Pregnancy<\/strong><\/p>\n\n\n\nIf you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<\/p>\n\n\n\n
As the risk of congenital malformations (cardiovascular malformations) is slightly increased if you take\u00a0Paroxetine\u00a0Orion during the first three months of pregnancy, you must inform your doctor if you are planning to become pregnant or are already pregnant.\u00a0Your doctor must decide if treatment with\u00a0Paroxetine\u00a0Orion is necessary or if an alternative treatment can be used.<\/p>\n\n\n\n
Tell your midwife or doctor that you are using Paroxetine Orion. When drugs such as Paroxetine Orion are used during pregnancy, especially during the last three months, they may increase the risk of a serious condition called persistent pulmonary hypertension in the newborn (PPHN). This condition causes the baby to breathe faster and look blue. The symptoms usually appear within 24 hours of the baby being born. If this affects your baby, contact a midwife or doctor immediately.<\/p>\n\n\n\n
You should not abruptly discontinue treatment with Paroxetine Orion.<\/p>\n\n\n\n
Tell your doctor if you are using\u00a0Paroxetine\u00a0Orion during the last three months of pregnancy as your baby may have symptoms of treatment at birth.\u00a0These symptoms usually appear during the first 24 hours after delivery.\u00a0Symptoms may include the inability to sleep or eat enough, difficulty breathing, bluish skin or elevated or lowered body temperature, vomiting, persistent crying, stiff or limp muscles, lethargy, tremors, nervousness, or seizures.\u00a0If your baby has any of these symptoms at birth, talk to your doctor.<\/p>\n\n\n\n
If you take Paroxetine Orion at the end of your pregnancy, there may be an increased risk of heavy vaginal bleeding shortly after delivery, especially if you have a history of bleeding disorders. Your doctor or midwife should be informed that you are taking Paroxetine Orion so that they can advise you on this.<\/p>\n\n\n\n
Breast-feeding<\/strong><\/p>\n\n\n\nSmall amounts of\u00a0Paroxetine\u00a0Orion may pass into breast milk.\u00a0Talk to your doctor before breastfeeding your baby if you are taking\u00a0Paroxetine\u00a0Orion.<\/p>\n\n\n\n
Fertility<\/strong><\/p>\n\n\n\nIn animal studies, it has been shown that\u00a0paroxetine\u00a0reduces the quality of semen.\u00a0In theory, this could affect\u00a0fertility, but no such reducing effect of\u00a0paroxetine\u00a0on\u00a0fertility\u00a0has yet been demonstrated in humans.<\/p>\n\n\n\n
Driving and using machines<\/h2>\n\n\n\n
Paroxetine\u00a0Orion can cause\u00a0side effects\u00a0(such as dizziness, drowsiness, and confusion) that affect your ability to concentrate and react.\u00a0If you get these\u00a0side effects, do not drive, use machines or perform any other activity where you need to be alert and focused.<\/p>\n\n\n\n
You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects.\u00a0Descriptions of these\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n
Important information about some of the ingredients of Paroxetine Orion<\/h2>\n\n\n\n
This medicine contains 9.5 mg of lactose (monohydrate). If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.<\/p>\n\n\n\n
Other ingredients<\/strong><\/p>\n\n\n\nThis medicine contains less than 1 mmol (23 mg) sodium per tablet, ie essentially ‘sodium-free’.<\/p>\n\n\n\n
How to take Paroxetine Orion<\/h2>\n\n\n\n
Always take Paroxetine Orion exactly as your doctor or pharmacist has told you. Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n
The recommended dose is:<\/strong><\/p>\n\n\n\nAdults<\/strong><\/p>\n\n\n\nDepression<\/em><\/p>\n\n\n\nThe recommended dose is 20 mg daily. Depending on the treatment response, the dose may be increased gradually up to 50 mg daily in increments of 10 mg.<\/p>\n\n\n\n
Usually, the patient begins to improve after one week, but it may take two weeks until the improvements are noticed.\u00a0The treatment should last for at least 6 months.<\/p>\n\n\n\n
Obsessive-compulsive disorder and obsessive-compulsive disorder (obsessive-compulsive disorder)<\/em><\/p>\n\n\n\nThe starting dose is 20 mg daily. Depending on the treatment response, the dose may be increased gradually up to 40 mg daily in increments of 10 mg. The recommended dose is 40 mg daily. The maximum dose is 60 mg daily. The treatment should last for several months.<\/p>\n\n\n\n
Panic syndrome<\/em><\/p>\n\n\n\nThe starting dose is 10 mg daily. Depending on the treatment response, the dose may be increased gradually up to 40 mg daily in increments of 10 mg. The recommended dose is 40 mg daily. The maximum dose is 60 mg daily. The treatment should last for several months.<\/p>\n\n\n\n
Social phobia<\/em>, generalized anxiety disorder, and post-traumatic<\/em>\u00a0stress disorder<\/p>\n\n\n\nThe recommended dose is 20 mg daily. Depending on the treatment response, the dose may be increased gradually up to 50 mg in increments of 10 mg. The maximum dose is 50 mg daily.<\/p>\n\n\n\n
Use in children and adolescents<\/strong><\/p>\n\n\n\nParoxetine should not be used in children and adolescents under 18 years of age.<\/p>\n\n\n\n
Use in the elderly<\/strong><\/p>\n\n\n\nDepending on the response to treatment, the dose may be increased up to 40 mg daily. The maximum dose is 40 mg daily.<\/p>\n\n\n\n
Severe renal impairment<\/strong><\/p>\n\n\n\nYour doctor will prescribe a dose that is right for you.<\/p>\n\n\n\n
Hepatic impairment<\/strong><\/p>\n\n\n\nYour doctor will prescribe a dose that is right for you.<\/p>\n\n\n\n
Take the medicine with a glass of water, preferably in the morning with a meal. The tablets or tablet halves should be swallowed rather than chewed.<\/p>\n\n\n\n
If you take more Paroxetine Orion than you should<\/h2>\n\n\n\n
If you have ingested too much medicine or if, for example, a child has ingested medicine by mistake, contact a doctor or hospital in Sweden) for risk assessment and advice.<\/p>\n\n\n\n
Symptoms of overdose include vomiting, dilated\u00a0pupils, fever, changes in blood pressure, headache, involuntary muscle contractions, agitation, anxiety, and rapid\u00a0pulse.<\/p>\n\n\n\n
If you forget to take Paroxetine Orion<\/h2>\n\n\n\n
If you forget to take\u00a0Paroxetine\u00a0Orion, skip the missed\u00a0dose\u00a0and take the next\u00a0dose\u00a0at the right time.\u00a0Do not take a double\u00a0dose\u00a0to make up for a forgotten\u00a0dose.<\/p>\n\n\n\n
If you stop taking Paroxetine Orion<\/h2>\n\n\n\n
Do not stop taking Paroxetine Orion without consulting your doctor even if you are feeling well.<\/p>\n\n\n\n
If you suddenly stop after taking this medicine for a long time, you may experience withdrawal symptoms.\u00a0You may feel dizzy, have sensory disturbances (numbness or tingling, so-called\u00a0paresthesia, feeling of electric shock and ringing in the ears), difficulty sleeping (including intense dreams), nausea, diarrhea, headache, rapid and irregular heartbeat (\u00a0palpitations), tremors, increased sweat production, visual disturbances or feeling of upset, anxiety, irritation or confusion about where you are (disorientation).\u00a0These symptoms are mostly mild to moderate and disappear within two weeks.\u00a0For some patients, however, the symptoms become more severe and persist longer.\u00a0The symptoms usually appear within a few days after you stop taking the medicine.\u00a0See \u201cDiscontinuation symptoms upon discontinuation of paroxetine therapy\u201d.<\/p>\n\n\n\n
When stopping treatment with\u00a0Paroxetine\u00a0Orion, your doctor will help you gradually reduce your\u00a0dose\u00a0over some weeks or months to reduce the risk of withdrawal symptoms.\u00a0One way to do this is to gradually reduce your\u00a0dose\u00a0by 10 mg every week.<\/p>\n\n\n\n
If you experience withdrawal symptoms during the tapering period, your doctor may slow down the tapering rate. Contact your doctor if you experience severe withdrawal symptoms when you stop taking Paroxetine Orion. He or she may ask you to start taking the tablets again and then reduce the dose more slowly.<\/p>\n\n\n\n
If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/strong><\/p>\n\n\n\nPossible side effects<\/h2>\n\n\n\n
Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n
You should contact your doctor immediately if you experience symptoms such as:<\/p>\n\n\n\n
- Swelling of the face, swollen tongue and\/or throat and\/or difficulty swallowing or\u00a0hives\u00a0and difficulty breathing (\u00a0angioedema\u00a0)<\/li>
- High fever, muscle cramps, confusion, and anxiety, these symptoms can be signs of so-called “serotonergic syndrome”.<\/li><\/ul>\n\n\n\n
If you have suicidal ideation when you are treated with Paroxetine Orion, especially during the first 2 – 4 weeks, contact your doctor immediately.<\/p>\n\n\n\n
Very common (may affect more than 1 user in 10):<\/em><\/p>\n\n\n\n- nausea<\/li>
- sexual disability.<\/li><\/ul>\n\n\n\n
Common (may affect up to 1 in 10 people):<\/em><\/p>\n\n\n\n- decreased appetite elevated cholesterol levels<\/li>
- drowsiness, insomnia, agitation, abnormal dreams (including nightmares)<\/li>
- headache<\/li>
- dizziness, tremors<\/li>
- concentration difficulties<\/li>
- dimsyn<\/li>
- yawning<\/li>
- constipation, diarrhea, vomiting,\u00a0dry mouth<\/li>
- increased sweat production<\/li>
- weakness (\u00a0asthenia\u00a0), increased body weight.<\/li><\/ul>\n\n\n\n
Uncommon (may affect up to 1 in 100 people):<\/em><\/p>\n\n\n\n- abnormal bleeding, especially in the skin and mucous membranes (including large bruises and unexplained\u00a0vaginal\u00a0bleeding)<\/li>
- confusion, hallucinations<\/li>
- slow and\/or involuntary movements (extrapyramidal disturbances)<\/li>
- fast heartbeat<\/li>
- temporarily raised\u00a0blood pressure\u00a0or temporarily lowered\u00a0blood pressure\u00a0which may make you feel dizzy or faint if you get up suddenly.\u00a0Temporary hypertension or decreased\u00a0blood pressure\u00a0has been reported with paroxetine treatment, usually in patients who already had high\u00a0blood pressure\u00a0(\u00a0hypertension\u00a0) or in patients with anxiety<\/li>
- dilated\u00a0pupil\u00a0is<\/li>
- rash,\u00a0itching<\/li>
- inability to urinate (\u00a0urinary retention\u00a0), involuntary urine leakage (urinary incontinence).<\/li>
- If you have\u00a0diabetes, your blood sugar levels may be affected if you take\u00a0Paroxetine\u00a0Orion.\u00a0Talk to your doctor about adjusting the\u00a0dose\u00a0of one of your\u00a0insulin\u00a0or\u00a0diabetes\u00a0medicines.<\/li><\/ul>\n\n\n\n
Rare (may affect up to 1 in 1,000 people):<\/em><\/p>\n\n\n\n- the decreased sodium level in the blood (\u00a0hyponatremia\u00a0).\u00a0Hyponatremia\u00a0has been reported mainly in elderly patients and some cases is due to SIADH (inappropriate\u00a0ADH\u00a0secretion syndrome)<\/li>
- manic reactions, anxiety, feeling detached (depersonalization), panic attacks, restlessness, and feeling unable to stand or sit still (see section 2 \u201cWarnings and caution\u201d).\u00a0These symptoms may also be due to the underlying disease<\/li>
- seizures, restless legs syndrome<\/li>
- slow heart rate<\/li>
- elevated liver enzyme levels<\/li>
- joint pain, muscle pain<\/li>
- hyperprolactinemia\u00a0(abnormally high blood levels of the\u00a0hormone\u00a0et\u00a0prolactin\u00a0) \/ secretion from the breasts.<\/li>
- menstrual disorders (including heavy or irregular menstrual bleeding, menstrual bleeding, and absence or delayed menstruation.<\/li><\/ul>\n\n\n\n
Very rare (may affect up to 1 in 10,000 people):<\/em><\/p>\n\n\n\n- lack of\u00a0platelets<\/li>
- allergic reactions, which may be severe for\u00a0Paroxetine\u00a0Orion, with\u00a0hives\u00a0and swelling of the eyelids, face, lips, tongue, or throat with difficulty breathing or difficulty swallowing (\u00a0angioedema\u00a0)<\/li>
- the feeling of weakness or dizziness leading to collapse or unconsciousness, contact your doctor or see a hospital immediately<\/li>
- increased\u00a0secretion\u00a0of\u00a0antidiuretic hormone\u00a0(inappropriate\u00a0ADH\u00a0secretion syndrome), leading to\u00a0hyponatremia\u00a0with symptoms such as headache, nausea, and vomiting<\/li>
- serotonergic syndrome (symptoms may include restlessness, confusion, increased sweat production, hallucinations, increased reflexes, muscle cramps, chills, rapid heartbeat, and tremors)<\/li>
- acute\u00a0glaucoma\u00a0(\u00a0glaucoma, eye disease that damages\u00a0the optic nerve\u00a0)<\/li>
- gastrointestinal bleeding<\/li>
- liver disease (such as\u00a0hepatitis\u00a0), in some cases with jaundice and\/or liver failure).\u00a0Since\u00a0paroxetine\u00a0was first approved, reports of liver disease (such as hepatitis,\u00a0in some cases with jaundice and\/or hepatic failure) have been reported in very rare cases.\u00a0Discontinuation\u00a0of\u00a0paroxetine\u00a0should be considered if a persistent increase in hepatic function values \u200b\u200bis observed.<\/li>
- severe skin side effects (including erythema multiforme,\u00a0Stevens-Johnson\u00a0syndrome and\u00a0toxic epidermal necrolysis,<\/li>
- increased sensitivity to sunlight<\/li>
- a prolonged\u00a0erection\u00a0(priapism)<\/li>
- swelling due to fluid retention.<\/li><\/ul>\n\n\n\n
Has been reported (occurs in an unknown number of users):<\/em><\/p>\n\n\n\n- thoughts of self-harm or suicide.\u00a0Suicidal ideation or suicidal ideation has been reported during treatment with\u00a0paroxetine\u00a0or early after\u00a0discontinuation\u00a0of treatment (see section 2 \u201cWarnings and precautions\u201d).<\/li>
- Some patients have experienced wheezing, hissing, whistling, ringing, or other stubborn sounds (\u00a0tinnitus\u00a0) when taking\u00a0Paroxetine\u00a0Orion.<\/li>
- aggression<\/li>
- gnashing of teeth<\/li>
- inflammation\u00a0of the colon (which causes diarrhea).<\/li>
- severe vaginal bleeding shortly after delivery (\u00a0postpartum hemorrhage), see \u201cPregnancy\u201d in section 2 for more information.<\/li><\/ul>\n\n\n\n
Withdrawal symptoms when paroxetine is discontinued<\/strong><\/p>\n\n\n\nCommon:<\/em> dizziness, sensory disturbances, ringing in the ears ( tinnitus ), sleep disturbances, anxiety, headache.<\/p>\n\n\n\nUncommon:<\/em> agitation, nausea, tremors, confusion, increased sweat production, emotional imbalance, visual disturbances, palpitations, diarrhea, irritability.<\/p>\n\n\n\nSee “If you stop taking Paroxetine Orion”.<\/p>\n\n\n\n
An increased risk of bone fractures has been seen in patients taking this type of drug.<\/p>\n\n\n\n
Reporting of side effects ar<\/strong><\/p>\n\n\n\nIf you get\u00a0any side effects, talk to your doctor, pharmacist, or nurse.\u00a0This also applies to any\u00a0side effects\u00a0not mentioned in this information.\u00a0You can also report side effects directly via:<\/p>\n\n\n\n
By reporting\u00a0side effects, you can help increase drug safety information.<\/p>\n\n\n\n
How to store Paroxetine Orion<\/h2>\n\n\n\n
Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n
Do not use this medicine after the expiry date which is stated on the carton and blister. The expiration date is the last day of the specified month.<\/p>\n\n\n\n
This medicine does not require any special storage instructions.<\/p>\n\n\n\n
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.<\/p>\n\n\n\n
Contents of the pack and other information<\/h2>\n\n\n\nContent declaration<\/h2>\n\n\n\n- The active substance is\u00a0paroxetine.<\/li><\/ul>\n\n\n\n
Each film-coated tablet contains 20 mg\u00a0of paroxetine\u00a0(as paroxetine hydrochloride hemihydrate).<\/p>\n\n\n\n
The other ingredients in the tablet core are calcium hydrogen phosphate dihydrate, calcium hydrogen phosphate,\u00a0lactose monohydrate, sodium starch glycolate (type A), and magnesium stearate<\/p>\n\n\n\n
The other ingredients in the film coating are titanium dioxide (E171), hypromellose, macrogol 400, and polysorbate 80.<\/p>\n\n\n\n
What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n
White to off-white, film-coated capsule-shaped, biconvex tablets imprinted with \u201c56\u201d on one side and \u201cC\u201d with a deep incision on the other side.\u00a0The tablet can be divided into two equal\u00a0doses.<\/p>\n\n\n\n
Pack sizes:<\/p>\n\n\n\n
20, 30, 60, and 100 tablets.<\/p>\n\n\n\n
Not all pack sizes may be marketed.<\/p>\n\n\n\n
Marketing Authorisation Holder<\/h2>\n\n\n\n
Orion Corporation<\/p>\n\n\n\n
Orionintie 1<\/p>\n\n\n\n
FI-02200 Espoo<\/p>\n\n\n\n
Finland<\/p>\n\n\n\n
Manufacturer<\/strong><\/p>\n\n\n\nOrion Corporation, Orion Pharma<\/p>\n\n\n\n
Orionintie 1<\/p>\n\n\n\n
FI-02200 Espoo<\/p>\n\n\n\n
Finland<\/p>\n","protected":false},"excerpt":{"rendered":"
Paroxetine Orion belongs to a group of antidepressants called selective serotonin reuptake inhibitors ( SSRIs ).<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,18527],"tags":[21040,21052,21055,21056,21044,21043,21041,21053,21042,21054],"class_list":["post-20544","post","type-post","status-publish","format-standard","hentry","category-medicines","category-p","tag-paroxetine","tag-paroxetine-orion","tag-paroxetine-orion-side-effects","tag-paroxetine-orion-tablet","tag-paroxetine-side-effects","tag-paroxetine-tablet","tag-what-is-paroxetine","tag-what-is-paroxetine-orion","tag-what-paroxetine-is-used-for","tag-what-paroxetine-orion-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/20544","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=20544"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/20544\/revisions"}],"predecessor-version":[{"id":20602,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/20544\/revisions\/20602"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=20544"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=20544"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=20544"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}