{"id":20675,"date":"2022-04-08T16:51:32","date_gmt":"2022-04-08T16:51:32","guid":{"rendered":"https:\/\/zeepedia.com\/?p=20675"},"modified":"2022-04-11T10:24:11","modified_gmt":"2022-04-11T10:24:11","slug":"pemetrexed-fresenius-kabi-2","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/pemetrexed-fresenius-kabi-2\/","title":{"rendered":"Pemetrexed Fresenius Kabi &#8211; Pemetrexed uses, dose and side effects"},"content":{"rendered":"\n<p>25 mg \/ ml concentrate for solution for infusion<br>pemetrexed<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Pemetrexed Fresenius Kabi is and what it is used for<\/h2>\n\n\n\n<p>Pemetrexed Fresenius Kabi is a medicine used to treat cancer.<\/p>\n\n\n\n<p>Pemetrexed Fresenius Kabi is co-administered with cisplatin, another anti-cancer drug, for the treatment of malignant pleural mesothelioma, a form of lung sac cancer, in patients who have not previously received anti-cancer drug therapy.<\/p>\n\n\n\n<p>Pemetrexed Fresenius Kabi is also used with cisplatin in the initial treatment of advanced lung cancer.<\/p>\n\n\n\n<p>Pemetrexed Fresenius Kabi can be prescribed to you if you have advanced lung cancer and your disease has responded to treatment or if it is largely unchanged after initial drug treatment.<\/p>\n\n\n\n<p>In addition, Pemetrexed Fresenius Kabi is used to treat advanced lung cancer whose disease has progressed, after other previous drug treatments have been used.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before using Pemetrexed Fresenius Kabi<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Pemetrexed Fresenius Kabi<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to pemetrexed or any of the other ingredients of this medicine (listed in section 6).<\/li><li>if you are breastfeeding, you should stop breastfeeding during treatment with Pemetrexed Fresenius Kabi.<\/li><li>if you have recently been vaccinated or are just about to be vaccinated against yellow fever.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before receiving Pemetrexed Fresenius Kabi.<\/p>\n\n\n\n<p>Talk to your doctor or pharmacist if you have or have had kidney problems, as you may not be able to get Pemetrexed Fresenius Kabi.<\/p>\n\n\n\n<p>Before each\u00a0infusion, blood samples will be taken to determine if the function of the kidneys and liver is sufficient and to check that the amount of\u00a0blood cells\u00a0is sufficient to obtain Pemetrexed Fresenius Kabi.\u00a0Your doctor may choose to change the\u00a0dose\u00a0or postpone your treatment depending on your general condition and if your blood levels are too low.\u00a0If you are also taking cisplatin, your doctor will make sure that you have been given enough fluids and that you will receive appropriate treatment before and after the cisplatin treatment to prevent vomiting.<\/p>\n\n\n\n<p>If you have received radiation therapy or if such treatment is planned, tell your doctor, like radiation therapy and Pemetrexed Fresenius Kabi may cause immediate or late\u00a0side effects.<\/p>\n\n\n\n<p>If you have recently been vaccinated, you should tell your doctor, as Pemetrexed Fresenius Kabi in connection with vaccination may cause unwanted reactions.<\/p>\n\n\n\n<p>Tell your doctor if you have, or have previously had, heart disease.<\/p>\n\n\n\n<p>If you have fluid accumulation around your lungs, your doctor may decide to remove the fluid before treatment with Pemetrexed Fresenius Kabi.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children and young people<\/h2>\n\n\n\n<p>This medicine should not be used by children or adolescents as there is no experience with the medicine in children and adolescents under 18 years of age.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Pemetrexed Fresenius Kabi<\/h2>\n\n\n\n<p>Tell your doctor if you are taking, have recently taken, or might take any medicine for pain or\u00a0inflammation\u00a0(swelling), such as so-called non-steroidal anti-inflammatory drugs (\u00a0NSAIDs\u00a0), including over-the-counter medicines (such as\u00a0ibuprofen\u00a0).\u00a0There are many different types of these drugs with varying duration of action.\u00a0With the knowledge of the date of the planned\u00a0infusion\u00a0of Pemetrexed Fresenius Kabi and\/or renal function status, your doctor must advise you on which medicines you can take and when you can take them.\u00a0If you are not sure, ask your doctor or\u00a0pharmacist\u00a0if any of your medicines are\u00a0NSAIDs.<\/p>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, breastfeeding, and fertility<\/h2>\n\n\n\n<p>Pregnancy&nbsp;<\/p>\n\n\n\n<p>If you are pregnant, think you may be pregnant, or are planning to have a baby, tell your doctor.\u00a0Treatment with Pemetrexed Fresenius Kabi should be avoided during pregnancy.\u00a0Your doctor will discuss any possible risks when Pemetrexed Fresenius Kabi is given during pregnancy.\u00a0Women should use effective contraception during treatment with Pemetrexed Fresenius Kabi.<\/p>\n\n\n\n<p>Breast-feeding&nbsp;<\/p>\n\n\n\n<p>Tell your doctor if you are breastfeeding.<\/p>\n\n\n\n<p>Breast-feeding should be discontinued during treatment with Pemetrexed Fresenius Kabi.<\/p>\n\n\n\n<p>Fertility<\/p>\n\n\n\n<p>Men are advised not to have children during and up to 6 months after treatment with Pemetrexed Fresenius Kabi and should therefore use an effective method of contraception during treatment with Pemetrexed Fresenius Kabi and for up to 6 months after stopping treatment.\u00a0If you plan to have children during treatment or the following 6 months after treatment, consult your doctor or\u00a0pharmacist.\u00a0You may want to seek advice on sperm preservation before starting treatment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Treatment with Pemetrexed Fresenius Kabi may make you feel tired.&nbsp;Be careful when driving or using machines.<\/p>\n\n\n\n<p>Pemetrexed Fresenius Kabi contains 964 mg hydroxypropylbetadex per 100 mg pemetrexed.<\/p>\n\n\n\n<p>If you have any kidney disease, talk to your doctor before using this medicine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to use Pemetrexed Fresenius Kabi<\/h2>\n\n\n\n<p>Pemetrexed Fresenius Kabi is given in a\u00a0dose\u00a0of 500 mg per square meter of body surface area.\u00a0Your height and weight are used to calculate the body surface area.\u00a0Your doctor will use the measurement of your body surface area to calculate the correct\u00a0dose\u00a0for you.\u00a0This\u00a0dose\u00a0can be adjusted or the treatment can be postponed depending on blood levels and your general condition.\u00a0A hospital pharmacist, nurse, or doctor will have mixed Pemetrexed Fresenius Kabi with sodium chloride 9 mg\/ml (0.9%)\u00a0solution for injection\u00a0or 5%\u00a0glucose\u00a0intravenous\u00a0infusion solution before it is given to you.<\/p>\n\n\n\n<p>Pemetrexed Fresenius Kabi is always given as\u00a0an infusion\u00a0to a friend.\u00a0Infusion\u00a0one lasts for about 10 minutes.<\/p>\n\n\n\n<p>When Pemetrexed Fresenius Kabi is given in combination with cisplatin:<\/p>\n\n\n\n<p>Your doctor or hospital pharmacist will have calculated the required&nbsp;dose&nbsp;using your height and weight.&nbsp;Cisplatin is also given as&nbsp;an infusion&nbsp;into a vein and it is given about 30 minutes after&nbsp;infusion&nbsp;one of the Pemetrexed Fresenius Kabi is ready.&nbsp;Infusion&nbsp;one of cisplatin lasts for about 2 hours.<\/p>\n\n\n\n<p>You usually receive&nbsp;an infusion&nbsp;once every three weeks.<\/p>\n\n\n\n<p>Other medicines:<\/p>\n\n\n\n<p>Corticosteroids: Your doctor will prescribe steroid tablets (equivalent to 4 milligrams of <a href=\"https:\/\/zeepedia.com\/medical\/medicines\/toflacort\/\">dexamethasone<\/a> twice daily).\u00a0You should take these tablets the day before, on the day of treatment, and the day after treatment with Pemetrexed Fresenius Kabi.\u00a0The tablets are given to reduce the frequency and severity of the skin reactions that may occur during cancer treatment.<\/p>\n\n\n\n<p>Vitamin supplement: Your doctor will prescribe a\u00a0preparation\u00a0of\u00a0<a href=\"https:\/\/zeepedia.com\/medical\/medicines\/triobe\/\">folic acid<\/a>\u00a0(\u00a0vitamin\u00a0) to be taken by mouth or a multivitamin preparation containing\u00a0folic acid\u00a0(350 to 1000 micrograms) that you should take once a day during treatment with Pemetrexed Fresenius Kabi.\u00a0You should take at least 5\u00a0doses\u00a0during the seven days preceding the first\u00a0dose\u00a0of one of Pemetrexed Fresenius Kabi.\u00a0You should continue to take\u00a0folic acid\u00a0for 21 days after the last Pemetrexed Fresenius\u00a0Kabidos.\u00a0You will also receive\u00a0a\u00a0vitamin\u00a0B\u00a012\u00a0injection\u00a0of 1000 micrograms) the week before Pemetrexed Fresenius Kabi-\u00a0infusion one and then approximately every 9 weeks (equivalent to 3 courses of treatment with Pemetrexed Fresenius Kabi).\u00a0Vitamin\u00a0B\u00a0<sub>12<\/sub>\u00a0and\u00a0folic acid\u00a0are given to reduce the possible harmful effects of cancer treatment.<\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p>You should contact your doctor immediately if you notice any of the following side effects:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Fever or\u00a0infection\u00a0(common): if you have a temperature of 38 \u00b0 C or more, sweating, or other signs of an\u00a0infection\u00a0(because you may have lower than normal white blood cell count, which is very common).\u00a0Infection\u00a0one (blood poisoning) can be serious and lead to death.<\/li><li>If you start to feel chest pain (common) or have a fast heart rate (less common).<\/li><li>If you feel pain,\u00a0redness, swelling, or soreness in your mouth (very common).<\/li><li>Allergic reaction: if you get a rash (very common) \/ burning or stinging sensation (common) or fever (common).\u00a0Skin reactions can be serious and lead to death (rare).\u00a0Contact your doctor if you get a lot of rash,\u00a0itching,\u00a0or blisters (\u00a0Stevens-Johnson\u00a0syndrome or\u00a0toxic epidermal necrolysis\u00a0).<\/li><li>If you get tired, feel weak, get short of breath easily, or if you look pale (because you may have less\u00a0hemoglobin\u00a0than normal, which is very common).<\/li><li>If it bleeds from the gums, nose, or mouth or you get any bleeding that does not want to stop, reddish or pinkish urine, unexpected bruising (because you may have fewer\u00a0platelets\u00a0than normal, which is very common).<\/li><li>If you experience sudden shortness of breath, intense chest pain, or cough with bloody cough (less common) (may indicate a blockage in the blood vessels of the lungs)<\/li><\/ul>\n\n\n\n<p>Other&nbsp;side effects&nbsp;of pemetrexed may occur:<\/p>\n\n\n\n<p><em>Very common (may affect more than 1 user in 10)<\/em><\/p>\n\n\n\n<p>Infection<\/p>\n\n\n\n<p>Sore throat<\/p>\n\n\n\n<p>Low&nbsp;neutrophil count&nbsp;(&nbsp;white blood cell&nbsp;type )<\/p>\n\n\n\n<p>Low&nbsp;white blood cell count<\/p>\n\n\n\n<p>Low hemoglobin (&nbsp;anemia&nbsp;)<\/p>\n\n\n\n<p>Pain,\u00a0redness, swelling, or soreness in the mouth<\/p>\n\n\n\n<p>Decreased appetite<\/p>\n\n\n\n<p>Vomiting<\/p>\n\n\n\n<p>Diarrhea<\/p>\n\n\n\n<p>Nausea<\/p>\n\n\n\n<p>Rash<\/p>\n\n\n\n<p>Flaking skin<\/p>\n\n\n\n<p>Abnormal blood counts showing&nbsp;reduced&nbsp;kidney function<\/p>\n\n\n\n<p>Fatigue (fatigue)<\/p>\n\n\n\n<p><em>Common (may affect up to 1 in 10 people)<\/em><\/p>\n\n\n\n<p>Blood infection<\/p>\n\n\n\n<p>Fever with low&nbsp;neutrophil count&nbsp;(&nbsp;white blood cell&nbsp;type )<\/p>\n\n\n\n<p>Reduced&nbsp;platelet count<\/p>\n\n\n\n<p>Allergic reaction<\/p>\n\n\n\n<p>Dehydration<\/p>\n\n\n\n<p>Taste changes<\/p>\n\n\n\n<p>Muscle weakness due to damage to motor nerves, especially in the arms and legs<\/p>\n\n\n\n<p>Loss of sensation, burning pain, and unsteady gait due to damage to sensory nerves<\/p>\n\n\n\n<p>Dizziness<\/p>\n\n\n\n<p>Inflammation&nbsp;or swelling of the conjunctiva (&nbsp;membrane&nbsp;at the end of the eyelids and covering the eyes white)<\/p>\n\n\n\n<p>Dry eyes<\/p>\n\n\n\n<p>Tear-filled eyes<\/p>\n\n\n\n<p>Dried&nbsp;conjunctiva&nbsp;(&nbsp;membrane&nbsp;on the outer part of the eyelids and covering the eyes white and&nbsp;cornea&nbsp;(the clear layer that protects the&nbsp;iris&nbsp;and&nbsp;pupil&nbsp;)<\/p>\n\n\n\n<p>Swollen eyelids<\/p>\n\n\n\n<p>Eye problems, such as dryness, tearing, irritation, and\/or pain.<\/p>\n\n\n\n<p>Heart failure&nbsp;(a condition that affects the pumping power of your heart muscle)<\/p>\n\n\n\n<p>Irregular heartbeat<\/p>\n\n\n\n<p>Indigestion<\/p>\n\n\n\n<p>Constipation<\/p>\n\n\n\n<p>Abdominal pain<\/p>\n\n\n\n<p>Liver: increase in the substances in the blood produced by the liver<\/p>\n\n\n\n<p>Increased skin pigmentation<\/p>\n\n\n\n<p>Itching<\/p>\n\n\n\n<p>Rash on the body therewith red marks<\/p>\n\n\n\n<p>Hair loss<\/p>\n\n\n\n<p>Hives<\/p>\n\n\n\n<p>Kidney failure<\/p>\n\n\n\n<p>Decreased renal function<\/p>\n\n\n\n<p>Fever<\/p>\n\n\n\n<p>Pain<\/p>\n\n\n\n<p>Excess fluid in body tissue, which causes swelling<\/p>\n\n\n\n<p>Chest pain<\/p>\n\n\n\n<p>Inflammation&nbsp;and ulceration of the mucous membranes that line the digestive tract<\/p>\n\n\n\n<p><em>Uncommon (may affect up to 1 in 100 people)<\/em><\/p>\n\n\n\n<p>Reduction in the number of red and&nbsp;white blood cells&nbsp;and&nbsp;platelets<\/p>\n\n\n\n<p>Stroke<\/p>\n\n\n\n<p>Type of&nbsp;stroke&nbsp;when an&nbsp;artery&nbsp;to the brain is blocked<\/p>\n\n\n\n<p>Bleeding inside the skull<\/p>\n\n\n\n<p>Angina (Chest pain caused by decreased blood flow to the heart)<\/p>\n\n\n\n<p>Myocardial infarction<\/p>\n\n\n\n<p>Narrowing or blockage of the coronary arteries<\/p>\n\n\n\n<p>Faster heart rate<\/p>\n\n\n\n<p>Reduced blood distribution to the limbs<\/p>\n\n\n\n<p>Blood clots in the pulmonary blood vessels (&nbsp;pulmonary embolism&nbsp;)<\/p>\n\n\n\n<p>Inflammation&nbsp;and scarring of the lungs with respiratory problems<\/p>\n\n\n\n<p>Passage of bright red blood from the anus<\/p>\n\n\n\n<p>Bleeding in the gastrointestinal tract<\/p>\n\n\n\n<p>Broken intestine<\/p>\n\n\n\n<p>Inflammation&nbsp;of the esophageal&nbsp;mucosa&nbsp;(esophagus)<\/p>\n\n\n\n<p>Colitis&nbsp;(&nbsp;inflammation&nbsp;of the wall of the colon, which may be accompanied by bleeding from the intestines or&nbsp;rectum&nbsp;(seen only in combination with cisplatin)<\/p>\n\n\n\n<p>Inflammation,\u00a0edema\u00a0,\u00a0erythema,\u00a0and\u00a0erosion\u00a0of the mucosal surface of the esophagus caused by radiation therapy<\/p>\n\n\n\n<p>Inflammation&nbsp;of the lung caused by radiation therapy<\/p>\n\n\n\n<p><em>Rare (may affect up to 1 in 1,000 people)<\/em><\/p>\n\n\n\n<p>Destruction of&nbsp;red blood cells<\/p>\n\n\n\n<p>Anaphylactic&nbsp;shock&nbsp;(severe&nbsp;allergic reaction&nbsp;)<\/p>\n\n\n\n<p>Inflammatory conditions of the liver<\/p>\n\n\n\n<p>Redness of the skin<\/p>\n\n\n\n<p>Skin rash that may occur on skin that has previously been exposed to radiation therapy.<\/p>\n\n\n\n<p><em>Very rare (may affect up to 1 in 10,000 people)<\/em><\/p>\n\n\n\n<p>Infection&nbsp;of skin and soft tissue<\/p>\n\n\n\n<p>Stevens-Johnson syndrome (a type of severe reaction to skin and mucous membranes that can be life-threatening)<\/p>\n\n\n\n<p>Toxic epidermal necrolysis&nbsp;(a type of severe skin reaction that can be life-threatening)<\/p>\n\n\n\n<p>An autoimmune\u00a0condition that results in skin rashes and blisters on legs, arms, and abdomen<\/p>\n\n\n\n<p>Inflammation&nbsp;of the skin characterized by the presence of bullous conditions with fluid-filled blistering)<\/p>\n\n\n\n<p>Fragile skin, blisters, and\u00a0erosion\u00a0as well as scarring of the skin<\/p>\n\n\n\n<p>Redness, pain, and swelling mainly in the lower legs<\/p>\n\n\n\n<p>Inflammation&nbsp;of the skin and fat under the skin (pseudocellulitis)<\/p>\n\n\n\n<p>Inflammation&nbsp;of the skin (&nbsp;dermatitis&nbsp;)<\/p>\n\n\n\n<p>Skin that becomes inflamed, itchy, red, cracked, and rough<\/p>\n\n\n\n<p>Intense itchy spots<\/p>\n\n\n\n<p><em>Has been reported (occurs in an unknown number of users)<\/em><\/p>\n\n\n\n<p>A form of&nbsp;diabetes&nbsp;that is primarily based on kidney&nbsp;pathology<\/p>\n\n\n\n<p>Kidney disorder involving tubular epithelial cells (which form renal tubules) death<\/p>\n\n\n\n<p>You may get any of these symptoms and\/or ailments.\u00a0If you start to experience any of these\u00a0side effects, talk to your doctor as soon as possible.<\/p>\n\n\n\n<p>If you have any\u00a0side effects, talk to your doctor.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Pemetrexed Fresenius Kabi<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the vial label and the carton after \u201cEXP.\u00a0that \u201d.\u00a0The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>Do not store above 25 \u00b0 C.<\/p>\n\n\n\n<p>Keep the vial in the outer carton.&nbsp;Sensitive to light.<\/p>\n\n\n\n<p>Infusion solution: The medicine should be used immediately.&nbsp;If the preparation instructions are followed, chemical and physical durability has been demonstrated for 21 days in the refrigerator and 7 days in<\/p>\n\n\n\n<p>25 \u00b0 C for diluted pemetrexed infusion solution.<\/p>\n\n\n\n<p>The solution should not be used if it contains particles.<\/p>\n\n\n\n<p>This medicine is for single use only.<\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the pack and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<p>The active substance is pemetrexed.<\/p>\n\n\n\n<p>One ml of concentrate contains 25 mg of pemetrexed.<\/p>\n\n\n\n<p>After dilution, a\u00a0vial\u00a0of 4 ml concentrate contains 100 mg of pemetrexed (as pemetrexed acid).<\/p>\n\n\n\n<p>After dilution, a\u00a0vial\u00a0of 20 ml concentrate contains 500 mg of pemetrexed (as pemetrexed acid).<\/p>\n\n\n\n<p>After dilution, a\u00a0vial\u00a0of 40 ml concentrate contains 1000 mg of pemetrexed (as pemetrexed acid).<\/p>\n\n\n\n<p>The other ingredients are hydroxypropyl betadex,\u00a0hydrochloric acid, <a href=\"https:\/\/zeepedia.com\/medical\/medicines\/tribonate\/\">trometamol<\/a>, and water for injections.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>Pemetrexed Fresenius Kabi is a concentrate for solution for\u00a0infusion\u00a0(sterile concentrate) packaged in a\u00a0glass\u00a0vial.\u00a0It is colorless to the slightly yellowish or greenish-yellow solution.<\/p>\n\n\n\n<p>Available in packs of 1\u00a0vial.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p><strong>Marketing Authorisation Holder<\/strong><\/p>\n\n\n\n<p>Fresenius Kabi Deutschland GmbH<\/p>\n\n\n\n<p>Else \u2011 Kr\u00f6ner \u2011 Stra\u00dfe 1.61352 Bad Homburg vdH\u00f6he<\/p>\n\n\n\n<p>Germany<\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>Fresenius Kabi Deutschland GmbH<\/p>\n\n\n\n<p>Pfingstweide 53 61169 Friedberg<\/p>\n\n\n\n<p>Germany<\/p>\n\n\n\n<p>Or<\/p>\n\n\n\n<p>Fresenius Kabi Polska Sp.&nbsp;z oo<\/p>\n\n\n\n<p>ul.&nbsp;Sienkiewicza 25, Kutno, 99-300, Poland<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Pemetrexed Fresenius Kabi is co-administered with cisplatin, another anti-cancer drug, for the treatment of malignant pleural mesothelioma, a form of lung sac cancer, in patients who have not previously received anti-cancer drug therapy.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,18527],"tags":[21095,21130,10012,21126,21129,10015,10013,21127,21128,10014],"class_list":["post-20675","post","type-post","status-publish","format-standard","hentry","category-medicines","category-p","tag-benefits-of-pemetrexed","tag-benefits-of-pemetrexed-fresenius-kabi","tag-pemetrexed","tag-pemetrexed-fresenius-kabi","tag-pemetrexed-fresenius-kabi-side-effects","tag-pemetrexed-side-effects","tag-what-is-pemetrexed","tag-what-is-pemetrexed-fresenius-kabi","tag-what-pemetrexed-fresenius-kabi-is-used-for","tag-what-pemetrexed-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/20675","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=20675"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/20675\/revisions"}],"predecessor-version":[{"id":20732,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/20675\/revisions\/20732"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=20675"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=20675"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=20675"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}