{"id":20282,"date":"2022-03-29T11:52:01","date_gmt":"2022-03-29T11:52:01","guid":{"rendered":"https:\/\/zeepedia.com\/?p=20282"},"modified":"2022-03-30T14:16:38","modified_gmt":"2022-03-30T14:16:38","slug":"palonosetron-stada","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/palonosetron-stada\/","title":{"rendered":"Palonosetron STADA &#8211; Palonosetron uses, dose and side effects"},"content":{"rendered":"\n<p>250 micrograms&nbsp;solution&nbsp;for injection<br>palonosetron<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Palonosetron STADA is and what it is used for<\/h2>\n\n\n\n<p>Palonosetron Stada belongs to a group of medicines called\u00a0serotonin\u00a0(\u00a05HT\u00a0<sub>3<\/sub>\u00a0)\u00a0antagonists.<\/p>\n\n\n\n<p>They can block the action of the substance serotonin which can cause nausea and vomiting.<\/p>\n\n\n\n<p>Palonosetron Stada is used to prevent nausea and vomiting in adults, adolescents, and children over one month of age in connection with\u00a0chemotherapy\u00a0for cancer.<\/p>\n\n\n\n<p>Palonosetron contained in Palonosetron Stada may also be approved for the treatment of other conditions not mentioned in this product information.\u00a0Ask your doctor, pharmacist, or another healthcare professional if you have any further questions, and always follow their instructions.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before you use Palonosetron STADA<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Palonosetron STADA<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to palonosetron or any of the other ingredients of this medicine (listed in section 6).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before using Palonosetron Stada.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>If you have\u00a0an acute\u00a0intestinal obstruction or have previously had constipation repeatedly.<\/li><li>If you are taking Palonosetron Stada with other medicines that may cause abnormal heart rhythm such as\u00a0amiodarone, nicardipine,\u00a0quinidine, moxifloxacin, erythromycin,\u00a0haloperidol, chlorpromazine, quetiapine, thioridazine, domperidone.<\/li><li>If you or someone in your family has or has had changes in your heart rhythm (extended\u00a0QT interval\u00a0).<\/li><li>If you have other heart problems.<\/li><li>If you have an imbalance in certain minerals in the blood, e.g.\u00a0potassium\u00a0and\u00a0magnesium, which have not been treated.<\/li><\/ul>\n\n\n\n<p>Use of Palonosetron Stada in the next few days after&nbsp;chemotherapy&nbsp;is only recommended if a new chemotherapy cycle is to be started.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Palonosetron STADA<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines, including:<\/p>\n\n\n\n<p>SSRIs\u00a0(selective serotonin reuptake inhibitors) including\u00a0fluoxetine,\u00a0paroxetine,\u00a0sertraline, fluvoxamine,\u00a0citalopram,\u00a0and escitalopram are used to treat depression and\/or anxiety.<\/p>\n\n\n\n<p>SNRIs\u00a0(\u00a0serotonin\u00a0and norepinephrine reuptake inhibitors) including\u00a0venlafaxine\u00a0and duloxetine are used to treat depression and\/or anxiety.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, breastfeeding, and fertility<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<\/p>\n\n\n\n<p><em>Pregnancy<\/em><\/p>\n\n\n\n<p>If you are pregnant or think you may be, your doctor will prescribe treatment with Palonosetron Stada only when necessary.<\/p>\n\n\n\n<p>It is not known if Palonosetron Stada can cause harmful effects when used during pregnancy.<\/p>\n\n\n\n<p><em>Breast-feeding<\/em><\/p>\n\n\n\n<p>It is not known if Palonosetron Stada passes into breast milk.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Palonosetron Stada may cause dizziness or tiredness.&nbsp;If this happens, do not drive or use any tools or machines.<\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects.\u00a0Descriptions of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Palonosetron STADA contains sodium<\/h2>\n\n\n\n<p>This medicine contains 4.65 mg\u00a0sodium\u00a0(less than 1 mmol\u00a0sodium\u00a0(23 mg)) per\u00a0vial, ie is essential &#8216;sodium-free&#8217;, but if the maximum\u00a0dose\u00a0for children (6 bottles) is administered, the sodium content is 1.2 mmol.\u00a0sodium\u00a0(28 mg).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to use Palonosetron STADA<\/h2>\n\n\n\n<p>As a rule, it is a doctor or nurse who gives an&nbsp;injection&nbsp;of Palonosetron Stada about 30 minutes before the start of chemotherapy.<\/p>\n\n\n\n<p><strong>Adults<\/strong><\/p>\n\n\n\n<p>The recommended&nbsp;dose&nbsp;of Palonosetron Stada is 250 micrograms, given as a rapid&nbsp;injection&nbsp;into a vein.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Use for children and adolescents<\/h2>\n\n\n\n<p><strong>Use in children and adolescents (aged 1 month to 17 years)<\/strong><\/p>\n\n\n\n<p>Your doctor will decide on a&nbsp;dose&nbsp;depending on your body weight, but the highest&nbsp;dose&nbsp;is 1,500 micrograms.<\/p>\n\n\n\n<p>Palonosetron Stada will be given as a slow&nbsp;infusion&nbsp;into a vein.<\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p><strong>Common<\/strong>&nbsp;(may affect up to 1 in 10 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>headache<\/li><li>dizziness<\/li><li>constipation<\/li><li>diarrhea.<\/li><\/ul>\n\n\n\n<p><strong>Uncommon<\/strong>&nbsp;(may affect up to 1 in 100 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>high or low\u00a0blood pressure<\/li><li>abnormal heart rate or insufficient blood supply to the heart<\/li><li>color changes and\/or enlargement of the veins<\/li><li>abnormally high or low amount of\u00a0potassium\u00a0in the blood<\/li><li>high blood sugar or sugar in the urine<\/li><li>low calcium in the blood<\/li><li>high levels of the pigment\u00a0bilirubin\u00a0in the blood<\/li><li>high levels of certain liver enzymes<\/li><li>elation or anxiety<\/li><li>drowsiness or insomnia<\/li><li>loss of appetite or loss of appetite<\/li><li>weakness, fatigue, fever, or\u00a0flu-like symptoms<\/li><li>numbness, burning, tingling, or ant crawling on the skin<\/li><li>skin rash with\u00a0itching<\/li><li>impaired vision or eye irritation<\/li><li>motion sickness<\/li><li>tinnitus<\/li><li>hiccups, gas,\u00a0dry mouth,\u00a0or indigestion<\/li><li>abdominal pain<\/li><li>urination difficulties<\/li><li>joint pain<\/li><li>ECG\u00a0abnormalities (prolonged\u00a0QT interval\u00a0).<\/li><\/ul>\n\n\n\n<p><strong>Very rare<\/strong>&nbsp;(may affect up to 1 in 10,000 people):<\/p>\n\n\n\n<p>allergic reactions to Palonosetron Stada.<\/p>\n\n\n\n<p>Signs may include swelling of the lips, face, tongue, or throat, difficulty breathing, collapse, rash (\u00a0hives\u00a0) with bumps and\u00a0itching, burning, or pain at the injection site.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Additional side effects in children and adolescents<\/h2>\n\n\n\n<p><strong>Common<\/strong>&nbsp;(may affect up to 1 in 10 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>headache.<\/li><\/ul>\n\n\n\n<p><strong>Uncommon<\/strong>&nbsp;(may affect up to 1 in 100 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>dizziness<\/li><li>jerky body movements<\/li><li>abnormal heart rate<\/li><li>cough or shortness of breath<\/li><li>nosebleeds<\/li><li>itchy rash or hives<\/li><li>fever<\/li><li>pain at the infusion site.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Palonosetron STADA<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the vial and carton after EXP.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>No special storage instructions.<\/p>\n\n\n\n<p>Do not use Palonosetron Stada if you notice discoloration, turbidity, or particles, it should be a clear, colorless solution.<\/p>\n\n\n\n<p>For single use only, any remaining solution should be discarded.<\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the pack and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<p>The active substance is palonosetron (as hydrochloride).<\/p>\n\n\n\n<p>Each ml of solution contains 50 micrograms of palonosetron.\u00a0One\u00a0vial\u00a0of 5 ml solution contains 250 micrograms of palonosetron.<\/p>\n\n\n\n<p>The other ingredients are mannitol (E421), disodium edetate, sodium citrate (E331), citric acid monohydrate (E330), water for injections, sodium hydroxide, and\u00a0hydrochloric acid\u00a0(E507).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>Palonosetron Stada\u00a0solution for injection\u00a0is a clear, colorless solution, free from visible particles with a\u00a0pH value\u00a0of 4.5-5.5, and is delivered in a package with a\u00a0type I glass vial with a gray rubber stopper and aluminum cap,\u00a0which\u00a0contains 5 ml of solution which is a\u00a0dose.<\/p>\n\n\n\n<p>Available in packs of 1&nbsp;vial&nbsp;containing 5 ml solution.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p>STADA Arzneimittel AG<\/p>\n\n\n\n<p>Stadastrasse 2-18<\/p>\n\n\n\n<p>61118 Bad Vilbel<\/p>\n\n\n\n<p>Germany<\/p>\n\n\n\n<p><strong>Other manufacturers<\/strong><\/p>\n\n\n\n<p>Haupt Pharma Wolfratshausen GmbH<\/p>\n\n\n\n<p>Pfaffenrieder Strasse 5, 82515 Wolfratshausen<\/p>\n\n\n\n<p>Germany<\/p>\n\n\n\n<p><strong>Local representative<\/strong><\/p>\n\n\n\n<p>STADA Nordic ApS<\/p>\n\n\n\n<p>Marielundvej 46A<\/p>\n\n\n\n<p>2730 Herlev<\/p>\n\n\n\n<p>Denmark<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Palonosetron Stada belongs to a group of medicines called serotonin ( 5HT 3 ) antagonists .<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,18527],"tags":[20686,20691,10844,20685,20687,20690,10845,20688,10846,20689],"class_list":["post-20282","post","type-post","status-publish","format-standard","hentry","category-medicines","category-p","tag-benefits-of-palonosetron","tag-benefits-of-palonosetron-stada","tag-palonosetron","tag-palonosetron-side-effects","tag-palonosetron-stada","tag-palonosetron-stada-side-effects","tag-what-is-palonosetron","tag-what-is-palonosetron-stada","tag-what-palonosetron-is-used-for","tag-what-palonosetron-stada-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/20282","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=20282"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/20282\/revisions"}],"predecessor-version":[{"id":20318,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/20282\/revisions\/20318"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=20282"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=20282"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=20282"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}