Breast-feeding<\/em><\/p>\n\n\n\nChildren who are breastfed may be affected.\u00a0Ondansetron Hexal should not be used if you are breast-feeding other than on a\u00a0doctor’s prescription.<\/p>\n\n\n\n
Driving and using machines<\/h2>\n\n\n\n
Studies show that Ondansetron Hexal does not affect your ability to drive or use machines. However, some side effects (blurred vision, dizziness) may occur.<\/p>\n\n\n\n
You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects.\u00a0Descriptions of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n
Ondansterone Hexal contains sodium<\/h2>\n\n\n\n
This medicine contains less than 1 mmol\u00a0sodium\u00a0(23 mg) per\u00a0dose, ie essentially ‘sodium-free’.<\/p>\n\n\n\n
How to use Ondansetron Hexal<\/h2>\n\n\n\n
Always use this medicine exactly as your doctor or pharmacist has told you. Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n
Ondansetron Hexal is given by a doctor or nurse<\/p>\n\n\n\n
Nausea and vomiting associated with chemotherapy and radiation therapy:<\/strong><\/p>\n\n\n\nAdults:<\/em> The usual dose is 8 mg given as an injection or infusion before chemotherapy or radiation therapy. Thereafter, treatment is usually continued with ondansetron tablets.<\/p>\n\n\n\nOndansetron Hexal can also be given in the following ways in connection with severe nausea-inducing chemotherapy:<\/p>\n\n\n\n
- 8 mg given as an injection immediately before chemotherapy, possibly followed by an additional dose of 8 mg up to a maximum daily dose of 32 mg.<\/li>
- Alternatively, up to 16 mg is given as a continuous infusion for at least 15 minutes immediately before chemotherapy.<\/li><\/ul>\n\n\n\n
A single dose of more than 16 mg must not be given due to an increased risk of severe heart rhythm disturbances with a rapid, irregular heartbeat (see section 4).<\/p>\n\n\n\n
After 24 hours, the treatment is usually switched to ondansetron tablets.<\/p>\n\n\n\n
Older:<\/em><\/p>\n\n\n\nIn patients 75 years of age or older, the first intravenous dose of Ondansetron Hexal should not exceed 8 mg. This dose may be followed by two additional 8 mg intravenous doses given at least 4 hours apart. All intravenous doses should be given as a continuous infusion over at least 15 minutes.<\/p>\n\n\n\n
Children and adolescents (aged 6 months to 17 years):<\/em><\/p>\n\n\n\nDose one is individual and is calculated by the doctor based on the child’s weight or body surface area.<\/p>\n\n\n\n
Ondansetron Hexal is given as an injection immediately before chemotherapy and the dose should not exceed 8 mg. If dose one is calculated based on body weight, two additional intravenous doses may be given at 4-hour intervals. Oral dosing can be started 12 hours later and continued for up to 5 days. The total daily dose should not exceed the maximum adult dose of 32 mg.<\/p>\n\n\n\n
Nausea and vomiting after surgery:<\/strong><\/p>\n\n\n\nAdults, prevention and treatment:<\/em><\/p>\n\n\n\nThe usual dose is 4 mg one hour before anesthesia.<\/p>\n\n\n\n
Elderly, prevention and treatment:<\/em><\/p>\n\n\n\nExperience in the treatment of nausea after surgery in elderly patients is limited. However, Ondansetron Hexal is well tolerated by patients over 65 years of age in chemotherapy and radiation therapy<\/p>\n\n\n\n
Children and adolescents (aged 1 month to 17 years), prevention and treatment:<\/em><\/p>\n\n\n\nDose one is individual and is calculated by the doctor based on the weight of the child.<\/p>\n\n\n\n
A single dose of ondansetron is given as a slow\u00a0intravenous\u00a0injection\u00a0(for at least 30 seconds) at a maximum\u00a0dose\u00a0of 4 mg either before, during, or after anesthesia.<\/p>\n\n\n\n
Hepatic impairment:<\/em><\/p>\n\n\n\nThe daily dose should not exceed 8 mg if you have moderate to severe hepatic impairment.<\/p>\n\n\n\n
If you take more Ondansetron Hexal than you should<\/h2>\n\n\n\n
A doctor or nurse will give you or your child Ondansetron Hexal, so it is unlikely that you or your child will receive too much.\u00a0If you think you or your child have taken too much or missed a\u00a0dose, tell your doctor or nurse.<\/p>\n\n\n\n
Symptoms <\/em>of overdose:<\/em><\/p>\n\n\n\nBlurred vision, double vision, dizziness, headache, fatigue, fast or slow heartbeat, low\u00a0blood pressure, severe constipation, involuntary muscle cramps, muscle twitching, restlessness, overactivity, hallucinations are conceivable.<\/p>\n\n\n\n
Possible side effects<\/h2>\n\n\n\n
Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n
Contact a healthcare professional immediately if you get any of the following severe allergic reactions:<\/strong> <\/p>\n\n\n\n- hypersensitivity reaction with fever, rash, swelling and sometimes drop in blood pressure (anaphylactic shock , rare)<\/li>
- severe widespread skin damage (skin detachment of the epidermis and superficial mucous membranes), ( toxic epidermal necrolysis , very rare).<\/li><\/ul>\n\n\n\n
Other possible side effects:<\/strong><\/p>\n\n\n\nVery common<\/strong> (may affect more than 1 user in 10):<\/p>\n\n\n\n- headache.<\/li><\/ul>\n\n\n\n
Common<\/strong> (may affect up to 1 in 10 people):<\/p>\n\n\n\n- feeling of heat, hot flashes<\/li>
- constipation<\/li>
- local reactions at the injection site (for intravenous administration ).<\/li><\/ul>\n\n\n\n
Uncommon<\/strong> (may affect up to 1 in 100 people):<\/p>\n\n\n\n- movement disorders, involuntary muscle twitching, painful movements. Eye cramps when the eyes are forced in a certain direction, which can give a dizzy-like experience.<\/li>
- seizures<\/li>
- irregular heartbeat or slow heartbeat<\/li>
- chest pain<\/li>
- low blood pressure<\/li>
- hiccup<\/li>
- elevated liver values \u200b\u200bin liver function tests.<\/li><\/ul>\n\n\n\n
Rare<\/strong> (may affect up to 1 in 1,000 people):<\/p>\n\n\n\n- hypersensitivity reaction er<\/li>
- transient vision changes such as blurred vision (occurs mainly during injection therapy)<\/li>
- dizziness (with rapid injection administration).<\/li><\/ul>\n\n\n\n
Very rare<\/strong> (may affect up to 1 in 10,000 people):<\/p>\n\n\n\n- transient blindness, usually transient within 20 minutes (occurs mainly during injection therapy).<\/li><\/ul>\n\n\n\n
How to store Ondansetron Hexal<\/h2>\n\n\n\n
Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n
Store the ampoules in the outer carton. Sensitive to light.<\/p>\n\n\n\n
Do not use this medicine after the expiry date which is stated on the label or carton after EXP. The expiration date is the last day of the specified month.<\/p>\n\n\n\n
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.<\/p>\n\n\n\n
Contents of the package and other information<\/h2>\n\n\n\nContent declaration<\/h2>\n\n\n\n- The active substance is ondansetron hydrochloride dihydrate equivalent to ondansetron 2 mg \/ ml.<\/li>
- The other ingredients are citric acid monohydrate (E 330), sodium citrate dihydrate (E 331), sodium chloride and water for injections.<\/li><\/ul>\n\n\n\n
What the medicine looks like and contents of the pack<\/h2>\n\n\n\n
Clear solution.<\/p>\n\n\n\n
Glass ampoules; 5 x 2 ml, 25 x 2 ml, 5 x 4 ml, 25 x 4 ml<\/p>\n\n\n\n
Not all pack sizes may be marketed.<\/p>\n\n\n\n
Marketing Authorisation Holder:<\/h2>\n\n\n\n
Hexal A \/ S<\/p>\n\n\n\n
Edvard Thomsens Vej 14<\/p>\n\n\n\n
2300 Copenhagen S<\/p>\n\n\n\n
Denmark<\/p>\n","protected":false},"excerpt":{"rendered":"
Ondansetron Hexal is given prophylactically and as a treatment for nausea and vomiting in connection with chemotherapy, radiation therapy or surgery.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,18526],"tags":[19920,20088,19915,20084,20087,19919,19916,20085,20086,19917],"class_list":["post-19795","post","type-post","status-publish","format-standard","hentry","category-medicines","category-o","tag-benefits-of-ondansetron","tag-benefits-of-ondansetron-hexal","tag-ondansetron","tag-ondansetron-hexal","tag-ondansetron-hexal-side-effects","tag-ondansetron-side-effects","tag-what-is-ondansetron","tag-what-is-ondansetron-hexal","tag-what-ondansetron-hexal-is-used-for","tag-what-ondansetron-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/19795","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=19795"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/19795\/revisions"}],"predecessor-version":[{"id":19848,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/19795\/revisions\/19848"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=19795"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=19795"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=19795"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}