{"id":19919,"date":"2022-03-21T11:31:13","date_gmt":"2022-03-21T11:31:13","guid":{"rendered":"https:\/\/zeepedia.com\/?p=19919"},"modified":"2022-03-22T11:33:22","modified_gmt":"2022-03-22T11:33:22","slug":"oralin","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/oralin\/","title":{"rendered":"Oralin – Sertraline uses, dose and side effects"},"content":{"rendered":"\n
What Oralin is and what it is used for<\/h2>\n\n\n\n
The active substance in Oralin is\u00a0sertraline.\u00a0Oralin belongs to a group of medicines called\u00a0SSRIs\u00a0(selective serotonin reuptake inhibitors).\u00a0These drugs are used to treat depression and\/or anxiety disorders.<\/p>\n\n\n\n
Oralin can be used to treat<\/p>\n\n\n\n
– depression and prevention of recurrent depression (in adults)<\/p>\n\n\n\n
– social phobia (in adults)<\/p>\n\n\n\n
– post-traumatic stress disorder (PTSD) (in adults)<\/p>\n\n\n\n
– panic disorder (in adults)<\/p>\n\n\n\n
obsessive-compulsive disorder (OCD) (in adults, as well as children and adolescents in the age group 6-17 years).<\/p>\n\n\n\n
Depression is a clinical illness with symptoms such as feeling sad, unable to sleep properly, or enjoying life as usual.<\/p>\n\n\n\n
Obsessive-compulsive disorder and panic disorder are diseases that are linked to anxiety with symptoms such as constant discomfort from fixations (obsessions), which means that you have to repeat different rituals (compulsion).<\/p>\n\n\n\n
Post-traumatic stress disorder is a condition that can occur after a very emotionally traumatic experience, with some symptoms similar to depression and anxiety. Social phobia (social anxiety syndrome) is a disease that is linked to anxiety. The disease is characterized by feelings of intense anxiety or anguish in social situations (eg, talking to strangers, speaking in front of groups of people, eating or drinking in front of other people, or worrying about perhaps behaving embarrassingly).<\/p>\n\n\n\n
Your doctor has decided that this medicine is suitable for treating your illness.<\/p>\n\n\n\n
Ask your doctor if you are not sure why you have been given Oralin.<\/p>\n\n\n\n
Sertraline\u00a0contained in Oralin may also be approved for the treatment of other conditions not mentioned in this leaflet.\u00a0Ask your doctor, pharmacist, or other healthcare professional if you have any further questions, and always follow their instructions.<\/p>\n\n\n\n
What you need to know before using Oralin<\/h2>\n\n\n\n
Do not take Oralin:<\/h2>\n\n\n\n
if you are allergic to sertraline or any of the other ingredients of this medicine (listed in section 6).<\/li>
if you are taking or have taken medicines called monoamine oxidase inhibitors ( MAOIs ) (eg selegiline , moclobemide) or medicines similar to MAOIs (eg linezolid). If you stop taking sertraline , you must wait at least 1 week before starting treatment with an MAOI . If you stop taking an MAOI , you must wait at least 2 weeks before you can start treatment with sertraline .<\/li>
if you are taking a medicine called pimozide (a medicine for mental illness such as psychosis ).<\/li><\/ul>\n\n\n\n
Warnings and cautions<\/h2>\n\n\n\n
Talk to your doctor or pharmacist before taking Oralin.<\/em><\/p>\n\n\n\n
Not all medicines are suitable for everyone. Tell your doctor before taking Oralin if you have or have ever had any of the following:<\/p>\n\n\n\n
If you have epilepsy (seizures) or if you have had seizures in the past. If you have a seizure, contact your doctor immediately.<\/li>
If you have a history of mania and depression ( bipolar disorder ) or schizophrenia. If you have a manic period, contact your doctor immediately.<\/li>
If you have or have previously had thoughts of harming yourself or committing suicide (see below “Suicidal thoughts and worsening of your depression or anxiety disorder”).<\/li>
If you have serotonergic syndrome. In rare cases, this syndrome may occur when you take certain other medicines at the same time as sertraline . (The symptoms of serotonergic syndrome are described in section 4, \u201cPossible side effects\u201d). Your doctor has told you if you have had this before.<\/li>
If you are taking medicines containing buprenorphine. If these medicines are used together with Oralin, this can lead to serotonergic syndrome, a condition that can be life-threatening (see “Other medicines and Oralin”).<\/li>
If you have low sodium levels in your blood, as this may occur when treated with Oralin. Also tell your doctor if you are taking certain medicines for high blood pressure , as such medicines can also change the levels of sodium in your blood.<\/li>
If you are older, because you may be at higher risk of getting low sodium levels in your blood (see above).<\/li>
If you have liver disease. Your doctor may decide that you should take a lower dose of Oralin.<\/li>
If you have diabetes . Blood sugar levels may be affected due to Oralin and your diabetes medicine may need to be adjusted.<\/li>
If you have a history of bleeding disorders or if you are pregnant (see ‘Pregnancy, breast-feeding and fertility’, or if you have taken medicines that thin the blood (eg acetylsalicylic acid or warfarin ) or that may increase the risk of bleeding.<\/li>
If you are a child or young person under 18 years of age. Oralin should only be given to children and adolescents aged 6-17 years if they suffer from obsessive-compulsive disorder (OCD). If you are being treated for this disease, your doctor will want to monitor you closely (see “Children and Adolescents” below).<\/li>
If you receive electrical treatment (so-called electroconvulsive treatment, ECT).<\/li>
If you have eye problems, such as certain types of glaucoma (increased pressure in the eye).<\/li>
If you have been told by an examination of your heart that you have an abnormal ECG ( electrocardiogram ) called an extended QT interval .<\/li>
If you have heart disease, low potassium or low magnesium levels in the blood, cases of prolonged QT interval in the family, low heart rate or at the same time using drugs that prolong QT interval .<\/li><\/ul>\n\n\n\n
Drugs such as Oralin (so-called SSRIs \/ SNRIs) can cause symptoms of sexual dysfunction (see section 4). In some cases, these symptoms have persisted after discontinuation of treatment.<\/p>\n\n\n\n
Restlessness\/akathisia<\/strong> The use of\u00a0sertraline\u00a0has been linked to a painful restlessness and need to move, often unable to sit or stand still (\u00a0akathisia\u00a0).\u00a0This usually occurs during the first weeks of treatment.\u00a0Increasing\u00a0dose\u00a0one can be harmful, so if you develop such symptoms, you should consult your doctor.<\/p>\n\n\n\n
Discontinuation<\/strong> reactions Adverse reactions\u00a0associated with discontinuation of treatment (discontinuation reactions) are common, especially if treatment is stopped abruptly (see section 3 If you stop taking Oralin and section 4, Possible\u00a0side effects\u00a0).\u00a0The risk of getting withdrawal symptoms depends on how long you have been treated,\u00a0dosage\u00a0one, and how quickly\u00a0dose\u00a0one is stepped down.\u00a0In general, these symptoms are mild to moderate, but for some patients, they can be severe.\u00a0The symptoms usually appear within the first few days after stopping treatment and usually disappear on their own or subside within 2 weeks.\u00a0In some patients, they may sit for longer (2-3 months or more).\u00a0About the treatment with\u00a0sertraline should be discontinued it is recommended that the\u00a0dose\u00a0be reduced gradually over several weeks or months, you should always discuss with your doctor how you can discontinue treatment in the best way.<\/p>\n\n\n\n
If you start to feel worse and have thoughts of harming yourself<\/strong> You who are depressed and\/or suffer from worry\/anxiety can sometimes have thoughts of harming yourself or committing suicide.\u00a0These symptoms may worsen when you start taking antidepressants, as it takes time for a drug of this type to take effect, usually about 2 weeks, sometimes longer.<\/p>\n\n\n\n
These thoughts may be common:<\/strong><\/p>\n\n\n\n
if you have previously had thoughts of harming yourself or committing suicide,<\/li>
if you are younger than 25 years. Studies have shown that young adults (younger than 25 years) with mental illness who are treated with antidepressant drugs have an increased risk of suicidal thoughts and thoughts of harming themselves.<\/li><\/ul>\n\n\n\n
Contact a doctor as soon as possible or go to the nearest hospital if you have thoughts of injuring yourself or committing suicide.<\/p>\n\n\n\n
It can be helpful to tell a relative or close friend that you are depressed and\/or suffering from anxiety.\u00a0Feel free to ask them to read this leaflet.\u00a0You can also ask them to tell you if they think you are feeling worse or if they think your behavior is changing.<\/p>\n\n\n\n
Children and adolescents<\/strong> Sertraline\u00a0should not normally be used in the treatment of children and adolescents under 18 years of age, except in patients with obsessive-compulsive disorder (OCD).\u00a0The risk of\u00a0side effects such as suicide attempts, thoughts of harming or committing suicide (suicidal thoughts) and hostility (mainly aggression, defiance, and anger) are greater in people under the age of 18 when they take drugs of this type.\u00a0Despite this, Oralin can be prescribed by a doctor to patients under 18 years of age, if the doctor deems it appropriate.\u00a0If a doctor has prescribed Oralin for you and you are under 18 and you want to discuss this, contact your doctor.\u00a0You should also tell your doctor if you notice any of the above symptoms or if these symptoms worsen when you take Oralin.\u00a0In addition, the long-term effects of Oralin on the growth, maturation, and development of learning ability (cognitive ability) and behavior have not yet been established in this age group.<\/p>\n\n\n\n
Other medicines and Oralin<\/strong><\/p>\n\n\n\n
Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.<\/p>\n\n\n\n
Some medicines may affect the effect of Oralin, or Oralin may reduce the effect of other medicines taken at the same time.<\/p>\n\n\n\n
Taking Oralin with the following medicines can cause serious side effects:<\/strong><\/p>\n\n\n\n
Drugs called monoamine oxidase inhibitors ( MAOIs ) such as moclobemide (for depression) and selegiline (for Parkinson’s disease ), antibiotic et linezolid and methylene blue (for the treatment of high levels of methemoglobin in the blood). Do not use Oralin with these medicines.<\/li>
Medicines for mental illnesses such as psychosis (pimozide). Do not use Oralin with pimozide.<\/li>
Some medicines can aggravate the side effects of Oralin and in some cases can cause very serious reactions. Do not take any other medicines while you are taking Oralin without first talking to your doctor, especially: medicines containing buprenorphine. These medicines can affect or be affected by Oralin and you may experience symptoms such as involuntary rhythmic muscle twitching, even in the muscles that control eye movements, agitation, hallucinations, coma , heavy sweating, tremors, increased reflexes, tense muscles and body temperature above 38 \u00b0 C. Contact your doctor if you experience such symptoms.<\/li><\/ul>\n\n\n\n
Talk to your doctor if you are taking any of the following medicines:<\/strong><\/p>\n\n\n\n
Medicines containing amphetamines (used to treat attention deficit hyperactivity disorder, narcolepsy and obesity).<\/li>
Herbal medicine that contains St. John’s wort ( Hypericum perforatum<\/em> ). The effect of St. John’s wort can be for 1-2 weeks.<\/li>
Products that contain the amino acid tryptophan.<\/li>