2 mg \/ ml solution for injection
ondansetron<\/p>\n\n\n\n
Ondansetron Fresenius Kabi belongs to a group of medicines called antiemetics, which are medicines for nausea and vomiting. Some medical treatments with cancer treatment ( chemotherapy ) or radiation therapy may make you nauseous or cause vomiting. Even after surgery, you may feel sick or vomit. Ondansetron Fresenius Kabi can help counteract or stop these symptoms.<\/p>\n\n\n\n
Talk to your doctor, pharmacist, or nurse before using Ondansetron Fresenius Kabi<\/p>\n\n\n\n
Tell your doctor, nurse, or pharmacist if you are taking, have recently taken, or might take any other medicines, including medicines obtained without a prescription.<\/p>\n\n\n\n
If you take tramadol<\/a> (for pain): ondansetron may reduce the analgesic effect of tramadol.<\/p>\n\n\n\n If you take\u00a0phenytoin, carbamazepine (\u00a0antiepileptic drugs\u00a0), or rifampicin (\u00a0antibiotics\u00a0for\u00a0tuberculosis\u00a0): the concentration of ondansetron in your blood may decrease.<\/p>\n\n\n\n If you are taking heart toxic medicines (eg\u00a0anthracyclines, cancer antibiotics such as doxorubicin, daunorubicin, or trastuzumab<\/a>, a cancer medicine),\u00a0antibiotics\u00a0(such as erythromycin), antifungals (such as\u00a0ketoconazole\u00a0),\u00a0antiarrhythmics\u00a0(eg\u00a0amiodarone\u00a0), and\u00a0beta-blockers\u00a0( beta-blockers)\u00a0lower heart rhythm such as atenolol or\u00a0timolol<\/a>\u00a0): use of ondansetron with other\u00a0QT-prolonging drugs may result in further\u00a0QT\u00a0-prolongation, ie increase the risk of\u00a0cardiac arrhythmias.<\/p>\n\n\n\n If you are taking other serotonergic drugs such as selective serotonin reuptake inhibitors (\u00a0SSRIs\u00a0) or\u00a0serotonin\u00a0noradrenaline reuptake inhibitors (\u00a0SNRIs\u00a0) such as\u00a0sertraline\u00a0or duloxetine (both are antidepressants): There are case reports describing patients with the so-called serotonergic syndrome (eg increased alertness and increased alertness). heart rate and\u00a0blood pressure, tremors and hypersensitivity reflexes) after concomitant use of ondansetron with other serotonergic drugs.<\/p>\n\n\n\n If you are taking apomorphine (medicines to treat Parkinson’s disease ): apomorphine should not be used with ondansetron, as there are case reports of severe hypotension (low blood pressure ) and unconsciousness when both medicines are given at the same time.<\/p>\n\n\n\n You should not use Ondansetron during the first three months of pregnancy (first trimester).\u00a0The reason is that Ondansetron may increase the risk slightly that a child is born with cleft lip and\/or\u00a0cleft palate\u00a0(opening or division in the upper lip or palate).\u00a0If you are already pregnant or breast-feeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking Ondansetron.\u00a0If you are a woman of\u00a0childbearing potential, you may be advised to use contraception.<\/p>\n\n\n\n Ondansetron passes into breast milk. Therefore, mothers receiving ondansetron should NOT breast-feed.<\/p>\n\n\n\n Consult your doctor before taking any medication.<\/p>\n\n\n\n Ondansetron does not affect the ability to drive or use machines.<\/p>\n\n\n\n This medicine contains less than 1 mmol (23 mg)\u00a0sodium\u00a0per\u00a0ampoule, ie essentially ‘sodium-free’.<\/p>\n\n\n\n Method of administration<\/strong><\/p>\n\n\n\n Ondansetron Fresenius Kabi is administered as an intravenous injection (into a vein) or, after dilution, as an intravenous infusion (for a long time). It is usually administered by a doctor or nurse.<\/p>\n\n\n\n Dosage<\/strong><\/p>\n\n\n\n Adults (under 75 years of age)<\/em><\/p>\n\n\n\n Your doctor will determine the correct\u00a0dose\u00a0of ondansetron for you.\u00a0Dosage\u00a0one depends on what medical treatment you are receiving (\u00a0chemotherapy\u00a0or\u00a0surgery\u00a0), your liver function, and whether it is given as an\u00a0injection\u00a0or\u00a0infusion.<\/p>\n\n\n\n For chemotherapy or radiation therapy, the usual dose is one for adults 8 – 32 mg ondansetron per day. A single dose of more than 16 mg should not be given. For the treatment of postoperative nausea and vomiting, a single dose of 4 mg ondansetron is usually administered. For the prevention of nausea and vomiting after surgery, a single dose of 4 mg ondansetron is usually administered.<\/p>\n\n\n\n Children aged> 6 months and adolescents<\/em><\/p>\n\n\n\n In\u00a0chemotherapy, the usual\u00a0dose\u00a0is a single\u00a0intravenous\u00a0dose of 5 mg ondansetron per square meter of body surface area immediately before\u00a0chemotherapy.\u00a0The intravenous\u00a0dose\u00a0should not exceed 8 mg.<\/p>\n\n\n\n Children aged> 1 month and adolescents<\/em><\/p>\n\n\n\n For the treatment of nausea and vomiting after surgery, the usual\u00a0dose\u00a0is 0.1 mg\/kg (body weight).\u00a0The maximum\u00a0dose\u00a0is 4 mg as an\u00a0injection\u00a0into a vein.<\/p>\n\n\n\n For the prevention of nausea and vomiting after surgery, the usual\u00a0dose\u00a0is 0.1 mg\/kg (body weight).\u00a0The maximum\u00a0dose\u00a0is 4 mg as an\u00a0injection\u00a0into a vein.\u00a0This will be given shortly before surgery.<\/p>\n\n\n\n Dose adjustment<\/strong><\/p>\n\n\n\n Older:<\/em><\/p>\n\n\n\n During treatment with\u00a0chemotherapy, the initial\u00a0dose\u00a0should not exceed 8 mg for patients aged 75 years and older.<\/p>\n\n\n\n Patients with hepatic impairment:<\/em><\/p>\n\n\n\n If you have liver problems, your doctor will adjust your dose to a maximum daily dose of 8 mg ondansetron.<\/p>\n\n\n\n Patients with renal impairment or slow metabolites of sparteine\/debrisoquine:<\/em><\/p>\n\n\n\n No adjustment of the daily dose, dosing interval, or route of administration is necessary.<\/p>\n\n\n\n Treatment time<\/strong><\/p>\n\n\n\n Your doctor will decide how long you should be treated with ondansetron.<\/p>\n\n\n\n Following intravenous administration of Ondansetron Fresenius Kabi, treatment with ondansetron tablets or suppositories may continue for up to 5 days.<\/p>\n\n\n\n If you have ingested too much medicine or if e.g.\u00a0If a child has ingested the medicine by mistake, contact a doctor or hospital for risk assessment and advice.<\/p>\n\n\n\n There is currently limited information on the effects of an overdose of ondansetron.\u00a0Overdose increases the likelihood of\u00a0side effects\u00a0described in section 4. In a few patients, the following symptoms have been observed after overdose: visual disturbances, severe constipation, low\u00a0blood pressure, disturbed heart rhythm, and unconsciousness.\u00a0In all cases, the symptoms disappeared completely.<\/p>\n\n\n\n Ondansetron will be given to you or your child by a doctor or nurse, so it is unlikely that you or your child will get too much.\u00a0If you think you or your child has taken too much or missed a\u00a0dose, tell your doctor or nurse.<\/p>\n\n\n\n As there is no specific antidote for ondansetron, only the symptoms will be treated in case of suspected overdose.<\/p>\n\n\n\n Tell your doctor if any of these symptoms occur.<\/p>\n\n\n\n Like all medicines, Ondansetron Fresenius Kabi can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n Contact your doctor or nurse immediately if you experience any of the following:<\/strong><\/p>\n\n\n\n Uncommon, <\/em> may affect up to 1 in 100 people<\/em><\/p>\n\n\n\n Rare may affect up to 1 in 1,000 people<\/em><\/p>\n\n\n\n Other side effects may occur<\/strong><\/p>\n\n\n\n Very common, may affect more than 1 user in 10<\/em><\/p>\n\n\n\n Common, <\/em>may affect up to 1 in 10 users<\/em><\/p>\n\n\n\n Uncommon, <\/em> may affect up to 1 in 100 people<\/em><\/p>\n\n\n\n Rare may affect up to 1 in 1,000 people<\/em><\/p>\n\n\n\n Very rare: <\/em> may affect up to 1 in 10,000 people<\/em><\/p>\n\n\n\n Additional side effects are in children and adolescents<\/strong><\/p>\n\n\n\n Side effects in children and adolescents are comparable to those in adults.<\/p>\n\n\n\n Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n This medicine must not be administered after the expiry date which is stated on the ampoule and the carton. The expiration date is the last day of the specified month.<\/p>\n\n\n\n Protect the ampoules from light by storing them in the outer carton.<\/p>\n\n\n\n Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.<\/p>\n\n\n\n The active substance is ondansetron.<\/p>\n\n\n\n Each ampoule of 2 ml contains 4 mg ondansetron.<\/p>\n\n\n\n Each 4 ml ampoule contains 8 mg ondansetron.<\/p>\n\n\n\n Each milliliter contains 2 mg of ondansetron as ondansetron hydrochloride dihydrate.<\/p>\n\n\n\n The other ingredients are sodium chloride, sodium citrate dihydrate, citric acid monohydrate, and water for injections.<\/p>\n\n\n\n Ondansetron Fresenius Kabi is a clear, colorless solution in clear\u00a0glass\u00a0ampoules containing 2 or 4 ml\u00a0solution for injection.<\/p>\n\n\n\n Pack sizes: 1, 5, and 10 ampoules.<\/p>\n\n\n\n Not all pack sizes may be marketed.<\/p>\n\n\n\n Marketing Authorisation Holder:<\/p>\n\n\n\n Fresenius Kabi AB<\/p>\n\n\n\n SE-751 74 Uppsala<\/p>\n\n\n\n Manufacturer:<\/p>\n\n\n\n Labesfal Laboratorios Almiro SA,<\/p>\n\n\n\n Lagedo, 3465-157 Santiago de Besterios,<\/p>\n\n\n\n Portugal<\/p>\n","protected":false},"excerpt":{"rendered":" Ondansetron Fresenius Kabi belongs to a group of medicines called antiemetics, which are medicines for nausea and vomiting. Some medical treatments with cancer treatment ( chemotherapy ) or radiation therapy may make you nauseous or cause vomiting. Even after surgery, you may feel sick or vomit. Ondansetron Fresenius Kabi can help counteract or stop these symptoms.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,18526],"tags":[19920,20098,19915,20094,20097,19919,19916,20095,20096,19917],"class_list":["post-19791","post","type-post","status-publish","format-standard","hentry","category-medicines","category-o","tag-benefits-of-ondansetron","tag-benefits-of-ondansetron-fresenius-kabi","tag-ondansetron","tag-ondansetron-fresenius-kabi","tag-ondansetron-fresenius-kabi-side-effects","tag-ondansetron-side-effects","tag-what-is-ondansetron","tag-what-is-ondansetron-fresenius-kabi","tag-what-ondansetron-fresenius-kabi-is-used-for","tag-what-ondansetron-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/19791","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=19791"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/19791\/revisions"}],"predecessor-version":[{"id":19850,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/19791\/revisions\/19850"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=19791"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=19791"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=19791"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}Pregnancy and breastfeeding<\/h2>\n\n\n\n
Driving and using machines<\/h2>\n\n\n\n
Ondansetron Fresenius Kabi contains sodium<\/h2>\n\n\n\n
How to use Ondansetron Fresenius Kabi<\/h2>\n\n\n\n
If you use more Ondansetron Fresenius Kabi than you should <\/h2>\n\n\n\n
Possible side effects<\/h2>\n\n\n\n
How to store Ondansetron Fresenius Kabi<\/h2>\n\n\n\n
Contents of the package and other information<\/h2>\n\n\n\n
Content declaration<\/h2>\n\n\n\n
What the medicine looks like and contents of the pack<\/h2>\n\n\n\n
Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n