\n\n\n<p>Society for Clinical Specialties MBH<\/p>\n\n\n\n<p>Theater.\u00a06<\/p>\n\n\n\n<p>22880 Wedel<\/p>\n\n\n\n<p>Germany<\/p>\n\n\n\n<p>tel .: +49 4103 8006-0<\/p>\n\n\n\n<p>fax: +49 4103 8006-100<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Pemetrexed medac is given together with cisplatin, another anticancer medicine, for the treatment of malignant pleural mesothelioma, a form of lung cancer, to patients who have not previously received anticancer medicine.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,18527],"tags":[21095,21115,10012,21111,21114,10015,10013,21112,10014,21113],"class_list":["post-20681","post","type-post","status-publish","format-standard","hentry","category-medicines","category-p","tag-benefits-of-pemetrexed","tag-benefits-of-pemetrexed-medac","tag-pemetrexed","tag-pemetrexed-medac","tag-pemetrexed-medac-side-effects","tag-pemetrexed-side-effects","tag-what-is-pemetrexed","tag-what-is-pemetrexed-medac","tag-what-pemetrexed-is-used-for","tag-what-pemetrexed-medac-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/20681","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=20681"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/20681\/revisions"}],"predecessor-version":[{"id":20729,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/20681\/revisions\/20729"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=20681"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=20681"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=20681"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}