{"id":19551,"date":"2022-03-12T18:04:17","date_gmt":"2022-03-12T18:04:17","guid":{"rendered":"https:\/\/zeepedia.com\/?p=19551"},"modified":"2022-03-14T11:21:54","modified_gmt":"2022-03-14T11:21:54","slug":"olanzapine-accord","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/olanzapine-accord\/","title":{"rendered":"Olanzapine Accord &#8211; Olanzapine uses, dose and side effects"},"content":{"rendered":"\n<p>2.5 mg, 5 mg, 7.5 mg, 10 mg, 15 mg, 20 mg&nbsp;film-coated tablets<br>olanzapine<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Olanzapine Accord is and what it is used for<\/h2>\n\n\n\n<p>Olanzapine Accord contains the active substance olanzapine.&nbsp;Olanzapine Accord belongs to the group of drugs&nbsp;neuroleptics&nbsp;and is used to treat the following conditions:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Schizophrenia, a disease with symptoms such as hearing, seeing or feeling something that does not exist, delusions, unusual suspicion and withdrawal.&nbsp;People with these conditions may also feel depressed, anxious or tense.<\/li><li>Moderate to severe manic episodes, a condition with symptoms such as arousal and&nbsp;euphoria&nbsp;.<\/li><\/ul>\n\n\n\n<p>Olanzapine Accord prevents recurrence of these symptoms in patients with bipolar disorder who have responded to olanzapine treatment in the manic phase.<\/p>\n\n\n\n<p>Olanzapine contained in Olanzapine Accord may also be approved for the treatment of other conditions not mentioned in this product information.\u00a0Ask your doctor, pharmacist, or another healthcare professional if you have any further questions, and always follow their instructions.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before you take Olanzapine Accord<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not take Olanzapine Accord<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic (hypersensitive) to olanzapine or any of the other ingredients of this medicine (listed in section 6).&nbsp;An&nbsp;allergic reaction&nbsp;can manifest itself as a rash,&nbsp;itching&nbsp;, swollen face, swollen lips or shortness of breath.&nbsp;If this happens, consult a doctor.<\/li><li>if you have previously had eye problems such as&nbsp;certain types of&nbsp;glaucoma&nbsp;(increased pressure in the eye).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before taking Olanzapine Accord<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>The use of Olanzapine Accord in elderly patients with dementia is not recommended as it may cause serious&nbsp;side effects&nbsp;.<\/li><li>Drugs of this type can cause unusual movements, mainly in the face or tongue.&nbsp;Contact a doctor if this happens.<\/li><li>This type of medicine can also cause a combination of fever, shortness of breath, sweating, muscle stiffness and drowsiness or drowsiness.&nbsp;These&nbsp;side effects&nbsp;are extremely rare, but if they do occur, contact a doctor immediately.<\/li><li>Weight gain has occurred in patients taking Olanzapine Accord.&nbsp;You and your doctor should check your weight regularly.&nbsp;Consider referral to a dietitian or help with a diet list if necessary.<\/li><li>High blood sugar and high blood fat levels (&nbsp;triglycerides&nbsp;and&nbsp;cholesterol&nbsp;) have been reported in patients taking Olanzapine Accord.&nbsp;Your doctor should do blood tests for blood sugar and fat levels before you start taking Olanzapine Accord and then at regular intervals during treatment.<\/li><li>Tell your doctor if you or anyone in your family has had a blood clot in the past, as medicines like these have been linked to blood clots.<\/li><\/ul>\n\n\n\n<p>Tell your doctor as soon as possible if you have or have had:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Stroke&nbsp;or mild form of&nbsp;stroke&nbsp;(temporary symptoms of&nbsp;stroke&nbsp;)<\/li><li>Parkinson&#8217;s disease<\/li><li>Prostate problem<\/li><li>Intestinal upset (paralytic&nbsp;ileus&nbsp;)<\/li><li>Liver or kidney disease<\/li><li>Blood disease<\/li><li>Heart disease<\/li><li>Diabetes<\/li><li>Seizures<\/li><li>If you know you may have a salt deficiency due to prolonged severe diarrhea and vomiting or use&nbsp;diuretics&nbsp;(&nbsp;diuretics&nbsp;).<\/li><\/ul>\n\n\n\n<p>If you have dementia, you or your caregiver\/relative should inform your doctor if you have ever had a\u00a0stroke\u00a0or mild form of\u00a0stroke.<\/p>\n\n\n\n<p>If you are over 65, your&nbsp;blood pressure&nbsp;should be checked regularly by your doctor.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children and young people<\/h2>\n\n\n\n<p>Olanzapine Accord is not for use in patients under 18 years of age.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Olanzapine Accord<\/h2>\n\n\n\n<p>Only take other medicines during Olanzapine Accord treatment if your doctor advises you to do so.\u00a0Along with the following medicines, drowsiness may occur medicines for depression and anxiety and sleeping pills (sedatives).<\/p>\n\n\n\n<p>Tell your doctor if you are taking, have recently taken, or might take any other medicines.<\/p>\n\n\n\n<p>You must tell your doctor if you are taking:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>medicines for&nbsp;Parkinson&#8217;s disease<\/li><li>carbamazepine (for&nbsp;epilepsy&nbsp;and mood stabilizers), fluvoxamine (for depression) or&nbsp;ciprofloxacin&nbsp;(&nbsp;antibiotics&nbsp;) &#8211; it may be necessary to adjust your Olanzapine Accord&nbsp;dose&nbsp;.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Olanzapine Accord with alcohol<\/h2>\n\n\n\n<p>Do not drink alcohol during treatment with Olanzapine Accord as it may cause drowsiness with alcohol.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.\u00a0You should not take this medicine if you are breastfeeding as small amounts of olanzapine may pass into breast milk.<\/p>\n\n\n\n<p>The following symptoms may occur in newborns of mothers who have used olanzapine during the last trimester (last three months of pregnancy): tremors, muscle stiffness and\/or weakness, drowsiness, anxiety, difficulty breathing, and difficulty eating.\u00a0If your child has any of these symptoms, you may need to consult a doctor.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>There is a risk that you may feel drowsy when using Olanzapine Accord.&nbsp;If this happens, do not drive or use any tools or machines and consult your doctor.<\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects.\u00a0Descriptions of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Olanzapine Accord contains lactose<\/h2>\n\n\n\n<p>If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to take Olanzapine Accord<\/h2>\n\n\n\n<p>Always take this medicine exactly as your doctor has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p>Dose&nbsp;one and the duration of treatment is determined by your doctor.&nbsp;Dose&nbsp;one of Olanzapine Accord is 5\u221220 mg per day.&nbsp;Contact your doctor if symptoms return but do not stop taking Olanzapine Accord unless your doctor tells you to.<\/p>\n\n\n\n<p>You should take Olanzapine Accord once a day according to your doctor&#8217;s instructions.&nbsp;Try to take the tablets at the same time each day.&nbsp;It does not matter if you take them with or without food.&nbsp;Film-coated Olanzapine Accord tablets should be taken by mouth and swallowed whole with water.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you take more Olanzapine Accord than you should<\/h2>\n\n\n\n<p>If you have ingested too much medicine or if e.g.\u00a0a child ingested the medicine by mistake, contact a doctor or hospital for risk assessment and advice.<\/p>\n\n\n\n<p>Patients who have taken too much Olanzapine Accord have the following symptoms: rapid heart rate, agitation\/aggression, difficulty speaking, involuntary movements (especially of the face or tongue), and decreased consciousness.\u00a0Other symptoms may include\u00a0acute\u00a0confusion, seizures (\u00a0epilepsy\u00a0),\u00a0coma, a combination of fever, shortness of breath, sweating, muscle stiffness, drowsiness or drowsiness, slow breathing, difficulty breathing, high or low\u00a0blood pressure, abnormal heart rhythm.\u00a0Contact a doctor or hospital immediately if you experience any of the listed symptoms.\u00a0Show your doctor your tablet pack.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to take Olanzapine Accord<\/h2>\n\n\n\n<p>Take your tablets as soon as you remember.&nbsp;Do not take two&nbsp;doses&nbsp;on the same day.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop taking Olanzapine Accord<\/h2>\n\n\n\n<p>Do not stop taking Olanzapine Accord just to make you feel better.\u00a0You must continue to take Olanzapine Accord for as long as your doctor prescribes it.<\/p>\n\n\n\n<p>If you suddenly stop taking Olanzapine Accord, you may experience symptoms such as sweating, difficulty sleeping, tremors, anxiety, nausea, and vomiting.\u00a0Your doctor may recommend that you reduce the\u00a0dose\u00a0gradually before stopping treatment.<\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p>Contact your doctor immediately if you get:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>involuntary movement disorders (a common side effect that can affect up to 1 in 10 users) especially in the face or tongue<\/li><li>blood clots in the veins (a less common&nbsp;side effect&nbsp;that can affect up to 1 in 100 people) especially in the legs (symptoms are swelling, pain and&nbsp;redness&nbsp;on the legs).&nbsp;The blood clots can be transported to the lungs and cause chest pain and difficulty breathing.&nbsp;If you experience any of these symptoms, seek medical attention immediately.<\/li><li>a combination of fever, faster breathing, sweating, muscle stiffness and drowsiness or drowsiness (the frequency of this&nbsp;side effect&nbsp;can not be calculated from the available data).<\/li><\/ul>\n\n\n\n<p>Very common&nbsp;side effects&nbsp;(may affect more than 1 in 10 people) include weight gain;&nbsp;drowsiness and increased levels of&nbsp;prolactin&nbsp;in the blood.&nbsp;At the beginning of treatment, some people may feel dizzy or faint (with a slow heart rate), especially when getting up from a lying or sitting position.&nbsp;This often disappears by itself.&nbsp;If not, contact your doctor.<\/p>\n\n\n\n<p>Common\u00a0side effects\u00a0(may affect up to 1 in 10 people) include changes in levels of\u00a0blood cells, blood fats and at the beginning of treatment, temporary increase in liver enzymes;\u00a0increased blood sugar and urine levels;\u00a0elevated levels of\u00a0uric acid\u00a0and\u00a0creatinine\u00a0phosphokinase in the blood;\u00a0increased appetite;\u00a0dizziness;\u00a0restlessness;\u00a0tremors;\u00a0movement difficulties (\u00a0dyskinesia\u00a0);\u00a0constipation;\u00a0dry mouth;\u00a0rash;\u00a0impotence;\u00a0extreme fatigue;\u00a0fluid retention leading to swelling of the hands, ankles or feet;\u00a0fever, joint pain and sexual problems such as decreased sex drive in men and women or erection problems in men.<\/p>\n\n\n\n<p>Uncommon\u00a0side effects\u00a0(may affect up to 1 in 100 people) include hypersensitivity (eg swelling of the mouth and throat,\u00a0itching, rash);\u00a0diabetes\u00a0or exacerbation of diabetes, sometimes associated with\u00a0ketoacidosis\u00a0(ketones in the blood and urine) or coma;\u00a0seizures, generally with known susceptibility to seizures (\u00a0epilepsy\u00a0);\u00a0muscle stiffness or\u00a0spasm (including eye movements);\u00a0ant crawls and feeling of restlessness in the legs at rest (restless legs);\u00a0speech difficulties;\u00a0stuttering;\u00a0slow heartbeat;\u00a0sun sensitivity;\u00a0nosebleed;\u00a0stretched abdomen;\u00a0dragline;\u00a0memory loss or forgetfulness;\u00a0urinary incontinence;\u00a0difficulty urinating;\u00a0hair loss;\u00a0missed or shortened menstruation;\u00a0and breast changes in men and women such as abnormal production of breast milk or abnormal enlargement.<\/p>\n\n\n\n<p>Rare\u00a0side effects\u00a0(may affect up to 1 in 1,000 people) include lowering of normal body temperature;\u00a0abnormal heart rhythm;\u00a0sudden, unexplained death;\u00a0inflammation\u00a0of the pancreas that caused severe stomach pain, fever and malaise;\u00a0liver disease manifested in yellowing of the skin and whites of the eyes;\u00a0muscle disease manifested in unexplained aches and pains;\u00a0and prolonged and\/or painful\u00a0erection.<\/p>\n\n\n\n<p>Very rare\u00a0side effects\u00a0include severe allergic reactions such as drug reactions with\u00a0eosinophilia\u00a0and systemic symptoms (DRESS).\u00a0DRESS initially appears with\u00a0flu-like symptoms\u00a0with rash on the face and then by more widespread rash, fever, enlarged\u00a0lymph nodes, elevated levels of liver enzymes seen in blood tests, and elevated levels of a type of\u00a0white blood cell\u00a0(\u00a0eosinophils\u00a0).<\/p>\n\n\n\n<p>During treatment with olanzapine, elderly patients with dementia may experience\u00a0a stroke,\u00a0pneumonia, urinary incontinence, increased tendency to fall, extreme fatigue, visual hallucinations, elevated body temperature, reddening of the skin, and difficulty walking.\u00a0Some deaths have been reported in this specific patient group.<\/p>\n\n\n\n<p>For patients with\u00a0Parkinson&#8217;s disease, Olanzapine Accord may worsen the symptoms.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Olanzapine Accord<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Keep this medicine out of the sight and reach of children.<\/li><li>Do not use this medicine after the expiry date which is stated on the blister and carton after \u201cEXP\u201d.&nbsp;The expiration date is the last day of the specified month.<\/li><li>Do not store above 30 \u00b0 C.<\/li><li>The medicine should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the package and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<p>The active substance is olanzapine.<\/p>\n\n\n\n<p>Each film-coated tablet contains either 2.5 mg, 5 mg, 7.5 mg, 10 mg, 15 mg or 20 mg of active substance.<\/p>\n\n\n\n<p>The other ingredients are\u00a0lactose monohydrate, microcrystalline cellulose, crospovidone, hydroxypropyl cellulose, and magnesium stearate.<\/p>\n\n\n\n<p>The film coating contains hypromellose (E464), titanium dioxide (E171), macrogol 400, polysorbate 80 (E433).\u00a0The file coating on 15 mg tablets also contains indigo carmine aluminum lacquer (E132) and the 20 mg tablets red iron oxide (E172)<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and contents of the pack<\/h2>\n\n\n\n<p>Olanzapine Accord 2.5 mg: white to off-white, round, biconvex, film-coated tablets, smooth on both sides<\/p>\n\n\n\n<p>Olanzapine Accord 5 mg: white to off-white, round, biconvex, film-coated tablets, debossed with \u201cO1\u201d on one side and smooth on the other side.<\/p>\n\n\n\n<p>Olanzapine Accord 7.5 mg: white to off-white, round, biconvex, film-coated tablets, debossed with \u201cO2\u201d on one side and smooth on the other.<\/p>\n\n\n\n<p>Olanzapine Accord 10 mg: white to off-white, round, biconvex, film-coated tablets, debossed with \u201cO3\u201d on one side and smooth on the other side.<\/p>\n\n\n\n<p>Olanzapine Accord 15 mg tablets: light blue, round, biconvex, film-coated tablets, smooth on both sides<\/p>\n\n\n\n<p>Olanzapine Accord 20 mg tablets: light pink, round, biconvex, film-coated tablets, smooth on both sides<\/p>\n\n\n\n<p>The tablets are available in packs of 15, 28, 30, 35, 56, or 70 tablets for strengths of 2.5 mg, 5 mg, 10 mg and 15 mg.<\/p>\n\n\n\n<p>The tablets are available in packs of 28, 30, 35, 56, or 70 tablets for the strengths of 7.5 mg and 20 mg.<\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p><strong>Marketing Authorisation Holder<\/strong><\/p>\n\n\n\n<p>Accord Healthcare BV<\/p>\n\n\n\n<p>Winthontlaan 200<\/p>\n\n\n\n<p>3526 kV Utrecht<\/p>\n\n\n\n<p>Netherlands<\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>Accord Healthcare BV<\/p>\n\n\n\n<p>Winthontlaan 200<\/p>\n\n\n\n<p>3526 kV Utrecht<\/p>\n\n\n\n<p>Netherlands&nbsp;<\/p>\n\n\n\n<p>Accord Healthcare Limited, Sage House, 319, Pinner Road, North Harrow, Middlesex, HA1 4HF, UK<\/p>\n\n\n\n<p>Accord Healthcare Polska Sp.z oo, ul.&nbsp;Lutomierska 50,95-200 Pabianice, Poland<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Olanzapine Accord contains the active substance olanzapine. Olanzapine Accord belongs to the group of drugs neuroleptics and is used to treat the following conditions:<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,18526],"tags":[19678,19708,10033,19703,19707,19706,19677,19676,10034,19704,19705,10035],"class_list":["post-19551","post","type-post","status-publish","format-standard","hentry","category-medicines","category-o","tag-benefits-of-olanzapine","tag-benefits-of-olanzapine-accord","tag-olanzapine","tag-olanzapine-accord","tag-olanzapine-accord-side-effects","tag-olanzapine-accord-tablet","tag-olanzapine-side-effects","tag-olanzapine-tablet","tag-what-is-olanzapine","tag-what-is-olanzapine-accord","tag-what-olanzapine-accord-is-used-for","tag-what-olanzapine-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/19551","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=19551"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/19551\/revisions"}],"predecessor-version":[{"id":19589,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/19551\/revisions\/19589"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=19551"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=19551"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=19551"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}