{"id":20335,"date":"2022-03-30T14:28:11","date_gmt":"2022-03-30T14:28:11","guid":{"rendered":"https:\/\/zeepedia.com\/?p=20335"},"modified":"2022-04-01T10:44:08","modified_gmt":"2022-04-01T10:44:08","slug":"panocod","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/panocod\/","title":{"rendered":"Panocod &#8211; Paracetamol \/ Codeine uses, dose and side effects"},"content":{"rendered":"\n<p>500 mg \/ 30 mg&nbsp;tablets or&nbsp;effervescent tablets&nbsp;are<br>paracetamol \/ codeine<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Panocod is and what it is used for<\/h2>\n\n\n\n<p>Panocod contains&nbsp;paracetamol&nbsp;and&nbsp;codeine&nbsp;.&nbsp;Paracetamol&nbsp;has a pain-relieving and antipyretic effect.<\/p>\n\n\n\n<p>Codeine\u00a0belongs to a group of drugs called opioid analgesics that work by relieving pain.\u00a0It can be used alone or in combination with other painkillers such as\u00a0paracetamol.<\/p>\n\n\n\n<p>Panocod tablets and&nbsp;effervescent tablets&nbsp;are used for aches and pains of various kinds in adults.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before taking Panocod<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not take Panocod:<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to\u00a0paracetamol,\u00a0codeine,\u00a0or any of the other ingredients of this medicine (listed in section 6).<\/li><li>if you suffer from biliary tract problems<\/li><li>if you have severe hepatic impairment<\/li><li>if you have difficulty breathing<\/li><li>if you are about to give birth or if there is a risk of premature birth<\/li><li>if you are breast-feeding<\/li><li>if you know that your body very quickly converts\u00a0codeine\u00a0to morphine<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before using Panocod:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you have\u00a0asthma<\/li><li>if you are\u00a0taking benzodiazepines\u00a0(sedatives, hypnotics, and medicines used to\u00a0treat epilepsy\u00a0)<\/li><li>if you are hypersensitive to certain medicines for fever or pain (\u00a0<a href=\"https:\/\/zeepedia.com\/medical\/medicines\/tiplo-citrus\/\">acetylsalicylic acid<\/a>, non-steroidal anti-inflammatory drugs,\u00a0NSAIDs\u00a0)<\/li><li>if you have impaired liver function including if you have a disease called Gilbert&#8217;s syndrome<\/li><li>if you have impaired kidney function<\/li><li>if you are older<\/li><li>if you have\u00a0anemia<\/li><li>if you are dehydrated or malnourished<\/li><li>if you have long-term (chronic) alcohol intake, including if you have recently stopped drinking alcohol<\/li><li>if you are deficient in the\u00a0enzyme\u00a0glucose &#8211;\u00a06\u00a0-phosphate dehydrogenase<\/li><li>if you have prostate enlargement or urethral stricture<\/li><li>if you have any\u00a0inflammatory\u00a0bowel disease<\/li><li>if you have a disease that involves an impaired respiratory function<\/li><li>if you have a serious\u00a0infection\u00a0such as blood poisoning, this can increase the risk of so-called metabolic\u00a0acidosis.\u00a0Signs of metabolic\u00a0acidosis\u00a0include difficulty breathing, nausea, and vomiting.\u00a0Contact a doctor immediately if you get a combination of these symptoms.<\/li><\/ul>\n\n\n\n<p>Never take more Panocod than is stated in the dosing instructions.\u00a0If you are taking other painkillers that contain\u00a0paracetamol, do not use Panocod without first talking to your doctor or pharmacist.<\/p>\n\n\n\n<p><em>Higher\u00a0doses\u00a0than those recommended do not provide better pain relief but instead entail a risk of impaired respiratory function and very serious liver damage.\u00a0<\/em>The symptoms of liver damage usually come only after a few days.\u00a0Therefore, you must contact a doctor as soon as possible if you have taken too large a\u00a0dose.<\/p>\n\n\n\n<p>Concomitant use of alcohol should be avoided, as the combination can cause drowsiness, impaired respiratory function,\u00a0coma,\u00a0and even death.\u00a0See also heading &#8220;Panocod with alcohol&#8221;.<\/p>\n\n\n\n<p>The risk of this type of liver damage increases with alcohol abuse.&nbsp;Do not use Panocod without your doctor&#8217;s&nbsp;prescription&nbsp;if you have alcohol problems or liver damage.&nbsp;The intoxicating effect of alcohol does not increase with the addition of Panocod.&nbsp;Do not use Panocod with alcohol.<\/p>\n\n\n\n<p>Liver damage can occur even at lower\u00a0doses, after a short period of treatment, and when there are no other problems with the liver.<\/p>\n\n\n\n<p>Codeine\u00a0is converted to morphine in the liver by an\u00a0enzyme.\u00a0It is morphine that provides pain relief.\u00a0Some people have different variants of this\u00a0enzyme\u00a0that allow them to be affected in different ways.\u00a0Some people cannot form morphine or it is formed in very small amounts, which means that you do not get enough pain relief.\u00a0Other people have an increased risk of getting serious\u00a0side effects, as they can produce a very large amount of morphine.\u00a0If you get any of the following\u00a0side effects, you must stop taking this medicine and contact a doctor immediately: slow or shallow breathing, confusion, drowsiness, small\u00a0pupils, nausea or vomiting, constipation, and loss of appetite.<\/p>\n\n\n\n<p>If you use Panocod for a long time, there is a risk of developing an addiction.<\/p>\n\n\n\n<p>The risk of getting used to&nbsp;codeine&nbsp;compared to morphine is small but should not be overlooked.<\/p>\n\n\n\n<p>Prolonged use of painkillers for headaches can worsen the headache.&nbsp;If you have or think you may have such a headache, you should seek medical advice and stop treatment.<\/p>\n\n\n\n<p>Due to its sodium salt content, Panocod effervescent\u00a0tablets\u00a0should not be used if a low-salt diet is prescribed and may also be unsuitable for those with high\u00a0blood pressure\u00a0or poor heart\/kidney function.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children<\/h2>\n\n\n\n<p>Panocod is not approved for the treatment of children under 18 years.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Panocod<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.<\/p>\n\n\n\n<p>The treatment can be affected if this medicine is taken at the same time as certain other medicines \/ herbal medicines.\u00a0The treating physician, therefore, needs to know about other concomitant medications.<\/p>\n\n\n\n<p>Concomitant use of Panocod with certain medicines increases the risk of drowsiness, difficulty breathing (\u00a0respiratory depression\u00a0),\u00a0coma\u00a0and may be life-threatening.\u00a0Examples of these drugs are:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>other strong painkillers<\/li><li>sedatives, hypnotics, and antiepileptic\u00a0drugs\u00a0(eg certain\u00a0antihistamines,\u00a0benzodiazepines,\u00a0and\u00a0barbiturates\u00a0)<\/li><li>anesthetics for anesthesia before e.g.\u00a0an operation<\/li><li>certain medicines for mental illness (phenothiazines)<\/li><li>muscle relaxants<\/li><\/ul>\n\n\n\n<p>The following medicines may affect or be affected by treatment with Panocod:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Quinidine\u00a0(used to treat heart rhythm disorders)<\/li><li>Neuroleptics\u00a0(which are a group of drugs for certain mental illnesses)<\/li><li>Antidepressants (\u00a0fluoxetine,\u00a0paroxetine, bupropion) (used for depression)<\/li><li>Cinacalcet (a drug for diseases of the parathyroid gland)<\/li><li>Warfarin\u00a0and other antivitamin-K drugs (blood thinners).\u00a0Contact your doctor if you take more than 2 effervescent tablets\/tablets of Panocod per day for 5 consecutive days.\u00a0There is a risk that the effect of\u00a0warfarin will\u00a0be affected.<\/li><li>Chloramphenicol for\u00a0injection\u00a0(medicine for bacterial infections).\u00a0However, chloramphenicol against\u00a0infection\u00a0in your eye can be used.<\/li><li>Probenecid (used for\u00a0gout\u00a0)<\/li><li>Some medicines for\u00a0epilepsy\u00a0(\u00a0phenytoin, phenobarbital, carbamazepine, <a href=\"https:\/\/zeepedia.com\/medical\/medicines\/topiramate-1a-pharma\/\">topiramate<\/a>)<\/li><li>Rifampicin (a medicine used to\u00a0treat tuberculosis\u00a0)<\/li><li>Cholestyramine (medicines for high blood fats), Panocod, and cholestyramine should be taken at least one hour apart.<\/li><li>St. John&#8217;s wort extract (included with some herbal remedies)<\/li><li>Metoclopramide, domperidone (anti-nausea medicine)<\/li><li>Flucloxacillin (anti-infective\u00a0drug )<\/li><li>Cough suppressants b<\/li><li>Medicines for high\u00a0blood pressure<\/li><li>Tricyclic antidepressants (imipramine, amitriptyline)<\/li><li>MAO inhibitors\u00a0(antidepressants, such as <a href=\"https:\/\/zeepedia.com\/medical\/medicines\/tranylcypromine-glenmark\/\">tranylcypromine<\/a>).\u00a0Panocod should not be taken within two weeks after stopping treatment with\u00a0an MAOI.<\/li><li>Medicines for diarrhea.<\/li><li>Buprenorphine,\u00a0methadone\u00a0(medicines used to treat pain or to treat patients who have developed an\u00a0opioid\u00a0addiction )<\/li><li>Naltrexone (used as adjunctive therapy in alcohol dependence or medicines for obesity, for example).<\/li><li>Some so-called chelating resin.\u00a0Panocod and chelating resin should be taken at least two hours apart.<\/li><\/ul>\n\n\n\n<p>Do not take other medicines containing paracetamol at the same time!<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Panocod with alcohol<\/h2>\n\n\n\n<p>Concomitant use of alcohol should be avoided due to the risk of impaired respiratory function.&nbsp;See also section &#8220;Warnings and precautions&#8221;.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<\/p>\n\n\n\n<p><em>Pregnancy<\/em><\/p>\n\n\n\n<p>If necessary, Panocod can be used during pregnancy.\u00a0However, you should use the lowest possible\u00a0dose\u00a0that relieves your pain and\/or fever and use it for the shortest possible time.\u00a0Contact your doctor or midwife if the pain and\/or fever do not decrease or if you need to take the medicine more often.\u00a0Panocod should be avoided during the last three months of pregnancy and childbirth.<\/p>\n\n\n\n<p><em>Breast-feeding<\/em><\/p>\n\n\n\n<p>Do not take Panocod if you are breastfeeding.\u00a0Codeine\u00a0and morphine pass into breast milk.\u00a0<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>During treatment with Panocod, the ability to react may be reduced, and you may become tired and drowsy, which should be borne in mind at times when sharper attention is required, e.g.&nbsp;while driving and precision work.<\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened vigilance.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects.\u00a0Descriptions of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Panocod effervescent tablets contain sorbitol<\/h2>\n\n\n\n<p>This medicine contains 50 mg of sorbitol in each\u00a0effervescent tablet.<br>Sorbitol is a source of fructose.\u00a0If you have been told by your doctor that you have an intolerance to some sugars, or have been diagnosed with\u00a0hereditary\u00a0fructose intolerance, a rare, inherited disease that prevents you from breaking down fructose, talk to your doctor before using this medicine.<\/p>\n\n\n\n<p><strong>Panocod tablets and\u00a0effervescent tablets\u00a0contain sodium:<\/strong><br><br><em>Panocod tablets:<\/em>\u00a0This medicine contains less than 1 mmol (23 mg)\u00a0sodium\u00a0per tablet, ie it is essentially &#8216;sodium-free&#8217;.<br><br><em>Panocod effervescent tablets:<\/em>\u00a0Each\u00a0effervescent tablet\u00a0contains 388 mg of\u00a0sodium\u00a0(the main ingredient in table salt\/table salt).\u00a0The maximum daily dose (8 effervescent tablets) is 155% of the maximum recommended daily\u00a0sodium\u00a0intake for adults.\u00a0Consult your doctor or pharmacist if you need 2 or more\u00a0effervescent tablets\u00a0daily for a long period, especially if you have been prescribed a low-salt (sodium-poor) diet.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to take Panocod<\/h2>\n\n\n\n<p>Always take this medicine exactly as your doctor or pharmacist has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p><em>Note!&nbsp;<\/em><em>Higher&nbsp;doses&nbsp;than those recommended can pose serious risks.<\/em><\/p>\n\n\n\n<p>Dose&nbsp;one is determined by the doctor, who adjusts it individually for you.<\/p>\n\n\n\n<p><em>The usual&nbsp;dose&nbsp;for adults<\/em>&nbsp;is 1-2 tablets or&nbsp;effervescent tablets&nbsp;1-4 times daily, a maximum of 8 tablets or&nbsp;effervescent tablets&nbsp;per day.<\/p>\n\n\n\n<p>Effervescent tablet&nbsp;one is dissolved in half a glass of water.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you take more Panocod than you should<\/h2>\n\n\n\n<p>If you have ingested too much medicine or if e.g.\u00a0a child ingested the medicine by mistake, contact a doctor or hospital for risk assessment and advice.<\/p>\n\n\n\n<p>In case of severe overdose, the hospital should be contacted\u00a0immediately\u00a0(risk of liver damage).\u00a0There is a risk of liver damage even if you feel well.\u00a0An antidote must be inserted by a doctor as early as possible if any liver damage is to be prevented.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to take Panocod<\/h2>\n\n\n\n<p>Do not take a double&nbsp;dose&nbsp;to make up for a forgotten tablet.<\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<br><br><strong>Stop taking Panocod and contact a doctor immediately if you get any of the following symptoms:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Swelling of the face, tongue, or throat;\u00a0difficulty swallowing;\u00a0hives\u00a0and difficulty breathing.\u00a0This may be a sign of\u00a0angioedema\u00a0occurring in up to 1 in 1000 users<\/li><li>An\u00a0infection\u00a0with symptoms such as fever with severely deteriorating general condition or fever with local infection symptoms such as sore throat\/throat\/mouth or difficulty urinating.\u00a0This may indicate a lack of\u00a0white blood cells\u00a0(\u00a0agranulocytosis\u00a0) which occurs in an unknown number of users.<\/li><\/ul>\n\n\n\n<p><em>Common (may affect up to 1 in 10 people):<\/em>&nbsp;Fatigue, nausea, constipation.<\/p>\n\n\n\n<p><em>Uncommon (may affect up to 1 in 100&nbsp;<\/em><em>people&nbsp;<\/em><em>):<\/em>&nbsp;Bile duct cramps may occur in people who are prone to this.<\/p>\n\n\n\n<p><em>Rare (may affect up to 1 in 1,000&nbsp;<\/em><em>people&nbsp;<\/em><em>):<\/em>&nbsp;Skin rash, liver damage, renal impairment.<\/p>\n\n\n\n<p><em>Very rare (may affect up to 1 in 10,000 people\u00a0)<\/em>:\u00a0Inflammation\u00a0of the pancreas, allergic shock (anaphylactic\u00a0shock\u00a0), decreased\u00a0platelet count\u00a0(\u00a0thrombocytopenia\u00a0), decrease in\u00a0white blood cell count\u00a0(\u00a0leukopenia,\u00a0neutropenia\u00a0), severe skin reactions.<\/p>\n\n\n\n<p><em>Has been reported (\u00a0occurs in an unknown number of users\u00a0):\u00a0<\/em>Inflammation\u00a0of the liver that can lead to liver failure, respiratory cramps, hypersensitivity, confusion, feeling of discomfort or sadness (\u00a0dysphoria\u00a0), agitation, risk of dependence on the drug with long-term use, seizures, headache, drowsiness, dizziness, decreased consciousness (\u00a0sedation\u00a0),\u00a0pupil contraction\u00a0(\u00a0miosis\u00a0), difficulty breathing, vomiting,\u00a0dry mouth,\u00a0itching, difficulty urinating.<\/p>\n\n\n\n<p>Severe&nbsp;skin&nbsp;reactions have been reported in very rare cases.<\/p>\n\n\n\n<p>Liver damage when using&nbsp;paracetamol&nbsp;has occurred in connection with alcohol abuse.&nbsp;With long-term treatment, the risk of kidney damage can not be completely ruled out.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Panocod<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Effervescent&nbsp;tablets should be stored in the original packaging.&nbsp;Moisture sensitive.<\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the carton after EXP.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the pack and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<p><em>Panocod tablets:<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substances are\u00a0paracetamol\u00a0500 mg and\u00a0codeine\u00a030 mg per tablet.<\/li><li>The other ingredients are stearic acid, magnesium stearate, polyvidone, microcrystalline cellulose,\u00a0starch, talc, potassium sorbate, corn starch, and croscarmellose sodium.<\/li><\/ul>\n\n\n\n<p><em>Panocod effervescent tablets:<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substances are\u00a0paracetamol\u00a0500 mg and\u00a0codeine\u00a030 mg per\u00a0effervescent tablet.<\/li><li>The other ingredients are sorbitol, saccharin sodium, citric acid, sodium bicarbonate, sodium lauryl sulfate, sodium carbonate (anhydrous), polyvidone, and dimethicone.<\/li><\/ul>\n\n\n\n<p>Each\u00a0effervescent tablet\u00a0contains 388 mg of\u00a0sodium.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p><em>Panocod tablets<\/em>\u00a0are available in pressure packs of 20, 50, and 100 tablets, single-dose packs of 2&#215;49 tablets, and glass jars of 2&#215;150 tablets.<\/p>\n\n\n\n<p>The tablets are white, oblong, and marked with 72M, dimensions 17.2&#215;7.3 mm.<\/p>\n\n\n\n<p><em>Panocod effervescent\u00a0tablets\u00a0are<\/em>\u00a0available in strip packs of 20, 48, 60, and 100 tablets.<\/p>\n\n\n\n<p>The effervescent&nbsp;tablets are white, scored on one side, dimensions 20&#215;5.5 mm.<\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p>Sanofi AB<\/p>\n\n\n\n<p>Box 30052<\/p>\n\n\n\n<p>104 25 Stockholm<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Panocod contains paracetamol and codeine . Paracetamol has a pain-relieving and antipyretic effect.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,18527],"tags":[20808,20785,20804,20807,20809,2363,2366,5315,20805,5314,20806,10731],"class_list":["post-20335","post","type-post","status-publish","format-standard","hentry","category-medicines","category-p","tag-benefits-of-panocod","tag-benefits-of-paracetamol","tag-panocod","tag-panocod-side-effects","tag-panocod-tablet","tag-paracetamol","tag-paracetamol-side-effects","tag-paracetamol-tablet","tag-what-is-panocod","tag-what-is-paracetamol","tag-what-panocod-is-used-for","tag-what-paracetamol-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/20335","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=20335"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/20335\/revisions"}],"predecessor-version":[{"id":20386,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/20335\/revisions\/20386"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=20335"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=20335"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=20335"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}