Men<\/em><\/p>\n\n\n\nWhile taking Odomzo, always use a condom (with a spermicide, if available) during sexual intercourse with a female partner, even if you have undergone vasectomy. You must continue to do this for 6 months after the end of treatment.<\/p>\n\n\n\n
Tell your doctor immediately if your partner becomes pregnant while you are taking Odomzo and for 6 months after your treatment has ended.<\/p>\n\n\n\n
You should not donate semen during treatment or within 6 months after the end of treatment.<\/p>\n\n\n\n
Driving and using machines<\/h2>\n\n\n\n
Odomzo is unlikely to affect your ability to drive or use tools or machines. Talk to your doctor if you are unsure.<\/p>\n\n\n\n
Odomzo contains lactose<\/h2>\n\n\n\n
Odomzo contains lactose (milk sugar). If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.<\/p>\n\n\n\n
How to take Odomzo<\/h2>\n\n\n\n
Always take this medicine exactly as your doctor or pharmacist has told you. Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n
How to take this medicine<\/strong><\/p>\n\n\n\nThe recommended dose is 200 mg (1 capsule) per day.<\/p>\n\n\n\n
- Do not eat for 2 hours before taking Odomzo and 1 hour afterwards.<\/li>
- Take your capsule at about the same time each day. This will make it easier to remember when to take your medicine.<\/li>
- The capsule should be swallowed whole. It must not be opened, chewed or crushed. All contact with the contents of the capsules should be avoided, as it can have harmful effects.<\/li><\/ul>\n\n\n\n
Do not change the\u00a0dose\u00a0without talking to your doctor.\u00a0Do not take more medicines than your doctor prescribed.\u00a0If you vomit after swallowing the capsule, do not take any more capsules until the next scheduled\u00a0dose.<\/p>\n\n\n\n
How long should you take Odomzo?<\/strong><\/p>\n\n\n\nContinue to take Odomzo for as long as your doctor prescribes it. Talk to your doctor or pharmacist if you are wondering how long to take Odomzo.<\/p>\n\n\n\n
If you take more Odomzo than you should<\/h2>\n\n\n\n
If you have taken too much Odomzo, or if someone else has accidentally taken your medicine, contact a doctor or go to the hospital immediately. Bring the medicine with the package and package leaflet.<\/p>\n\n\n\n
If you forget to take Odomzo<\/h2>\n\n\n\n
If you forget to take a\u00a0dose\u00a0of Odomzo, take it as soon as you realize it.\u00a0If more than six hours have passed since 34\u00a0dose\u00a0one should have been taken, skip the missed\u00a0dose\u00a0one and then take the next\u00a0dose\u00a0at the appointed time.\u00a0Do not take a double\u00a0dose\u00a0to make up for a forgotten\u00a0dose.<\/p>\n\n\n\n
If you stop taking Odomzo<\/h2>\n\n\n\n
Do not stop taking Odomzo without talking to your doctor first.<\/p>\n\n\n\n
If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n
Possible side effects<\/h2>\n\n\n\n
Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n
Odomzo can cause severe birth defects. You must not become pregnant while taking this medicine (see “Pregnancy, breast-feeding and fertility” and “Contraceptive measures for women and men” in section 2 for further information).<\/p>\n\n\n\n
Stop taking Odomzo and tell your doctor immediately if you notice any of the following, as it may be a sign of an allergic reaction:<\/p>\n\n\n\n
- difficulty breathing or swallowing<\/li>
- swelling of the face, lips, tongue or throat<\/li>
- severely itchy skin with red rashes or lumps.<\/li><\/ul>\n\n\n\n
Some side effects can be serious<\/strong><\/p>\n\n\n\nIf you notice any of the following, tell your doctor or pharmacist immediately:<\/p>\n\n\n\n
- Severe muscle cramps, muscle pain or muscle weakness. This can be a sign of a complication called rhabdomyolysis , which involves breaking down muscle tissue.<\/li>
- Dark-colored urine, small amounts of urine or no urine at all. This can be a sign that the muscle fibers are being broken down, which is damaging the kidneys.<\/li><\/ul>\n\n\n\n
Other possible side effects<\/strong><\/p>\n\n\n\nIf any of these side effects gets worse, talk to your doctor or pharmacist.<\/p>\n\n\n\n
Very common:<\/strong> may affect more than 1 in 10 people<\/p>\n\n\n\n- muscle cramps, muscle aches, pain in the skeleton, ligaments and tendons<\/li>
- no menstruation<\/li>
- diarrhea or heartburn<\/li>
- reduced appetite<\/li>
- headache<\/li>
- altered taste experience or strange taste in the mouth<\/li>
- abdominal pain<\/li>
- feeling sick<\/li>
- vomiting<\/li>
- itching<\/li>
- hair loss<\/li>
- fatigue<\/li>
- pains<\/li>
- weight loss.<\/li><\/ul>\n\n\n\n
Common<\/strong> can occur in up to 1 in 10 people<\/p>\n\n\n\n- upset stomach or indigestion<\/li>
- constipation<\/li>
- rash<\/li>
- abnormal hair growth<\/li>
- thirst, small amounts of urine, weight loss, dry and reddened skin, irritability (possible symptoms of low fluid levels in the body, ie dehydration, also called dehydration ).<\/li><\/ul>\n\n\n\n
During treatment with Odomzo you may also get some<\/strong>\u00a0abnormal blood counts.\u00a0These can alert your doctor about possible changes in the function of various parts of your body, for example:<\/strong><\/p>\n\n\n\n- high levels of the following enzymes: creatine phosphokinase (muscle function), lipase and \/ or amylase (pancreatic function), alanine aminotransferase ( ALT ) and \/ or aspartate aminotransferase ( ASAT ) (liver function)<\/li>
- high creatinine value (renal function)<\/li>
- high blood sugar ( hyperglycaemia )<\/li>
- low hemoglobin value ( hemoglobin is needed to transport oxygen in the blood)<\/li>
- low white blood cell count .<\/li><\/ul>\n\n\n\n
How to store Odomzo<\/h2>\n\n\n\n- Keep this medicine out of the sight and reach of children.<\/li>
- Do not use this medicine after the expiry date which is stated on the carton and blister after EXP. The expiration date is the last day of the specified month.<\/li>
- Do not store above 30 \u00b0 C.<\/li>
- Store in the original package. Moisture sensitive.<\/li>
- Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.<\/li><\/ul>\n\n\n\n
Contents of the pack and other information<\/h2>\n\n\n\nContent declaration<\/h2>\n\n\n\n- The active substance is sonidegib (as phosphate ). Each capsule contains 200 mg of sonidegib.<\/li>
- Other ingredients are:<\/li>
- Capsule contents: crospovidone type A, lactose monohydrate (see section 2, ‘Odomzo contains lactose’), magnesium stearate, poloxamer (188), colloidal anhydrous silica, sodium lauryl sulphate.
- Capsule shell: gelatin, red iron oxide (E172), titanium dioxide (E171).<\/li>
- Ink: black iron oxide (E172), propylene glycol (E1520), shellac.<\/li><\/ul><\/li><\/ul>\n\n\n\n
What the medicine looks like and contents of the pack<\/h2>\n\n\n\n
Odomzo 200 mg capsules are pink and opaque, imprinted with \u201cSONIDEGIB 200MG\u201d and \u201cNVR\u201d.<\/p>\n\n\n\n
Odomzo is packaged in perforated unit dose blisters containing 10 x 1 capsules. It is available in packs of 10 or 30 capsules.<\/p>\n\n\n\n
Not all pack sizes may be marketed.<\/p>\n\n\n\n
Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n
Sun Pharmaceutical Industries Europe BV<\/p>\n\n\n\n
Polarisavenue 87<\/p>\n\n\n\n
2132JH Hoofddorp<\/p>\n\n\n\n
Netherlands<\/p>\n\n\n\n
Contact the representative of the marketing authorization holder to find out more about this medicine:<\/p>\n\n\n\n
Sun Pharmaceutical Industries Europe BV<\/p>\n\n\n\n
Tel: +31 23 568 55 0<\/p>\n","protected":false},"excerpt":{"rendered":"
Odomzo contains the active substance sonidegib. It is a medicine for cancer.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,18526],"tags":[19596,19591,19592,19595,19587,19590,19593,19588,19594,19589],"class_list":["post-19490","post","type-post","status-publish","format-standard","hentry","category-medicines","category-o","tag-benefits-of-odomzo","tag-benefits-of-sonidegib","tag-odomzo","tag-odomzo-side-effects","tag-sonidegib","tag-sonidegib-side-effects","tag-what-is-odomzo","tag-what-is-sonidegib","tag-what-odomzo-is-used-for","tag-what-sonidegib-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/19490","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=19490"}],"version-history":[{"count":5,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/19490\/revisions"}],"predecessor-version":[{"id":19521,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/19490\/revisions\/19521"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=19490"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=19490"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=19490"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}