{"id":20471,"date":"2022-04-05T07:45:36","date_gmt":"2022-04-05T07:45:36","guid":{"rendered":"https:\/\/zeepedia.com\/?p=20471"},"modified":"2022-04-06T10:26:44","modified_gmt":"2022-04-06T10:26:44","slug":"paracetamol-codeine-evolan","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/paracetamol-codeine-evolan\/","title":{"rendered":"Paracetamol \/ Codeine Evolan | Paracetamol and codeine phosphate hemihydrate | uses, dose and side effects"},"content":{"rendered":"\n<p>500 mg \/ 30 mg&nbsp;effervescent&nbsp;tablet<br>paracetamol&nbsp;and <a href=\"https:\/\/zeepedia.com\/medical\/medicines\/treo-comp\/\">codeine phosphate hemihydrate<\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Paracetamol \/ Codeine Evolan is and what it is used for<\/h2>\n\n\n\n<p>Paracetamol \/ Codeine Evolan contains two painkillers (\u00a0paracetamol\u00a0and\u00a0codeine\u00a0), which work in different ways.\u00a0Paracetamol\u00a0has both analgesic and antipyretic effects.\u00a0Codeine\u00a0belongs to a group of drugs called opioid analgesics that work by relieving pain.\u00a0It can be used alone or in combination with other painkillers such as\u00a0paracetamol.<\/p>\n\n\n\n<p>Paracetamol \/ Codeine Evolan is used for aches and pains of various kinds.<\/p>\n\n\n\n<p>Paracetamol\u00a0and\u00a0codeine\u00a0contained in Paracetamol \/ Codeine Evolan may also be approved for the treatment of other conditions not mentioned in this product information.\u00a0Ask your doctor, pharmacist, or other healthcare professionals if you have any further questions, and always follow their instructions.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before you use Paracetamol \/ Codeine Evolan<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Paracetamol \/ Codeine Evolan<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to\u00a0paracetamol,\u00a0codeine,\u00a0or any of the other ingredients of this medicine (listed in section 6)<\/li><li>if you know that you are very fast converting\u00a0codeine\u00a0to morphine<\/li><li>if you are breast-feeding<\/li><li>if you suffer from biliary tract problems.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Never take more Paracetamol \/ Codeine Evolan tablets than those listed in section 3 \u201cHow to use Paracetamol \/ Codeine Evolan\u201d.\u00a0If you are taking other painkillers that contain\u00a0paracetamol, do not use Paracetamol \/ Codeine Evolan without first talking to a doctor or pharmacist.<\/li><li>Higher\u00a0doses\u00a0than those recommended do not provide better pain relief but instead entail a risk of impaired respiratory function and very serious liver damage.\u00a0The symptoms of liver damage usually come only after a few days.\u00a0It is therefore important that you contact a doctor as soon as possible if you have taken too large a\u00a0dose.\u00a0The risk of this type of liver damage increases with alcohol abuse.<\/li><\/ul>\n\n\n\n<p>Talk to your doctor before using Paracetamol \/ Codeine Evolan:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you have\u00a0asthma.\u00a0Take special care with Paracetamol \/ Codeine Evolan if you have\u00a0asthma\u00a0and at the same time are hypersensitive to\u00a0<a href=\"https:\/\/zeepedia.com\/medical\/medicines\/tiplo-citrus\/\">acetylsalicylic acid<\/a>.<\/li><li>if you have alcohol problems.<\/li><li>if you have liver damage.<\/li><li>if you have a serious\u00a0infection\u00a0such as blood poisoning, this can increase the risk of so-called metabolic\u00a0acidosis.\u00a0Signs of metabolic\u00a0acidosis\u00a0include difficulty breathing (deep inhalation and rapid exhalation), nausea, and vomiting.\u00a0Contact a doctor immediately if you get a combination of these symptoms.<\/li><\/ul>\n\n\n\n<p>Do not use Paracetamol \/ Codeine Evolan with alcohol.<\/p>\n\n\n\n<p>If you use Paracetamol \/ Codeine Evolan for a long time, there is a risk of developing an addiction.<\/p>\n\n\n\n<p>Due to their sodium content,&nbsp;effervescent tablets&nbsp;are not suitable for people on a low-salt diet.<\/p>\n\n\n\n<p>Codeine\u00a0is converted to morphine in the liver by an\u00a0enzyme.\u00a0It is morphine that provides pain relief.\u00a0Some people have different variants of this\u00a0enzyme\u00a0that allow them to be affected in different ways.\u00a0Some people cannot form morphine or it is formed in very small amounts, which means that you do not get enough pain relief.\u00a0Other people have an increased risk of getting serious\u00a0side effects\u00a0because they can produce a very large amount of morphine.\u00a0If you get any of the following\u00a0side effects, you must stop taking this medicine and contact a doctor immediately: slow or shallow breathing, confusion, drowsiness, small\u00a0pupils, nausea or vomiting, constipation, and loss of appetite.<\/p>\n\n\n\n<p><strong>Children and young people<\/strong><\/p>\n\n\n\n<p>Paracetamol \/ Codeine Evolan is not approved for the treatment of children and adolescents under 18 years of age.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Use of other medicines<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.<\/p>\n\n\n\n<p>Some medicines \/ herbal medicines can affect or be affected by treatment with Paracetamol \/ Codeine Evolan, for example:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Quinidine\u00a0(medicine for irregular heartbeat)<\/li><li>Neuroleptics\u00a0(medicines for mental illness)<\/li><li>Antidepressants<\/li><li>Warfarin\u00a0(a blood thinner).\u00a0Contact your doctor if you take more than 2 tablets of Paracetamol \/ Codeine Evolan per day for 5 consecutive days.\u00a0There is a risk that the effect of\u00a0warfarin will\u00a0be affected.<\/li><li>Probenecid (medicine for\u00a0gout\u00a0)<\/li><li>Certain medicines for\u00a0epilepsy\u00a0(\u00a0phenytoin, phenobarbital, and carbamazepine)<\/li><li>Rifampicin (a medicine used to\u00a0treat tuberculosis\u00a0)<\/li><li>Cholestyramine (medicine for high blood fats).\u00a0Paracetamol \/ Codeine Evolan and cholestyramine should be taken at least 1 hour apart.<\/li><li>Chloramphenicol for\u00a0injection\u00a0(medicine for bacterial infections).\u00a0However, chloramphenicol against\u00a0infection\u00a0in your eye can be used.<\/li><li>St. John&#8217;s wort extract (included in some (traditional) herbal and herbal remedies)<\/li><li>Metoclopramide (nausea medicine).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<\/p>\n\n\n\n<p>Taking Paracetamol \/ Codeine Evolan should be avoided by women who are planning to become pregnant or are pregnant.\u00a0Treatment during any part of the pregnancy should only be done after a doctor&#8217;s\u00a0prescription.<\/p>\n\n\n\n<p>Do not take Paracetamol \/ Codeine Evolan if you are breastfeeding.\u00a0Codeine\u00a0and morphine pass into breast milk.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Paracetamol \/ Codeine Evolan can impair the ability to react and make you tired and drowsy, which you should keep in mind at times when sharpened attention is required, for example when driving a car and precision work.<br>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects.\u00a0Descriptions of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Paracetamol \/ Codeine Evolan contains lactose, sodium and sorbitol<\/h2>\n\n\n\n<p>Among the other ingredients in Paracetamol \/ Codeine Evolan, an effervescent\u00a0tablet\u00a0is a sugar called\u00a0lactose.\u00a0If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.<\/p>\n\n\n\n<p>This medicine contains 316 mg\u00a0sodium\u00a0(the main ingredient in table salt\/table salt) per\u00a0effervescent tablet.\u00a0This corresponds to 16% of the maximum recommended daily\u00a0sodium\u00a0intake for adults.\u00a0Consult your doctor or pharmacist if you need 1 or more\u00a0effervescent tablets\u00a0daily for an extended period, especially if you have been prescribed a low-salt (sodium-poor) diet.<\/p>\n\n\n\n<p>This medicine contains 80 mg sorbitol per\u00a0effervescent tablet.\u00a0Sorbitol is a source of fructose.\u00a0If you (or your child) cannot tolerate certain sugars, or if you (or your child) have been diagnosed with\u00a0hereditary<\/p>\n\n\n\n<p>fructose intolerance, a rare, inherited disease that prevents you from breaking down fructose, talk to your doctor before using this medicine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to use Paracetamol \/ Codeine Evolan<\/h2>\n\n\n\n<p>Always use this medicine exactly as your doctor or pharmacist has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p><em>Note!&nbsp;Higher&nbsp;doses&nbsp;than those recommended can pose serious risks.<\/em><\/p>\n\n\n\n<p>The recommended\u00a0dose\u00a0for adults: 1-2 effervescent tablets 1-4 times a day.\u00a0Take a maximum of 8 tablets per day.<\/p>\n\n\n\n<p><strong>Use for children and adolescents<\/strong><\/p>\n\n\n\n<p>Paracetamol\/codeine Evolan is not approved for the treatment of children and adolescents under 18 years of age.<\/p>\n\n\n\n<p>Dissolve the&nbsp;effervescent tablets&nbsp;in a glass of water.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you use more Paracetamol \/ Codeine Evolan than you should &nbsp;<\/h2>\n\n\n\n<p>If you have ingested too much medicine or if, for example, a child has accidentally ingested the medicine, always contact a doctor or hospital for risk assessment and advice.\u00a0<em>There is a risk of liver damage even if you feel well.\u00a0<\/em>To prevent possible liver damage, the antidote must be inserted by a doctor as early as possible.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p>Stop taking Paracetamol \/ Codeine Evolan and contact a doctor immediately if you get any of the following symptoms (&nbsp;angioedema&nbsp;).&nbsp;A rare side effect&nbsp;<em>(may affect up to 1 in 1,000 people).<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>swelling of the face, tongue, or throat<\/li><li>difficulty swallowing<\/li><li>hives,\u00a0and difficulty breathing.<\/li><\/ul>\n\n\n\n<p><em>Common (may affect up to 1 in 10 people)<\/em>&nbsp;: Fatigue, nausea, constipation.<\/p>\n\n\n\n<p><em>Uncommon (may affect up to 1 in 100 people)<\/em>: Bile duct cramps may occur in people who are prone to this.<\/p>\n\n\n\n<p><em>Rare (may affect up to 1 in 1,000 people)<\/em>: Skin rash, liver damage, impaired kidney function, allergic reactions such as\u00a0hives, swelling of the face, lips, tongue, or throat, sometimes with shortness of breath or difficulty swallowing (\u00a0angioedema\u00a0).<\/p>\n\n\n\n<p><em>Very rare (may affect up to 1 in 10,000 people)<\/em>:\u00a0Inflammation\u00a0of the pancreas.<\/p>\n\n\n\n<p>Very rare cases of severe skin reactions have been reported.<\/p>\n\n\n\n<p>In case of allergic reactions, you should stop taking Paracetamol \/ Codeine Evolan and consult a doctor.<\/p>\n\n\n\n<p>If you use Paracetamol \/ Codeine Evolan for a long time, the risk of kidney damage can not be completely ruled out.<\/p>\n\n\n\n<p>Liver damage can occur with the use of&nbsp;paracetamol&nbsp;in connection with alcohol abuse.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Paracetamol \/ Codeine Evolan<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children and adolescents.<\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the carton after EXP.\u00a0data.\u00a0The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>Store in the original package.&nbsp;Close the tube tightly.&nbsp;Moisture sensitive.<\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the pack and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substances are\u00a0paracetamol\u00a0500 mg and codeine phosphate hemihydrate 30 mg per tablet.<\/li><li>The other ingredients are povidone, sodium bicarbonate, anhydrous citric acid, sorbitol,\u00a0lactose monohydrate, saccharin sodium,\u00a0ascorbic acid, L-leucine, flavoring (lemon).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>Effervescent tablet&nbsp;one is white, round, flat with a break notch on one side.&nbsp;Diameter 23 mm.<\/p>\n\n\n\n<p>Plastic pipe with desiccant in the plastic lid.&nbsp;Pack sizes: 20 tablets and 100 (5 \u00d7 20) tablets.<\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorisation Holder:<\/h2>\n\n\n\n<p>Evolan Pharma AB<br>Box 120<br>182 12 Danderyd<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Manufacturer:<\/h2>\n\n\n\n<p>SMB Technology SA<br>Rue du Parc Industriel 39<br>6900 Marche-en-Famenne<br>Belgium<\/p>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Paracetamol \/ Codeine Evolan contains two painkillers ( paracetamol and codeine ), which work in different ways. Paracetamol has both analgesic and antipyretic effects. Codeine belongs to a group of drugs called opioid analgesics that work by relieving pain. It can be used alone or in combination with other painkillers such as paracetamol .<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,18527],"tags":[20967,20970,20971,10782,10785,2363,2366,5315,20969,10784,20968,10783,5314,10731],"class_list":["post-20471","post","type-post","status-publish","format-standard","hentry","category-medicines","category-p","tag-codeine-evolan","tag-codeine-evolan-side-effects","tag-codeine-evolan-tablet","tag-codeine-phosphate-hemihydrate","tag-codeine-phosphate-hemihydrate-tablet","tag-paracetamol","tag-paracetamol-side-effects","tag-paracetamol-tablet","tag-what-codeine-evolan-is-used-for","tag-what-codeine-phosphate-hemihydrate-is-used-for","tag-what-is-codeine-evolan","tag-what-is-codeine-phosphate-hemihydrate","tag-what-is-paracetamol","tag-what-paracetamol-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/20471","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=20471"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/20471\/revisions"}],"predecessor-version":[{"id":20535,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/20471\/revisions\/20535"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=20471"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=20471"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=20471"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}