if fatigue or episodes of sudden drowsiness occur.<\/li><\/ul>\n\n\n\nTalk to your doctor if any of the above have affected you in the past.\u00a0Also, talk to a doctor if you experience any of the above while taking Oxycodone \/ Naloxone GL<\/p>\n\n\n\n
Oxycodone \/ Naloxone GL is not recommended for the treatment of patients with advanced cancer of the gastrointestinal tract or pelvis where intestinal obstruction may be a problem.<\/p>\n\n\n\n
If you experience severe diarrhea at the beginning of treatment (within the first 3 to 5 days), this may be due to the effect of naloxone.\u00a0It may be a sign that your bowel movements are returning to normal.\u00a0Contact a doctor if diarrhea persists after 3 to 5 days, or is worrying.<\/p>\n\n\n\n
If you have used high\u00a0doses\u00a0of another\u00a0opioid, you may initially experience withdrawal symptoms (such as restlessness, sweating, and muscle pain) when switching to Oxycodone \/ Naloxone GL. If you experience withdrawal symptoms, you may need special medical attention.<\/p>\n\n\n\n
Tell your doctor that you are taking Oxycodone \/ Naloxone GL if you need surgery.<\/p>\n\n\n\n
If you have been taking Oxycodone \/ Naloxone GL for a long time, you may become tolerant.\u00a0This means that you may need a higher\u00a0dose\u00a0to achieve the desired effect.\u00a0Prolonged use of this drug can also lead to physical dependence.\u00a0Medicines containing oxycodone should be avoided in patients with current or past alcohol, drug, or drug abuse.\u00a0Withdrawal symptoms can occur if treatment is stopped too suddenly.\u00a0If you no longer need treatment, gradually reduce your daily\u00a0dose\u00a0in consultation with your doctor.<\/p>\n\n\n\n
There is a risk of developing psychological dependence on oxycodone.<\/p>\n\n\n\n
Residues of\u00a0prolonged-release tablets\u00a0may be present in the feces.\u00a0This is nothing to worry about, as the active substances have already been released in the stomach and intestines and absorbed into the body.<\/p>\n\n\n\n
Improper use of Oxycodone \/ Naloxone GL<\/strong><\/p>\n\n\n\nOxycodone \/ Naloxone GL should never be abused, especially if you have a drug addiction.\u00a0If you are addicted to drugs such as heroin, morphine, or\u00a0methadone\u00a0, you are likely to suffer from severe withdrawal symptoms if you abuse Oxycodone \/ Naloxone GL, as it contains the active substance naloxone.\u00a0Pre-existing withdrawal symptoms may worsen.<\/p>\n\n\n\n
Oxycodone \/ Naloxone GL prolonged-release tablets should never be abused by dissolving and injecting (eg into a blood vessel) or inhaling. The tablets contain talc that can destroy local tissue ( necrosis ) and cause changes in the lung tissue (lung granuloma). Improper use can also have other serious consequences that can be life-threatening.<\/p>\n\n\n\n
The prolonged-release tablets\u00a0must be swallowed whole so as not to affect the slow\u00a0release\u00a0of oxycodone from the tablets.\u00a0The tablets must not be split, broken, chewed, or crushed.\u00a0If the tablets are split, broken, chewed, or crushed, this may cause the body to take up a potentially life-threatening\u00a0dose of\u00a0oxycodone (see section 3 \u201cIf you take more Oxycodone \/ Naloxone GL\u201d).<\/p>\n\n\n\n
Children and young people<\/h2>\n\n\n\n
This medicine should not be given to children or adolescents under 18 years of age when safety and efficacy have not been established.<\/p>\n\n\n\n
Other medicines and Oxycodone \/ Naloxone GL<\/h2>\n\n\n\n
Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.<\/p>\n\n\n\n
The risk of side effects increases if you take Oxycodone \/ Naloxone GL at the same time as medicines that affect brain function. For example, you may feel very tired and breathing difficulties (slow and shallow breathing) may worsen.<\/p>\n\n\n\n
Examples of drugs that affect brain function:<\/p>\n\n\n\n
- other strong painkillers (\u00a0opioids\u00a0)<\/li>
- hypnotics and sedatives (\u00a0sedatives,\u00a0hypnotics\u00a0)<\/li>
- antidepressant drugs (such as\u00a0paroxetine\u00a0or\u00a0fluoxetine\u00a0)<\/li>
- medicines used to treat\u00a0allergies, motion sickness, or nausea (\u00a0antihistamines\u00a0or antiemetics)<\/li>
- other drugs that affect the nervous system (phenothiazines,\u00a0neuroleptics\u00a0)<\/li><\/ul>\n\n\n\n
The risk of\u00a0side effects\u00a0is increased if you take antidepressant drugs (for example,\u00a0citalopram, duloxetine, escitalopram,\u00a0fluoxetine, fluvoxamine,\u00a0paroxetine,\u00a0sertraline\u00a0,\u00a0venlafaxine\u00a0).\u00a0These drugs can affect or be affected by oxycodone, and you may experience symptoms such as involuntary, rhythmic muscle contractions, including in the muscles that control eye movements, sudden movements, heavy sweating, tremors, excessive reflexive movements, increased muscle tension, body temperature above 38 \u00b0 C.\u00a0Contact your doctor if you experience these symptoms.<\/p>\n\n\n\n
Concomitant use of Oxycodone \/ Naloxone GL and sedatives or medicines for insomnia such as benzodiazepines or similar medicines increases the risk of drowsiness, difficulty breathing ( respiratory depression ), coma and may be life-threatening. Due to this, concomitant use should only be considered when other treatment options are not possible. If your doctor prescribes Oxycodone \/ Naloxone GL at the same time as sedatives, dose one and the treatment time should be limited by your doctor.<\/p>\n\n\n\n
Tell your doctor if you are taking any sedatives and carefully follow your doctor’s dose recommendations. It may be helpful to inform friends or relatives about paying attention to the signs and symptoms described above. Contact a doctor if you experience any of these symptoms.<\/p>\n\n\n\n
Talk to a doctor if you are taking:<\/p>\n\n\n\n
- drugs that reduce the\u00a0coagulation\u00a0capacity of the blood (coumarin derivatives), the coagulation time may be faster or slower<\/li>
- Macrolide type\u00a0antibiotics\u00a0are (eg clarithromycin, erythromycin, telithromycin\u00a0)<\/li>
- antifungal drugs of the type azoles (eg\u00a0ketoconazole\u00a0, voriconazole, itraconazole, posaconazole)<\/li>
- ritonavir or other\u00a0protease inhibitors\u00a0(used to treat\u00a0HIV, eg indinavir, nelfinavir, saquinavir)<\/li>
- cimetidine (used to treat\u00a0stomach ulcers, stomach upset, or heartburn).<\/li>
- rifampicin (used to treat\u00a0tuberculosis\u00a0)<\/li>
- carbamazepine (used to treat seizures and certain pain conditions)<\/li>
- phenytoin\u00a0(used to treat seizures)<\/li>
- St. John’s wort\u00a0(also known as Hypericum perforatum).<\/li>
- quinidine\u00a0(used to treat irregular heartbeat).<\/li><\/ul>\n\n\n\n
Oxycodone \/ Naloxone GL with food, drink, and alcohol<\/h2>\n\n\n\n
Alcohol intake during treatment with Oxycodone \/ Naloxone GL may make you more tired or increase the risk of serious\u00a0side effects\u00a0such as shallow breathing with a risk of respiratory arrest and loss of consciousness.\u00a0Alcohol intake should be avoided during treatment with Oxycodone \/ Naloxone GL<\/p>\n\n\n\n
Intake of grapefruit juice should be avoided during treatment with Oxycodone \/ Naloxone GL<\/p>\n\n\n\n
Pregnancy, breastfeeding, and fertility<\/h2>\n\n\n\n
If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<\/p>\n\n\n\n
Pregnancy<\/strong><\/p>\n\n\n\nThe use of Oxycodone \/ Naloxone GL should be avoided during pregnancy as far as possible. Prolonged use of oxycodone during pregnancy can lead to withdrawal symptoms in newborns. Treatment with oxycodone during childbirth may cause respiratory depression (slow and shallow breathing) in the newborn.<\/p>\n\n\n\n
Breast-feeding<\/strong><\/p>\n\n\n\nBreast-feeding must be discontinued during treatment with Oxycodone \/ Naloxone GL Oxycodone passes into breast milk.\u00a0It is not known whether naloxone also passes into breast milk.\u00a0Therefore, the risk to the breast-fed baby can not be ruled out, especially after taking several\u00a0doses\u00a0of Oxycodone \/ Naloxone GL<\/p>\n\n\n\n
Driving and using machines<\/h2>\n\n\n\n
This medicine may affect your ability to drive or use machines as it may make you tired or dizzy.\u00a0This is most likely at the start of treatment, after a dose increase, or after switching from another medicine.\u00a0These\u00a0side effects\u00a0should go away when you are on a steady\u00a0dose.<\/p>\n\n\n\n
This drug has been associated with drowsiness and episodes of sudden drowsiness.\u00a0If you experience these\u00a0side effects, do not drive or use machines.\u00a0Talk to your doctor if this happens.<\/p>\n\n\n\n
You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects.<\/p>\n\n\n\n
Descriptions of these effects and side effects can be found in other sections. Read all the information in this leaflet for guidance. If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n
Talk to your doctor or pharmacist if you are not sure if it is safe to drive a vehicle during treatment with this medicine.<\/p>\n\n\n\n
Oxycodone \/ Naloxone GL contains excipients<\/h2>\n\n\n\n
Oxycodone \/ Naloxone GL 5 mg \/ 2.5 mg and 10mg \/ 5mg contain lactose . If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.<\/p>\n\n\n\n
How to use Oxycodone \/ Naloxone GL<\/h2>\n\n\n\n
Always take this medicine exactly as your doctor has told you. Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n
For\u00a0doses\u00a0that are not achievable\/practical with this strength, there are other strengths of this medicine.<\/p>\n\n\n\n
Unless your doctor prescribes otherwise, the recommended dose is:<\/strong><\/p>\n\n\n\nFor the treatment of pain<\/em><\/strong><\/p>\n\n\n\nAdults<\/strong><\/p>\n\n\n\nThe usual starting dose is 10 mg oxycodone hydrochloride \/ 5 mg naloxone hydrochloride every 12 hours.<\/p>\n\n\n\n
Your doctor will decide how much to take each day and how to distribute your total daily\u00a0dose\u00a0morning and evening.\u00a0Your doctor will also decide on any necessary dose adjustments during treatment, depending on your level of pain and individual sensitivity.\u00a0You should receive the lowest\u00a0dose\u00a0required for pain relief.\u00a0If you have already been treated with\u00a0opioids, your treatment with Oxycodone \/ Naloxone GL can be started with a higher\u00a0dose.<\/p>\n\n\n\n
The highest daily\u00a0dose\u00a0is 160 mg oxycodone hydrochloride and 80 mg naloxone hydrochloride.\u00a0If you need a higher\u00a0dose, your doctor may give you additional oxycodone without naloxone.\u00a0However, the maximum daily\u00a0dose of\u00a0oxycodone hydrochloride should not exceed 400 mg.\u00a0The beneficial effect of naloxone on bowel movements may be affected if additional oxycodone is given without additional naloxone.<\/p>\n\n\n\n
If you experience pain between\u00a0doses, you may need to take additional fast-acting painkillers.\u00a0Oxycodone \/ Naloxone GL is not suitable for this.\u00a0Talk to your doctor.<\/p>\n\n\n\n
Talk to your doctor or pharmacist if you find that Oxycodone \/ Naloxone GL is too strong or too weak.<\/p>\n\n\n\n
Elderly patients <\/strong>r<\/strong><\/p>\n\n\n\nIn general, no dose adjustment is necessary for elderly patients with normal renal and\/or hepatic function.<\/p>\n\n\n\n
Hepatic or renal impairment<\/strong><\/p>\n\n\n\nIf you have kidney problems or mild liver problems, your doctor will prescribe Oxycodone \/ Naloxone GL with special caution. You should not take Oxycodone \/ Naloxone GL if you have moderate or severe liver problems (see also section 2. \u201cDo not take Oxycodone \/ Naloxone GL\u201d and \u201cWarnings and precautions\u201d).<\/p>\n\n\n\n
Method of administration<\/strong><\/p>\n\n\n\nTo be swallowed.<\/p>\n\n\n\n
Swallow the tablets whole with a glass of water.\u00a0The tablets can be taken with or without food.\u00a0Take them every 12 hours according to a fixed schedule.\u00a0For example, if you take one tablet at 8 in the morning, take the next tablet at 20 in the evening.\u00a0The prolonged-release tablets\u00a0must not be split, broken, chewed, or crushed.<\/p>\n\n\n\n
Instructions for opening the blister pack:<\/strong><\/p>\n\n\n\nThis medicine has child-resistant packaging.\u00a0The prolonged-release tablets\u00a0must be squeezed out of the blister pack with a firm hand.<\/p>\n\n\n\n
Duration of treatment<\/strong><\/p>\n\n\n\nYou should not take Oxycodone \/ Naloxone GL for longer than you need. If you have been taking Oxycodone \/ Naloxone GL for a long time, your doctor should check regularly that you still need it.<\/p>\n\n\n\n
Use for children and adolescents<\/h2>\n\n\n\n
Children and adolescents under 18 years of age: No studies have been performed to demonstrate that Oxycodone \/ Naloxone GL works properly in children and adolescents or that it is safe for them to take. It is therefore not recommended for patients under 18 years of age.<\/p>\n\n\n\n
If you use more Oxycodone \/ Naloxone GL then you should \u00a0<\/h2>\n\n\n\n
If you have ingested too much medicine or if e.g.\u00a0If a child has ingested the medicine by mistake, contact a doctor, hospital, or the Poison Information Center (tel. 112) for risk assessment and advice.<\/p>\n\n\n\n
If you take more than the prescribed\u00a0dose, you must tell your doctor immediately.<\/p>\n\n\n\n
Overdose can lead to:<\/p>\n\n\n\n
- reduced pupil in the eye<\/li>
- slower or weaker breathing than expected ( respiratory depression )<\/li>
- drowsiness or loss of consciousness<\/li>
- low muscle tension ( hypotension )<\/li>
- decreased heart rate<\/li>
- drop in blood pressure.<\/li><\/ul>\n\n\n\n
In severe cases, loss of consciousness (\u00a0coma\u00a0), fluid in the lungs, and circulatory collapse can occur, which can be life-threatening.<\/p>\n\n\n\n
Avoid situations that require attention, e.g. to drive vehicles.<\/p>\n\n\n\n
If you forget to use Oxycodone \/ Naloxone GL<\/h2>\n\n\n\n
If you forget to take Oxycodone \/ Naloxone GL or if you take a lower\u00a0dose\u00a0than the prescribed\u00a0dose, you may not experience any effect.<\/p>\n\n\n\n
If you forget to take your\u00a0dose, follow the instructions below:<\/p>\n\n\n\n
- If there are\u00a08 hours or more<\/em>\u00a0left until the next regular dose: Take the missed\u00a0dose\u00a0immediately and then continue with your usual dosing schedule.<\/li>
- If it is\u00a0less than 8 hours<\/em>\u00a0until the next regular dose: Take the missed\u00a0dose\u00a0one and then wait for 8 hours before taking the next\u00a0dose.\u00a0Try to return to your usual dosing schedule (eg at 8 in the morning and at 20 in the evening).<\/li><\/ul>\n\n\n\n
Do not take more than one\u00a0dose\u00a0within each eight hours.<\/p>\n\n\n\n
Do not take a double\u00a0dose\u00a0to make up for a forgotten\u00a0dose.<\/p>\n\n\n\n
If you stop using Oxycodone \/ Naloxone GL<\/h2>\n\n\n\n
Do not stop taking Oxycodone \/ Naloxone GL without talking to your doctor first.<\/p>\n\n\n\n
If you do not need further treatment, your doctor will tell you how to gradually reduce your daily\u00a0dose.\u00a0In this way, withdrawal symptoms such as restlessness, sweating, and muscle pain can be avoided.<\/p>\n\n\n\n
If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n
Possible side effects<\/h2>\n\n\n\n
Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n
Important side effects or signs to be aware of and what to do if you are affected:<\/strong><\/p>\n\n\n\nStop taking Oxycodone \/ Naloxone GL, consult a doctor, or see your nearest emergency department immediately if you experience any of the following symptoms:<\/p>\n\n\n\n
- Slower or shallower breathing (\u00a0respiratory depression\u00a0).\u00a0This is the most serious\u00a0side effect\u00a0of Oxycodone \/ Naloxone GL and is most common in elderly and debilitated patients.<\/li>
- Opioids\u00a0can also cause a sharp drop in blood pressure in sensitive patients.<\/li>
- Swelling of the face, tongue, or throat, difficulty swallowing,\u00a0hives, difficulty breathing, and drop in blood pressure (anaphylactic reaction).<\/li><\/ul>\n\n\n\n
The following side effects have been reported in patients treated for pain<\/em><\/strong><\/p>\n\n\n\nCommon<\/strong> (may affect up to 1 in 10 people.)<\/p>\n\n\n\n- abdominal pain, indigestion, constipation, diarrhea, gas<\/li>
- dry mouth<\/li>
- vomiting, nausea<\/li>
- decreased appetite, loss of appetite<\/li>
- feeling dizzy or “spinning”<\/li>
- headache<\/li>
- hot flashes, sweating<\/li>
- general weakness, fatigue, or exhaustion<\/li>
- itching\u00a0of the skin, skin reactions\/rash<\/li>
- difficulty sleeping, drowsiness<\/li><\/ul>\n\n\n\n
Uncommon<\/strong> (may affect up to 1 in 100 people)<\/p>\n\n\n\n- inflated stomach<\/li>
- abnormal thoughts<\/li>
- anxiety, confusion, depression, nervousness, difficulty concentrating<\/li>
- a feeling of tightness in the chest, especially if you already have coronary artery disease, chest pain<\/li>
- drop in blood pressure, high\u00a0blood pressure<\/li>
- withdrawal symptoms such as upset<\/li>
- fainting<\/li>
- palpitation<\/li>
- gallkolik<\/li>
- general malaise<\/li>
- pain<\/li>
- swollen hands, ankles, or feet<\/li>
- impaired speech<\/li>
- shaking<\/li>
- breathing difficulties<\/li>
- restlessness<\/li>
- overindulge<\/li>
- elevated liver enzymes<\/li>
- Runny nose<\/li>
- cough<\/li>
- hypersensitivity \/ allergic reactions<\/li>
- weight loss<\/li>
- injuries from accidents<\/li>
- increased need to urinate<\/li>
- muscle cramps, muscle twitching, muscle pain<\/li>
- impaired vision<\/li>
- epileptic seizures (especially in people with\u00a0epilepsy\u00a0or prone to seizures)<\/li><\/ul>\n\n\n\n
Rare<\/strong> (may affect up to 1 in 1,000 people)<\/p>\n\n\n\n- increased heart rate<\/li>
- changes in teeth<\/li>
- weight gain<\/li>
- yawning<\/li><\/ul>\n\n\n\n
Has been reported<\/strong> (occurs in an unknown number of users)<\/p>\n\n\n\n- euphoria<\/li>
- severe drowsiness<\/li>
- erectile dysfunction <\/li>
- nightmares<\/li>
- hallucinations<\/li>
- shallow breathing<\/li>
- difficulties with urination<\/li>
- tingling in hands or feet<\/li>
- belching<\/li><\/ul>\n\n\n\n
The active substance oxycodone, when not combined with naloxone, is known for the following differentiating side effects:<\/strong><\/p>\n\n\n\nBreathing problems such as slower or weaker breathing than expected (\u00a0respiratory depression\u00a0), decreased\u00a0pupils\u00a0in the eye, muscle cramps, and decreased cough reflex.<\/p>\n\n\n\n
Common<\/strong> (may affect up to 1 in 10 people.)<\/p>\n\n\n\n- mood swings and personality changes (eg depression, extreme happiness)<\/li>
- decreased activity, increased activity<\/li>
- difficulty urinating<\/li>
- hiccup<\/li><\/ul>\n\n\n\n
Uncommon<\/strong> (may affect up to 1 in 100 people)<\/p>\n\n\n\n- impaired concentration, agitation<\/li>
- migraine<\/li>
- abnormal taste<\/li>
- increased muscle tension, involuntary muscle contractions<\/li>
- drug dependence, drug tolerance<\/li>
- intestinal obstruction ( ileus )<\/li>
- dry skin, reddening of the skin<\/li>
- decreased sensitivity to pain or touch<\/li>
- abnormal coordination<\/li>
- voice changes ( dysphonia )<\/li>
- fluid retention<\/li>
- hearing problems<\/li>
- cold sores, sore gums<\/li>
- difficulty swallowing<\/li>
- perceptual disorders (eg hallucinations, feelings of unreality)<\/li>
- decreased sexual drive<\/li>
- dehydration, thirst<\/li><\/ul>\n\n\n\n
Rare<\/strong> (may affect up to 1 in 1,000 people)<\/p>\n\n\n\n- rash with itching ( hives )<\/li>
- herpes simplex (which can cause blisters around the mouth or genital areas)<\/li>
- increased appetite<\/li>
- black (tarry) feces<\/li>
- bleeding gums<\/li><\/ul>\n\n\n\n
No known frequency<\/strong> (can not be calculated from the available data)<\/p>\n\n\n\n- acute\u00a0general\u00a0allergic reaction\u00a0(anaphylactic reactions)<\/li>
- missed menstruation<\/li>
- problems with bile flow<\/li>
- Prolonged use of Oxycodone \/ Naloxone GL during pregnancy may cause life-threatening withdrawal symptoms in newborns.\u00a0Symptoms to pay attention to are irritability, hyperactivity, abnormal sleep patterns, crying, shaking, nausea, diarrhea, and no weight gain.
Reporting of\u00a0side effects\u00a0if you get\u00a0any side effects, talk to your doctor or pharmacist.\u00a0This also applies to any\u00a0side effects\u00a0not mentioned in this information.\u00a0You can also report\u00a0side effects\u00a0directly to the Medical Products Agency (see details below).\u00a0By reporting\u00a0side effects, you can help increase drug safety information.
The Medical Products AgencyBox 26751 03 Uppsalawww.lakemedelsverket.se<\/li><\/ul>\n\n\n\nHow to store Oxycodone \/ Naloxone GL<\/h2>\n\n\n\n
Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n
Do not use this medicine after the expiry date which is stated on the blister and the carton after EXP. or EXP. The expiration date is the last day of the specified month.<\/p>\n\n\n\n
Do not store above 25 \u00b0 C.<\/p>\n\n\n\n
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.<\/p>\n\n\n\n
Contents of the pack and other information<\/h2>\n\n\n\nContent declaration<\/h2>\n\n\n\n
The active substances are oxycodone hydrochloride and naloxone hydrochloride.<\/p>\n\n\n\n
- Oxycodone \/ Naloxone GL 5 mg \/ 2.5 mg:<\/em> One prolonged-release tablet contains 5 mg oxycodone hydrochloride equivalent to 4.5 mg oxycodone and 2.5 mg naloxone hydrochloride equivalent to 2.75 mg naloxone hydrochloride dihydrate equivalent to 2.25 mg naloxone.<\/li>
- Oxycodone \/ Naloxone GL 10 mg \/ 5 mg:<\/em> One prolonged-release tablet contains 10 mg oxycodone hydrochloride equivalent to 9 mg oxycodone and 5 mg naloxone hydrochloride as 5.5 mg naloxone hydrochloride dihydrate equivalent to 4.5 mg naloxone.<\/li>
- Oxycodone \/ Naloxone GL 20 mg \/ 10 mg<\/em> : One prolonged-release tablet contains 20 mg oxycodone hydrochloride equivalent to 18 mg oxycodone and 10 mg naloxone hydrochloride as 10.99 mg naloxone hydrochloride dihydrate equivalent to 9 mg naloxone.<\/li>
- Oxycodone \/ Naloxone GL 30 mg \/ 15 mg <\/em>:<\/em> One prolonged-release tablet contains 30 mg oxycodone hydrochloride equivalent to 26.9 mg oxycodone and 15 mg naloxone hydrochloride as 16.448 mg naloxone hydrochloride dihydrate equivalent to 13.5 mg naloxone.<\/li>
- Oxycodone \/ Naloxone GL 40 mg \/ 20 mg<\/em> : One prolonged-release tablet contains 40 mg oxycodone hydrochloride equivalent to 36 mg oxycodone and 20 mg naloxone hydrochloride as 21.98 mg naloxone hydrochloride dihydrate equivalent to 18 mg naloxone.<\/li><\/ul>\n\n\n\n
The other ingredients are<\/p>\n\n\n\n
Tablet core<\/em> : Poly (vinyl acetate), Povidone K 30, sodium lauryl sulfate, silica, microcrystalline cellulose, lactose monohydrate (Oxycodone \/ Naloxone GL 5 mg \/ 2.5 mg and 10 mg \/ 5 mg)<\/em> , colloidal , anhydrous silica, magnesium stearate.<\/p>\n\n\n\nFilm coating<\/em> : polyvinyl alcohol partially hydrolysed, macrogol 3350, titanium dioxide (E 171), talc, brilliant blue FCF aluminum lacquer (E 133) ( Oxycodone \/ Naloxone GL 5 mg \/ 2.5 mg),<\/em> red iron oxide (E 172) (Oxycodone \/ Naloxone GL 20 mg \/ 10 mg, Oxycodone \/ Naloxone GL 30 mg \/ 15 mg),<\/em> yellow iron oxide (E 172) (Oxycodone \/ Naloxone GL 30 mg \/ 15 mg, Drug name> 40 mg \/ 20 mg),<\/em> black iron oxide (E 172) ( Oxycodone \/ Naloxone GL 30 mg \/ 15 mg)<\/em> .<\/p>\n\n\n\nWhat the medicine looks like and the contents of the pack<\/h2>\n\n\n\n
Oxycodone \/ Naloxone GL is a\u00a0prolonged-release tablet, which means that the active substances are released for a longer period.\u00a0Their effect lasts for 12 hours.<\/p>\n\n\n\n
Oxycodone \/ Naloxone GL 5 mg \/ 2.5 mg\u00a0prolonged-release tablets\u00a0are light blue, round, and biconvex\u00a0prolonged-release tablets\u00a0with a film coating with \u201c5\u201d embossed on one side.<\/p>\n\n\n\n
Oxycodone \/ Naloxone GL 10 mg \/ 5 mg\u00a0prolonged-release tablets\u00a0are white to off-white, round, and biconvex\u00a0prolonged-release tablets\u00a0with a film coating with \u201c10\u201d debossed on one side.<\/p>\n\n\n\n
Oxycodone \/ Naloxone GL 20 mg \/ 10 mg\u00a0prolonged-release tablets\u00a0are light pink, round, and biconvex\u00a0prolonged-release tablets\u00a0with a film coating with \u201c20\u201d embossed on one side.<\/p>\n\n\n\n
Oxycodone \/ Naloxone GL 30 mg \/ 15 mg\u00a0prolonged-release tablets\u00a0are brown, round, and biconvex\u00a0prolonged-release tablets\u00a0with a film coating with \u201c30\u201d debossed on one side.<\/p>\n\n\n\n
Oxycodone \/ Naloxone GL 40 mg \/ 20 mg\u00a0prolonged-release tablets\u00a0are yellow, round, and biconvex\u00a0prolonged-release tablets\u00a0with a film coating with \u201c40\u201d debossed on one side.<\/p>\n\n\n\n
Blister packs of 7, 10, 14, 20, 28, 30, 50, 56, 60, 98 and 100 prolonged-release tablets .<\/p>\n\n\n\n
Not all pack sizes may be marketed.<\/p>\n\n\n\n
Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n
GL Pharma GmbH,<\/p>\n\n\n\n
Schlossplatz 1,<\/p>\n\n\n\n
AT-8502 Lannach,<\/p>\n\n\n\n
Austria<\/p>\n","protected":false},"excerpt":{"rendered":"
You have been prescribed Oxycodone \/ Naloxone GL for the treatment of severe pain that can only be managed with enough analgesic opioids .<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,18526],"tags":[20509,20513,20512,18364,18367,20508,20492,16081,16084,20507,20495,20501,20510,18365,20493,16082,20511,18366,16091,20494],"class_list":["post-20144","post","type-post","status-publish","format-standard","hentry","category-medicines","category-o","tag-naloxone-gl","tag-naloxone-gl-side-effects","tag-naloxone-gl-tablet","tag-naloxone-hydrochloride","tag-naloxone-hydrochloride-side-effects","tag-naloxone-hydrochloride-tablet","tag-oxycodone","tag-oxycodone-hydrochloride","tag-oxycodone-hydrochloride-side-effects","tag-oxycodone-hydrochloride-tablet","tag-oxycodone-side-effects","tag-oxycodone-tablet","tag-what-is-naloxone-gl","tag-what-is-naloxone-hydrochloride","tag-what-is-oxycodone","tag-what-is-oxycodone-hydrochloride","tag-what-naloxone-gl-is-used-for","tag-what-naloxone-hydrochloride-is-used-for","tag-what-oxycodone-hydrochloride-is-used-for","tag-what-oxycodone-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/20144","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=20144"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/20144\/revisions"}],"predecessor-version":[{"id":20180,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/20144\/revisions\/20180"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=20144"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=20144"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=20144"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}