{"id":20332,"date":"2022-03-30T14:25:29","date_gmt":"2022-03-30T14:25:29","guid":{"rendered":"https:\/\/zeepedia.com\/?p=20332"},"modified":"2022-04-01T10:44:41","modified_gmt":"2022-04-01T10:44:41","slug":"pandemic-influenza-vaccine-h5n1-astrazeneca","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/pandemic-influenza-vaccine-h5n1-astrazeneca\/","title":{"rendered":"Pandemic influenza vaccine H5N1 A`straZeneca | Pandemic influenza vaccine (H5N1) (live attenuated, nasal) | uses, dose and side effects"},"content":{"rendered":"\n<p>nasal spray,&nbsp;suspension<br>Pandemic&nbsp;influenza vaccine&nbsp;(H5N1) (live attenuated, nasal)<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Pandemic influenza vaccine H5N1 AstraZeneca is and what it is used for<\/h2>\n\n\n\n<p>Pandemic influenza vaccine H5N1 AstraZeneca is a vaccine to prevent&nbsp;influenza&nbsp;in the event of an officially declared pandemic.&nbsp;It is used on children and adolescents from 12 months up to 18 years.<\/p>\n\n\n\n<p>Pandemic\u00a0influenza\u00a0is a type of\u00a0flu\u00a0that occurs from time to time, breaks can be less than 10 years or last for several decades.\u00a0It is spreading rapidly throughout the world.\u00a0The signs of pandemic\u00a0flu\u00a0are about the same as regular\u00a0flu but can be more severe.<\/p>\n\n\n\n<p><strong>How Pandemic influenza vaccine H5N1 AstraZeneca works<\/strong><\/p>\n\n\n\n<p>Pandemic influenza vaccine H5N1 AstraZeneca is similar to Fluenz Tetra (a nasal influenza vaccine containing four strains), except that Pandemic influenza vaccine H5N1 AstraZeneca protects against a single influenza strain in the event of an officially declared pandemic.<\/p>\n\n\n\n<p>When a person is given the vaccine, the immune system (the body&#8217;s natural defense system) produces its protection against the flu virus.\u00a0None of the ingredients in the vaccine can cause\u00a0the flu.<\/p>\n\n\n\n<p>The virus&nbsp;in the Pandemic influenza vaccine H5N1 AstraZeneca is grown in chicken eggs.&nbsp;The influenza strain used for the vaccine in the event of an officially declared pandemic is recommended by the World Health Organization.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before you receive the Pandemic influenza vaccine H5N1 AstraZeneca<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">You should not take the Pandemic flu vaccine H5N1 AstraZeneca<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>if you have previously had a severe\u00a0allergic reaction\u00a0(ie life-threatening)<\/strong>\u00a0to eggs, egg proteins, gentamicin, gelatin, or any of the other ingredients of this vaccine (listed in section 6 &#8220;Package contents and other information&#8221;).\u00a0See section 4 \u201cPossible side effects\u201d for signs of allergic reactions.\u00a0However, in a situation of a pandemic, your doctor may recommend that you be given the vaccine provided that appropriate medical treatment can be given immediately if you have an\u00a0allergic reaction.<\/li><\/ul>\n\n\n\n<p>If any of these apply to you,\u00a0<strong>tell your doctor, nurse, or pharmacist<\/strong>.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p><strong>Talk to a doctor, nurse, or pharmacist before vaccination<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if the\u00a0<strong>child is younger than\u00a0<\/strong>\u00a0<strong>12 months<\/strong>.\u00a0Children younger than 12 months should not receive this vaccine due to the risk of\u00a0side effects.<\/li><li>if you have had\u00a0an\u00a0allergic reaction\u00a0other than an\u00a0acute, life-threatening\u00a0allergic reaction\u00a0to eggs, egg proteins, gentamicin or gelatin, or any of the other ingredients of this vaccine (see section 6 &#8220;Package contents and other information&#8221;).<\/li><li>you\u00a0are already taking\u00a0<a href=\"https:\/\/zeepedia.com\/medical\/medicines\/tiplo-citrus\/\">acetylsalicylic acid<\/a>\u00a0(a substance found in many painkillers and antipyretics).\u00a0This is because there is a risk of a very rare but serious disease\u00a0(Reyes syndrome).<\/li><li>if you have a\u00a0blood disease\u00a0or\u00a0cancer\u00a0that\u00a0affects the immune system.<\/li><li>if\u00a0<strong>your doctor has told<\/strong>\u00a0you that you have\u00a0<strong>a weakened immune system<\/strong>\u00a0due to an illness, drug, or other treatment.<\/li><li>if you have\u00a0severe\u00a0asthma\u00a0or currently have to wheeze.<\/li><li>if you are\u00a0<strong>in close contact with someone who has a severely weakened immune system<\/strong>\u00a0(for example, a patient who has had a bone marrow transplant and needs isolation).<\/li><\/ul>\n\n\n\n<p>If any of these apply,\u00a0<strong>tell your doctor, nurse,<\/strong> or pharmacist before getting vaccinated.\u00a0He or she will determine if the Pandemic influenza vaccine H5N1 AstraZeneca is right for you.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines, other vaccines, and Pandemic influenza vaccine H5N1 AstraZeneca<\/h2>\n\n\n\n<p>Tell your doctor, nurse, or pharmacist if the person to be vaccinated is taking, has recently taken, or might be taking other medicines, including over-the-counter medicines.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Do not give\u00a0acetylsalicylic acid\u00a0<\/strong>(a substance found in many painkillers and antipyretics)\u00a0<strong>to children<\/strong>\u00a0for four weeks after vaccination with Pandemic influenza vaccine H5N1 AstraZeneca unless your doctor, nurse, or pharmacist tells you otherwise.\u00a0This is due to the risk of Reye&#8217;s syndrome, a very rare but serious disease that can affect the brain and liver.<\/li><li>We recommend that Pandemic influenza vaccine H5N1 AstraZeneca not be given\u00a0at the same time as influenza-specific antiviral drugs\u00a0such as\u00a0oseltamivir\u00a0and\u00a0zanamivir.\u00a0This is because the effect of the vaccine may be reduced.<\/li><\/ul>\n\n\n\n<p>Your doctor, nurse, or pharmacist will decide if the Pandemic influenza vaccine H5N1 AstraZeneca can be given at the same time as other vaccines.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>If you are\u00a0<strong>pregnant<\/strong>, think you may be pregnant, or are planning to have a baby soon,\u00a0tell your doctor, nurse, or pharmacist before getting vaccinated.\u00a0He or she will determine if the Pandemic influenza vaccine H5N1 AstraZeneca is right for you.\u00a0<\/li><li>Pandemic influenza vaccine H5N1 AstraZeneca\u00a0is not recommended\u00a0for\u00a0breastfeeding women.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Pandemic influenza vaccine H5N1 AstraZeneca has no or negligible effect on the ability to drive and use machines.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">How To Get Pandemic Influenza Vaccine H5N1 AstraZeneca<\/h2>\n\n\n\n<p><strong>Pandemic influenza vaccine H5N1 AstraZeneca is given under the supervision of a doctor, nurse, or pharmacist.<\/strong><\/p>\n\n\n\n<p>Pandemic influenza vaccine H5N1 AstraZeneca should only be used as a nasal spray.<\/p>\n\n\n\n<p><strong>Pandemic influenza vaccine H5N1 AstraZeneca must not be injected.<\/strong><\/p>\n\n\n\n<p>Pandemic influenza vaccine H5N1 AstraZeneca is given as a spray in each nostril.&nbsp;You can breathe normally while receiving the Pandemic influenza vaccine H5N1 AstraZeneca.&nbsp;You do not need to inhale or sniff.<\/p>\n\n\n\n<p><strong>Dose<\/strong><\/p>\n\n\n\n<p><strong>The recommended&nbsp;dose&nbsp;<\/strong>for children and adolescents is 0.2 ml Pandemic influenza vaccine H5N1 AstraZeneca, administered as 0.1 ml in each nostril.&nbsp;<strong>All children<\/strong>&nbsp;receive a second&nbsp;dose&nbsp;as a follow-up after a break of at least four weeks.<\/p>\n\n\n\n<p>If you have any further questions on the use of this vaccine, ask your doctor, nurse, or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.\u00a0In\u00a0clinical trials\u00a0with the vaccine, most\u00a0side effects\u00a0were mild and resolved rapidly.<\/p>\n\n\n\n<p>If you have any further\u00a0questions on the use of Pandemic influenza vaccine H5N1 AstraZeneca, ask your doctor, nurse, or pharmacist.<\/p>\n\n\n\n<p><strong>Some&nbsp;side effects&nbsp;can be serious:<\/strong><\/p>\n\n\n\n<p><strong>Very rare<\/strong><\/p>\n\n\n\n<p><em>(may affect up to 1 in 10,000 people):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Severe allergic reaction: Signs of a severe&nbsp;allergic reaction&nbsp;may include shortness of breath and swelling of the face or tongue.<\/li><\/ul>\n\n\n\n<p><strong>Tell your doctor immediately or seek\u00a0emergency\u00a0medical attention<\/strong>\u00a0if you get any of the above\u00a0side effects.<\/p>\n\n\n\n<p>In\u00a0clinical trials\u00a0in adults receiving Pandemic influenza vaccine H5N1 AstraZeneca, the most common\u00a0adverse reactions\u00a0were headache and upper respiratory tract infection (\u00a0inflammation\u00a0of the nose, throat, and sinuses).<\/p>\n\n\n\n<p><strong>Other possible&nbsp;side effects&nbsp;of Pandemic influenza vaccine H5N1&nbsp;<\/strong><strong>AstraZeneca in children and adolescents&nbsp;<\/strong><strong>:<\/strong><\/p>\n\n\n\n<p><strong>Very common<\/strong><\/p>\n\n\n\n<p><em>(may affect more than 1 in 10 people):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>runny nose or stuffy nose<\/li><li>reduced appetite<\/li><li>weakness<\/li><\/ul>\n\n\n\n<p><strong>Usual<\/strong><\/p>\n\n\n\n<p><em>(may affect up to 1 in 10 people):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>fever<\/li><li>muscle aches<\/li><li>headache<\/li><\/ul>\n\n\n\n<p><strong>Less common<\/strong><\/p>\n\n\n\n<p><em>(may affect up to 1 in 100 people):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>rash<\/li><li>nosebleeds<\/li><li>allergic reactions<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Pandemic influenza vaccine H5N1 AstraZeneca<\/h2>\n\n\n\n<p>Keep this vaccine out of the reach and sight of children.<\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the nasal pipette label after EXP.<\/p>\n\n\n\n<p>Store in a refrigerator (2\u20118 \u00b0 C).&nbsp;Do not freeze.<\/p>\n\n\n\n<p>Store the nasal pipette in the outer carton to protect it from light.<\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the pack and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<p>The active substance is:<\/p>\n\n\n\n<p>Reassortant influenza virus * (live attenuated) of the following strain **:<\/p>\n\n\n\n<p>Strain A \/ Vietnam \/ 1203\/2004 (H5N1)<\/p>\n\n\n\n<p>(A \/ Vietnam \/ 1203\/2004, MEDI 0141000136) 10&nbsp;<sup>7.0 \u00b1 0.5<\/sup>&nbsp;FFU ***<\/p>\n\n\n\n<p>&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;.. &#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;.. &#8230; per 0.2 ml&nbsp;dose<\/p>\n\n\n\n<p>* propagated in fertilized chicken eggs from healthy chicken herds.<\/p>\n\n\n\n<p>** produced in VERO cells by reverse gene technology.&nbsp;This product contains a genetically modified&nbsp;organism&nbsp;(GMO).<\/p>\n\n\n\n<p>*** fluorescent focus units<\/p>\n\n\n\n<p>This vaccine complies with the World Health Organization&#8217;s recommendation and the EU decision on the pandemic.<\/p>\n\n\n\n<p>The other ingredients are sucrose, dipotassium phosphate, potassium dihydrogen phosphate, gelatin (from pig, type A), arginine hydrochloride, monosodium glutamate monohydrate, and water for\u00a0injections.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>This vaccine is supplied as a nasal spray,&nbsp;suspension&nbsp;in a disposable nasal pipette (0.2 ml) in a pack size of 10 pcs.<\/p>\n\n\n\n<p>Suspension&nbsp;one is colorless to yellowish, clear to slightly cloudy.&nbsp;Small, white particles may be present.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p>Manufacturer:<\/p>\n\n\n\n<p>MedImmune Pharma BV,<\/p>\n\n\n\n<p>Lagelandseweg 78<\/p>\n\n\n\n<p>Nijmegen, 6545CG<\/p>\n\n\n\n<p>Netherlands<\/p>\n\n\n\n<p>MedImmune, UK Limited,<\/p>\n\n\n\n<p>Plot 6, Renaissance Way,<\/p>\n\n\n\n<p>Boulevard Industry Park,<\/p>\n\n\n\n<p>Speke,<\/p>\n\n\n\n<p>Liverpool L24 9JW,<\/p>\n\n\n\n<p>UK<\/p>\n\n\n\n<p>Contact the representative of the marketing authorization holder to find out more about this medicine:<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td><strong>Belgium \/ Belgique \/ Belgien<\/strong>AstraZeneca SA \/ NVTel: +32 2 370 48 11<\/td><td><strong>Lithuania<\/strong>UAB, AstraZeneca LietuvaTel: +370 5 2660550<\/td><\/tr><tr><td><strong>Bulgaria<\/strong>Australia Bulgaria \u0415\u041e\u041e\u0414Tel: +359 24455000<\/td><td><strong>Luxembourg \/ Luxemburg<\/strong>AstraZeneca SA \/ NVTel: +32 2 370 48 11<\/td><\/tr><tr><td><strong>Czech Republic<\/strong>AstraZeneca Czech Republic sroTel: +420 222 807 111<\/td><td><strong>Hungary<\/strong>AstraZeneca Kft.Tel .: +36 1 883 6500<\/td><\/tr><tr><td><strong>Denmark<\/strong>AstraZeneca A \/ STel: +45 43 66 64 62<\/td><td><strong>Malta<\/strong>Associated Drug Co.&nbsp;Ltd.Tel: +356 2277 8000<\/td><\/tr><tr><td><strong>Germany<\/strong>AstraZeneca GmbHTel: +49 41 03 7080<\/td><td><strong>The Netherlands<\/strong>AstraZeneca BVTel: +31 79 363 2222<\/td><\/tr><tr><td><strong>Eesti<\/strong>AstraZenecaTel: +372 6549 600<\/td><td><strong>Norway<\/strong>AstraZeneca ASTel: +47 21 00 64 00<\/td><\/tr><tr><td><strong>Greece<\/strong>AstraZeneca AE:\u0397\u03bb: +30 2\u201110 6871500<\/td><td><strong>Austria<\/strong>AstraZeneca \u00d6sterreich GmbHTel: +43 1 711 31 0<\/td><\/tr><tr><td><strong>Spain<\/strong>AstraZeneca Pharmac\u00e9utica Spain, SATel: +34 91 301 91 00<\/td><td><strong>Poland<\/strong>AstraZeneca Pharma Poland Sp.&nbsp;z ooTel .: +48 22 4 245 5 73 00<\/td><\/tr><tr><td><strong>France<\/strong>AstraZenecaTel: +33 1 41 29 40 00<\/td><td><strong>Portugal<\/strong>AstraZeneca Pharmaceutical Products, Lda.Tel: +351 21 434 61 00<\/td><\/tr><tr><td><strong>Croatia<\/strong>AstraZeneca dooTel: +385 1 4628 000<\/td><td><strong>Romania<\/strong>AstraZeneca Pharma SRLTel: +40 21 317 60 41<\/td><\/tr><tr><td><strong>Ireland<\/strong>AstraZeneca Pharmaceuticals (Ireland) LtdTel: +353 1609 7100<\/td><td><strong>Slovenia<\/strong>AstraZeneca UK LimitedTel: +386 1 51 35 600<\/td><\/tr><tr><td><strong>Iceland<\/strong>Vistor hf.Phone: +354 535 7000<\/td><td><strong>Slovak Republic<\/strong>AstraZeneca AB, ozTel: +421 2 5737 7777<\/td><\/tr><tr><td><strong>Italy<\/strong>AstraZeneca SpATel: +39 02 98011<\/td><td><strong>Finland \/ Finland<\/strong>AstraZeneca OyPuh \/ Tel: +358 10 23 010<\/td><\/tr><tr><td><strong>.\u03a0\u03c1\u03bf\u03c2<\/strong>Alexander the Great:\u0397\u03bb: +357 22490305<\/td><td><strong>Sweden<\/strong>AstraZeneca ABTel: +46 8 553 26 000<\/td><\/tr><tr><td><strong>Latvia<\/strong>SIA AstraZeneca LatvijaTel: +371 67377100<\/td><td><strong>United Kingdom<\/strong>AstraZeneca UK LtdTel: +44 1582 836 836<\/td><\/tr><\/tbody><\/table><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>Pandemic influenza vaccine H5N1 AstraZeneca is a vaccine to prevent influenza in the event of an officially declared pandemic. It is used on children and adolescents from 12 months up to 18 years.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,18527],"tags":[20825,20820,20826,20821,20816,20819,20824,20822,20817,20818,20823],"class_list":["post-20332","post","type-post","status-publish","format-standard","hentry","category-medicines","category-p","tag-benefits-of-pandemic-influenza-vaccine","tag-benefits-of-pandemic-influenza-vaccine-h5n1-astrazeneca","tag-h5n1","tag-pandemic-influenza-vaccine","tag-pandemic-influenza-vaccine-h5n1-astrazeneca","tag-pandemic-influenza-vaccine-h5n1-astrazeneca-side-effects","tag-pandemic-influenza-vaccine-side-effects","tag-what-is-pandemic-influenza-vaccine","tag-what-is-pandemic-influenza-vaccine-h5n1-astrazeneca","tag-what-pandemic-influenza-vaccine-h5n1-astrazeneca-is-used-for","tag-what-pandemic-influenza-vaccine-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/20332","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=20332"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/20332\/revisions"}],"predecessor-version":[{"id":20389,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/20332\/revisions\/20389"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=20332"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=20332"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=20332"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}