{"id":20679,"date":"2022-04-08T16:54:17","date_gmt":"2022-04-08T16:54:17","guid":{"rendered":"https:\/\/zeepedia.com\/?p=20679"},"modified":"2022-04-11T10:23:58","modified_gmt":"2022-04-11T10:23:58","slug":"pemetrexed-hospira-2","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/pemetrexed-hospira-2\/","title":{"rendered":"Pemetrexed Hospira &#8211; Pemetrexed uses, dose and side effects"},"content":{"rendered":"\n<p>25 mg \/ ml&nbsp;concentrate for&nbsp;solution for&nbsp;infusion<br>pemetrexed<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Pemetrexed Hospira is and what it is used for<\/h2>\n\n\n\n<p>Pemetrexed Hospira is a medicine used to treat cancer.<\/p>\n\n\n\n<p>Pemetrexed Hospira is co-administered with cisplatin, another anti-cancer drug, for the treatment of malignant pleural mesothelioma, a form of lung sac cancer, in patients who have not previously received anti-cancer drug therapy.<\/p>\n\n\n\n<p>Pemetrexed Hospira is also used with cisplatin in the initial treatment of advanced lung cancer.<\/p>\n\n\n\n<p>Pemetrexed Hospira can be prescribed to you if you have advanced lung cancer and your illness has responded to treatment or if it is largely unchanged after initial drug treatment.<\/p>\n\n\n\n<p>In addition, Pemetrexed Hospira is used to treat advanced lung cancer whose disease has progressed, after other previous drug treatments have been used.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before you use Pemetrexed Hospira<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Pemetrexed Hospira<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic (hypersensitive) to pemetrexed or any of the other ingredients of this medicine (listed in section 6).<\/li><li>if you are breastfeeding.\u00a0You should stop breastfeeding during treatment with Pemetrexed Hospira.<\/li><li>if you have recently been vaccinated or are just about to be vaccinated against yellow fever.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before taking Pemetrexed Hospira.<\/p>\n\n\n\n<p>Talk to your doctor or pharmacist if you have or have had kidney problems, as you may not be able to get Pemetrexed Hospira.<\/p>\n\n\n\n<p>Before each\u00a0infusion, blood samples will be taken to find out if the function of the kidneys and liver is sufficient and to check that the amount of blood cells is sufficient to obtain Pemetrexed Hospira.\u00a0Your doctor may choose to change the\u00a0dose\u00a0or postpone your treatment depending on your general condition and if your blood levels are too low.\u00a0If you are also receiving cisplatin, your doctor will make sure that you have been given enough fluids and that you will receive appropriate treatment before and after the cisplatin treatment to prevent vomiting.<\/p>\n\n\n\n<p>If you have received radiation therapy or if such treatment is planned, tell your doctor, like radiation therapy and Pemetrexed Hospira may cause immediate or late\u00a0side effects.<\/p>\n\n\n\n<p>If you have recently been vaccinated, you should tell your doctor, as Pemetrexed Hospira in combination with vaccination may cause unwanted reactions.<\/p>\n\n\n\n<p>Tell your doctor if you have, or have previously had, heart disease.<\/p>\n\n\n\n<p>If you have fluid accumulation around your lungs, your doctor may decide to remove the fluid before treatment with Pemetrexed Hospira.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children and young people<\/h2>\n\n\n\n<p>This medicine should not be used by children or adolescents as there is no experience with the medicine in children and adolescents under 18 years of age.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Pemetrexed Hospira<\/h2>\n\n\n\n<p>Tell your doctor if you are taking any medicine for pain or inflammation (swelling), such as so-called non-steroidal anti-inflammatory drugs (\u00a0NSAIDs\u00a0), including over-the-counter medicines (such as ibuprofen).\u00a0There are many different types of these drugs with varying duration of action.\u00a0Knowing the date of the planned\u00a0infusion\u00a0of pemetrexed and\/or renal function status, your doctor will need to advise you on which medicines you can take and when you can take them.<\/p>\n\n\n\n<p>If you are not sure, ask your doctor or pharmacist if any of your medicines are NSAIDs.<\/p>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking or have recently taken or might take any other medicines, including medicines obtained without a prescription.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, breastfeeding, and fertility<\/h2>\n\n\n\n<p><strong>Pregnancy<\/strong><\/p>\n\n\n\n<p>If you are pregnant, think you may be pregnant, or are planning to have a baby, ask your doctor for advice before taking this medicine.\u00a0Treatment with pemetrexed should be avoided during pregnancy.\u00a0Your doctor will discuss any risks involved in taking pemetrexed during pregnancy.\u00a0Women should use effective contraception during treatment with pemetrexed.<\/p>\n\n\n\n<p><strong>Breast-feeding<\/strong><\/p>\n\n\n\n<p>Tell your doctor if you are breastfeeding.\u00a0Breast-feeding should be discontinued during treatment with pemetrexed.<\/p>\n\n\n\n<p><strong>Fertility<\/strong><\/p>\n\n\n\n<p>Men are advised not to have children during and up to 6 months after pemetrexed treatment and should therefore use an effective method of contraception during pemetrexed treatment and up to 6 months after stopping treatment.&nbsp;If you plan to have children during treatment or the following 6 months after treatment, consult a doctor or pharmacist.&nbsp;You may want to seek advice on sperm preservation before starting treatment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Treatment with Pemetrexed Hospira may make you feel tired.&nbsp;Be careful when driving or using machines.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pemetrexed Hospira contains sodium<\/h2>\n\n\n\n<p>One 4 ml\u00a0vial\u00a0contains less than 1 mmol (23 mg)\u00a0sodium, ie essentially &#8216;sodium-free&#8217;.<\/p>\n\n\n\n<p>One 20 ml\u00a0vial\u00a0contains approximately 54 mg of\u00a0sodium\u00a0(the main ingredient in table salt\/table salt).\u00a0This corresponds to 2.7% of the maximum recommended daily\u00a0sodium\u00a0intake for adults.<\/p>\n\n\n\n<p>A 40 ml\u00a0vial\u00a0contains approximately 108 mg of\u00a0sodium\u00a0(the main ingredient in table salt\/table salt).\u00a0This corresponds to 5.4% of the maximum recommended daily intake of\u00a0sodium\u00a0for adults.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to use Pemetrexed Hospira<\/h2>\n\n\n\n<p>Pemetrexed Hospira is given at a\u00a0dose\u00a0of 500 mg per square meter of body surface area.\u00a0Your height and weight are used to calculate the body surface area.\u00a0Your doctor will use the measurement of your body surface area to calculate the correct\u00a0dose\u00a0for you.\u00a0This\u00a0dose\u00a0can be adjusted or the treatment can be postponed depending on blood levels and your general condition.\u00a0A hospital pharmacist, nurse, or doctor will have mixed the Pemetrexed Hospira concentrate in\u00a0sterile\u00a0sodium chloride 9 mg\/ml (0.9%) solution before giving it to you.<\/p>\n\n\n\n<p>Pemetrexed Hospira is always given as\u00a0an infusion\u00a0to a friend.\u00a0Infusion\u00a0one lasts for about 10 minutes.<\/p>\n\n\n\n<p>When Pemetrexed Hospira is given in combination with cisplatin:<\/p>\n\n\n\n<p>Your doctor or hospital pharmacist will have calculated the required&nbsp;dose&nbsp;using your height and weight.&nbsp;Cisplatin is also given as&nbsp;an infusion&nbsp;into a vein and is given approximately 30 minutes after the end of the Pemetrexed Hospira infusion.&nbsp;Infusion&nbsp;one of cisplatin lasts for about 2 hours.<\/p>\n\n\n\n<p>You usually receive&nbsp;an infusion&nbsp;once every three weeks.<\/p>\n\n\n\n<p>Other medicines:<\/p>\n\n\n\n<p>Corticosteroids: Your doctor will prescribe steroid tablets (equivalent to 4 milligrams of <a href=\"https:\/\/zeepedia.com\/medical\/medicines\/toflacort\/\">dexamethasone<\/a> twice daily).\u00a0You should take these tablets the day before, on the day of treatment, and the day after treatment with Pemetrexed Hospira.\u00a0The tablets are given to reduce the frequency and severity of the skin reactions that may occur during cancer treatment.<\/p>\n\n\n\n<p>Vitamin supplement: Your doctor will prescribe a preparation of <a href=\"https:\/\/zeepedia.com\/medical\/medicines\/triobe\/\">folic acid<\/a> (\u00a0vitamin\u00a0) to be taken by mouth or a multivitamin preparation containing folic acid (350 to 1000 micrograms) that you skate once a day during treatment with Pemetrexed Hospira.\u00a0You will miss at least 5 doses during the seven days preceding the first dose of Pemetrexed Hospira.\u00a0You should continue to take folic acid for 21 days after the last\u00a0dose\u00a0of Pemetrexed Hospira.\u00a0You will also receive a\u00a0vitamin\u00a0B\u00a0<sub>12<\/sub>\u00a0injection (1000 micrograms) the week before Pemetrexed Hospira\u00a0infusion\u00a0one and then approximately every 9 weeks (equivalent to 3 courses of Pemetrexed Hospira).\u00a0Vitamin B\u00a0<sub>12<\/sub>\u00a0and\u00a0folic acid are given to reduce the potentially harmful effects of cancer treatment.<\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or pharmacist<strong>.<\/strong><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p>You should contact your doctor immediately if you notice any of the following side effects:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Fever or infection (common or very common): if you have a temperature of 38\u00ba C or more, sweating, or other signs of an infection (because you may have a lower white blood cell count than normal, which is very common).\u00a0Infection\u00a0one (blood poisoning) can be serious and lead to death.<\/li><li>If you start to feel chest pain (common) or have a fast heart rate (less common).<\/li><li>If you feel pain, redness, swelling, or soreness in your mouth (very common).<\/li><li>Allergic reaction:\u00a0if you get a rash (very common) \/ burning or stinging sensation (common) or fever (common).\u00a0Skin reactions can be serious and lead to death (rare).\u00a0Contact your doctor if you get a lot of rash,\u00a0itching,\u00a0or blisters (\u00a0Stevens-Johnson\u00a0syndrome or toxic epidermal necrolysis).<\/li><li>If you get tired, have a feeling of fainting, become short of breath, or if you look pale (because you may have less\u00a0hemoglobin\u00a0than normal, which is very common).<\/li><li>If it bleeds from the gums, nose, or mouth or you get any bleeding that does not want to stop, reddish or pinkish urine, unexpected bruising (because you may have fewer platelets than normal, which is common).<\/li><li>If you experience sudden shortness of breath, intense chest pain, or cough with bloody cough (less common) (may indicate a blockage in the blood vessels of the lungs).<\/li><\/ul>\n\n\n\n<p>Side effects of Pemetrexed Hospira that may occur:<\/p>\n\n\n\n<p><em>Very common (may affect more than 1 user in 10)<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Infection<\/li><li>Sore throat<\/li><li>Low\u00a0neutrophil count\u00a0(\u00a0white blood cell\u00a0type )<\/li><li>Low\u00a0white blood cell count<\/li><li>Low hemoglobin (\u00a0anemia\u00a0)<\/li><li>Pain,\u00a0redness, swelling, or soreness in the mouth<\/li><li>Decreased appetite<\/li><li>Vomiting<\/li><li>Diarrhea<\/li><li>Nausea<\/li><li>Rash<\/li><li>Flaking skin<\/li><li>Abnormal blood counts showing\u00a0reduced\u00a0kidney function<\/li><li>Fatigue (fatigue)<\/li><\/ul>\n\n\n\n<p><em>Common (may affect up to 1 in 10 people)<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Blood infection<\/li><li>Fever with low\u00a0neutrophil count\u00a0(\u00a0white blood cell\u00a0type )<\/li><li>Reduced\u00a0platelet count<\/li><li>Allergic reaction<\/li><li>Dehydration<\/li><li>Taste changes<\/li><li>Muscle weakness due to damage to motor nerves, especially in the arms and legs<\/li><li>Loss of sensation, burning pain, and unsteady gait due to damage to sensory nerves<\/li><li>Dizziness<\/li><li>Inflammation\u00a0or swelling of the conjunctiva (\u00a0membrane\u00a0at the outermost part of the eyelids and covering the whites of the eyes)<\/li><li>Dry eyes<\/li><li>Tear-filled eyes<\/li><li>Dried\u00a0conjunctiva\u00a0(\u00a0membrane\u00a0on the outer part of the eyelids and covering the whites of the eyes) and\u00a0cornea\u00a0(the clear layer that protects the\u00a0iris\u00a0and\u00a0pupil\u00a0)<\/li><li>Swollen eyelids<\/li><li>Eye problems, such as dryness, tearing, irritation, and\/or pain<\/li><li>Heart failure\u00a0(a condition that affects the pumping power of your heart muscle)<\/li><li>Irregular heartbeat<\/li><li>Indigestion<\/li><li>Constipation<\/li><li>Abdominal pain<\/li><li>Liver: increase in the substances in the blood produced by the liver<\/li><li>Increased skin pigmentation<\/li><li>Itching<\/li><li>Rash on the body therewith red marks<\/li><li>Hair loss<\/li><li>Hives<\/li><li>Kidney failure<\/li><li>Decreased renal function<\/li><li>Fever<\/li><li>Pain<\/li><li>Excess fluid in body tissue, which causes swelling<\/li><li>Chest pain<\/li><li>Inflammation\u00a0and ulceration of the mucous membranes that line the digestive tract<\/li><\/ul>\n\n\n\n<p><em>Uncommon (may affect up to 1 in 100 people)<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Reduction in the number of red and\u00a0white blood cells\u00a0and\u00a0platelets<\/li><li>Stroke<\/li><li>Type of\u00a0stroke\u00a0when an\u00a0artery\u00a0to the brain is blocked<\/li><li>Bleeding inside the skull<\/li><li>Angina (chest pain caused by decreased blood flow to the heart)<\/li><li>Myocardial infarction<\/li><li>Narrowing or blockage of the coronary arteries<\/li><li>Elevated heart rate<\/li><li>Reduced blood distribution to the limbs<\/li><li>Blood clots in the pulmonary blood vessels (\u00a0pulmonary embolism\u00a0)<\/li><li>Inflammation\u00a0and scarring of the lungs with respiratory problems<\/li><li>Passage of bright red blood from the anus<\/li><li>Bleeding in the gastrointestinal tract<\/li><li>Broken intestine<\/li><li>Inflammation\u00a0of the esophageal\u00a0mucosa\u00a0(esophagus)<\/li><li>Colitis\u00a0(\u00a0inflammation\u00a0of the wall of the colon), which may be accompanied by bleeding from the intestines or\u00a0rectum\u00a0(seen only in combination with cisplatin)<\/li><li>Inflammation,\u00a0edema,\u00a0erythema,\u00a0and\u00a0erosion\u00a0of the mucosal surface of the esophagus caused by radiation therapy<\/li><li>Inflammation\u00a0of the lung caused by radiation therapy<\/li><\/ul>\n\n\n\n<p><em>Rare (may affect up to 1 in 1,000 people)<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Destruction of&nbsp;red blood cells<\/li><li>Anaphylactic&nbsp;shock&nbsp;(severe&nbsp;allergic reaction&nbsp;)<\/li><li>Inflammatory conditions of the liver<\/li><li>Redness of the skin<\/li><li>Skin rash that may occur on skin that has previously been exposed to radiation therapy.<\/li><\/ul>\n\n\n\n<p><em>Very rare (may affect up to 1 in 10,000 people)<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Infection\u00a0of skin and soft tissue<\/li><li>Stevens-Johnson syndrome\u00a0(a type of severe reaction to skin and mucous membranes that can be life-threatening)<\/li><li>Toxic epidermal necrolysis\u00a0(a type of severe skin reaction that can be life-threatening)<\/li><li>An autoimmune\u00a0condition that results in skin rashes and blisters on legs, arms, and abdomen<\/li><li>Inflammation\u00a0of the skin characterized by the presence of bullous conditions with fluid-filled blistering)<\/li><li>Fragile skin, blisters, and\u00a0erosion\u00a0as well as scarring of the skin<\/li><li>Redness, pain, and swelling mainly in the lower legs<\/li><li>Inflammation\u00a0of the skin and fat under the skin (pseudocellulitis)<\/li><li>Inflammation\u00a0of the skin (\u00a0dermatitis\u00a0)<\/li><li>Skin that becomes inflamed, itchy, red, cracked, and rough<\/li><li>Intense itchy spots<\/li><\/ul>\n\n\n\n<p><em>Has been reported (occurs in an unknown number of users)<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>A form of&nbsp;diabetes&nbsp;that is primarily based on kidney&nbsp;pathology<\/li><li>Kidney disorder involving tubular epithelial cells (which form renal tubules) death.<\/li><\/ul>\n\n\n\n<p>You may get any of these symptoms and\/or ailments.\u00a0If you start to experience any of these\u00a0side effects, talk to your doctor as soon as possible.<\/p>\n\n\n\n<p>If you have any\u00a0side effects, talk to your doctor.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Pemetrexed Hospira<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the carton and vial label after EXP.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>This medicine has no special storage instructions.<\/p>\n\n\n\n<p>Infusion solution: Chemical and physical in-use durability of pemetrexed infusion solution has been demonstrated for up to 24 hours at 2 \u00b0 C-8 \u00b0 C.\u00a0From a microbiological perspective, the product should be used immediately after opening.\u00a0If not used immediately, in-use storage times and conditions before use is the responsibility of the user.\u00a0This storage should not be longer than 24 hours at 2 \u2013C \u2013 8 \u00baC.<\/p>\n\n\n\n<p>Drugs administered parenterally should be visually inspected for particulate matter and discoloration before\u00a0administration.\u00a0If particles are observed, the solution should not be administered.<\/p>\n\n\n\n<p>This medicine is for single use only.\u00a0Any unused solution should be disposed of following local requirements.<\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the pack and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<p>The active substance is pemetrexed.\u00a0One ml of concentrate contains pemetrexed disodium equivalent to 25 mg pemetrexed.\u00a0Further dilution must be performed by healthcare professionals before\u00a0administration.<\/p>\n\n\n\n<p>One&nbsp;vial&nbsp;of 4 ml concentrate contains pemetrexed disodium equivalent to 100 mg pemetrexed.<\/p>\n\n\n\n<p>One&nbsp;vial&nbsp;of 20 ml concentrate contains pemetrexed disodium equivalent to 500 mg pemetrexed.<\/p>\n\n\n\n<p>One&nbsp;vial&nbsp;of 40 ml concentrate contains pemetrexed disodium equivalent to 1000 mg pemetrexed.<\/p>\n\n\n\n<p>The other ingredients are monothioglycerol, sodium hydroxide (for\u00a0pH\u00a0adjustment), and water for\u00a0injection.\u00a0See also section 2 &#8220;Pemetrexed Hospira contains sodium&#8221;.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>Pemetrexed Hospira concentrate for solution for\u00a0infusion\u00a0(sterile concentrate) is a clear, colorless to the pale yellow or greenish-yellow solution that is practically free of visible particles in a\u00a0glass\u00a0vial.<\/p>\n\n\n\n<p>Each pack contains a&nbsp;vial&nbsp;of 100 mg \/ 4 ml, 500 mg \/ 20 ml or 1000 mg \/ 40 ml pemetrexed (as pemetrexed disodium).<\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p><strong>Marketing Authorisation Holder<\/strong><\/p>\n\n\n\n<p>Pfizer Europe MA EEIG<\/p>\n\n\n\n<p>Boulevard de la Plaine 17<\/p>\n\n\n\n<p>1050 Brussels<\/p>\n\n\n\n<p>Belgium<\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>Pfizer Service Company BVBA<\/p>\n\n\n\n<p>High Road 10<\/p>\n\n\n\n<p>1930 Zaventem<\/p>\n\n\n\n<p>Belgium<\/p>\n\n\n\n<p>Contact the representative of the marketing authorization holder to find out more about this medicine:<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td><strong>ASK<\/strong>Pfizer SA \/ NVTel: +32 2 554 62 11<\/td><td><strong>LT<\/strong>Pfizer Luxembourg SARL branches in LithuaniaTel.&nbsp;+ 370 52 51 4000<\/td><\/tr><tr><td><strong>BG<\/strong>Pfizer Luxembourg SARE, Clone of BulgariaTel: +359 2 970 4333<\/td><td><strong>LU<\/strong>Pfizer SA \/ NVTel: +32 2 554 62 11<\/td><\/tr><tr><td><strong>CZ<\/strong>Pfizer, spol.&nbsp;s roTel: + 420-283-004-111<\/td><td><strong>HU<\/strong>Pfizer Kft.Tel: + 36 1 488 37 00<\/td><\/tr><tr><td><strong>DK<\/strong>Pfizer ApSTel: + 45 44 20 11 00<\/td><td><strong>MT<\/strong>Drugsales LtdTel .: + 356 21 419 070\/1\/2<\/td><\/tr><tr><td><strong>THE<\/strong>PFIZER PHARMA GmbHTel: + 49 (0) 30 550055-51000<\/td><td><strong>NL<\/strong>Pfizer bvTel: +31 (0) 800 63 34 636<\/td><\/tr><tr><td><strong>EE<\/strong>Pfizer Luxembourg SARL Eesti subsidiaryTel: +372 666 7500<\/td><td><strong>NO<\/strong>Pfizer ASTel: +47 67 52 61 00<\/td><\/tr><tr><td><strong>EL<\/strong>Pfizer \u0395\u039b\u039b\u0391\u03a3 AE.:\u0397\u03bb .: +30 210 6785 800<\/td><td><strong>AT<\/strong>Pfizer Corporation Austria Ges.mbHTel: +43 (0) 1 521 15-0<\/td><\/tr><tr><td><strong>ES<\/strong>Pfizer, SLTel: +34 91 490 99 00<\/td><td><strong>PL<\/strong>Pfizer Polska Sp.&nbsp;z ooTel: +48 22 335 61 00<\/td><\/tr><tr><td><strong>FR<\/strong>PfizerTel: + 33 (0) 1 58 07 34 40<\/td><td><strong>PT<\/strong>Pfizer Laboratories, Lda.Tel: + 351 21 423 55 00<\/td><\/tr><tr><td><strong>HR<\/strong>Pfizer Croatia dooTel: +385 1 3908 777<\/td><td><strong>RO<\/strong>Pfizer Rom\u00e2nia SRL<br>Tel: +40 (0) 21 207 28 00<\/td><\/tr><tr><td><strong>IE<\/strong>Pfizer Healthcare IrelandTel: 1800 633 363 (toll free)+44 (0) 1304 616161<\/td><td><b>Pfizer<\/b> Luxembourg SARLPfizer, a company in the field of pharmaceuticals, LjubljanaTel: +386 (0) 1 52 11 400<\/td><\/tr><tr><td><strong>IS<\/strong>Icepharma hf.Phone: +354 540 8000<\/td><td><strong>SK<\/strong>Pfizer Luxembourg SARL, organizerTel: + 421\u20132\u20133355 5500<\/td><\/tr><tr><td><strong>IT<\/strong>Pfizer SrlTel: +39 06 33 18 21<\/td><td><strong>FI<\/strong>Pfizer OyPuh \/ Tel: +358 (0) 9 430 040<\/td><\/tr><tr><td><strong>CY<\/strong>Pfizer \u0391\u03bb\u03bb\u03ac\u03c2 \u0391.\u0395.&nbsp;(Cyprus Branch).:\u0397\u03bb .: +357 22817690<\/td><td><strong>SEE<\/strong>Pfizer ABTel: +46 (0) 8 550 520 00<\/td><\/tr><tr><td><strong>LV<\/strong>Pfizer Luxembourg SARL subsidiary Latvij\u0101Tel .: + 371 670 35 775<\/td><td><strong>UK (Northern Ireland)<\/strong>Pfizer LimitedTel: + 44 (0) 1304 616161<\/td><\/tr><\/tbody><\/table><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>Pemetrexed Hospira is co-administered with cisplatin, another anti-cancer drug, for the treatment of malignant pleural mesothelioma, a form of lung sac cancer, in patients who have not previously received anti-cancer drug therapy.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,18527],"tags":[21095,21120,10012,21116,21119,10015,10013,21117,21118,10014],"class_list":["post-20679","post","type-post","status-publish","format-standard","hentry","category-medicines","category-p","tag-benefits-of-pemetrexed","tag-benefits-of-pemetrexed-hospira","tag-pemetrexed","tag-pemetrexed-hospira","tag-pemetrexed-hospira-side-effects","tag-pemetrexed-side-effects","tag-what-is-pemetrexed","tag-what-is-pemetrexed-hospira","tag-what-pemetrexed-hospira-is-used-for","tag-what-pemetrexed-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/20679","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=20679"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/20679\/revisions"}],"predecessor-version":[{"id":20730,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/20679\/revisions\/20730"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=20679"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=20679"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=20679"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}