Tramadol<\/a>, a painkiller<\/p>\n\n\n\nAntibiotics such as erythromycin or ketoconazole<\/p>\n\n\n\n
Antiarrhythmic drugs used to treat irregular heartbeat<\/p>\n\n\n\n
Beta-blocking\u00a0drugs are used to treat certain heart or eye problems, anxiety, or to prevent\u00a0migraines.<\/p>\n\n\n\n
– Medicines that affect the heart (eg haloperidol or methadone ),<\/p>\n\n\n\n
SSRIs (Selective Serotonin\u00a0Reuptake\u00a0Inhibitors) are used to treat depression and\/or anxiety.\u00a0This includes medicines containing\u00a0fluoxetine,\u00a0paroxetine,\u00a0sertraline, fluvoxamine,\u00a0citalopram,\u00a0and escitalopram.<\/p>\n\n\n\n
–\u00a0SNRI\u00a0(\u00a0Serotonin\u00a0-noradrenaline reuptake inhibitor) is used to treat depression and\/or anxiety.\u00a0This applies to medicines containing\u00a0venlafaxine, duloxetine,<\/p>\n\n\n\n
– anthracyclines (cancer drugs)<\/p>\n\n\n\n
Some medicines may affect the effect of Ondansetron, or Ondansetron may affect the effectiveness of other medicines.\u00a0This includes:<\/p>\n\n\n\n
apomorphine (a medicine used to treat Parkinson’s disease ): a sharp drop in blood pressure and unconsciousness have been reported with the concomitant use of ondansetron and apomorphine.<\/p>\n\n\n\n
– tramadol (painkiller): Ondansetron reduce the analgesic effect of tramadol.<\/p>\n\n\n\n
–\u00a0phenytoin, carbamazepine (epilepsy medicines), and rifampicin (\u00a0antibiotics\u00a0): these medicines may lower the concentration of ondansetron in the blood.<\/p>\n\n\n\n
Pregnancy and breastfeeding<\/h2>\n\n\n\n You should not use Ondansetron Hameln during the first three months of pregnancy (first trimester).\u00a0The reason is that Ondansetron Hameln may increase the risk slightly that a child is born with cleft lip and\/or\u00a0cleft palate\u00a0(opening or division in the upper lip or palate).\u00a0If you are already pregnant, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking Ondansetron Hameln.\u00a0If you are a woman of\u00a0childbearing potential, you may be advised to use contraception.<\/p>\n\n\n\n
Ondansetron passes into breast milk. Therefore, mothers receiving ondansetron should NOT breast-feed.<\/p>\n\n\n\n
Driving and using machines<\/h2>\n\n\n\n Ondansetron has no or negligible effect on the ability to drive and use machines.<\/p>\n\n\n\n
You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects.\u00a0Descriptions of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n
Ondansetron Hameln contains sodium<\/h2>\n\n\n\n This medicine contains less than 1 mmol (23 mg) sodium per ml, ie essentially ‘sodium-free’.<\/p>\n\n\n\n
How to use Ondansetron Hameln<\/h2>\n\n\n\n Method of administration<\/strong>Dosage Your<\/strong>The dose\u00a0varies depending on your medical treatment (\u00a0chemotherapy\u00a0or surgery), your liver function, and whether it is given as an\u00a0injection\u00a0or\u00a0infusion.<\/p>\n\n\n\n
During chemotherapy or radiation therapy, the usual dose is one for adults 8 – 32 mg ondansetron per day. For the treatment of nausea and vomiting after surgery, a single dose of 4 mg ondansetron is usually given.<\/p>\n\n\n\n
Children and young people<\/strong><\/p>\n\n\n\nChildren older than 6 months and adolescents<\/em>Children older than 1 month and adolescents<\/em>Dose adjustment<\/strong><\/p>\n\n\n\nPatients with hepatic impairment:<\/em>Older<\/em><\/p>\n\n\n\nThere is limited experience with the use of ondansetron for the\u00a0prophylaxis\u00a0and treatment of postoperative nausea and vomiting (PONV) in the elderly.\u00a0However, ondansetron is well tolerated by patients over 65 years of age who are being treated with\u00a0chemotherapy.<\/p>\n\n\n\n
There is limited experience regarding the use of ondansetron as a preventive measure and in the treatment of nausea and vomiting that may occur after surgery (PONV) in the elderly. However, ondansetron is well tolerated by patients over 65 years of age who are being treated with chemotherapy (cancer treatment).<\/p>\n\n\n\n
Patients with renal impairment or who are slow metabolizers<\/em> of sparteine \/ debrisoquine:Duration of treatment<\/strong>Following intravenous administration of Ondansetron Hameln, treatment with other forms of ondansetron can be continued.<\/p>\n\n\n\n
If you use more Ondansetron Hameln than you should <\/h2>\n\n\n\n If you have ingested too much medicine or if e.g.\u00a0If a child has ingested the medicine by mistake, contact a doctor or hospital for risk assessment and advice.<\/p>\n\n\n\n
At present, there is only limited information on overdose with ondansetron.\u00a0In a few patients, the following effects have been observed after overdose: visual disturbances, severe constipation, low\u00a0blood pressure,\u00a0and unconsciousness.\u00a0In all cases, the symptoms disappeared completely.<\/p>\n\n\n\n
There is no specific antidote for ondansetron. For this reason, only the symptoms should be treated in case of suspected overdose.
A doctor or nurse will give you or your child Ondansetron Hameln, so it is unlikely that you or your child will receive too much.\u00a0If you think you or your child have taken too much or missed a\u00a0dose, tell your doctor or nurse.<\/p>\n\n\n\n
If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n
Possible side effects<\/h2>\n\n\n\n Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n
Uncommon (may affect up to 1 in 100 people):<\/em><\/p>\n\n\n\n– Chest pain,\u00a0heart arrhythmias\u00a0(changes in how your heart beats), and\u00a0bradycardia\u00a0(slow heart rate).\u00a0Chest pain and\u00a0heart arrhythmias\u00a0can in some cases be fatal.<\/p>\n\n\n\n
Rare (may affect up to 1 in 1,000 people):<\/em><\/p>\n\n\n\n– Immediate allergic (hypersensitivity) reactions (reaction in which the body reacts with an excessive\u00a0immune response\u00a0to a foreign substance), including life-threatening allergic reactions.\u00a0These reactions can be: swelling of the hands, feet, ankles, face, lips, mouth, or throat which can cause difficulty swallowing and breathing.\u00a0In addition, rash or\u00a0itching\u00a0and\u00a0hives.<\/p>\n\n\n\n
Hypersensitivity reactions were also observed in patients who were sensitive to medical products from the same group.<\/p>\n\n\n\n
Tell your doctor immediately if you experience symptoms that indicate an\u00a0allergic reaction.<\/p>\n\n\n\n
Very common (may affect more than 1 user in 10):<\/em><\/p>\n\n\n\n– Headache.<\/p>\n\n\n\n
Common (may affect up to 1 in 10 people):<\/em><\/p>\n\n\n\nExperience of redness or heat.<\/p>\n\n\n\n
– It is known that ondansetron prolongs the time of passage through the colon and can cause constipation in some patients.<\/p>\n\n\n\n
– Local reactions at the injection site.<\/p>\n\n\n\n
Uncommon (may affect up to 1 in 100 people):<\/em><\/p>\n\n\n\n– Involuntary movement disorders, e.g. jerky eye movements, abnormal muscle contractions that can cause distorted or jerky body movements, seizures (eg epileptic seizures). <\/p>\n\n\n\n
– Hypotension (low blood pressure ). <\/p>\n\n\n\n
– Hiccups.<\/p>\n\n\n\n
Asymptomatic increases in liver function. These reactions were observed mainly in patients receiving chemotherapy with cisplatin.<\/p>\n\n\n\n
Hypersensitivity\u00a0reactions\u00a0around the injection site (eg rash,\u00a0hives,\u00a0itching\u00a0) may occur, which sometimes extend along the vein into which the medicine is injected.<\/p>\n\n\n\n
Rare (may affect up to 1 in 1,000 people):<\/em><\/p>\n\n\n\nTransient changes in the electrocardiogram ( ECG ) (instrumental control of the electronic processes that normally take place when the heart is beating), mainly after intravenous administration of ondansetron. QTc extension (including torsades de pointes ).<\/p>\n\n\n\n
Dizziness with rapid intravenous administration.<\/p>\n\n\n\n
Transient visual disturbances (eg blurred vision) with rapid intravenous administration.<\/p>\n\n\n\n
Very rare (may affect up to 1 in 10,000 people):<\/em><\/p>\n\n\n\n– Depression.<\/p>\n\n\n\n
– In individual cases, transient blindness has been reported in patients receiving\u00a0chemotherapy, including cisplatin.\u00a0Most reported cases went over in 20 minutes.\u00a0Some cases of transient blindness were reported to be of cortical origin (from the cerebral cortex).<\/p>\n\n\n\n
If any of the side effects gets serious, or if you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist.<\/p>\n\n\n\n
How to store Ondansetron Hameln<\/h2>\n\n\n\n Keep out of sight and reach of children.<\/p>\n\n\n\n
Do not use this medicine after the expiry date which is stated on the ampoule label and carton. The expiration date is the last day of the specified month.<\/p>\n\n\n\n
Store the ampoules in the outer carton. Sensitive to light.<\/p>\n\n\n\n
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.<\/p>\n\n\n\n
Contents of the package and other information<\/h2>\n\n\n\nContent declaration<\/h2>\n\n\n\n The active substance is ondansetron.<\/p>\n\n\n\n
Each ampoule of 2 ml contains 4 mg ondansetron.<\/p>\n\n\n\n
Each 4 ml ampoule contains 8 mg ondansetron.<\/p>\n\n\n\n
Each milliliter contains 2 mg of ondansetron as ondansetron hydrochloride dihydrate.<\/p>\n\n\n\n
The other ingredients<\/em>\u00a0are sodium chloride, sodium citrate dihydrate, citric acid monohydrate, and water for injections.<\/p>\n\n\n\nWhat the medicine looks like and contents of the pack<\/h2>\n\n\n\n Ondansetron 2 mg\/ml is a clear and colorless liquid in colorless\u00a0glass ampoules\u00a0containing 2 ml or 4 ml\u00a0solution for injection.<\/p>\n\n\n\n
Pack sizes: 5 and 10 ampoules<\/p>\n\n\n\n
Not all pack sizes may be marketed.<\/p>\n\n\n\n
Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n Marketing Authorization Holder:
Manufacturer:
hameln rds as, Horn\u00e1 36, 900 01 Modra, Slovakia<\/p>\n\n\n\n
HBM Pharma sro, Sklabinsk\u00e1 30, 03680 Martin, Slovakia<\/p>\n\n\n\nDenmark<\/td> Ondansetron Hameln 2 mg \/ ml solution for injection<\/td><\/tr> Finland<\/td> Ondansetron Hameln 2 mg \/ ml injection test, liuos<\/td><\/tr> Netherlands<\/td> Ondansetron hameln 2 mg \/ ml, solution for injection<\/td><\/tr> Norway<\/td> Ondansetron Hameln 2 mg \/ ml solution for injection<\/td><\/tr> UK<\/td> Ondansetron 2 mg \/ ml Solution for Injection<\/td><\/tr> Sweden<\/td> Ondansetron Hameln 2 mg \/ ml solution for injection<\/td><\/tr> Germany<\/td> Ondansetron Entry 2 mg\/ml Solution for injection<\/td><\/tr><\/tbody><\/table><\/figure>\n","protected":false},"excerpt":{"rendered":"Ondansetron Hameln belongs to a group of medicines called antiemetics, medicines for nausea and vomiting. Some treatments with cancer drugs ( chemotherapy ) and radiation therapy can cause nausea or vomiting. You may also feel nauseous and vomit after an operation. Ondansetron Hameln may help reduce these effects.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,18526],"tags":[19920,20093,19915,20089,20092,19919,19916,20090,20091,19917],"class_list":["post-19793","post","type-post","status-publish","format-standard","hentry","category-medicines","category-o","tag-benefits-of-ondansetron","tag-benefits-of-ondansetron-hameln","tag-ondansetron","tag-ondansetron-hameln","tag-ondansetron-hameln-side-effects","tag-ondansetron-side-effects","tag-what-is-ondansetron","tag-what-is-ondansetron-hameln","tag-what-ondansetron-hameln-is-used-for","tag-what-ondansetron-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/19793","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=19793"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/19793\/revisions"}],"predecessor-version":[{"id":19849,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/19793\/revisions\/19849"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=19793"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=19793"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=19793"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}