pneumonia\u00a0is caused by inhalation of vomit or other foreign matter (symptoms may include shortness of breath, cough, and fever)<\/li><\/ul>\n\n\n\nIf you have used too much Palladon, do not under any circumstances put yourself in a situation that requires alertness, e.g. driving.<\/p>\n\n\n\n
You may need emergency hospital treatment. If you are seeking medical attention, be sure to bring this leaflet and any remaining ampoules to see your doctor.<\/p>\n\n\n\n
If you forget to use Palladon<\/h2>\n\n\n\n
Use Palladon as soon as you notice that you have forgotten to take your\u00a0dose.\u00a0Never use a double\u00a0dose.<\/p>\n\n\n\n
If you forget to use Palladon or use a lower\u00a0dose\u00a0than prescribed, you will get unsatisfactory and\/or insufficient pain relief.<\/p>\n\n\n\n
If you stop using Palladon<\/h2>\n\n\n\n
You should not suddenly stop using Palladon unless your doctor tells you to.\u00a0If you want to stop using Palladon first, talk to your doctor.\u00a0If use is stopped abruptly after long-term treatment, withdrawal symptoms such as restlessness, anxiety, anxiety, difficulty sleeping, involuntary muscle contractions, tremors, and gastrointestinal problems may occur.\u00a0Your doctor will tell you how to stop the treatment, usually by gradually reducing the\u00a0dose\u00a0so that you avoid unpleasant effects.<\/p>\n\n\n\n
If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/strong><\/p>\n\n\n\nPossible side effects<\/h2>\n\n\n\n
Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n
The drug may cause allergic reactions (hypersensitivity).\u00a0The occurrence of severe allergic reactions (anaphylactic reactions) is not known.\u00a0Tell your doctor immediately if you experience sudden wheezing, difficulty breathing, eyelid, face, lip, mouth, or throat swelling, rash, or\u00a0itching, especially those that cover the whole body.<\/p>\n\n\n\n
Breathing difficulties ( respiratory depression ) are the main danger of opioid overdose.<\/p>\n\n\n\n
Most people get constipation when they use Palladon.\u00a0You can reduce the problem by increasing the amount of fiber (fruits, vegetables, wholemeal bread,\u00a0pasta, brown rice) and fluid in your diet.\u00a0If necessary, your doctor may\u00a0prescribe\u00a0laxatives.<\/p>\n\n\n\n
You may experience nausea or vomiting while using Palladon. This usually subsides after a few days, but if it continues to be a problem, your doctor may prescribe antiemetics.<\/p>\n\n\n\n
Very common side effects (<\/strong> may affect more than 1 user in 10)<\/p>\n\n\n\n- dizziness, more sleepy than usual<\/li>
- constipation<\/li>
- nausea<\/li><\/ul>\n\n\n\n
Common side effects (<\/strong> may affect up to 1 in 10 people)<\/p>\n\n\n\n- confusion<\/li>
- dry mouth, vomiting<\/li>
- itchy skin, sweating<\/li>
- urinary incontinence<\/li>
- unusual feeling of weakness<\/li>
- lost appetite<\/li>
- anxiety, insomnia<\/li>
- headache<\/li>
- pain or discomfort in the abdomen<\/li>
- skin reactions at the injection site<\/li><\/ul>\n\n\n\n
Uncommon side effects (<\/strong> may affect up to 1 in 100 people)<\/p>\n\n\n\n- restlessness<\/li>
- extreme feelings of joy, hallucinations<\/li>
- tremors, muscle twitching, tickling of hands and feet<\/li>
- blurred vision<\/li>
- low\u00a0blood pressure<\/li>
- indigestion<\/li>
- rash<\/li>
- difficulty throwing water<\/li>
- decreased sex drive,\u00a0impotence<\/li>
- withdrawal symptoms such as restlessness, anxiety, anxiety, difficulty sleeping, overactivity, tremors, and gastrointestinal problems<\/li>
- depression, nightmares<\/li>
- shortness of breath<\/li>
- diarrhea, taste changes<\/li>
- may affect the results of blood tests designed to test if the liver is functioning properly<\/li>
- fatigue<\/li>
- general malaise<\/li>
- hand, foot, or ankle swelling<\/li><\/ul>\n\n\n\n
Rare side effects (<\/strong> may affect up to 1 in 1,000 people)<\/p>\n\n\n\n- sedation<\/li>
- low\u00a0heart rate, irregular heartbeat, fast heart rate<\/li>
- breathing problems or wheezing<\/li>
- may affect the results of blood tests designed to test the proper functioning of the pancreas<\/li>
- flushing<\/li>
- lack of energy<\/li><\/ul>\n\n\n\n
Very rare side effects (<\/strong> may affect up to 1 in 10,000 people)<\/p>\n\n\n\n- irritation and hardening of the skin at the injection site (especially after repeated subcutaneous administration ).<\/li><\/ul>\n\n\n\n
Has been reported<\/strong> (occurs in an unknown number of users)<\/p>\n\n\n\n- breathing problems during sleep ( sleep apnea )<\/li>
- drug addiction<\/li>
- unpleasant or uncomfortable mood<\/li>
- seizures, convulsions<\/li>
- uncontrolled muscle movements<\/li>
- drug tolerance<\/li>
- elevated pain sensitivity (hyperalgesia, see \u201cWarnings and Precautions\u201d in section 2)<\/li>
- condition in which the small intestine (part of the gastrointestinal tract) does not function properly (paralytic ileus)<\/li>
- pupil reduction<\/li>
- itchy rash, reddening of the skin<\/li>
- withdrawal symptoms in newborns of mothers who have used Palladon during pregnancy (see section 2 “Pregnancy and lactation”)<\/li><\/ul>\n\n\n\n
How to store Palladon<\/h2>\n\n\n\n
Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n
Do not use this medicine after the expiry date which is stated on the carton or ampoule label after EXP. The expiration date is the last day of the specified month.<\/p>\n\n\n\n
Store the ampoules in the outer carton. Sensitive to light.<\/p>\n\n\n\n
Instructions for stability after use or dilution<\/strong><\/p>\n\n\n\nThis medicinal product should be used immediately after opening the package.<\/p>\n\n\n\n
Physical and chemical in-use stability has been demonstrated for 7 days at 4 \u00b0 C, 25 \u00b0 C and 37 \u00b0 C except for dilute solutions in polycarbonate syringes which should not be stored for more than 24 hours.<\/p>\n\n\n\n
From a microbiological perspective, the prepared solution should be used immediately.\u00a0If not used immediately, in-use storage times and conditions before use, which should not normally exceed 24 hours at 2-8 \u00baC, unless opened\/diluted under controlled and confirmed aseptic conditions.<\/p>\n\n\n\n
The medicinal product must be inspected visually before use and even after dilution. Only clear particle-free solutions should be used.<\/p>\n\n\n\n
For single use only.<\/p>\n\n\n\n
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.<\/p>\n\n\n\n
Contents of the pack and other information<\/h2>\n\n\n\nContent declaration<\/h2>\n\n\n\n
Palladone 2 mg \/ ml:<\/strong><\/p>\n\n\n\n- The active substance is hydromorphone hydrochloride. Each ampoule contains 2 mg of hydromorphone hydrochloride (equivalent to 1.77 mg of hydromorphone) in 1 ml solution.<\/li><\/ul>\n\n\n\n
Palladone 10 mg \/ ml:<\/strong><\/p>\n\n\n\n- The active substance is hydromorphone hydrochloride. Each ampoule contains 10 mg of hydromorphone hydrochloride (equivalent to 8.87 mg of hydromorphone) in 1 ml solution.<\/li><\/ul>\n\n\n\n
Palladone 20 mg \/ ml:<\/strong><\/p>\n\n\n\n- The active substance is hydromorphone hydrochloride. Each ampoule contains 20 mg of hydromorphone hydrochloride (equivalent to 17.7 mg of hydromorphone) in 1 ml solution.<\/li><\/ul>\n\n\n\n
Palladone 50 mg \/ ml:<\/strong><\/p>\n\n\n\n