{"id":19940,"date":"2022-03-21T11:45:39","date_gmt":"2022-03-21T11:45:39","guid":{"rendered":"https:\/\/zeepedia.com\/?p=19940"},"modified":"2022-03-22T11:32:42","modified_gmt":"2022-03-22T11:32:42","slug":"oriptan","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/oriptan\/","title":{"rendered":"Oriptan &#8211; Sumatriptan uses, dose and side effects"},"content":{"rendered":"\n<p>50 mg&nbsp;film-coated tablets<br>sumatriptan<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Oriptan is and what it is used for<\/h2>\n\n\n\n<p>Each tablet contains a single dose of sumatriptan and belongs to a group of medicines called triptans (also called 5-HT1&nbsp;receptor&nbsp;agonists&nbsp;).<\/p>\n\n\n\n<p>Oriptan is used to treat migraine attacks with or without\u00a0aura.<\/p>\n\n\n\n<p>The migraine symptoms are probably due to a temporary dilation of blood vessels in the head.&nbsp;Sumatriptan is believed to reduce the dilation of these blood vessels.&nbsp;This in turn results in relief of headaches and reduction of other migraine symptoms such as nausea or vomiting and sensitivity to light and sound.<\/p>\n\n\n\n<p>Oriptan is not intended for the treatment of other types of headaches, e.g.\u00a0tension headaches.<\/p>\n\n\n\n<p>Sumatriptan contained in Oriptan may also be approved for the treatment of other conditions not mentioned in this leaflet.\u00a0Ask your doctor, pharmacist, or other healthcare professionals if you have any further questions, and always follow their instructions.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before using Oriptan<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Oriptan<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are&nbsp;<strong>allergic<\/strong>&nbsp;to sumatriptan or any of the other ingredients of this medicine (listed in section 6).<\/li><li>-if you have&nbsp;<strong>heart problems<\/strong>&nbsp;such as arterial stenosis or chest pain (angina), or have already had a heart attack.<\/li><li>if you have&nbsp;<strong>poor blood circulation<\/strong>&nbsp;in your legs that causes cramp-like pain when you walk (&nbsp;peephole&nbsp;).<\/li><li>if you have had a&nbsp;<strong>stroke<\/strong>&nbsp;or mini-&nbsp;stroke&nbsp;(also called&nbsp;transient&nbsp;ischemic attack or&nbsp;TIA&nbsp;).<\/li><li>if you have&nbsp;<strong>high&nbsp;blood pressure<\/strong>&nbsp;.&nbsp;You may be able to take sumatriptan if your high&nbsp;blood pressure&nbsp;is mild and being treated.<\/li><li>if you have&nbsp;<strong>severe liver disease<\/strong>&nbsp;.<\/li><li>if you are taking other&nbsp;<strong>migraine medications<\/strong>&nbsp;including those containing&nbsp;ergotamine&nbsp;or similar medicines such as methysergide maleate or any triptan or 5-HT1&nbsp;receptor agonist&nbsp;(such as naratriptan or zolmitriptan)<\/li><li>you are taking any of the following&nbsp;<strong>antidepressant drugs<\/strong>&nbsp;:<ul><li><strong>MAO inhibitors<\/strong>&nbsp;(&nbsp;monoamine oxidase inhibitors&nbsp;) or if you have taken&nbsp;MAO inhibitors&nbsp;in the last two weeks.<\/li><li><strong>SSRIs&nbsp;<\/strong>(selective serotonin reuptake inhibitors) including&nbsp;citalopram&nbsp;,&nbsp;fluoxetine&nbsp;, fluvoxamine,&nbsp;paroxetine&nbsp;or&nbsp;sertraline&nbsp;.<\/li><li><strong>SNRIs<\/strong>&nbsp;(&nbsp;serotonin&nbsp;-noradrenaline reuptake inhibitors) including venlaflaxine and duloxetine.<\/li><\/ul><\/li><li>you are&nbsp;<strong>a child under 18 years of age<\/strong>&nbsp;.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Before you start taking Oriptan, a doctor should have confirmed that your headache is due to a&nbsp;migraine&nbsp;and not to any other problem.<\/p>\n\n\n\n<p>Talk to your doctor before using Oriptan if any of the following apply to you:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are a heavy smoker or use nicotine replacement therapy, and especially<ul><li>if you are a man over 40 years, or<\/li><li>if you are a woman and have passed menopause.<\/li><\/ul><\/li><\/ul>\n\n\n\n<p>In very rare cases, severe heart problems have occurred after taking sumatriptan even though no signs of heart disease have been seen before.&nbsp;If any of the risk factors are right for you, it may mean that you are at greater risk of developing heart disease.&nbsp;Consult your doctor so that your heart function can be checked before sumatriptan is prescribed to you.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you have&nbsp;<strong>previously had seizures<\/strong>&nbsp;(epileptic seizures) or if you have other conditions that may make you more likely to have a seizure &#8211; such as a head injury or alcoholism.<\/li><li>if you have&nbsp;<strong>liver or kidney problems.<\/strong><\/li><li>if you are intolerant to any type of sugar.<\/li><li>if you are&nbsp;<strong>allergic to&nbsp;antibiotics<\/strong>&nbsp;called&nbsp;<strong>sulfonamides<\/strong>&nbsp;.&nbsp;In that case, you may also be allergic to sumatriptan.&nbsp;If you know that you are allergic to&nbsp;antibiotics&nbsp;but you are not sure if it is a sulfonamide, talk to your doctor or pharmacist before taking this medicine.<\/li><li>if you are taking antidepressants called&nbsp;<strong>SSRIs&nbsp;( selective<\/strong>&nbsp;serotonin reuptake inhibitors) or&nbsp;SNRIs&nbsp;(&nbsp;serotonin&nbsp;noradrenaline reuptake inhibitors).&nbsp;See also Other medicines and Oriptan below.<\/li><li>if you&nbsp;<strong>take sumatriptan often<\/strong>&nbsp;.&nbsp;Using sumatriptan too often can make your headache worse.&nbsp;Your doctor may recommend that you stop taking sumatriptan.<\/li><li>if you feel&nbsp;<strong>pain or tightness in the chest<\/strong>&nbsp;after taking sumatriptan.&nbsp;These symptoms can be intense but they usually go away quickly.&nbsp;If they do not go away quickly or if they get worse,&nbsp;<strong>seek medical help immediately.<\/strong><\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Oriptan<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.\u00a0This includes any herbal products, supplements such as\u00a0vitamins, iron or\u00a0calcium,\u00a0or medicines that you have purchased without a prescription.<\/p>\n\n\n\n<p>Some medicines should not be taken with Oriptan and others may cause&nbsp;side effects&nbsp;if taken with Oriptan.&nbsp;<strong>You must tell your doctor if you are taking:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>ergotamine<\/strong>&nbsp;which is also used to treat<strong>&nbsp;migraines<\/strong>&nbsp;, or similar medicines like methysergide maleate.&nbsp;Do not take Oriptan while taking these medicines.&nbsp;Stop taking these medicines for at least 24 hours before taking Oriptan.&nbsp;Do not take them again until at least 6 hours after taking Oriptan.<\/li><li>or any triptan or 5&nbsp;&#8211;&nbsp;HT&nbsp;<sub>1&nbsp;<\/sub>agonist&nbsp;(eg naratriptan, sumatriptan, rizatriptan, eletriptan, almotriptan or zolmitriptan).&nbsp;Do not take Oriptan while taking these medicines.&nbsp;Stop taking these medicines for at least 24 hours before taking Oriptan.&nbsp;Do not take them again until at least 24 hours after taking Oriptan.<\/li><li><strong>MAO inhibitors<\/strong>&nbsp;used to treat<strong>&nbsp;depression<\/strong>&nbsp;.&nbsp;Do not take Oriptan if you have been taking&nbsp;MAOIs&nbsp;for the past 2 weeks.<\/li><li><strong>SSRIs<\/strong>&nbsp;and<strong>&nbsp;SNRIs<\/strong>&nbsp;used to treat<strong>&nbsp;depression<\/strong>&nbsp;.&nbsp;Concomitant use of Oriptan and these medicines can cause serotonergic syndrome (a collection of symptoms that may include restlessness, confusion, sweating, hallucinations, increased reflexes, muscle twitching, tremors, increased heart rate and tremors).&nbsp;Tell your doctor immediately if you are affected in this way.<\/li><li>St. John&#8217;s wort&nbsp;(Hypericum perforatum).&nbsp;Using herbal remedies containing St. John&#8217;s&nbsp;wort&nbsp;with Oriptan may increase the risk of&nbsp;side effects&nbsp;.<\/li><li>lithium, a drug used to treat manic \/ depressive (bipolar) disorder.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, breastfeeding and fertility<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<\/p>\n\n\n\n<p><em>Pregnancy:<\/em><\/p>\n\n\n\n<p>If you are pregnant or think you may be pregnant, talk to your doctor before taking Oriptan.\u00a0There is only limited information on the safety of Oriptan in pregnant women, but to date, there is no evidence of an increased risk of birth defects.\u00a0Your doctor will discuss with you whether or not to use Oriptan during your pregnancy.<\/p>\n\n\n\n<p><em>Breast-feeding:<\/em><\/p>\n\n\n\n<p>Do not breastfeed your baby within 12 hours of taking Oriptan.\u00a0Breast milk pumped out during these 12 hours should be discarded and not given to your baby.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Migraine&nbsp;or treatment with Oriptan may make you drowsy.&nbsp;Do not drive or use any tools or machines if you are affected.<\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened vigilance.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects.\u00a0Descriptions of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Oriptan contains lactose<\/h2>\n\n\n\n<p>This medicine contains 176.3 mg\u00a0of lactose.\u00a0If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.<\/p>\n\n\n\n<p><strong>Other ingredients<\/strong><\/p>\n\n\n\n<p>This medicine contains less than 1 mmol (23 mg)&nbsp;sodium&nbsp;per tablet, ie essentially &#8216;sodium-free&#8217;.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to use Oriptan<\/h2>\n\n\n\n<p>Always take this medicine exactly as described in this leaflet or as your doctor or pharmacist has told you.\u00a0Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>It is best to take Oriptan as early as possible during a migraine attack, but can also be taken during an ongoing attack.<\/li><li>Do not take Oriptan to prevent a migraine attack, take it only after you start to feel migraine symptoms.<\/li><\/ul>\n\n\n\n<p><em>Adults<\/em><\/p>\n\n\n\n<p>The recommended&nbsp;dose&nbsp;is a 50 mg tablet for migraine attacks, which should be swallowed whole with water.&nbsp;do not take more than 100 mg during the same migraine attack.<\/p>\n\n\n\n<p>You must contact a doctor if the symptoms worsen or do not improve within 3 days.<\/p>\n\n\n\n<p><em>Children and young people under 18 years of age<\/em><\/p>\n\n\n\n<p>Oriptan is not recommended for children under 18 years of age.<\/p>\n\n\n\n<p><em>Older people (over 65 years)<\/em><\/p>\n\n\n\n<p>Oriptan is not recommended for people over 65 years of age.<\/p>\n\n\n\n<p><strong>If your symptoms start to come back<\/strong><\/p>\n\n\n\n<p>If migraine symptoms are relieved after the first\u00a0dose\u00a0(50 mg) but recur later, an additional 50 mg may be taken.\u00a0You must wait at least 2 hours after taking the first\u00a0dose\u00a0before you can take the second\u00a0dose.\u00a0Maximum 100 mg over 24 hours.<\/p>\n\n\n\n<p><strong>If the first tablet has no effect<\/strong><\/p>\n\n\n\n<p>Do not take a second tablet of Oriptan or any other sumatriptan preparation for the same attack.\u00a0If the first tablet has no effect, you can take other painkillers such as\u00a0paracetamol,\u00a0<a href=\"https:\/\/zeepedia.com\/medical\/medicines\/tiplo-citrus\/\">acetylsalicylic acid<\/a>,\u00a0or non-steroidal anti-inflammatory drugs.\u00a0Oriptan can still be taken in the next attack.<\/p>\n\n\n\n<p>If Oriptan does not give you relief, it may mean that you do not have a\u00a0migraine.\u00a0Ask your doctor for advice.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you take more Oriptan than you should<\/h2>\n\n\n\n<p><br>Do not take more than two 50 mg tablets (100 mg in total) for 24 hours.&nbsp;Excessive intake of Oriptan can make you sick.&nbsp;The overdose symptoms are the same as those listed in section 4 \u201cPossible side effects\u201d.<\/p>\n\n\n\n<p>If you have ingested too much medicine or if e.g.\u00a0If a child has ingested the medicine by mistake, contact a doctor or hospital for risk assessment and advice.<\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p><strong>Allergic reactions<\/strong><\/p>\n\n\n\n<p>No known frequency&nbsp;<em>(can not be calculated from the available data):<\/em><\/p>\n\n\n\n<p>Allergic skin reactions: Skin rash with red spots or hives (skin lumps).\u00a0Anaphylactic reaction\u00a0(Severe\u00a0allergic reaction\u00a0with swelling of eg eyelids, face or lips, sudden breathing problems, palpitations, pressure over the chest, or total collapse).<\/p>\n\n\n\n<p>If allergic reactions occur,\u00a0<strong>stop taking Oriptan<\/strong>.\u00a0If the reaction is severe,\u00a0<strong>seek medical attention immediately.<\/strong><\/p>\n\n\n\n<p><strong>Other possible&nbsp;side&nbsp;effects<\/strong><\/p>\n\n\n\n<p>Common&nbsp;<em>(affects 1 in 100 to 1 of 10 users):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Ant crawling, dizziness, drowsiness, unusual sensation<\/li><li>Transient increase in&nbsp;blood pressure&nbsp;(occurs shortly after taking the drug), feeling hot<\/li><li>Breathing difficulties<\/li><li>Nausea, vomiting<\/li><li>Feeling of heaviness, muscle pain<\/li><li>Pain, heat or feeling of cold, pressure or tightness.&nbsp;These symptoms are generally transient and can occur in any part of the body, including the chest and neck.&nbsp;Feeling weak, tired.<\/li><\/ul>\n\n\n\n<p>Very rare&nbsp;<em>(affects less than 1 user in 10,000):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Minor disturbances in liver function tests have sometimes been observed.<\/li><\/ul>\n\n\n\n<p>No known frequency&nbsp;<em>(can not be calculated from the available data):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Anxiety<\/li><li>Seizures (epileptic seizures), involuntary movements, tremors, involuntary eye movements (&nbsp;nystagmus&nbsp;)<\/li><li>Vision problems such as flicker, impaired vision, vision loss (these can also be due to the migraine attack itself)<\/li><li>Heart problems in the form of changes in heart rhythm (may beat faster, slower or change rhythm), chest pain (angina) or heart attack<\/li><li>Low&nbsp;blood pressure&nbsp;, Raynaud&#8217;s syndrome (a condition in which fingers and toes become whitish and numb)<\/li><li>Colon inflammation (which is felt in the form of pain in the far left of the abdomen or bloody diarrhea), diarrhea<\/li><li>Abundant sweating<\/li><li>Neck stiffness, joint pain<\/li><li>If you have recently been injured or if you have an&nbsp;inflammation&nbsp;(such as rheumatism or&nbsp;inflammation&nbsp;of the colon), you may experience pain or worsening pain at the site of the injury or&nbsp;inflammation&nbsp;.<\/li><li>Difficulty swallowing.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Oriptan<\/h2>\n\n\n\n<p>Keep out of sight and reach of children.<\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the carton after EXP. The expiry date refers to the last day of that month.<\/p>\n\n\n\n<p>Do not store above 25 \u00b0 C.&nbsp;Store in the original package.<\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the pack and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is sumatriptan 50 mg as sumatriptan succinate.<\/li><li>Other ingredients are:<em>Tablet core<\/em>&nbsp;:&nbsp;lactose monohydrate&nbsp;and&nbsp;lactose&nbsp;, croscarmellose sodium, microcrystalline cellulose, magnesium stearate<em>Film coating<\/em>&nbsp;:&nbsp;lactose monohydrate&nbsp;, mannitol, titanium dioxide (E 171), triacetin, talc.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and contents of the pack<\/h2>\n\n\n\n<p><em>50 mg film-coated tablet:<\/em><\/p>\n\n\n\n<p>Round, white, film-coated tablets, marked with \u201cRDY\u201d on one side and \u201c292\u201d on the other.<\/p>\n\n\n\n<p>Pack size: 2 tablets.<\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p><strong>Marketing Authorisation Holder<\/strong><\/p>\n\n\n\n<p>Orion Corporation<\/p>\n\n\n\n<p>Orionintie 1<\/p>\n\n\n\n<p>FI-02200 Espoo<\/p>\n\n\n\n<p>Finland<\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>Orion Corporation, Orion Pharma<\/p>\n\n\n\n<p>Orionintie 1<\/p>\n\n\n\n<p>FI-02200 Espoo<\/p>\n\n\n\n<p>Finland<\/p>\n\n\n\n<p>For further information on this medicine, please contact your local representative:<\/p>\n\n\n\n<p>Orion Pharma AB, Danderyd, medinfo@orionpharma.com<\/p>\n\n\n\n<p><strong>This medicinal product is authorized under the European Economic Area under the names<\/strong><\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td>Finland, Sweden<\/td><td>Oriptan<\/td><\/tr><tr><td>Poland, Czech Republic<\/td><td>Framing<\/td><\/tr><tr><td>Hungary<\/td><td>Sumatriptan Orion<\/td><\/tr><\/tbody><\/table><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>Each tablet contains a single dose of sumatriptan and belongs to a group of medicines called triptans (also called 5-HT1 receptor agonists ).<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,18526],"tags":[20222,13069,20217,20220,20221,13065,13070,13068,20218,13066,20219,13067],"class_list":["post-19940","post","type-post","status-publish","format-standard","hentry","category-medicines","category-o","tag-benefits-of-oriptan","tag-benefits-of-sumatriptan","tag-oriptan","tag-oriptan-side-effects","tag-oriptan-tablet","tag-sumatriptan","tag-sumatriptan-side-effects","tag-sumatriptan-tablet","tag-what-is-oriptan","tag-what-is-sumatriptan","tag-what-oriptan-is-used-for","tag-what-sumatriptan-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/19940","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=19940"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/19940\/revisions"}],"predecessor-version":[{"id":19973,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/19940\/revisions\/19973"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=19940"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=19940"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=19940"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}