{"id":20621,"date":"2022-04-07T10:46:57","date_gmt":"2022-04-07T10:46:57","guid":{"rendered":"https:\/\/zeepedia.com\/?p=20621"},"modified":"2022-04-08T11:15:32","modified_gmt":"2022-04-08T11:15:32","slug":"pemetrexed-reig-jofre","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/pemetrexed-reig-jofre\/","title":{"rendered":"Pemetrexed Reig Jofre &#8211; Pemetrexed uses, dose and side effects"},"content":{"rendered":"\n<p>100 mg and 500 mg&nbsp;powder for concentrate for&nbsp;solution for&nbsp;infusion<br>pemetrexed<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Pemetrexed Reig Jofre is and what it is used for<\/h2>\n\n\n\n<p>Pemetrexed Reig Jofre is a medicine used to treat cancer.<\/p>\n\n\n\n<p>Pemetrexed Reig Jofre is co-administered with cisplatin, another anti-cancer drug, for the treatment of malignant pleural mesothelioma, a form of lung sac cancer, in patients who have not previously received anti-cancer drug therapy.<\/p>\n\n\n\n<p>Pemetrexed Reig Jofre is also used with cisplatin in the initial treatment of advanced lung cancer.<\/p>\n\n\n\n<p>Pemetrexed Reig Jofre can be prescribed to you if you have advanced lung cancer and your disease has responded to treatment or if it is largely unchanged after initial drug treatment.<\/p>\n\n\n\n<p>In addition, Pemetrexed Reig Jofre is used to treat advanced lung cancer whose disease has progressed, after other previous drug treatments have been used.<\/p>\n\n\n\n<p>Pemetrexed contained in Pemetrexed Reig Jofre may also be approved for the treatment of other conditions not mentioned in this product information.\u00a0Ask your doctor, pharmacist, or another healthcare professional if you have any further questions, and always follow their instructions.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before using Pemetrexed Reig Jofre<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Pemetrexed Reig Jofre<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic (hypersensitive) to pemetrexed or any of the other ingredients of Pemetrexed Reig Jofre (listed in section 6).<\/li><li>if you are breastfeeding.\u00a0You should stop breastfeeding during treatment with Pemetrexed Reig Jofre.<\/li><li>if you have recently been vaccinated or are just about to be vaccinated against yellow fever.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before receiving Pemetrexed Reig Jofre.<\/p>\n\n\n\n<p>Talk to your doctor or pharmacist if you have or have had kidney problems, as you may not be able to get Pemetrexed Reig Jofre.<\/p>\n\n\n\n<p>Before each\u00a0infusion, blood samples will be taken to determine if the function of the kidneys and liver is sufficient and to check that the amount of\u00a0blood cells\u00a0is sufficient to obtain Pemetrexed Reig Jofre.\u00a0Your doctor may choose to change the\u00a0dose\u00a0or postpone your treatment depending on your general condition and if your blood levels are too low.\u00a0If you are also taking cisplatin, your doctor will make sure that you have been given enough fluids and that you will receive appropriate treatment before and after the cisplatin treatment to prevent vomiting.<\/p>\n\n\n\n<p>If you have received radiation therapy or if such treatment is planned, tell your doctor, like radiation therapy and Pemetrexed Reig Jofre may cause immediate or late\u00a0side effects.<\/p>\n\n\n\n<p>If you have recently been vaccinated, you should tell your doctor, as Pemetrexed Reig Jofre in connection with vaccination may cause unwanted reactions.<\/p>\n\n\n\n<p>Tell your doctor if you have, or have previously had, heart disease.<\/p>\n\n\n\n<p>If you have fluid accumulation around your lungs, your doctor may decide to remove the fluid before treatment with Pemetrexed Reig Jofre.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children and young people<\/h2>\n\n\n\n<p>There is no relevant use of Pemetrexed Reig Jofre in children and adolescents.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Pemtrexed Reig Jofre<\/h2>\n\n\n\n<p>Tell your doctor if you are taking any medicine for pain or\u00a0inflammation\u00a0(swelling), such as so-called non-steroidal anti-inflammatory drugs (\u00a0NSAIDs\u00a0), including over-the-counter medicines (such as\u00a0ibuprofen\u00a0).\u00a0There are many different types of these drugs with varying duration of action.\u00a0Knowing the date of the planned\u00a0infusion\u00a0of Pemetrexed Reig Jofre and\/or your renal function status, your doctor must advise you on which medicines you can take and when you can take them.\u00a0If you are not sure, ask your doctor or\u00a0pharmacist\u00a0if any of your medicines are\u00a0NSAIDs.<\/p>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, breastfeeding, and fertility<\/h2>\n\n\n\n<p><strong>Pregnancy<\/strong><\/p>\n\n\n\n<p>If you are pregnant or planning to become pregnant or think you may be pregnant,&nbsp;<strong>tell your doctor.&nbsp;<\/strong>Treatment with Pemetrexed Reig Jofre should be avoided during pregnancy.&nbsp;Your doctor will discuss any possible risks of Pemetrexed Reig Jofre during pregnancy.&nbsp;Women should use effective contraception during treatment with Pemetrexed Reig Jofre.<\/p>\n\n\n\n<p><strong>Breast-feeding<\/strong><\/p>\n\n\n\n<p>Tell your doctor if you are breastfeeding.\u00a0Breast-feeding should be discontinued during treatment with Pemetrexed Reig Jofre.<\/p>\n\n\n\n<p><strong>Fertility<\/strong><\/p>\n\n\n\n<p>Men are advised not to have children during and up to 6 months after Pemetrexed Reig Jofre treatment and should therefore use an effective method of contraception during Pemetrexed Reig Jofre treatment and up to 6 months after stopping treatment.\u00a0If you plan to have children during treatment or the following 6 months after treatment, consult your doctor or\u00a0pharmacist.\u00a0You may want to seek advice on sperm preservation before starting treatment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Treatment with Pemetrexed Reig Jofre may make you feel tired.&nbsp;Be careful when driving or using machines.<\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects.\u00a0Descriptions of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to use Pemetrexed Reig Jofre<\/h2>\n\n\n\n<p>Pemetrexed Reig Jofre is given in a\u00a0dose\u00a0of 500 mg per square meter of body surface area.\u00a0Your height and weight are used to calculate the body surface area.\u00a0Your doctor will use the measurement of your body surface area to calculate the correct\u00a0dose\u00a0for you.\u00a0This\u00a0dose\u00a0can be adjusted or the treatment can be postponed depending on blood levels and your general condition.\u00a0A hospital pharmacist, nurse, or doctor will have mixed the Pemetrexed Reig Jofre powder in\u00a0a sterile\u00a09 mg\/ml (0.9%) sodium chloride solution before giving it to you.<\/p>\n\n\n\n<p>Pemetrexed Reig Jofre is always given as&nbsp;an infusion&nbsp;in a friend.&nbsp;Infusion&nbsp;one lasts for about 10 minutes.<\/p>\n\n\n\n<p>Then Pemetrexed Reig Jofre is given in combination with cisplatin: Your doctor or hospital pharmacist will have calculated the required&nbsp;dose&nbsp;using your height and weight.&nbsp;Cisplatin is also given as&nbsp;an infusion&nbsp;into a vein and is given approximately 30 minutes after the end of the Pemetrexed Reig Jofre infusion.&nbsp;Infusion&nbsp;one of cisplatin lasts for about 2 hours.<\/p>\n\n\n\n<p>You usually receive&nbsp;an infusion&nbsp;once every three weeks.<\/p>\n\n\n\n<p>Other medicines:<\/p>\n\n\n\n<p>Corticosteroids: Your doctor will prescribe steroid tablets (equivalent to 4 milligrams of <a href=\"https:\/\/zeepedia.com\/medical\/medicines\/toflacort\/\">dexamethasone<\/a> twice daily).\u00a0You should take these tablets the day before, on the day of treatment, and the day after treatment with Pemetrexed Reig Jofre.\u00a0The tablets are given to reduce the frequency and severity of the skin reactions that may occur during cancer treatment.<\/p>\n\n\n\n<p>Vitamin supplement: Your doctor will prescribe a\u00a0preparation\u00a0of\u00a0<a href=\"https:\/\/zeepedia.com\/medical\/medicines\/triobe\/\">folic acid<\/a>\u00a0(\u00a0vitamin\u00a0) to be taken by mouth or a multivitamin preparation containing\u00a0folic acid\u00a0(350 to 1000 micrograms) that you should take once a day during treatment with Pemetrexed Reig Jofre.\u00a0You should take at least 5\u00a0doses\u00a0during the seven days before the first\u00a0dose\u00a0of one of Pemetrexed Reig Jofre.\u00a0You should continue to take\u00a0folic acid\u00a0for 21 days after the last Pemetrexed Reig\u00a0Jofredos.\u00a0You will also receive a\u00a0vitamin\u00a0B12\u00a0injection\u00a0(1000 micrograms) the week before the Pemetrexed Reig Jofre\u00a0infusion .one and then approximately every 9 weeks (equivalent to 3 courses of treatment with Pemetrexed Reig Jofre).\u00a0Vitamin\u00a0B12 and\u00a0folic acid\u00a0are given to reduce the potentially harmful effects of cancer treatment.<\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you take more Pemetrexed Reig Jofre than you should<\/h2>\n\n\n\n<p>You will be given this medicine in a hospital and it is unlikely that you will get too much.&nbsp;If you are worried that you have been given too high a&nbsp;dose&nbsp;or if you have any questions about the&nbsp;dose&nbsp;you have been given, talk to your doctor or nurse who will give you the medicine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p>You should contact your doctor immediately if you notice any of the following side effects:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Fever or\u00a0infection\u00a0(common): if you have a temperature of38 \u00b0 C or more, sweating, or other signs of an\u00a0infection\u00a0(as you may have a lower\u00a0than normal\u00a0white blood cell count, which is very common).\u00a0Infection\u00a0one (blood poisoning) can be serious and lead to death.<\/li><li>If you start to feel chest pain (common) or have a fast heart rate (less common).<\/li><li>If you feel pain,\u00a0redness, swelling, or soreness in your mouth (very common).<\/li><li>Allergic reaction: if you get a rash (very common) \/ burning or stinging sensation (common) or fever (common).\u00a0Skin reactions can be serious and lead to death (rare).\u00a0Contact your doctor if you get a lot of rash,\u00a0itching,\u00a0or blisters (\u00a0Stevens-Johnson\u00a0syndrome or\u00a0toxic epidermal necrolysis\u00a0).<\/li><li>If you get tired, feel weak, get short of breath easily, or if you look pale (because you may have less hemoglobin than normal, which is very common).<\/li><li>If there is bleeding from the gums, nose, or mouth or you get any bleeding that does not want to stop, reddish or pinkish urine, unexpected bruising (because you may have fewer\u00a0platelets\u00a0than normal, which is very common).<\/li><li>If you experience sudden shortness of breath, intense chest pain, or cough with bloody cough (less common) (may indicate a blockage in the blood vessels of the lungs)<\/li><\/ul>\n\n\n\n<p>The frequency of possible&nbsp;side effects&nbsp;is defined below as follows:<\/p>\n\n\n\n<p>Very common (may affect more than 1 patient in 10)<\/p>\n\n\n\n<p>Common (may affect 1 to 10 patients in 100)<\/p>\n\n\n\n<p>Uncommon (may affect 1 to 10 patients in 1,000)<\/p>\n\n\n\n<p>Rare (may affect 1 to 10 patients in 10,000)<\/p>\n\n\n\n<p>Very rare (may affect less than 1 patient in 10,000).<\/p>\n\n\n\n<p>Other&nbsp;side effects&nbsp;of Pemetrexed Reig Jofre that may occur:<\/p>\n\n\n\n<p><em>Very common<\/em><\/p>\n\n\n\n<p>Decreased&nbsp;white blood cell count<\/p>\n\n\n\n<p>Low hemoglobin (&nbsp;anemia&nbsp;)<\/p>\n\n\n\n<p>Reduced&nbsp;platelet count<\/p>\n\n\n\n<p>Diarrhea<\/p>\n\n\n\n<p>Vomiting<\/p>\n\n\n\n<p>Pain,\u00a0redness\u00a0 swelling, or soreness in the mouth<\/p>\n\n\n\n<p>Nausea<\/p>\n\n\n\n<p>Decreased appetite<\/p>\n\n\n\n<p>Fatigue (fatigue)<\/p>\n\n\n\n<p>Rash<\/p>\n\n\n\n<p>Hair loss<\/p>\n\n\n\n<p>Constipation<\/p>\n\n\n\n<p>Loss of feeling<\/p>\n\n\n\n<p>Kidneys: abnormal blood counts<\/p>\n\n\n\n<p><em>Usual<\/em><\/p>\n\n\n\n<p>Allergic reaction: skin rash\/burning or stinging sensation<\/p>\n\n\n\n<p>Infection&nbsp;(including sepsis)<\/p>\n\n\n\n<p>Fever<\/p>\n\n\n\n<p>Dehydration<\/p>\n\n\n\n<p>Kidney failure<\/p>\n\n\n\n<p>Skin irritation and&nbsp;itching<\/p>\n\n\n\n<p>Chest pain<\/p>\n\n\n\n<p>Muscle weakness<\/p>\n\n\n\n<p>Conjunctivitis&nbsp;(inflamed eye)<\/p>\n\n\n\n<p>Troublesome stomach<\/p>\n\n\n\n<p>Abdominal pain<\/p>\n\n\n\n<p>Taste changes<\/p>\n\n\n\n<p>Liver: abnormal blood counts<\/p>\n\n\n\n<p>Tear-filled eyes<\/p>\n\n\n\n<p>Increased skin pigmentation<\/p>\n\n\n\n<p><em>Less common<\/em><\/p>\n\n\n\n<p>Acute&nbsp;renal failure<\/p>\n\n\n\n<p>Fast heart rate<\/p>\n\n\n\n<p>Inflammation&nbsp;of the esophageal&nbsp;mucosa&nbsp;(esophagus) has occurred with Pemetrexed Reig Jofre and radiation therapy<\/p>\n\n\n\n<p>Colitis&nbsp;(&nbsp;inflammation&nbsp;of the wall of the colon, which may be accompanied by bleeding from the intestines)<\/p>\n\n\n\n<p>Interstitial&nbsp;pneumonitis&nbsp;(scarring of the lungs)<\/p>\n\n\n\n<p>Edema&nbsp;(accumulation of fluid in any body tissue that causes swelling).<\/p>\n\n\n\n<p>Some patients have had a heart attack,\u00a0stroke,\u00a0or &#8220;mini-stroke&#8221; during treatment with Pemetrexed Reig Jofre, usually in combination with other cancer treatments.<\/p>\n\n\n\n<p>Pancytopenia &#8211; combined low number of\u00a0white blood cells,\u00a0red blood cells,\u00a0and\u00a0platelets<\/p>\n\n\n\n<p>Radiation pneumonitis (scarring of the air bubbles in connection with radiation therapy) can occur in patients who have also received radiation therapy either before, during, or after treatment with Pemetrexed Reig Jofre.\u00a0Pain and low temperature in arms or legs with discoloration have been reported.\u00a0Blood clots in the pulmonary blood vessels (\u00a0pulmonary embolism\u00a0)<\/p>\n\n\n\n<p><em>Rare<\/em><\/p>\n\n\n\n<p>Skin rash, which looks like severe sun damage, can occur on skin that has previously (several days or years ago) been subjected to radiation treatment.<\/p>\n\n\n\n<p>Bullous conditions (skin diseases with blistering) including&nbsp;Stevens-Johnson&nbsp;syndrome and&nbsp;toxic epidermal necrolysis<\/p>\n\n\n\n<p>Hemolytic anemia&nbsp;(&nbsp;anemia&nbsp;caused by the destruction of the red&nbsp;blood cells&nbsp;)<\/p>\n\n\n\n<p>Hepatitis&nbsp;(hepatitis)<\/p>\n\n\n\n<p>Anaphylactic&nbsp;shock&nbsp;(severe&nbsp;allergic reaction&nbsp;)<\/p>\n\n\n\n<p><em>No known frequency: can not be calculated from the available data<\/em><\/p>\n\n\n\n<p>Increased urine output<\/p>\n\n\n\n<p>Thirst and increased water intake<\/p>\n\n\n\n<p>Hypernatremia&nbsp;&#8211; increased sodium content in the blood<\/p>\n\n\n\n<p>Inflammation of the skin, primarily the lower\u00a0extremity\u00a0with swelling, pain, and\u00a0redness<\/p>\n\n\n\n<p>You may get any of these symptoms and\/or ailments.\u00a0If you start to experience any of these\u00a0side effects, talk to your doctor as soon as possible.<\/p>\n\n\n\n<p>If you have any\u00a0side effects, talk to your doctor.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Pemetrexed Reig Jofre<\/h2>\n\n\n\n<p>Keep out of sight and reach of children.<\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the carton.<\/p>\n\n\n\n<p>This medicine has no special storage instructions.<\/p>\n\n\n\n<p>Dissolved drug and infusion solution: The drug should be used immediately.\u00a0Chemical and physical shelf life for 24 hours in a refrigerator or 25 \u00b0 C has been demonstrated for the reconstituted\u00a0stock solution\u00a0and the infusion solution of pemetrexed if\u00a0reconstituted\u00a0according to the instructions.<\/p>\n\n\n\n<p>This medicine is for single use only.\u00a0Any unused solution should be disposed of to local requirements.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the pack and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<p>The active substance is pemetrexed.<\/p>\n\n\n\n<p>Pemetrexed Reig Jofre 100 mg: One&nbsp;vial&nbsp;contains 100 mg of pemetrexed (as disodium pemetrexed 2.5 H&nbsp;<sub>2<\/sub>&nbsp;O).<\/p>\n\n\n\n<p>Pemetrexed Reig Jofre 500 mg: One&nbsp;vial&nbsp;contains 500 mg pemetrexed (as disodium pemetrexed 2.5 H&nbsp;<sub>2<\/sub>&nbsp;O).<\/p>\n\n\n\n<p>After reconstitution, the solution contains 25 mg \/ ml pemetrexed.\u00a0Further dilution of healthcare professionals is required before\u00a0injection.<\/p>\n\n\n\n<p>The other ingredients are mannitol,\u00a0hydrochloric acid\u00a0(for\u00a0pH\u00a0adjustment), and sodium hydroxide (for\u00a0pH\u00a0adjustment).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>Pemetrexed Reig Jofre is a powder for concentrate for solution for\u00a0infusion\u00a0in a\u00a0vial.\u00a0It is a white to light yellow or greenish-yellow, freeze-dried powder.<\/p>\n\n\n\n<p>The package contains a\u00a0vial.<\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p>Marketing Authorisation Holder:<\/p>\n\n\n\n<p>Laboratory Reig Jofre SA<\/p>\n\n\n\n<p>Grand Captain, 10<\/p>\n\n\n\n<p>08970 Sant Joan Desp\u00ed (Barcelona)<\/p>\n\n\n\n<p>Spain<\/p>\n\n\n\n<p>Local representative:<\/p>\n\n\n\n<p>Bioglan AB<\/p>\n\n\n\n<p>Box 50310<\/p>\n\n\n\n<p>202 13 Malm\u00f6<\/p>\n\n\n\n<p>Manufacturer:<\/p>\n\n\n\n<p>Laboratory Reig Jofre SA<\/p>\n\n\n\n<p>Jarama 111, Poligono Industrial<\/p>\n\n\n\n<p>45007 Toledo<\/p>\n\n\n\n<p>Spain<\/p>\n\n\n\n<p>This medicinal product is authorized under the European Economic Area under the names:<\/p>\n\n\n\n<p>Denmark: Pemetrexed Reig Jofre<\/p>\n\n\n\n<p>Iceland: Pemetrexed Reig Jofre 100 mg powder for concentrate for solution for infusion<\/p>\n\n\n\n<p>Pemetrexed Reig Jofre 500 mg concentrate for solution for infusion<\/p>\n\n\n\n<p>Norway: Pemetrexed Reig Jofre<\/p>\n\n\n\n<p>Spanien: Pemetrexed Sala 100 mg powder for concentrate for EFG perfusion solution<\/p>\n\n\n\n<p>Pemetrexed Sala 500 mg powder for concentration for EFG perfusion solution<\/p>\n\n\n\n<p>United Kingdom: Pemetrexed 100 mg powder for concentrate for solution for&nbsp;infusion<\/p>\n\n\n\n<p>Pemetrexed 500 mg powder for concentrate for solution for&nbsp;infusion<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Pemetrexed Reig Jofre is co-administered with cisplatin, another anti-cancer drug, for the treatment of malignant pleural mesothelioma, a form of lung sac cancer, in patients who have not previously received anti-cancer drug therapy.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,18527],"tags":[21095,21105,10012,21101,21104,10015,10013,21102,10014,21103],"class_list":["post-20621","post","type-post","status-publish","format-standard","hentry","category-medicines","category-p","tag-benefits-of-pemetrexed","tag-benefits-of-pemetrexed-reig-jofre","tag-pemetrexed","tag-pemetrexed-reig-jofre","tag-pemetrexed-reig-jofre-side-effects","tag-pemetrexed-side-effects","tag-what-is-pemetrexed","tag-what-is-pemetrexed-reig-jofre","tag-what-pemetrexed-is-used-for","tag-what-pemetrexed-reig-jofre-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/20621","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=20621"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/20621\/revisions"}],"predecessor-version":[{"id":20666,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/20621\/revisions\/20666"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=20621"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=20621"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=20621"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}