{"id":20280,"date":"2022-03-29T11:51:07","date_gmt":"2022-03-29T11:51:07","guid":{"rendered":"https:\/\/zeepedia.com\/?p=20280"},"modified":"2022-03-30T14:16:42","modified_gmt":"2022-03-30T14:16:42","slug":"palonosetron-reig-jofre","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/palonosetron-reig-jofre\/","title":{"rendered":"Palonosetron Reig Jofre &#8211; Palonosetron uses, dose and side effects"},"content":{"rendered":"\n<p>250 micrograms&nbsp;solution&nbsp;for injection<br>palonosetron<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Palonosetron Reig Jofre is and what it is used for<\/h2>\n\n\n\n<p>Palonosetron Reig Jofre belongs to a group of medicines called\u00a0serotonin\u00a0(5HT3)\u00a0antagonists.<\/p>\n\n\n\n<p>They can block the action of the chemical serotonin which can cause nausea and vomiting.<\/p>\n\n\n\n<p>Palonosetron Reig Jofre is used to prevent nausea and vomiting in adults, adolescents, and children over one month of age in connection with\u00a0chemotherapy\u00a0for cancer.<\/p>\n\n\n\n<p>Palonosetron contained in Palonosetron Reig Jofre may also be approved for the treatment of other conditions not mentioned in this product information.\u00a0Ask your doctor, pharmacist, or other healthcare professionals if you have any further questions, and always follow their instructions.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before you use Palonosetron Reig Jofre<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Palonosetron Reig Jofre<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to palonosetron or any of the other ingredients of this medicine (listed in section 6).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before using Palonosetron Reig Jofre<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you have\u00a0an acute\u00a0intestinal obstruction or have previously had constipation repeatedly,<\/li><li>if you are taking Palonosetron Reig Jofre with other medicines that can trigger abnormal heart rhythms such as\u00a0amiodarone, nicardipine,\u00a0quinidine, moxifloxacin, erythromycin,\u00a0haloperidol, chlorpromazine, quetiapine, thioridazine, domperidone,<\/li><li>if you or someone in your family has or has had changes in your heart rhythm (extended\u00a0QT interval\u00a0),<\/li><li>if you have other heart problems,<\/li><li>if you have an imbalance in certain minerals in the blood, e.g.\u00a0potassium\u00a0and\u00a0magnesium, which have not been treated.<\/li><\/ul>\n\n\n\n<p>Use of Palonosetron Reig Jofre in the next few days after&nbsp;chemotherapy&nbsp;is only recommended if a new chemotherapy cycle is to be started.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Palonosetron Reig Jofre<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines, including\u00a0SSRIs\u00a0(selective serotonin reuptake inhibitors) including\u00a0fluoxetine,\u00a0paroxetine\u00a0,\u00a0sertraline, fluvoxamine,\u00a0citalopram,\u00a0and escitalopram used to treat depression and\/or anxiety.<\/p>\n\n\n\n<p>SNRIs\u00a0(\u00a0serotonin\u00a0and norepinephrine reuptake inhibitors) including\u00a0venlafaxine\u00a0and duloxetine are used to treat depression and\/or anxiety.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, breastfeeding, and fertility<\/h2>\n\n\n\n<p><strong>Pregnancy<\/strong><\/p>\n\n\n\n<p>If you are pregnant or think you may be, your doctor will prescribe treatment with Palonosetron Reig Jofre only when necessary.<\/p>\n\n\n\n<p>It is not known if Palonosetron Reig Jofre can cause harmful effects when used during pregnancy.<\/p>\n\n\n\n<p>Ask your doctor or pharmacist for advice before taking any medicine if you are pregnant or think you may be.<\/p>\n\n\n\n<p><strong>Breast-feeding<\/strong><\/p>\n\n\n\n<p>It is not known if Palonosetron Reig Jofre passes into breast milk.<\/p>\n\n\n\n<p>If you are breastfeeding, ask your doctor or pharmacist for advice before using Palonosetron Reig Jofre.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Palonosetron Reig Jofre may cause dizziness or tiredness.&nbsp;If this happens, do not drive or use any tools or machines.<\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects.\u00a0Descriptions of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to use Palonosetron Reig Jofre<\/h2>\n\n\n\n<p>As a rule, it is a doctor or nurse who gives an&nbsp;injection&nbsp;of Palonosetron Reig Jofre about 30 minutes before the start of chemotherapy.<\/p>\n\n\n\n<p><strong>Adults<\/strong><\/p>\n\n\n\n<p>The recommended&nbsp;dose&nbsp;of Palonosetron Reig Jofre is 250 micrograms, given as a rapid&nbsp;injection&nbsp;into a vein.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Use for children and adolescents<\/h2>\n\n\n\n<p>Your doctor will decide on a&nbsp;dose&nbsp;depending on your body weight, but the highest&nbsp;dose&nbsp;is 1,500 micrograms.<\/p>\n\n\n\n<p>Palonosetron Reig Jofre will be given as a slow&nbsp;infusion&nbsp;into a vein.<\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p>Any&nbsp;side effects&nbsp;and their frequencies are listed below:<\/p>\n\n\n\n<p><strong>Adults<\/strong><\/p>\n\n\n\n<p>Common (may affect up to 1 in 10 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>headache, dizziness, constipation, and diarrhea.<\/li><\/ul>\n\n\n\n<p>Uncommon (may affect up to 1 in 100 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>high or low\u00a0blood pressure<\/li><li>abnormal heart rate or insufficient blood supply to the heart<\/li><li>color changes and\/or enlargement of the veins<\/li><li>abnormally high or low amount of\u00a0potassium\u00a0in the blood<\/li><li>high blood sugar or sugar in the urine<\/li><li>low calcium in the blood<\/li><li>high levels of\u00a0bilirubin\u00a0in the blood<\/li><li>high levels of certain liver enzymes<\/li><li>elation or anxiety<\/li><li>drowsiness or insomnia<\/li><li>loss of appetite or loss of appetite<\/li><li>weakness, fatigue, fever, or\u00a0flu-like symptoms<\/li><li>numbness, burning, tingling, or ant crawling on the skin<\/li><li>skin rash with\u00a0itching<\/li><li>impaired vision or eye irritation<\/li><li>motion sickness<\/li><li>tinnitus<\/li><li>hiccups, gas,\u00a0dry mouth,\u00a0or indigestion<\/li><li>abdominal pain<\/li><li>urination difficulties<\/li><li>joint pain<\/li><li>ECG\u00a0abnormalities (prolonged\u00a0QT interval\u00a0).<\/li><\/ul>\n\n\n\n<p>Very rare (may affect up to 1 in 10,000 people):<\/p>\n\n\n\n<p>allergic reactions to Palonosetron Reig Jofre:<\/p>\n\n\n\n<p>swelling of the lips, face, tongue, or throat, difficulty breathing, collapse, rash (\u00a0hives\u00a0) with bumps and\u00a0itching, burning, or pain at the injection site.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Additional side effects in children and adolescents<\/h2>\n\n\n\n<p>Common (may affect up to 1 in 10 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>headache.<\/li><\/ul>\n\n\n\n<p>Uncommon (may affect up to 1 in 100 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>dizziness<\/li><li>jerky body movements<\/li><li>abnormal heart rate<\/li><li>cough or shortness of breath<\/li><li>nosebleeds<\/li><li>itchy rash or hives<\/li><li>fever<\/li><li>pain at the infusion site<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Palonosetron Reig Jofre<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the vial and carton after EXP.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>No special storage instructions.<\/p>\n\n\n\n<p>For single use only, any remaining solution should be discarded.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the pack and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is palonosetron (as hydrochloride).\u00a0One ml solution contains 50 micrograms of palonosetron.\u00a0One\u00a0vial\u00a0of 5 ml solution contains 250 micrograms of palonosetron.<\/li><li>The other ingredients are mannitol, disodium edetate (dihydrate), sodium citrate (dihydrate), citric acid monohydrate, and water for injections.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>Palonosetron Reig Jofre\u00a0solution for injection\u00a0is a clear, colorless solution and is supplied in a pack with a type I glass\u00a0vial\u00a0with silicone fluorotic stopper of chlorobutyl rubber and an aluminum cap.\u00a0The vial contains 5 ml of solution, which is a\u00a0dose.<\/p>\n\n\n\n<p>Available in packs of 1&nbsp;vial&nbsp;containing 5 ml solution.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p>Laboratory Reig Jofre SA<\/p>\n\n\n\n<p>Grand Captain, 10<\/p>\n\n\n\n<p>08970 Sant Joan Desp\u00ed (Barcelona)<\/p>\n\n\n\n<p>Spain<\/p>\n\n\n\n<p><strong>Local representative:<\/strong><\/p>\n\n\n\n<p>Bioglan AB<\/p>\n\n\n\n<p>Box 50310<\/p>\n\n\n\n<p>202 13 Malm\u00f6<\/p>\n\n\n\n<p><strong>This medicinal product is authorized under the European Economic Area under the names:<\/strong><\/p>\n\n\n\n<p>Denmark: Palonosetron Reig Jofre<\/p>\n\n\n\n<p>Finland: Palonosetron Reig Jofre 250 micrograms, injection test, limos<\/p>\n\n\n\n<p>Norway: Palonosetron Reig Jofre<\/p>\n\n\n\n<p>Spain: Palonosetron Sala 250 micrograms solution for EFG injection<\/p>\n\n\n\n<p>Sweden: Palonosetron Reig Jofre<\/p>\n\n\n\n<p>United Kingdom: Palonosetron 250 micrograms solution for&nbsp;injection<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Palonosetron Reig Jofre belongs to a group of medicines called serotonin (5HT3) antagonists .<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,18527],"tags":[20686,20696,10844,20692,20695,20685,10845,20693,10846,20694],"class_list":["post-20280","post","type-post","status-publish","format-standard","hentry","category-medicines","category-p","tag-benefits-of-palonosetron","tag-benefits-of-palonosetron-reig-jofre","tag-palonosetron","tag-palonosetron-reig-jofre","tag-palonosetron-reig-jofre-side-effects","tag-palonosetron-side-effects","tag-what-is-palonosetron","tag-what-is-palonosetron-reig-jofre","tag-what-palonosetron-is-used-for","tag-what-palonosetron-reig-jofre-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/20280","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=20280"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/20280\/revisions"}],"predecessor-version":[{"id":20319,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/20280\/revisions\/20319"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=20280"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=20280"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=20280"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}