{"id":20547,"date":"2022-04-06T11:15:19","date_gmt":"2022-04-06T11:15:19","guid":{"rendered":"https:\/\/zeepedia.com\/?p=20547"},"modified":"2022-04-07T10:06:12","modified_gmt":"2022-04-07T10:06:12","slug":"paroxiflex","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/paroxiflex\/","title":{"rendered":"Paroxiflex &#8211; Paroxetine uses, dose and side effects"},"content":{"rendered":"\n<p>20 mg&nbsp;film-coated tablets<br>paroxetine<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Paroxiflex is and what it is used for<\/h2>\n\n\n\n<p>Paroxiflex is used for treating depression and\/or anxiety disorders in adults.\u00a0The anxiety states that Paroxiflex is used for are: obsessive-compulsive disorder (repeated obsessive-compulsive disorder), panic disorder (attacks of panic disorder, including those that occur with\u00a0agoraphobia, ie fear of open spaces),\u00a0social phobia\u00a0(fear of or avoidance of social situations),\u00a0post-traumatic stress disorder.\u00a0stress syndrome\u00a0(anxiety after a traumatic experience) and\u00a0generalized anxiety disorder\u00a0(general severe anxiety or worry).<\/p>\n\n\n\n<p>Paroxiflex belongs to a group of medicines called selective serotonin reuptake inhibitors (\u00a0SSRIs\u00a0).\u00a0All people have a neurotransmitter in the brain called\u00a0serotonin.\u00a0People with depression or anxiety have lower levels of\u00a0serotonin\u00a0than others.\u00a0It is not completely known how Paroxiflex and other\u00a0SSRIs\u00a0work, but it could be because they increase the levels of\u00a0serotonin\u00a0in the brain.\u00a0Proper treatment of your depression or anxiety is important to help you improve.<\/p>\n\n\n\n<p>Paroxetine\u00a0contained in Paroxiflex may also be approved for the treatment of other conditions not mentioned in this product information.\u00a0Ask your doctor, pharmacist, or other healthcare professionals if you have any further questions, and always follow their instructions.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before using Paroxiflex<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not take Paroxiflex<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>If you are taking medicines called\u00a0monoamine oxidase inhibitors<\/strong>\u00a0(\u00a0MAOIs, including moclobemide, linezolid, and methylthioninium chloride (methylene blue) or have taken them at any time during the last two weeks, your doctor will advise you on how to start taking Paroxiflex after you have stopped\u00a0taking MAO inhibitors.<\/li><li>If you are taking a medicine for\u00a0psychosis\u00a0that contains either thioridazine\u00a0or pimozide.<\/li><li>If you are allergic\u00a0to\u00a0paroxetine, peanuts, soy, or any of the other ingredients of this medicine (listed in section 6).<\/li><li><strong>If any of the above applies to you,<\/strong>\u00a0tell your doctor before taking Paroxiflex.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist or nurse before taking Paroxiflex and ask yourself the following questions:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Are you taking any other medicines (see section\u00a0<em>Other medicines and Paroxiflex<\/em>\u00a0)?<\/li><li>Do you have kidney, liver, or heart problems?<\/li><li>Do you have\u00a0epilepsy\u00a0or have had seizures or seizures in the past?<\/li><li>Have you ever had manic episodes (overactive behavior or thoughts)?<\/li><li>Do you receive electroconvulsive therapy (ECT)?<\/li><li>Have you had a bleeding disorder or are you taking any other medicine that may increase the risk of bleeding (blood thinners such as\u00a0warfarin, antipsychotics such as phenazine or clozapine,\u00a0tricyclic antidepressants, painkillers, and anti-inflammatory\u00a0drugs, so-called\u00a0NSAIDs\u00a0) ) such as\u00a0<a href=\"https:\/\/zeepedia.com\/medical\/medicines\/tiplo-citrus\/\">acetylsalicylic acid<\/a>,\u00a0ibuprofen, celecoxib, etodolac,\u00a0diclofenac, meloxicam or if you are pregnant (see section\u00a0Pregnancy, breast-feeding and\u00a0fertility\u00a0)?<\/li><li>Do you have\u00a0diabetes?<\/li><li>Are you on a salt-reduced diet?<\/li><li>Do you have\u00a0glaucoma\u00a0(\u00a0glaucoma, increased pressure in the eye)?<\/li><li>Are you pregnant or planning to become pregnant (see section\u00a0Pregnancy, breastfeeding,<em> and\u00a0fertility<\/em>\u00a0)?<\/li><li>Are you under 18 (see\u00a0<em>Children and adolescents under 18<\/em>\u00a0in this leaflet)?<\/li><\/ul>\n\n\n\n<p><strong>If you answer YES to any of these questions<\/strong>\u00a0and have not previously discussed this with your doctor,\u00a0<strong>consult your doctor again and ask how to apply Paroxiflex<\/strong>.<\/p>\n\n\n\n<p><strong>If you start to feel worse and have thoughts of harming yourself<\/strong><\/p>\n\n\n\n<p>You who are depressed and\/or suffer from worry\/anxiety can sometimes have thoughts of harming yourself or committing suicide.\u00a0These symptoms may worsen when you start taking antidepressants, as it takes time for a drug of this type to take effect, usually about 2 weeks, sometimes longer.<\/p>\n\n\n\n<p>These thoughts may be common:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you have previously had thoughts of harming yourself or committing suicide,<\/li><li>if you are younger than 25 years.&nbsp;Studies have shown that young adults (younger than 25 years) with mental illness who are treated with antidepressant drugs have an increased risk of suicidal thoughts and thoughts of harming themselves.<\/li><\/ul>\n\n\n\n<p><strong>Contact a doctor as soon as possible or go to the nearest hospital<\/strong>&nbsp;if you have thoughts of injuring yourself or committing suicide.<\/p>\n\n\n\n<p><strong>It can be helpful to tell a relative or close friend<\/strong>\u00a0that you are depressed and\/or suffering from anxiety.\u00a0Feel free to ask them to read this leaflet.\u00a0You can also ask them to tell you if they think you are feeling worse or if they think your behavior is changing.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children and young people under 18 years of age<\/h2>\n\n\n\n<p><strong>Paroxiflex should not be used by children and adolescents under 18 years of age<\/strong>.\u00a0The risk of\u00a0side effects\u00a0such as suicide attempts, suicidal thoughts, and hostility (mainly aggression, defiance, and anger) is greater in patients under 18 years of age using Paroxiflex.\u00a0If your doctor has prescribed Paroxiflex for you (or your child) and you want to discuss this, you should see your doctor again.\u00a0You should tell your doctor if any of the above symptoms occur or if such symptoms worsen while you (or your child) are taking Paroxiflex.\u00a0The long-term effects on growth, maturity, and\u00a0cognitive\u00a0and behavioral development have not been established for children and adolescents under 18 years of age.<\/p>\n\n\n\n<p>In studies with\u00a0paroxetine\u00a0in patients under 18 years of age, the following common\u00a0side effects\u00a0occurred in less than 1 in 10 children\/adolescents: Increased suicidal ideation and suicide attempts, self-harming behavior, hostile, aggressive, or unfriendly behavior, loss of appetite, tremors, abnormal sweating, hyperactivity ( excess energy), agitation, emotional changes (including crying and mood swings).\u00a0The studies showed that the same symptoms also occurred in children and adolescents who received\u00a0a placebo\u00a0(an inactive substance) instead of\u00a0paroxetine, but less often.<\/p>\n\n\n\n<p>Some patients in these studies with people under the age of 18 experienced withdrawal symptoms when they stopped taking\u00a0paroxetine.\u00a0These symptoms are mostly similar to those seen in adults after discontinuation of\u00a0paroxetine\u00a0treatment (see section 3.\u00a0How to take Paroxiflex\u00a0in this leaflet).\u00a0In addition, patients under 18 years of age usually experienced (less than 1 in 10) abdominal pain, nervousness, and emotional changes (including crying, mood swings, attempted self-harm, thoughts of suicide, and suicide attempts).<\/p>\n\n\n\n<p>Drugs such as Paroxiflex (so-called&nbsp;SSRIs&nbsp;) can cause symptoms of sexual&nbsp;dysfunction&nbsp;(see section 4).&nbsp;In some cases, these symptoms have persisted after discontinuation of treatment.<\/p>\n\n\n\n<p><strong>Important&nbsp;side effects&nbsp;have been seen with Paroxiflex<\/strong><\/p>\n\n\n\n<p>Some patients taking Paroxiflex develop something called\u00a0akathisia, which means that they\u00a0feel restless and can not sit or standstill.\u00a0Others may develop something called\u00a0serotonergic syndrome\u00a0when they have some or all of the following symptoms: confusion, restlessness, sweating, tremors, chills, hallucinations (seeing or hearing strange things), sudden muscle twitching, or rapid heartbeat.\u00a0If you experience any of these symptoms, consult a doctor.\u00a0For more information on these and other\u00a0side effects\u00a0of Paroxiflex, see section 4.\u00a0<em>Any\u00a0side effects\u00a0are listed<\/em>\u00a0in this leaflet.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Paroxiflex<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.<\/p>\n\n\n\n<p>Some medicines may affect the way Paroxiflex works or increase the risk of\u00a0side effects.\u00a0Paroxiflex may also affect the way other medicines work.\u00a0This applies to the following medicines and substances contained in medicines:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Medicines called\u00a0<strong>MAO inhibitors<\/strong>, including moclobemide and methylthioninium chloride (methylene blue) &#8211; see section\u00a0Do not take Paroxiflex\u00a0in this leaflet<\/li><li>Thioridazine or pimozide, which are available in medicines for\u00a0psychosis\u00a0&#8211; see section\u00a0Do not take Paroxiflex\u00a0in\u00a0this leaflet.<\/li><li>Linezolid, which is found in\u00a0antibiotics\u00a0&#8211; see section\u00a0Do not take Paroxiflex\u00a0in this leaflet.<\/li><li>Acetylsalicylic acid,\u00a0ibuprofen,\u00a0or other so-called\u00a0NSAIDs\u00a0(non-steroidal anti-inflammatory drugs) such as celecoxib, etodolac,\u00a0diclofenac,\u00a0and meloxicam are used in\u00a0pain and\u00a0inflammation.<\/li><li><a href=\"https:\/\/zeepedia.com\/medical\/medicines\/tramadol-retard-krka\/\">Tramadol<\/a> and pethidine are used for pain.<\/li><li>Fentanyl, used in anesthesia or for the treatment of\u00a0chronic\u00a0pain<\/li><li>Drugs called triptans, such as sumatriptan, are used to\u00a0treat migraines.<\/li><li>Other antidepressants include other\u00a0SSRIs\u00a0and\u00a0tricyclic antidepressants\u00a0such as clomipramine, nortriptyline, and desipramine.<\/li><li>A dietary supplement called tryptophan.<\/li><li>Drugs such as lithium,\u00a0risperidone, perphenazine, and clozapine (so-called antipsychotics) are used to treat certain\u00a0psychiatric illnesses.<\/li><li>A combination of fosamprenavir and ritonavir is used to\u00a0treat\u00a0HIV\u00a0infection.<\/li><li>St. John&#8217;s wort is a natural remedy for\u00a0depression.<\/li><li>Phenobarbital,\u00a0phenytoin, sodium valproate, or carbamazepine for the treatment of\u00a0seizures or\u00a0epilepsy.<\/li><li>Atomoxetine is a drug used to treat\u00a0ADHD\u00a0(Attention Deficit Hyperactivity Disorder).<\/li><li>Procyclidine is used to relieve tremors, especially in\u00a0Parkinson&#8217;s disease.<\/li><li>Warfarin\u00a0or other\u00a0blood thinners\u00a0(so-called\u00a0anticoagulants\u00a0).<\/li><li>Propafenone,\u00a0flecainide,\u00a0and medicines are used to treat\u00a0an irregular heartbeat.<\/li><li>Metoprolol is a\u00a0beta-blocker used to treat\u00a0high\u00a0blood pressure\u00a0and heart problems.<\/li><li>Pravastatin is used to treat\u00a0high\u00a0cholesterol<\/li><li>Rifampicin is used to treat\u00a0tuberculosis\u00a0and leprosy.<\/li><li>Tamoxifen (used to treat breast cancer).<\/li><\/ul>\n\n\n\n<p><strong>If you are taking or have recently taken any of the medicines listed above<\/strong>&nbsp;and have not already discussed these with your doctor, see your doctor again and ask for advice.&nbsp;Your&nbsp;dose&nbsp;may need to be changed or you may need another medicine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Paroxiflex with food, drink, and alcohol<\/h2>\n\n\n\n<p>Do not use alcohol while taking Paroxiflex.\u00a0Alcohol can worsen your symptoms or\u00a0side effects.\u00a0Taking Paroxiflex in the morning with food reduces the risk of nausea.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, breastfeeding, and fertility<\/h2>\n\n\n\n<p><strong>If you are taking Paroxiflex and have recently learned that you are pregnant<\/strong>, talk to your doctor immediately.\u00a0If you are planning to become pregnant, you should also talk to your doctor about this as some studies have shown an increased risk of heart defects in children of mothers who used\u00a0paroxetine\u00a0during the first months of pregnancy.\u00a0In these studies, it was found that 2 children out of 100 (2%) or less, whose mothers used\u00a0paroxetine\u00a0early in pregnancy, were born with heart defects, compared with 1 child out of 100 (1%) in the general population.\u00a0Regarding the total incidence of various malformations, there is no difference between children and mothers who used\u00a0paroxetine during pregnancy compared to newborns in the general population.\u00a0You and your doctor can decide together whether it is better to switch to another treatment or whether to gradually phase out Paroxiflex treatment while you are pregnant.\u00a0However, depending on the circumstances, your doctor may decide that continued treatment with Paroxiflex is better for you.<\/p>\n\n\n\n<p>Tell your midwife or doctor that you are using Paroxiflex When medicines such as Paroxiflex are used during pregnancy, especially during the last three months, they may increase the risk of a serious condition called&nbsp;persistent&nbsp;pulmonary&nbsp;hypertension&nbsp;in the newborn (PPHN).&nbsp;This condition causes the baby to breathe faster and look blue.&nbsp;The symptoms usually appear within 24 hours of the baby being born.&nbsp;If this affects your baby, contact a midwife or doctor immediately.<\/p>\n\n\n\n<p><strong>If you are taking Paroxiflex during the last 3 months of pregnancy<\/strong>, tell your midwife, as your baby may experience some postpartum symptoms.\u00a0Such symptoms usually begin during the first 24 hours after birth and include the baby having difficulty sleeping or eating properly, difficulty breathing, bluish skin, the baby being too hot or too cold, vomiting, crying persistently, having tense or limp muscles, has decreased alertness, tremors, twitching or cramps.\u00a0If your baby gets any of these symptoms after birth,\u00a0consult a doctor or midwife for advice.<\/p>\n\n\n\n<p>If you take Paroxiflex at the end of your pregnancy, there may be an increased risk of heavy vaginal bleeding shortly after delivery, especially if you have a history of bleeding disorders.&nbsp;Your doctor or midwife should be informed that you are taking Paroxiflex so that they can advise you on this.<\/p>\n\n\n\n<p><strong>Paroxiflex can be excreted in milk in very small amounts<\/strong>.\u00a0If you are taking Paroxiflex, talk to your doctor before breastfeeding.<\/p>\n\n\n\n<p>In animal studies, it has been shown that\u00a0paroxetine\u00a0reduces the quality of semen.\u00a0In theory, this could affect\u00a0fertility, but no such reducing effect of\u00a0paroxetine\u00a0on\u00a0fertility\u00a0has yet been demonstrated in humans.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Possible\u00a0side effects\u00a0of Paroxiflex include dizziness, confusion, drowsiness, or blurred vision.\u00a0If you get these\u00a0side effects, do not drive or use machines.<\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects.\u00a0Descriptions of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Paroxiflex contains soy lecithin and sodium<\/h2>\n\n\n\n<p>If you are allergic to peanuts or soy, do not use this medicine.&nbsp;<\/p>\n\n\n\n<p>This medicine contains less than 1 mmol (23 mg)&nbsp;sodium&nbsp;per tablet, ie essentially &#8216;sodium-free&#8217;.&nbsp;next to &#8220;sodium-free&#8221;.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to use Paroxiflex<\/h2>\n\n\n\n<p><strong>Always take Paroxiflex exactly as your doctor has told you.&nbsp;<\/strong>If you are not sure, ask your doctor or pharmacist.<\/p>\n\n\n\n<p>Sometimes you may need to take more than one tablet or just half a tablet.\u00a0This table shows you the number of tablets to take.<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><th scope=\"col\"><strong>Dose<\/strong><\/th><th scope=\"col\"><strong>Number of tablets to be taken<\/strong><\/th><\/tr><tr><td>10 mg<\/td><td>Half a tablet<\/td><\/tr><tr><td>20 mg<\/td><td>A pill<\/td><\/tr><tr><td>30 mg<\/td><td>One and a half tablets<\/td><\/tr><tr><td>40 mg<\/td><td>Two tablets<\/td><\/tr><tr><td>50 mg<\/td><td>Two and a half tablets<\/td><\/tr><tr><td>60 mg<\/td><td>Three tablets<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p>The usual\u00a0dosage\u00a0for different conditions is given in the table below<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><thead><tr><td>&nbsp;<\/td><td>Starting dose<\/td><td>Recommended daily&nbsp;dose<\/td><td>Maximum daily&nbsp;dose<\/td><\/tr><\/thead><tbody><tr><th scope=\"row\">Depression<\/th><td>20 mg<\/td><td>20 mg<\/td><td>50 mg<\/td><\/tr><tr><th scope=\"row\">Obsessive-compulsive disorder<\/th><td>20 mg<\/td><td>40 mg<\/td><td>60 mg<\/td><\/tr><tr><th scope=\"row\">Panic syndrome<\/th><td>10 mg<\/td><td>40 mg<\/td><td>60 mg<\/td><\/tr><tr><th scope=\"row\">Social Phobia<\/th><td>20 mg<\/td><td>20 mg<\/td><td>50 mg<\/td><\/tr><tr><th scope=\"row\">Posttraumatic stressyndrome<\/th><td>20 mg<\/td><td>20 mg<\/td><td>50 mg<\/td><\/tr><tr><th scope=\"row\">Generalized anxiety disorder<\/th><td>20 mg<\/td><td>20 mg<\/td><td>50 mg<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p><strong>Your doctor will advise you on which\u00a0dose\u00a0of Paroxiflex to start with<\/strong>.\u00a0Most people start to feel better after a couple of weeks.\u00a0If you do not feel better after this time, consult your doctor for advice.\u00a0Your doctor may decide to increase your\u00a0dose\u00a0gradually, by 10 mg at a time, up to the highest daily\u00a0dose.<\/p>\n\n\n\n<p><strong>Take your tablets in the morning with food.<\/strong><\/p>\n\n\n\n<p><strong>Swallow the tablets with a glass of water.<\/strong><\/p>\n\n\n\n<p><strong>Do not chew them.<\/strong><\/p>\n\n\n\n<p>The tablet can be divided into equal\u00a0doses.<\/p>\n\n\n\n<p>Doctors will discuss with you how long you need to continue taking Paroxiflex.&nbsp;It can be for several months or even longer.<\/p>\n\n\n\n<p><strong>Elderly patients<\/strong><\/p>\n\n\n\n<p>The maximum&nbsp;dose&nbsp;for patients over 65 years of age is 40 mg per day.<\/p>\n\n\n\n<p><strong>Patients with liver or kidney disease<\/strong><\/p>\n\n\n\n<p>If you have liver problems or severe kidney disease, your doctor may decide that you should take a lower&nbsp;dose&nbsp;of Paroxiflex than recommended.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you take more Paroxiflex than you should<\/h2>\n\n\n\n<p><strong>Never take more tablets than your doctor recommends<\/strong>.\u00a0If you have ingested too much medicine or if e.g.\u00a0a child ingested the medicine by mistake, contact a doctor or hospital for risk assessment and advice.\u00a0Show the medicine package.\u00a0A person taking an overdose of Paroxiflex may experience the symptoms listed in section 4.\u00a0Possible\u00a0side effects,\u00a0or the following symptoms: vomiting, dilated\u00a0pupils, fever, headache, uncontrollable muscle contraction.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to take Paroxiflex<\/h2>\n\n\n\n<p>Take Paroxiflex at the same time each day.<\/p>\n\n\n\n<p><strong>If you forget to take a\u00a0dose\u00a0and think about it before going to bed at night<\/strong>, take a\u00a0dose\u00a0immediately.\u00a0Continue as usual the next day.<\/p>\n\n\n\n<p><strong>If you forget to take a\u00a0dose\u00a0and only remember to take it overnight or the next day<\/strong>, do not take any extra\u00a0dose.\u00a0Take the next\u00a0dose\u00a0at the usual time.\u00a0You may experience some withdrawal symptoms, but these will disappear after the next\u00a0dose.<\/p>\n\n\n\n<p>Do not take a double\u00a0dose\u00a0to make up for a forgotten\u00a0dose.<\/p>\n\n\n\n<p><strong>If you do not feel any improvement<\/strong><\/p>\n\n\n\n<p><strong>Paroxiflex will not relieve your symptoms immediately<\/strong>&nbsp;&#8211; all antidepressants require time to work.&nbsp;Some patients start to feel better after a couple of weeks while for others it may take a little longer.&nbsp;Some people who take antidepressants experience a worsening before they start to feel better.&nbsp;If you do not start to feel better after a couple of weeks, contact your doctor for advice.&nbsp;Your doctor should suggest a return visit a few weeks after you start treatment.&nbsp;Tell your doctor if you do not notice any improvement.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop taking Paroxiflex<\/h2>\n\n\n\n<p><strong>Do not stop taking Paroxiflex until your doctor tells you to.<\/strong><\/p>\n\n\n\n<p><strong>When stopping Paroxiflex, your<\/strong>\u00a0doctor will help you slowly reduce your\u00a0dose\u00a0over several weeks or months to reduce the risk of withdrawal symptoms.\u00a0One way to do this is to gradually reduce your Paroxiflex\u00a0dose\u00a0by 10 mg per week.\u00a0Most people experience that the withdrawal symptoms are mild and go away on their own within 2 weeks.\u00a0For some patients, the symptoms may be more severe or more prolonged.<\/p>\n\n\n\n<p><strong>If you experience withdrawal symptoms<\/strong>&nbsp;when you end your treatment, your doctor may decide that you&nbsp;should&nbsp;stop at a slower pace.&nbsp;Contact your doctor if you experience severe withdrawal symptoms.&nbsp;Your doctor may ask you to start taking Paroxiflex again and then end the treatment more slowly.<\/p>\n\n\n\n<p><strong>Even if you experience withdrawal symptoms, it will be possible for you to stop taking Paroxiflex.<\/strong><\/p>\n\n\n\n<p><strong>Withdrawal symptoms that may occur when treatment is stopped<\/strong><\/p>\n\n\n\n<p>Studies show that 3 out of 10 patients experience one or more withdrawal symptoms when treatment with&nbsp;paroxetine&nbsp;is stopped.&nbsp;Some withdrawal symptoms occur more often than others.<\/p>\n\n\n\n<p><strong>Common withdrawal symptoms may affect up to 1 in 10 people<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Dizziness (feeling of instability, balance difficulties)<\/li><li>Sensory disturbances such as ant crawling burning sensation, and, less commonly, a sensation of electric shock (including in the head), as well as buzzing, hissing, whistling, ringing, or other persistent sounds in the ears (\u00a0tinnitus\u00a0)<\/li><li>Sleep disorders (vivid dreams, nightmares, difficulty sleeping).<\/li><li>Anxiety<\/li><li>Headache<\/li><\/ul>\n\n\n\n<p><strong>Uncommon withdrawal symptoms may affect up to 1 in 100 people<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Nausea<\/li><li>Sweating (including night sweats)<\/li><li>Restlessness or agitation<\/li><li>Tremor&nbsp;(shaking)<\/li><li>Confusion or disorientation<\/li><li>Diarrhea<\/li><li>Emotional instability or irritability<\/li><li>Visual disturbances<\/li><li>Fluttering or throbbing heartbeat (palpitations)<\/li><\/ul>\n\n\n\n<p><strong>Contact a doctor if you are worried about withdrawal symptoms when treatment with Paroxiflex is stopped.<\/strong><\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.\u00a0Side effects\u00a0occur more often during the first weeks of treatment with Paroxiflex.<\/p>\n\n\n\n<p><strong>If you get any of the following&nbsp;side effects&nbsp;during treatment, contact your doctor immediately or consult a hospital<\/strong><\/p>\n\n\n\n<p><strong>Uncommon&nbsp;side effects&nbsp;may affect up to 1 in 100 people:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>If you get unusual bruising or bleeding<\/strong>, bloody vomiting, or blood in the stool, consult a doctor or see a hospital immediately.<\/li><li><strong>If you have difficulty urinating, consult a doctor or go to a hospital immediately.<\/strong><\/li><\/ul>\n\n\n\n<p><strong>Rare\u00a0side effects\u00a0may affect up to 1 in 1,000 people:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>If you have a seizure, contact your doctor or hospital immediately.<\/strong><\/li><li><strong>If you feel restless and have difficulty sitting or standing still<\/strong>, it may be something called\u00a0akathisia.\u00a0Increasing the Paroxiflex\u00a0dose\u00a0may worsen these symptoms.\u00a0Contact a doctor if you experience these symptoms.<\/li><li>If you feel tired, weak, or confused and have sore, stiff, or uncoordinated muscles, this may be due to too low a level of sodium in the blood.\u00a0<strong>Contact a doctor<\/strong>\u00a0if you get these symptoms.<\/li><\/ul>\n\n\n\n<p><strong>Very rare\u00a0side effects\u00a0may affect up to 1 in 10,000 people:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Allergic reactions (which may be severe) to Paroxifle<\/strong>\u00a0x. If you develop red and lumpy skin rash, swelling of eyelids, face, lips, mouth or tongue,\u00a0itching\u00a0or difficulty breathing (shortness of breath), or swallowing and feeling weak or dizzy resulting in fainting or unconsciousness,\u00a0consult a doctor or see a hospital immediately.<\/li><li>If you have one or more of these symptoms, it may be a so-called serotonergic syndrome.\u00a0Symptoms include confusion, restlessness, sweating, tremors, chills, hallucinations (hearing or seeing strange things), sudden muscle twitching, or palpitations.\u00a0Contact a doctor\u00a0if you experience this.<\/li><li>Acute\u00a0glaucoma.\u00a0If you get pain in your eyes and you have blurred vision,\u00a0consult a doctor.<\/li><li>Severe rash (erythema multiforme,\u00a0Stevens-Johnson\u00a0syndrome, and\u00a0toxic epidermal necrolysis\u00a0), which is potentially life-threatening and requires immediate medical attention.<\/li><li>These first appear as round spots often with central blisters usually on the arms and hands or legs and feet, more severe skin rashes may include blisters on the chest and back.\u00a0Severe forms of skin rash can develop into widespread skin rash that can be life-threatening.<\/li><li>If you get a rash or these skin symptoms, stop taking Paroxiflex and contact your doctor immediately.<\/li><\/ul>\n\n\n\n<p><strong>Has been reported (occurs in the unknown number of users):<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Thoughts of harming yourself or committing suicide (see section 2. Warnings and precautions).<\/li><li>Aggression.<\/li><\/ul>\n\n\n\n<p><strong>Other possible\u00a0side effects\u00a0are during the treatment<\/strong><\/p>\n\n\n\n<p><strong>Very common&nbsp;side effects&nbsp;may affect more than 1 in 10 people.<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Nausea.\u00a0Taking Paroxiflex in the morning with food reduces the risk of nausea.<\/li><li>Change in sexual drive or function e.g.\u00a0missed orgasm and, in men,\u00a0erectile dysfunction\u00a0and ejaculation.<\/li><li>Concentration problems<\/li><\/ul>\n\n\n\n<p><strong>Common&nbsp;side effects&nbsp;may affect up to 1 in 10 people<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Loss of appetite<\/li><li>Difficulty sleeping or drowsiness<\/li><li>Abnormal dreams (including nightmares)<\/li><li>Dizziness or tremors (&nbsp;tremor&nbsp;)<\/li><li>Headache<\/li><li>Indignation<\/li><li>Unusual weakness<\/li><li>Dimsyn<\/li><li>Yawning,&nbsp;dry mouth<\/li><li>Diarrhea or constipation<\/li><li>Vomiting<\/li><li>Weight gain<\/li><li>Sweating<\/li><li>Increased cholesterol levels<\/li><\/ul>\n\n\n\n<p><strong>Uncommon, may affect up to 1 in 100 people<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Short-term increase or decrease in\u00a0blood pressure, faster\u00a0pulse\u00a0than normal<\/li><li>Movement retardation, stiffness, shaking, or abnormal movements in the mouth or tongue<\/li><li>Rash<\/li><li>Itching<\/li><li>Confusion<\/li><li>A short-term drop in\u00a0blood pressure\u00a0when you get up can make you feel dizzy or faint<\/li><li>Hallucinations (seeing or hearing strange things)<\/li><li>Dilated pupils (\u00a0mydriasis\u00a0)<\/li><li>Difficulty urinating (\u00a0urinary retention\u00a0) or uncontrollable, involuntary urination (urinary incontinence)<\/li><li>If you are a diabetic patient, you may experience a loss of control of your blood sugar levels while taking Paroxiflex.\u00a0Talk to your doctor about adjusting the\u00a0dose\u00a0of your\u00a0insulin\u00a0or your diabetes medicine.<\/li><\/ul>\n\n\n\n<p><strong>Rare\u00a0side effects\u00a0may affect up to 1 in 1,000 people<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Abnormal production of breast milk in men and women<\/li><li>Slow\u00a0pulse<\/li><li>Liver effects seen in blood tests when testing your liver function<\/li><li>Panic attacks<\/li><li>Overactive behavior or thoughts (mania)<\/li><li>The feeling of being outside your own body (depersonalization)<\/li><li>Anxiety<\/li><li>Pain in joints or muscles<\/li><li>Increase of\u00a0hormone\u00a0and\u00a0prolactin\u00a0in the blood<\/li><li>Need to move the legs (or other parts of the body) to stop restless legs.<\/li><\/ul>\n\n\n\n<p><strong>Very rare\u00a0side effects\u00a0may affect up to 1 in 10,000 people<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Yellowing of the skin or whites of the eyes due to liver problems,<\/li><li>Retention of fluid or water in the body, which can cause swelling in the arms or legs<\/li><li>Sensitivity to sunlight<\/li><li>Painful and persistent&nbsp;erection&nbsp;of the penis<\/li><li>Decreased number of&nbsp;platelets&nbsp;in the blood<\/li><\/ul>\n\n\n\n<p><strong>Has been reported (occurs in an unknown number of users):<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Tooth grinding<\/li><li>Inflammation\u00a0of the colon (which causes diarrhea).<\/li><li>Severe vaginal bleeding shortly after delivery (\u00a0postpartum hemorrhage), see Pregnancy, breastfeeding, and\u00a0fertility\u00a0in section 2 for more information.<\/li><\/ul>\n\n\n\n<p><em>Other possible side effects:<\/em><\/p>\n\n\n\n<p>An increased risk of bone fractures has been seen in patients taking this type of drug.<\/p>\n\n\n\n<p>Some patients have experienced buzzing, hissing, whistling, ringing, or other persistent sounds in their ears (\u00a0tinnitus\u00a0) when using\u00a0paroxetine.<\/p>\n\n\n\n<p>If you have any worries about using Paroxiflex, talk to your doctor or pharmacist for advice.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Paroxiflex<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the blister or jar and the carton.\u00a0The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>No special storage instructions.<\/p>\n\n\n\n<p>If you use half tablets, be sure to store them safely in the package.<\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the pack and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<p>The active substance is&nbsp;paroxetine&nbsp;(20 mg).<\/p>\n\n\n\n<p>Other ingredients are:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Tablet core: magnesium stearate, sodium starch glycollate (type A), mannitol, microcrystalline cellulose<\/li><li>Tablet coating: basic butylated methacrylate copolymer, polyvinyl alcohol, talc, soy lecithin, xanthan gum, and titanium dioxide (E171)<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>Paroxiflex 20 mg film-coated tablet is white\/off-white, biconvex, round, film-coated, scored, and marked with \u201cP\u201d on one side and \u201c20\u201d on the other.\u00a0The tablet has a score line on both sides.\u00a0The tablet can be divided into two equal\u00a0doses.<\/p>\n\n\n\n<p>Paroxiflex 20 mg is available in<\/p>\n\n\n\n<p>Blister packs (Al \/ Al) containing 20, 50, 60 and 100 tablets, 5 x 20 and 10 x 20 tablets or<\/p>\n\n\n\n<p>jars containing (Polypropylene with LDPE lid) with desiccants 100, 200, and 250 tablets.<\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p><strong>Marketing Authorization Holder and Manufacturer<\/strong><\/p>\n\n\n\n<p>STADA Arzneimittel AG<\/p>\n\n\n\n<p>Stadastrasse 2-18<\/p>\n\n\n\n<p>61118 Bad Vilbel<\/p>\n\n\n\n<p>Germany<\/p>\n\n\n\n<p><strong>Other manufacturers:<\/strong><\/p>\n\n\n\n<p>Balkanpharma &#8211; Dupnitsa AD<\/p>\n\n\n\n<p>3 Samokovsko Shosse Str.<\/p>\n\n\n\n<p>Dupnitsa 2600<\/p>\n\n\n\n<p>Bulgaria<\/p>\n\n\n\n<p><strong>Local representative<\/strong><\/p>\n\n\n\n<p>STADA Nordic ApS<\/p>\n\n\n\n<p>Marielundvej 46 A<\/p>\n\n\n\n<p>2730 Herlev<\/p>\n\n\n\n<p>Denmark<\/p>\n\n\n\n<p>It can also be helpful for you to contact a self-help or patient organization support group to find out more about your illness.\u00a0Your doctor can give you the detailed information.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Paroxiflex is used for treating depression and \/ or anxiety disorders in adults. The anxiety states that Paroxiflex is used for are: obsessive-compulsive disorder (repeated obsessive-compulsive disorder), panic disorder (attacks of panic disorder, including those that occur with agoraphobia , ie fear of open spaces), social phobia (fear of or avoidance of social situations), post-traumatic stress disorder . stress syndrome (anxiety after a traumatic experience) and generalized anxiety disorder (general severe anxiety or worry).<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,18527],"tags":[21045,21051,21040,21044,21043,21046,21050,21041,21047,21042,21048],"class_list":["post-20547","post","type-post","status-publish","format-standard","hentry","category-medicines","category-p","tag-benefits-of-paroxetine","tag-benefits-of-paroxiflex","tag-paroxetine","tag-paroxetine-side-effects","tag-paroxetine-tablet","tag-paroxiflex","tag-paroxiflex-side-effects","tag-what-is-paroxetine","tag-what-is-paroxiflex","tag-what-paroxetine-is-used-for","tag-what-paroxiflex-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/20547","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=20547"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/20547\/revisions"}],"predecessor-version":[{"id":20601,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/20547\/revisions\/20601"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=20547"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=20547"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=20547"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}