{"id":20556,"date":"2022-04-06T11:22:07","date_gmt":"2022-04-06T11:22:07","guid":{"rendered":"https:\/\/zeepedia.com\/?p=20556"},"modified":"2022-04-07T10:05:46","modified_gmt":"2022-04-07T10:05:46","slug":"pazenir","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/pazenir\/","title":{"rendered":"Pazenir &#8211; Paclitaxel uses, dose and side effects"},"content":{"rendered":"\n<p>5 mg \/ ml&nbsp;powder for solution for&nbsp;infusion&nbsp;,&nbsp;dispersion<br>paclitaxel<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Pazenir is and what it is used for<\/h2>\n\n\n\n<p><strong>What Pazenir is<\/strong><\/p>\n\n\n\n<p>The active substance in Pazenir is paclitaxel.&nbsp;Paclitaxel is bound to the human&nbsp;protein&nbsp;et albumin in the form of very small particles called nanoparticles.&nbsp;Paclitaxel belongs to a group of medicines called &#8220;taxanes&#8221; and is used to treat cancer.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Paclitaxel is the part of medicine that affects cancer.\u00a0It works by preventing cancer cells from dividing, which means they die.<\/li><li>Albumin is the part of the drug that helps paclitaxel to dissolve in the blood, pass through the walls of blood vessels, and penetrate the\u00a0tumor.\u00a0This means that other chemical substances that can cause\u00a0side effects\u00a0that can be life-threatening are not needed.\u00a0Such\u00a0side effects\u00a0occur to a much lesser extent with Pazenir.<\/li><\/ul>\n\n\n\n<p><strong>What Pazenir is used for<\/strong><\/p>\n\n\n\n<p>Pazenir is used to treat the following types of cancer:<\/p>\n\n\n\n<p>Breast cancer<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Breast cancer has spread to other parts of the body (this is called &#8220;metastatic&#8221; breast cancer).<\/li><li>Pazenir is used in metastatic breast cancer when at least one other treatment has been tried but has not worked, and when treatments with a group of medicines called &#8216;anthracyclines&#8217; are not appropriate.<\/li><li>People with metastatic breast cancer who received paclitaxel bound to the human\u00a0protein\u00a0et albumin when another treatment did not work had a greater reduction in tumor size and lived longer than people who received another treatment.<\/li><\/ul>\n\n\n\n<p>Pancreatic cancer<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Pazenir is used with a medicine called gemcitabine if you have metastatic pancreatic cancer (pancreatic cancer has spread to other parts of the body).\u00a0People with metastatic pancreatic cancer who received Pazenir with gemcitabine in a\u00a0clinical trial\u00a0lived longer than those who received gemcitabine alone.<\/li><\/ul>\n\n\n\n<p>Lung cancer<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Pazenir is also used with a medicine called carboplatin if you have the most common type of lung cancer, called &#8216;non-small cell lung cancer&#8217;.<\/li><li>Pazenir is used in non-small cell lung cancer\u00a0when\u00a0surgery\u00a0or radiation therapy is not appropriate to treat the disease.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before using Pazenir<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Pazenir<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic (hypersensitive) to paclitaxel or any of the other ingredients of Pazenir (listed in section 6).<\/li><li>if you are breastfeeding.<\/li><li>if you have a low\u00a0white blood cell count\u00a0(neutrophil count &lt;1.5 x 10\u00a0<sup>9<\/sup>\u00a0\/ l before treatment &#8211; your doctor will tell you).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor or nurse before using Pazenir<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you have poor kidney function.<\/li><li>if you have severe liver problems.<\/li><li>if you have heart problems.<\/li><\/ul>\n\n\n\n<p>Talk to your doctor or nurse if you experience any of these symptoms during treatment with Pazenir, as treatment may need to be stopped or a&nbsp;dose&nbsp;reduced:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you get abnormal bruising, bleeding, or signs of\u00a0infection\u00a0such as a sore throat or fever<\/li><li>if you experience numbness, tingling or tingling, are sensitive to touch, or have muscle weakness<\/li><li>if you experience breathing problems, e.g.\u00a0shortness of breath or dry cough.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Children and young people<\/h2>\n\n\n\n<p>This medicine is for adults only and should not be taken by children and adolescents under 18 years of age.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Pazenir<\/h2>\n\n\n\n<p>Tell your doctor if you are taking or have recently taken any other medicines.\u00a0This also applies to over-the-counter ones, including herbal preparations.\u00a0This is because Pazenir may affect the effectiveness of other medicines.\u00a0In addition, other medicines may affect the effect of Pazenir.<\/p>\n\n\n\n<p>Be careful and talk to your doctor while taking Pazenir while taking any of the following:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>medicines to treat your\u00a0infections\u00a0(ie\u00a0antibiotics\u00a0such as erythromycin and rifampicin; ask your doctor, nurse, or pharmacist if you are not sure if the medicine you are taking is an\u00a0antibiotic\u00a0) and medicines to treat fungal infections (eg\u00a0ketoconazole\u00a0)<\/li><li>drugs used to help stabilize your mood, also called antidepressants (eg\u00a0fluoxetine\u00a0)<\/li><li>medicines used to treat seizures (\u00a0epilepsy\u00a0) (eg carbamazepine and\u00a0phenytoin\u00a0)<\/li><li>medicines used to lower blood lipid levels (eg gemfibrozil)<\/li><li>medicines used to treat heartburn or\u00a0stomach ulcers\u00a0(eg cimetidine)<\/li><li>medicines used to treat\u00a0HIV\u00a0and\u00a0AIDS\u00a0(eg ritonavir, saquinavir, indinavir, nelfinavir, efavirenz and nevirapine)<\/li><li>a drug called clopidogrel used to prevent blood clots.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, breastfeeding, and fertility<\/h2>\n\n\n\n<p>Paclitaxel can cause serious birth defects and should therefore not be used if you are pregnant.&nbsp;Your doctor will make sure that you have to leave a pregnancy test before starting treatment with Pazenir.<\/p>\n\n\n\n<p>If you are a woman of\u00a0childbearing potential, you should use effective contraception during and up to one month after being treated with Pazenir.<\/p>\n\n\n\n<p>You should not breastfeed while taking Pazenir as it is unknown if the active substance paclitaxel passes into breast milk.<\/p>\n\n\n\n<p>If you are a man, you should not try to have children during and up to six months after treatment.\u00a0Male patients may also consult sperm preservation before treatment, as treatment with Pazenir may lead to irreversible\u00a0infertility.<\/p>\n\n\n\n<p>Talk to your doctor before taking this medicine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Some people may feel tired or dizzy after receiving Pazenir.&nbsp;If this happens to you, do not drive, use any tools or machines.<\/p>\n\n\n\n<p>If you are taking any other medicines as part of your treatment, you should consult your doctor about driving and using machines.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pazenir contains sodium<\/h2>\n\n\n\n<p>This medicine contains less than 1 mmol (23 mg)\u00a0sodium\u00a0per\u00a0vial, ie essentially &#8216;sodium-free&#8217;.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to use Pazenir<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop using Pazenir<\/h2>\n\n\n\n<p>Pazenir is given to you by a doctor or nurse with an\u00a0intravenous\u00a0drip into a vein.\u00a0The dose\u00a0you receive is based on your body surface area and your blood test results.\u00a0The usual\u00a0dose\u00a0for breast cancer is 260 mg \/ m\u00a0<sup>2<\/sup>\u00a0body surface area given for 30 minutes.\u00a0The usual\u00a0dose\u00a0for advanced pancreatic cancer is 125 mg \/ m\u00a0<sup>2<\/sup>\u00a0\u00a0 body surface area given for 30 minutes.\u00a0The usual\u00a0dose\u00a0for non-small cell lung cancer\u00a0is 100 mg \/ m\u00a02\u00a0body surface area given over 30 minutes.<\/p>\n\n\n\n<p><strong>How often will you receive Pazenir?<\/strong><\/p>\n\n\n\n<p>For the treatment of metastatic breast cancer, Pazenir is usually given once every three weeks (on day 1 of a 21-day cycle).<\/p>\n\n\n\n<p>For the treatment of advanced pancreatic cancer, Pazenir is given on days 1, 8, and 15 of each 28-day cycle and gemcitabine is given immediately after Pazenir.<\/p>\n\n\n\n<p>In the treatment of non-small cell lung cancer, Pazenir is given once a week (ie days 1, 8, and 15 in a 21-day cycle), and carboplatin is given once every three weeks (ie only day 1 in each 21-day cycle) immediately after Pazenir\u2011\u00a0dose\u00a0one has been given.<\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or nurse.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p><strong>Very common<\/strong>&nbsp;(may affect more than 1 user in 10):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Hair loss (most cases occurred within one month of starting paclitaxel treatment. When it does occur, hair loss is pronounced [over 50%] in most patients)<\/li><li>Rash<\/li><li>An abnormal decrease in the number of different types of\u00a0white blood cells\u00a0(\u00a0neutrophils,\u00a0lymphocytes,\u00a0or\u00a0leukocytes\u00a0) in the blood<\/li><li>Lack of\u00a0red blood cells<\/li><li>Reduction in the number of\u00a0platelets\u00a0in the blood<\/li><li>Effects on peripheral nerves (pain, numbness, tingling, or loss of sensation)<\/li><li>Pain in a joint or joints<\/li><li>Muscle pain<\/li><li>Nausea, diarrhea, constipation, soreness in the mouth, loss of appetite<\/li><li>Vomiting<\/li><li>Weakness and fatigue, fever<\/li><li>Dehydration, taste changes, weight loss<\/li><li>Low levels of\u00a0potassium\u00a0in the blood<\/li><li>Depression, sleep problems<\/li><li>Headache<\/li><li>Overindulge<\/li><li>Hard to breathe<\/li><li>Dizziness<\/li><li>Swollen mucous membranes and soft parts<\/li><li>Elevated liver function tests<\/li><li>Pain in arms and legs<\/li><li>Cough<\/li><li>Stomach pain<\/li><li>Nosebleed<\/li><\/ul>\n\n\n\n<p><strong>Common<\/strong>&nbsp;(may affect up to 1 in 10 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Itching, dry skin, nail problems<\/li><li>Infection, fever with decreased number of\u00a0white blood cell\u00a0types (\u00a0neutrophils\u00a0) in the blood,\u00a0redness, cold sores, severe\u00a0infection\u00a0in the blood that can be caused by the decreased number of\u00a0white blood cells<\/li><li>Reduced number of all\u00a0blood\u00a0cells<\/li><li>Chest or neck pain<\/li><li>Indigestion, feeling of discomfort in the abdomen<\/li><li>Nasal congestion<\/li><li>Back pain, skeletal pain<\/li><li>Decreased muscle coordination and difficulty reading, increased or decreased tear formation, eyelash waste<\/li><li>Changes in\u00a0heart rate\u00a0or heart rate,\u00a0heart failure<\/li><li>Lowered or increased\u00a0blood pressure<\/li><li>Redness\u00a0or swelling at the place where the needle was inserted into the body<\/li><li>Anxiety<\/li><li>Infection\u00a0of the lungs<\/li><li>Urinary\u00a0tract infection<\/li><li>Intestinal obstruction,\u00a0inflammation\u00a0of the colon,\u00a0inflammation\u00a0of the bile ducts<\/li><li>Acute\u00a0renal failure<\/li><li>Increased level of\u00a0bilirubin\u00a0in the blood<\/li><li>Coughing up of blood<\/li><li>Dry mouth, difficulty swallowing<\/li><li>Muscle weakness<\/li><li>Dimsyn<\/li><\/ul>\n\n\n\n<p><strong>Uncommon (<\/strong>&nbsp;may affect up to 1 in 100 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Increased weight, increased level of\u00a0lactate dehydrogenase\u00a0in the blood, decreased kidney function, increased blood sugar, increased level of phosphorus in the blood<\/li><li>Impaired reflexes or lack of reflexes, involuntary movements, pain along a nerve, fainting, dizziness when getting up, tremors, facial paralysis<\/li><li>Irritated eyes, aching eyes, red eyes, itchy eyes, double vision, impaired vision or seeing flashing light, blurred vision due to swelling of the retina (cystoid macular edema)<\/li><li>Ear pain, ringing in the ears<\/li><li>Cough with mucus, shortness of breath when walking or walking upstairs, runny nose or dry nose, decreased breathing noise, water in the lungs, loss of voice, blood clot in the lung, dryness in the throat<\/li><li>Gases, stomach cramps, painful or sore gums, rectal bleeding<\/li><li>Pain when urinating, frequent urination, blood in the urine, inability to hold urine<\/li><li>Fingernail pain, fingernail discomfort, loss of fingernails, hives, skin pain, red skin if exposed to sunlight, skin discoloration, increased sweating, night sweats, white areas on the skin, sores, swollen face<\/li><li>Decreased level of phosphorus in the blood, accumulation of fluid in the body, low albumin value in the blood, increased thirst, decreased level of\u00a0calcium\u00a0in the blood, decreased blood sugar, decreased level of\u00a0sodium\u00a0in the blood<\/li><li>Pain and swelling in the nose, skin infections,\u00a0infection\u00a0due to catheter tubing<\/li><li>Bruises<\/li><li>Tumor pain, tumor necrosis (tumor tissue dies)<\/li><li>Reduced\u00a0blood pressure\u00a0when standing up, cold hands and feet<\/li><li>Difficulty walking, swelling<\/li><li>Allergic reaction<\/li><li>Decreased liver function, increased size of the liver<\/li><li>Chest pain<\/li><li>Restlessness<\/li><li>Minor bleeding in the skin due to blood clotting<\/li><li>A condition that involves the breakdown of red\u00a0blood cells\u00a0and\u00a0acute\u00a0renal failure<\/li><\/ul>\n\n\n\n<p><strong>Rare<\/strong>&nbsp;(may affect up to 1 in 1,000 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Skin reaction to another agent or\u00a0pneumonia\u00a0after irradiation<\/li><li>Blood clotting<\/li><li>Very low\u00a0heart rate, heart attack<\/li><li>Leakage of drugs outside the vein<\/li><li>Irregular conduction of electrical impulses in the heart (atrioventricular block)<\/li><\/ul>\n\n\n\n<p><strong>Very rare (<\/strong>&nbsp;may affect up to 1 in 10,000 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Severe inflammation\/shedding of skin and mucous membranes (Stevens-Johnson syndrome,\u00a0toxic epidermal necrolysis\u00a0)<\/li><\/ul>\n\n\n\n<p><strong>No known frequency<\/strong>&nbsp;(can not be calculated from the available data):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Hardening\/thickening of the skin (\u00a0scleroderma\u00a0)<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Pazenir<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the carton and vial after EXP.\u00a0day.\u00a0or EXP.\u00a0The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>Unopened vials: Keep the vial in the outer carton until ready to use.&nbsp;Sensitive to light.<\/p>\n\n\n\n<p>After the first\u00a0preparation, the\u00a0dispersion\u00a0should\u00a0be used immediately.\u00a0If the\u00a0dispersion\u00a0is not used immediately, it can be stored in a refrigerator (2 \u00b0 C-8 \u00b0 C) for up to 24 hours in a vial, provided that the vial is in the outer carton to protect it from light.<\/p>\n\n\n\n<p>Prepared\u00a0dispersion\u00a0in\u00a0an infusion bag\u00a0can be stored for up to 24 hours at 2 \u00b0 C \u2013 8 \u00b0 C, protected from light, followed by 4 hours at 15 \u00b0 C \u2013 25 \u00b0 C.<\/p>\n\n\n\n<p>Physicians or pharmacists are responsible for disposing of unused Pazenir properly.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the pack and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<p>The active substance is paclitaxel.<\/p>\n\n\n\n<p>Each&nbsp;vial&nbsp;contains 100 mg of paclitaxel in the form of albumin-bound nanoparticles.<\/p>\n\n\n\n<p>After\u00a0reconstitution, each ml of\u00a0dispersion\u00a0contains 5 mg of paclitaxel in the form of albumin-bound nanoparticles.<\/p>\n\n\n\n<p>The other ingredients are human albumin (containing\u00a0sodium, sodium caprylate, and N-acetyl-DL-tryptophanate, see section 2 \u201cPazenir contains sodium\u201d).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>Pazenir is a white-yellow powder for\u00a0infusion\u00a0and dispersion.\u00a0Pazenir is supplied in glass vials containing 100 mg paclitaxel in the form of albumin-bound nanoparticles.<\/p>\n\n\n\n<p>Each pack contains 1 vial.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p><strong>Marketing Authorisation Holder<\/strong><\/p>\n\n\n\n<p>ratiopharm GmbH<\/p>\n\n\n\n<p>Graf-Arco-Stra\u00dfe 3<\/p>\n\n\n\n<p>89079 Ulm<\/p>\n\n\n\n<p>Germany<\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>Merckle GmbH<\/p>\n\n\n\n<p>Ludwig-Merckle-Stra\u00dfe 3<\/p>\n\n\n\n<p>89143 Blaubeuren<\/p>\n\n\n\n<p>Germany<\/p>\n\n\n\n<p>Pharmachemie BV<\/p>\n\n\n\n<p>Swensweg 5<\/p>\n\n\n\n<p>Haarlem<\/p>\n\n\n\n<p>2031 GA<\/p>\n\n\n\n<p>Netherlands<\/p>\n\n\n\n<p>Teva Pharma BV<\/p>\n\n\n\n<p>Swensweg 5<\/p>\n\n\n\n<p>2031 GA Haarlem<\/p>\n\n\n\n<p>Netherlands<\/p>\n\n\n\n<p>Teva Nederland BV<\/p>\n\n\n\n<p>Swensweg 5<\/p>\n\n\n\n<p>2031 GA Haarlem<\/p>\n\n\n\n<p>Netherlands<\/p>\n\n\n\n<p>Contact the representative of the marketing authorization holder to find out more about this medicine:<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td><strong>Belgium \/ Belgique \/ Belgien<\/strong>Teva Pharma Belgium NV \/ SA \/ AGTel \/ Tel: +32 3 820 73 73&nbsp;<\/td><td><strong>Lithuania<\/strong>UAB \u201cSicor Biotech\u201dTel: +370 5 266 02 03<\/td><\/tr><tr><td><strong>Bulgaria<\/strong>Actavis EADTel: +359 2 489 95 85<\/td><td><strong>Luxembourg \/ Luxemburg<\/strong>Teva Pharma Belgium NV \/ SA \/ AG,Tel: +32 3 820 73 73<\/td><\/tr><tr><td><strong>Czech Republic<\/strong>Teva Pharmaceuticals CR, sroTel: +420 251 007 111&nbsp;<\/td><td><strong>Hungary<\/strong>Teva Gy\u00f3gyszergy\u00e1r Zrt.Tel .: +36 1 288 6400<\/td><\/tr><tr><td><strong>Denmark<\/strong>Teva Denmark A \/ STel: +45 44 98 55 11&nbsp;<\/td><td><strong>Malta<\/strong>Teva Pharmaceuticals Ireland, L-Ireland:El: +353 (0) 1912 7700<\/td><\/tr><tr><td><strong>Germany<\/strong>ratiopharm GmbHTel: +49 731 402 02<\/td><td><strong>The Netherlands<\/strong>Teva Nederland BVTel: +31 (0) 800 0228400<\/td><\/tr><tr><td><strong>Eesti<\/strong>UAB Sicor Biotech Eesti subsidiaryTel: +372 661 0801<\/td><td><strong>Norway<\/strong>Teva Norway ASTel: +47 66 77 55 90<\/td><\/tr><tr><td><strong>Greece<\/strong>Specify \u0391\u0392\u0395\u0395:\u0397\u03bb: +30 211 880 5000<\/td><td><strong>Austria<\/strong>ratiopharm Arzneimittel Vertriebs-GmbHTel: +43 1 970070<\/td><\/tr><tr><td><strong>Spain<\/strong>Teva Pharma, SLUTel: +34 91 387 32 80<\/td><td><strong>Poland<\/strong>Teva Pharmaceuticals Polska Sp.&nbsp;z ooTel .: +48 22 345 93 00<\/td><\/tr><tr><td><strong>France<\/strong>Teva HealthTel: +33 1 55 91 78 00<\/td><td><strong>Portugal<\/strong>Teva Pharma &#8211; Pharmaceutical Products LdaTel: +351 214 767 550<\/td><\/tr><tr><td><strong>Croatia<\/strong>Pliva Hrvatska dooTel: + 385 1 37 20 000<\/td><td><strong>Romania<\/strong>Teva Pharmaceuticals SRLTel: +40 21 230 65 24<\/td><\/tr><tr><td><strong>Ireland<\/strong>Teva Pharmaceuticals IrelandTel: +353 (0) 1912 7700<\/td><td><strong>Slovenia<\/strong>Pliva Ljubljana dooTel: +386 1 58 90 390<\/td><\/tr><tr><td><strong>Iceland<\/strong>Actavis Pharmaceutical Iceland ehf.Phone: + 354 550 3300<\/td><td><strong>Slovak Republic<\/strong>Teva Pharmaceuticals Slovakia sroTel: +421 2 5726 7911<\/td><\/tr><tr><td><strong>Italy<\/strong>Teva Italia SrlTel: +39 0289 17981<\/td><td><strong>Finland \/ Finland<\/strong>ratiopharm OyPuh \/ Tel: +358 20 180 5900<\/td><\/tr><tr><td><strong>.\u03a0\u03c1\u03bf\u03c2<\/strong>Specify \u0391\u0392\u0395\u0395, Greece:\u0397\u03bb: +30 211 880 5000<\/td><td><strong>Sweden<\/strong>Teva Sweden ABTel: +46 42 12 11 00<\/td><\/tr><tr><td><strong>Latvia<\/strong>UAB Sicor Biotech subsidiary Latvij\u0101Tel: +371 67 323 666<\/td><td><strong>United Kingdom<\/strong>Teva UK LimitedTel: +44 1977 628 500<\/td><\/tr><\/tbody><\/table><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>The active substance in Pazenir is paclitaxel. Paclitaxel is bound to the human protein et albumin in the form of very small particles called nanoparticles. Paclitaxel belongs to a group of medicines called &#8220;taxanes&#8221; and is used to treat cancer.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,18527],"tags":[20574,21011,10249,20573,21007,21010,10250,21008,10251,21009],"class_list":["post-20556","post","type-post","status-publish","format-standard","hentry","category-medicines","category-p","tag-benefits-of-paclitaxel","tag-benefits-of-pazenir","tag-paclitaxel","tag-paclitaxel-side-effects","tag-pazenir","tag-pazenir-side-effects","tag-what-is-paclitaxel","tag-what-is-pazenir","tag-what-paclitaxel-is-used-for","tag-what-pazenir-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/20556","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=20556"}],"version-history":[{"count":3,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/20556\/revisions"}],"predecessor-version":[{"id":20597,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/20556\/revisions\/20597"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=20556"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=20556"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=20556"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}