{"id":19866,"date":"2022-03-19T11:18:59","date_gmt":"2022-03-19T11:18:59","guid":{"rendered":"https:\/\/zeepedia.com\/?p=19866"},"modified":"2022-03-21T11:28:14","modified_gmt":"2022-03-21T11:28:14","slug":"oprymea","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/oprymea\/","title":{"rendered":"Oprymea &#8211; Pramipexole uses, dose and side effects"},"content":{"rendered":"\n<p>0.26 mg, 0.52 mg, 1.05 mg, 1.57 mg, 2.1 mg, 2.62 mg and 3.15 mg&nbsp;prolonged-release tablets<br>pramipexole<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Oprymea is and what it is used for<\/h2>\n\n\n\n<p>Oprymea contains the active substance pramipexole and belongs to a group of medicines called dopamine agonists, which stimulate the dopamine receptors in the brain.&nbsp;By stimulating dopamine receptors, nerve impulses are triggered in the brain that can help control the body&#8217;s movements.<\/p>\n\n\n\n<p>Oprymea is used to treat the symptoms of&nbsp;Parkinson&#8217;s disease&nbsp;in adults.&nbsp;It can be used alone or in combination with&nbsp;levodopa&nbsp;(another medicine for&nbsp;Parkinson&#8217;s disease&nbsp;).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before you use Oprymea<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Oprymea<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to pramipexole or any of the other ingredients of this medicine (listed in section 6).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor before taking Oprymea.&nbsp;Tell your doctor if you have (have had) or have any symptoms, especially any of the following:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>kidney disease<\/li><li>hallucinations (seeing, hearing or perceiving things that do not exist).&nbsp;Most hallucinations are visual hallucinations.<\/li><li>dyskinesia&nbsp;(eg abnormal, uncontrolled movements of the arms and legs).&nbsp;If you have advanced&nbsp;Parkinson&#8217;s disease&nbsp;and are also taking&nbsp;levodopa&nbsp;, you may develop&nbsp;dyskinesia&nbsp;during the titration period with Oprymea.<\/li><li>dystonia&nbsp;(inability to keep body and neck straight and upright (&nbsp;axial&nbsp;dystonia&nbsp;)).&nbsp;In particular, you may experience forward bending of the head and neck (also known as antecollis), forward bending of the lumbar spine (also known as camptochormia) or lateral bending of the back (also known as pleurototonus or Pisa syndrome).&nbsp;If this happens, your doctor may want to change your medication.<\/li><li>drowsiness and episodes of sudden drowsiness<\/li><li>psychosis&nbsp;(eg comparable to symptoms of schizophrenia)<\/li><li>visual impairment.&nbsp;Your eyes should be examined regularly during treatment with Oprymea.<\/li><li>severe cardiovascular disease.&nbsp;You will need to check&nbsp;your blood pressure&nbsp;regularly, especially at the beginning of treatment.&nbsp;The reason is that you want to avoid a drop in blood pressure when you stand up.<\/li><\/ul>\n\n\n\n<p>Tell your doctor if you or your family\/caregiver notices that you are developing impulses or want to behave in a way that is unusual for you and that you cannot resist the impulse, the drive, or the temptation to perform activities that may harm yourself or others.\u00a0This is called impaired impulse control and can include behavior such as gambling addiction, excessive eating or buying behavior, abnormally high sex drive, or increased preoccupation with constant thoughts of sex or sexual feelings.\u00a0Your doctor may need to adjust your\u00a0dose\u00a0or stop your medication.<\/p>\n\n\n\n<p>Tell your doctor if you or your family\/caregiver notices that you are developing mania (feeling upset, elated, or overexcited) or\u00a0delirium\u00a0(decreased consciousness, confusion, or loss of reality).\u00a0Your doctor may need to adjust your\u00a0dose\u00a0or stop your medication.\u00a0<\/p>\n\n\n\n<p>Tell your doctor if you get symptoms such as depression,\u00a0apathy, anxiety, fatigue, sweating, or pain after stopping taking or reducing the\u00a0dose\u00a0of Oprymea.\u00a0If the problems persist for more than a few weeks, your doctor may need to adjust your treatment.<\/p>\n\n\n\n<p>Oprymea&nbsp;prolonged-release tablet&nbsp;is a specially designed tablet from which the active substance is gradually released after the tablet has been swallowed.&nbsp;Parts of the tablets can sometimes pass and be seen in the stool (&nbsp;feces&nbsp;) and may look like whole tablets.&nbsp;Tell your doctor if you find parts of tablets in your stool.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children and young people<\/h2>\n\n\n\n<p>Oprymea is not recommended for use in children and adolescents below 18 years.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Oprymea<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.\u00a0This also applies to medicines, herbal medicines, health foods, or dietary supplements that you have received without a prescription.<\/p>\n\n\n\n<p>Avoid taking Oprymea with antipsychotic drugs.<\/p>\n\n\n\n<p>Be careful if you are taking any of the following medicines:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>cimetidine (for the treatment of excess stomach acid and&nbsp;ulcers&nbsp;)<\/li><li>amantadine (which can be used to treat&nbsp;Parkinson&#8217;s disease&nbsp;)<\/li><li>mexiletine (for the treatment of irregular heartbeat, a condition called ventricular arrhythmia)<\/li><li>zidovudine (which can be used to treat&nbsp;HIV&nbsp;, an immunodeficiency disease)<\/li><li>cisplatin (for the treatment of various types of cancer)<\/li><li>quinine (which can be used to prevent painful nocturnal calf cramps and to treat a type of&nbsp;malaria&nbsp;known as falciparum malaria)<\/li><li>procainamide&nbsp;(for the treatment of irregular heartbeats)<\/li><\/ul>\n\n\n\n<p>If you are taking\u00a0levodopa, the\u00a0dose\u00a0of one of\u00a0levodopa\u00a0should be\u00a0reduced when you start treatment with Oprymea.<\/p>\n\n\n\n<p>Be careful when using drugs that have a sedative effect or when consuming alcoholic beverages.&nbsp;In these cases, Oprymea may affect your ability to drive and use machines.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Oprymea with food, drink and alcohol<\/h2>\n\n\n\n<p>Be careful with alcoholic beverages during treatment with Oprymea.<\/p>\n\n\n\n<p>Oprymea can be taken with or without food.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, breastfeeding and fertility<\/h2>\n\n\n\n<p>If you are pregnant or breast-feeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.\u00a0Your doctor will then discuss with you whether to continue using Oprymea.<\/p>\n\n\n\n<p>The effect of Oprymea on the unborn baby is unknown.&nbsp;Therefore, you should not take Oprymea if you are pregnant unless your doctor advises you to do so.<\/p>\n\n\n\n<p>Oprymea should not be used during breast-feeding.&nbsp;Oprymea may reduce the production of breast milk.&nbsp;It can also pass to the breast milk and reach your baby.&nbsp;If the use of Oprymea is necessary, breast-feeding should be discontinued.<\/p>\n\n\n\n<p>Ask your doctor or pharmacist for advice before taking any medicine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Oprymea can cause hallucinations (seeing, hearing, or perceiving things that do not exist).\u00a0If you experience this, do not drive or use any tools or machines.<\/p>\n\n\n\n<p>Oprymea is associated with drowsiness and episodes of sudden drowsiness, especially in patients with\u00a0Parkinson&#8217;s disease.\u00a0If you experience these\u00a0side effects, do not drive or use any tools or machines.\u00a0You should tell your doctor if this happens.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to use Oprymea<\/h2>\n\n\n\n<p>Always take this medicine exactly as your doctor or pharmacist has told you.\u00a0Ask your doctor or pharmacist if you are unsure.\u00a0Your doctor will inform you about the correct\u00a0dosage.<\/p>\n\n\n\n<p>Take Oprymea&nbsp;prolonged-release tablet&nbsp;only once a day at about the same time each day.<\/p>\n\n\n\n<p>You can take Oprymea with or without food.&nbsp;The tablets should be swallowed whole with water.<\/p>\n\n\n\n<figure class=\"wp-block-image\"><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=20130208000077#\" rel=\"noopener\"><img decoding=\"async\" src=\"https:\/\/www.fass.se\/res\/RootMedia\/KRKA\/Media\/Oprymea20SR\/Oprymea20SR.jpg\" alt=\"The prolonged-release tablet must not be chewed, divided or crushed.  If this still happens, there is a risk of overdose because the drug can be released too quickly in your body.\" title=\"The prolonged-release tablet must not be chewed, divided or crushed.  If this still happens, there is a risk of overdose because the drug can be released too quickly in your body.\"\/><\/a><\/figure>\n\n\n\n<p>Prolonged-release tablets\u00a0must not be chewed, divided, or crushed.\u00a0If this should still happen, there is a risk of overdose because the drug can be released too quickly in your body.<\/p>\n\n\n\n<p>During the first week, the normal daily dose is 0.26 mg pramipexole.\u00a0Your doctor will increase the\u00a0dose\u00a0every five to seven days until your symptoms are under control (maintenance dose).<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><th scope=\"row\">Dose escalation schedule for Oprymea&nbsp;prolonged-release&nbsp;tablets<\/th><\/tr><tr><td>Week<\/td><td>Daily dose (mg)<\/td><td>Number of tablets<\/td><\/tr><tr><td>1<\/td><td>0.26<\/td><td>An Oprymea 0.26 mg\u00a0prolonged-release tablet.<\/td><\/tr><tr><td>2<\/td><td>0.52<\/td><td>An Oprymea 0.52 mg&nbsp;prolonged-release tabletORtwo Oprymea 0.26 mg&nbsp;prolonged-release tablets&nbsp;are.<\/td><\/tr><tr><td>3<\/td><td>1.05<\/td><td>An Oprymea 1.05 mg&nbsp;prolonged-release tabletORtwo Oprymea 0.52 mg&nbsp;prolonged-release&nbsp;tabletsORfour Oprymea 0.26 mg&nbsp;prolonged-release tablets&nbsp;.<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p>The usual maintenance dose is 1.05 mg daily.\u00a0However, does\u00a0one may need to be increased further.\u00a0Your doctor may increase the\u00a0dose\u00a0by up to a maximum of 3.15 mg pramipexole per day, if necessary.\u00a0A lower maintenance dose of an Oprymea 0.26 mg\u00a0prolonged-release tablet\u00a0per day is also possible.<\/p>\n\n\n\n<p><em>Patients with kidney disease<\/em><\/p>\n\n\n\n<p>If you have any kidney disease, your doctor may recommend that you take the usual starting dose of 0.26 mg\u00a0prolonged-release tablet, only every other day for the first week.\u00a0After that, your doctor may increase the dosing frequency to a 0.26 mg\u00a0prolonged-release tablet\u00a0every day.\u00a0If further dose escalation is required, your doctor may adjust the\u00a0dose\u00a0one step at a time with 0.26 mg pramipexole with each increase.<\/p>\n\n\n\n<p>In severe kidney disease, your doctor may need to switch to another medicine with pramipexole.&nbsp;If your kidney problems worsen during treatment, you should contact a doctor as soon as possible.<\/p>\n\n\n\n<p><em>If you are switching from Oprymea tablets (with immediate-release\u00a0)<\/em><\/p>\n\n\n\n<p>Your doctor will base your\u00a0dose\u00a0of Oprymea\u00a0prolonged-release tablet\u00a0on the\u00a0dose\u00a0you took of Oprymea tablets (immediate-release\u00a0).<\/p>\n\n\n\n<p>Take your Oprymea tablets (immediate\u00a0release\u00a0) as usual the day before you change.\u00a0Then take your Oprymea\u00a0prolonged-release tablets\u00a0the next morning but no more Oprymea tablets (with immediate-release\u00a0).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you use more Oprymea than you should&nbsp;<\/h2>\n\n\n\n<p>If you accidentally take too many tablets,<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>contact your doctor or nearest emergency department immediately for advice<\/li><li>you may experience vomiting, inability to stand still, or any of the&nbsp;side effects&nbsp;described in section 4 (Possible&nbsp;side effects&nbsp;)<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to use Oprymea<\/h2>\n\n\n\n<p>If you forget to take a&nbsp;dose&nbsp;of Oprymea, but remember within 12 hours, take your tablet at once and then take the next one at the usual time.<\/p>\n\n\n\n<p>If you miss a\u00a0dose\u00a0for more than 12 hours, take the next\u00a0dose\u00a0at the usual time.\u00a0Do not take a double\u00a0dose\u00a0to make up for a forgotten\u00a0dose.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop using Oprymea<\/h2>\n\n\n\n<p>Do not stop taking Oprymea without talking to your doctor first.\u00a0If you need to stop treatment, your doctor will reduce the\u00a0dose\u00a0gradually.\u00a0This reduces the risk of worsening symptoms.<\/p>\n\n\n\n<p>If you have Parkinson&#8217;s disease, do not stop taking Oprymea abruptly.\u00a0A sudden interruption can cause you to develop a disease condition called a malignant neuroleptic syndrome, this condition can pose a major health risk.\u00a0Symptoms include:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>akinesia&nbsp;(loss of muscle mobility)<\/li><li>stiff muscles<\/li><li>fever<\/li><li>varying&nbsp;blood pressure<\/li><li>tachycardia&nbsp;(increased heart rate)<\/li><li>confusion<\/li><li>decreased level of consciousness (eg&nbsp;coma&nbsp;)<\/li><\/ul>\n\n\n\n<p>If you stop taking Oprymea or reduce your\u00a0dose, you may also develop a medical condition called withdrawal syndrome after treatment with a dopamine agonist.\u00a0Symptoms include depression,\u00a0apathy, anxiety, fatigue, sweating, or pain.\u00a0If you get these symptoms, consult a doctor.<\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.\u00a0Evaluation of these\u00a0side effects\u00a0is based on the following frequencies: <a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=20130208000077#\" rel=\"noopener\">Show larger<\/a><\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td>Very common:<\/td><td>may occur in more than 1 in 10 users<\/td><\/tr><tr><td>Usual:<\/td><td>may affect up to 1 in 10 users<\/td><\/tr><tr><td>Uncommon:<\/td><td>may affect up to 1 in 100 users<\/td><\/tr><tr><td>Rare:<\/td><td>can occur in up to 1 in 1,000 users<\/td><\/tr><tr><td>Very rare:<\/td><td>may affect up to 1 in 10,000 users<\/td><\/tr><tr><td>No known frequency<\/td><td>can not be calculated from available data<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p>You may experience the following side effects:<\/p>\n\n\n\n<p><strong>Very common:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Dyskinesia&nbsp;(abnormal involuntary movements)<\/li><li>Somnolence<\/li><li>Dizziness<\/li><li>Nausea<\/li><\/ul>\n\n\n\n<p><strong>Usual:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Strong need to behave in an unusual way<\/li><li>Hallucinations (abnormal vision, sound or sensations)<\/li><li>Confusion<\/li><li>Fatigue<\/li><li>Insomnia (insomnia)<\/li><li>Excess fluid, usually in the legs (peripheral&nbsp;edema&nbsp;)<\/li><li>Headache<\/li><li>Low&nbsp;blood pressure&nbsp;(&nbsp;hypotension&nbsp;)<\/li><li>Abnormal dreams<\/li><li>Constipation<\/li><li>Visual impairment<\/li><li>Vomiting<\/li><li>Weight loss including decreased appetite<\/li><\/ul>\n\n\n\n<p><strong>Uncommon:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Paranoia&nbsp;(eg excessive concern for their health)<\/li><li>Abnormal perception of reality<\/li><li>Excessive daytime sleepiness and sudden drowsiness<\/li><li>Memory loss (&nbsp;amnesia&nbsp;)<\/li><li>Hyperkinesia (inability to stand still)<\/li><li>Weight gain<\/li><li>Allergic reactions (eg rash,&nbsp;itching&nbsp;, hypersensitivity)<\/li><li>Fainting<\/li><li>Heart failure&nbsp;(heart problems that can cause shortness of breath and swollen ankles) *<\/li><li>Altered secretion of antidiuretic hormone *<\/li><li>Restlessness<\/li><li>Dyspnoea&nbsp;(difficulty breathing)<\/li><li>Hiccup<\/li><li>Pneumonia&nbsp;(&nbsp;pneumonia&nbsp;)<\/li><li>Inability to resist the impulse, drive or desire to perform an act that may be harmful to yourself and others, which may include:<ul><li>Strong impulse to play excessively despite serious personal consequences or consequences for the family.<\/li><li>Changed or increased sexual interest and behavior of significant problems for you or others, such as increased sexual drive.<\/li><li>Uncontrollable excessive buying behavior or wasting money.<\/li><li>Binge eating (eating large amounts of food for a short time) or compulsive eating (eating larger amounts of food than normal and more than is needed to satisfy hunger). *<\/li><\/ul><\/li><li>Delirium&nbsp;(decreased consciousness, confusion, loss of reality)<\/li><\/ul>\n\n\n\n<p><strong>Rare:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Mania (feeling upset, elated or overexcited)<\/li><\/ul>\n\n\n\n<p><strong>No known frequency:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>After discontinuation or reduction of Oprymea: depression,&nbsp;apathy&nbsp;, anxiety, fatigue, sweating or pain may occur (withdrawal syndrome after dopamine agonist treatment).<\/li><\/ul>\n\n\n\n<p><strong>Tell your doctor if you experience any of the above behaviors, he will discuss how to manage or reduce the symptoms.<\/strong><\/p>\n\n\n\n<p>For&nbsp;adverse reactions&nbsp;marked with *, an exact frequency estimate is not possible as these&nbsp;adverse reactions&nbsp;have not been observed in&nbsp;clinical trials&nbsp;in 2762 patients treated with pramipexole.&nbsp;The frequency is probably not higher than &#8220;less common&#8221;.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Oprymea<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the carton after EXP.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>Store in the original package.&nbsp;Moisture sensitive.<\/p>\n\n\n\n<p>No special temperature instructions.<\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the pack and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<p>&#8211; The active substance is pramipexole.&nbsp;Each&nbsp;prolonged-release tablet&nbsp;contains 0.26 mg, 0.52 mg, 1.05 mg, 1.57 mg, 2.1 mg, 2.62 mg or 3.15 mg pramipexole each corresponding to 0.375 mg, 0.75 mg, 1, 5 mg, 2.25 mg, 3 mg, 3.75 mg or 4.5 mg pramipexole dihydrochloride monohydrate.<\/p>\n\n\n\n<p>&#8211; The other ingredients are hypromellose, corn starch,\u00a0colloidal\u00a0anhydrous silicon, and magnesium stearate.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and contents of the pack<\/h2>\n\n\n\n<p>Oprymea 0.26 mg\u00a0prolonged-release tablets\u00a0are white or almost white, round (diameter 10 mm), slightly biconvex tablets marked with P1 on one side, with beveled edges and any spots.<\/p>\n\n\n\n<p>Oprymea 0.52 mg\u00a0prolonged-release tablets\u00a0are white or almost white, round (diameter 10 mm), slightly biconvex tablets marked with P2 on one side, with beveled edges and any spots.<\/p>\n\n\n\n<p>Oprymea 1.05 mg\u00a0prolonged-release tablets\u00a0are white or almost white, round (diameter 10 mm), slightly biconvex tablets marked with P3 on one side, with beveled edges and any spots.<\/p>\n\n\n\n<p>Oprymea 1.57 mg\u00a0prolonged-release tablets\u00a0are white or almost white, round (diameter 10 mm), slightly biconvex tablets marked with P12 on one side, with beveled edges and any spots.<\/p>\n\n\n\n<p>Oprymea 2.1 mg\u00a0prolonged-release tablets\u00a0are white or almost white, round (diameter 10 mm), slightly biconvex tablets marked with P4 on one side, with beveled edges and any spots.<\/p>\n\n\n\n<p>Oprymea 2.62 mg\u00a0prolonged-release tablets\u00a0are white or almost white, round (diameter 10 mm), slightly biconvex tablets marked with P13 on one side and 262 on the other side, with beveled edges and any spots.<\/p>\n\n\n\n<p>Oprymea 3.15 mg\u00a0prolonged-release tablets\u00a0are white or almost white, round (diameter 10 mm), slightly biconvex tablets marked with P5 on one side and 315 on the other side, with beveled edges and any spots.<\/p>\n\n\n\n<p>Cartons of 10, 30, 90, or 100 tablets in blister cards are available.<\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p><strong>Marketing Authorisation Holder<\/strong><\/p>\n\n\n\n<p>KRKA, dd, Novo mesto, \u0160marje\u0161ka cesta 6, 8501 Novo mesto, Slovenia<\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>KRKA, dd, Novo mesto, \u0160marje\u0161ka cesta 6, 8501 Novo mesto, Slovenia<\/p>\n\n\n\n<p>TAD Pharma GmbH, Heinz-Lohmann-Stra\u00dfe 5, 27472 Cuxhaven, Germany<\/p>\n\n\n\n<p><strong>Contact the representative of the marketing authorization holder to find out more about this medicine:<\/strong><\/p>\n\n\n\n<p>KRKA Sverige AB<\/p>\n\n\n\n<p>G\u00f6ta Ark 175<\/p>\n\n\n\n<p>118 72 Stockholm<\/p>\n\n\n\n<p>Tel: + 46 (0) 8 643 67 66 (SE)<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Oprymea contains the active substance pramipexole and belongs to a group of medicines called dopamine agonists, which stimulate the dopamine receptors in the brain. By stimulating dopamine receptors, nerve impulses are triggered in the brain that can help control the body&#8217;s movements.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,18526],"tags":[20159,20153,20154,20158,20157,5888,5890,5891,20155,5889,20156,20152],"class_list":["post-19866","post","type-post","status-publish","format-standard","hentry","category-medicines","category-o","tag-benefits-of-oprymea","tag-benefits-of-pramipexole","tag-oprymea","tag-oprymea-side-effects","tag-oprymea-tablet","tag-pramipexole","tag-pramipexole-side-effects","tag-pramipexole-tablet","tag-what-is-oprymea","tag-what-is-pramipexole","tag-what-oprymea-is-used-for","tag-what-pramipexole-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/19866","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=19866"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/19866\/revisions"}],"predecessor-version":[{"id":19912,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/19866\/revisions\/19912"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=19866"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=19866"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=19866"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}