300 mg enteropowder and oral suspension
posaconazole<\/p>\n\n\n\n
Noxafil contains a drug called posaconazole. It belongs to a group of medicines called “antifungal medicines”. It is used to prevent or treat many different fungal infections.<\/p>\n\n\n\n
This medicine works by killing or stopping the growth of certain types of fungi that can cause\u00a0infection.<\/p>\n\n\n\n
Noxafil can be used in children from 2 years of age to treat the following types of fungal infections when other antifungal medicines have not worked or you have stopped taking them:<\/p>\n\n\n\n
This medicine can also be used to prevent fungal infections in children from 2 years of age who are at high risk of getting a fungal infection such as:<\/p>\n\n\n\n
Do not take Noxafil if any of the above apply to you or your child. If you are not sure, talk to your doctor or pharmacist before taking Noxafil.<\/p>\n\n\n\n
See the section \u201cOther medicines and Noxafil\u201d below for more information including information about other medicines that may affect Noxafil.<\/p>\n\n\n\n
Talk to your doctor, pharmacist, or nurse before taking Noxafil if you or your child:<\/p>\n\n\n\n
If any of the above applies to you or your child (or you are not sure) talk to your doctor, pharmacist, or nurse before taking Noxafil.<\/p>\n\n\n\n
If you develop severe diarrhea or vomiting (feeling unwell) while taking Noxafil, talk to a doctor, pharmacist, or nurse immediately as this may prevent it from working properly.\u00a0See section 4 for more information.<\/p>\n\n\n\n
Noxafil should not be given to children under 2 years of age.<\/p>\n\n\n\n
Tell your doctor or pharmacist if you or your child are taking, have recently taken, or might take any other medicines.<\/p>\n\n\n\n
Do not take Noxafil if you or your child take any of the following:<\/strong><\/p>\n\n\n\n Noxafil can increase the amount of these medicines in the blood, which can cause very serious disorders of your heart rhythm.<\/p>\n\n\n\n Do not take Noxafil if any of the above apply to you or your child. If you are not sure, talk to your doctor or pharmacist before taking this medicine.<\/p>\n\n\n\n Other drugs<\/p>\n\n\n\n See the list above of medicines that must not be used while you or your child are taking Noxafil.\u00a0In addition to the drugs mentioned above, other drugs carry a risk of arrhythmias that can be greater when taken with Noxafil.\u00a0Tell your doctor about any medicines you or your child are taking (prescription or over-the-counter).<\/p>\n\n\n\n Some medicines may increase the risk of side effects from Noxafil by increasing the amount of Noxafil in your blood.<\/p>\n\n\n\n The following medicines may reduce the effect of Noxafil by reducing the amount of Noxafil in your blood:<\/p>\n\n\n\n Noxafil may increase the risk of\u00a0side effects\u00a0from certain other medicines by increasing the amount of these medicines in your blood.\u00a0These medicines include:<\/p>\n\n\n\n If any of the above applies to you or your child (or you are not sure) talk to your doctor or pharmacist before taking Noxafil.<\/p>\n\n\n\n Tell your doctor if you are pregnant or think you may be pregnant before using Noxafil. Do not take Noxafil during pregnancy unless your doctor tells you to.<\/p>\n\n\n\n You should use effective contraception while taking this medicine if you are a woman and could become pregnant. Contact your doctor immediately if you become pregnant during treatment with Noxafil.<\/p>\n\n\n\n Do not breastfeed while you are being treated with Noxafil as small amounts may pass into breast milk.<\/p>\n\n\n\n You may feel dizzy, drowsy, or have blurred vision when taking Noxafil, which may affect your ability to drive or use machines.\u00a0If this happens, do not drive or use machines and consult your doctor.<\/p>\n\n\n\n Noxafil contains methyl parahydroxybenzoate and propyl parahydroxybenzoate<\/strong><\/p>\n\n\n\n This medicine contains methyl parahydroxybenzoate (E218) and propyl parahydroxybenzoate. May cause an allergic reaction (possibly delayed).<\/p>\n\n\n\n Noxafil contains sorbitol<\/strong><\/p>\n\n\n\n This medicine contains 47 mg sorbitol (E420) per milliliter.<\/p>\n\n\n\n Sorbitol is a source of fructose.\u00a0If you (or your child) have hereditary\u00a0fructose intolerance, a rare inherited disease, talk to a doctor before you (or your child) take or receive this medicine.<\/p>\n\n\n\n Noxafil contains propylene glycol<\/strong><\/p>\n\n\n\n This medicine contains 7 mg of propylene glycol (E1520) per milliliter.<\/p>\n\n\n\n Noxafil contains sodium<\/strong><\/p>\n\n\n\n This medicine contains less than 1 mmol (23 mg)\u00a0sodium\u00a0per\u00a0dose, ie essentially ‘sodium-free’.\u00a0is next to “sodium-free”.<\/p>\n\n\n\n Do not switch between Noxafil enteropowder and liquid for\u00a0oral\u00a0suspension\u00a0and Noxafil\u00a0oral\u00a0suspension.<\/p>\n\n\n\n Always give this medicine to children according to the doctor’s or pharmacist’s instructions. If you are not sure, talk to your child’s doctor or pharmacist.<\/p>\n\n\n\n Noxafil enteric powder and liquid for oral suspension with food and drink<\/strong><\/p>\n\n\n\n This medicine can be taken with or without food.<\/p>\n\n\n\n Dosage<\/strong><\/p>\n\n\n\n The recommended\u00a0dose\u00a0for children from 2 years up to 18 years, weighing 10-40 kg is shown in the table below.<\/p>\n\n\n\n On day 1, the recommended dose is given twice.<\/p>\n\n\n\n After day 1, the recommended dose is given once daily.<\/p>\n\n\n\n For children weighing more than 40 kg, Noxafil tablets are recommended if they can swallow whole tablets.<\/p>\n\n\n\n The duration of treatment may depend on the type of\u00a0infection\u00a0you or your child has or how long the immune system is not working properly and may be individually tailored by your doctor.\u00a0Do not change the\u00a0dose\u00a0or treatment schedule yourself until you have consulted your doctor.<\/p>\n\n\n\n If you think you or your child may have used too much Noxafil, talk to a doctor or go to the hospital immediately.<\/p>\n\n\n\n If you have any further questions on the use of this product, ask your doctor, pharmacist, or nurse.<\/p>\n\n\n\n Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n Serious side effects are<\/strong><\/p>\n\n\n\n Talk to a doctor, pharmacist, or nurse immediately if you experience any of the following serious\u00a0side effects\u00a0– you or your child may need immediate medical attention:<\/strong><\/p>\n\n\n\n Other side effects are<\/strong><\/p>\n\n\n\n Tell your doctor, pharmacist, or nurse if you experience any of the following side effects:<\/p>\n\n\n\n Common (may affect up to 1 in 10 people)<\/p>\n\n\n\n Uncommon (may affect up to 1 in 100 people)<\/p>\n\n\n\n Rare (may affect up to 1 in 1,000 people)<\/p>\n\n\n\n No known frequency (can not be calculated from the available data)<\/p>\n\n\n\n Talk to your doctor, pharmacist, or nurse if you get any of the\u00a0side effects\u00a0listed above.<\/p>\n\n\n\n Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n Do not use this medicine after the expiry date which is stated on the carton after EXP. The expiration date is the last day of the specified month.<\/p>\n\n\n\n This medicine does not require any special storage instructions.<\/p>\n\n\n\n Medicines or diluents should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.<\/p>\n\n\n\n Read the instructions in the instructions for use for the correct handling of leftover medicine.<\/p>\n\n\n\n The active substance is posaconazole.\u00a0Each\u00a0single-use sachet of oral powder for\u00a0oral\u00a0suspension\u00a0is a white to a yellow powder containing 300 mg posaconazole.<\/p>\n\n\n\n The other ingredients are hypromellose acetate succinate.<\/p>\n\n\n\n The diluent contains the following: purified water,\u00a0glycerol\u00a0(E422), methyl parahydroxybenzoate (E218), propyl parahydroxybenzoate, sodium dihydrogen phosphate monohydrate, citric acid, anhydrous (E330), xanthan gum (E415), sodium citrate (E415) sodium cirrose E407), sorbitol solution (E420), potassium sorbate (E202), flavoring, sweet berries and citrus (containing propylene glycol (E1520), water, natural and artificial flavors),\u00a0antifoam Af\u00a0emulsion (containing polyethylene glycol (\u00a0E1521\u00a0), octamethylcyclopanethecanyloxane and poly (oxy-1,2-ethanediol), alpha- (1-oxooctadecyl)-omega.-hydroxy).<\/p>\n\n\n\n Noxafil enteric powder and liquid for oral suspension are supplied as a pack of:<\/p>\n\n\n\n Package 1: The pack contains 8 childproof disposable sachets (PET\/aluminum \/ LLDPE), two 3 ml syringes (green) with slotted tips, two 10 ml syringes (blue) with slotted tips, two mixing cups, 473 ml\u00a0diluent\u00a0in a bottle ( HDPE) with polypropylene (PP) closure with foil closure and a bottle adapter for the diluent bottle.<\/p>\n\n\n\n Package 2: A carton of six 3 ml syringes (green) with slotted tips and six 10 ml syringes (blue) with slotted tips.<\/p>\n\n\n\n Each\u00a0single-use sachet contains 300 mg posaconazole, which is mixed in 9 ml of\u00a0diluent\u00a0to obtain a total of 10 ml of\u00a0suspension\u00a0with a final concentration of approximately 30 mg per ml.<\/p>\n\n\n\n Marketing Authorisation Holder<\/p>\n\n\n\n Merck Sharp & Dohme BV<\/p>\n\n\n\n Waarderweg 39<\/p>\n\n\n\n 2031 BN Haarlem<\/p>\n\n\n\n Netherlands<\/p>\n\n\n\n Manufacturer<\/p>\n\n\n\n NV Organon<\/p>\n\n\n\n Kloosterstraat 6<\/p>\n\n\n\n 5349 AB Oss<\/p>\n\n\n\n Netherlands<\/p>\n\n\n\n Contact the representative of the marketing authorization holder to find out more about this medicine:<\/p>\n\n\n\n Noxafil contains a drug called posaconazole. It belongs to a group of medicines called “antifungal medicines”. It is used to prevent or treat many different fungal infections.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,15581],"tags":[19375,19370,19371,19374,19366,19369,19372,19367,19373,19368],"class_list":["post-19289","post","type-post","status-publish","format-standard","hentry","category-medicines","category-n","tag-benefits-of-noxafil","tag-benefits-of-posaconazole","tag-noxafil","tag-noxafil-side-effects","tag-posaconazole","tag-posaconazole-side-effects","tag-what-is-noxafil","tag-what-is-posaconazole","tag-what-noxafil-is-used-for","tag-what-posaconazole-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/19289","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=19289"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/19289\/revisions"}],"predecessor-version":[{"id":19342,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/19289\/revisions\/19342"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=19289"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=19289"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=19289"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}Pregnancy and breastfeeding<\/h2>\n\n\n\n
Driving and using machines<\/h2>\n\n\n\n
Noxafil contains<\/h2>\n\n\n\n
How to take Noxafil<\/h2>\n\n\n\n
Body weight (kg)<\/strong><\/td> Dose (volume)<\/strong><\/td><\/tr> 10- <12 kg<\/td> 90 mg (3 ml)<\/td><\/tr> 12- <17 kg<\/td> 120 mg (4 ml)<\/td><\/tr> 17- <21 kg<\/td> 150 mg (5 ml)<\/td><\/tr> 21- <26 kg<\/td> 180 mg (6 ml)<\/td><\/tr> 26- <36 kg<\/td> 210 mg (7 ml)<\/td><\/tr> 36-40 kg<\/td> 240 mg (8 ml)<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n If you or your child have taken too much Noxafil<\/h2>\n\n\n\n
If you forget to take Noxafil<\/h2>\n\n\n\n
Possible side effects<\/h2>\n\n\n\n
How to store Noxafil<\/h2>\n\n\n\n
Contents of the package and other information<\/h2>\n\n\n\n
Content declaration<\/h2>\n\n\n\n
What the medicine looks like and contents of the pack<\/h2>\n\n\n\n
Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n
Belgium \/ Belgique \/ Belgien<\/strong>MSD BelgiumTel: +32 (0) 2 776 62 11dpoc_belux@merck.com<\/td> Lithuania<\/strong>UAB Merck Sharp & DohmeTel. + 370 5 278 02 47msd_lietuva@merck.com<\/td><\/tr> Bulgaria<\/strong>Mark Harp and Doom Bulgaria BulgariaTel: +359 2 819 3737info-msdbg@merck.com<\/td> Luxembourg \/ Luxemburg<\/strong>MSD BelgiumTel: +32 (0) 2 776 62 11dpoc_belux@merck.com<\/td><\/tr> Czech Republic<\/strong>Merck Sharp & Dohme sroTel: +420 233 010 111dpoc_czechslovak@merck.com<\/td> Hungary<\/strong>MSD Pharma Hungary Kft.Tel .: +36 1 888 5300hungary_msd@merck.com<\/td><\/tr> Denmark<\/strong>MSD Danmark ApSTel: + 45 44 82 4000dkmail@merck.com<\/td> Malta<\/strong>Merck Sharp & Dohme Cyprus LimitedTel .: 8007 4433 (+356 99917558)malta_info@merck.com<\/td><\/tr> Germany<\/strong>MSD Sharp & Dohme GmbHTel: 0800 673 673 673 (+ 49 (0) 89 4561 0)e-mail@msd.de<\/td> The Netherlands<\/strong>Merck Sharp & Dohme BVTel: 0800 9999000 (+31 23 5153153)medicalinfo.nl@merck.com<\/td><\/tr> Eesti<\/strong>Merck Sharp & Dohme O\u00dcTel .: + 372 6144 200msdeesti@merck.com<\/td> Norway<\/strong>MSD (Norge) ASTel: +47 32 20 73 00msdnorge@msd.no<\/td><\/tr> Greece<\/strong>MSD \u0391.\u03a6.\u0392.\u0395.\u0395.:\u0397\u03bb: +30 210 98 97 300dpoc_greece@merck.com<\/td> Austria<\/strong>Merck Sharp & Dohme Ges.mbHTel: +43 (0) 1 26 044msd-medizin@merck.com<\/td><\/tr> Spain<\/strong>Merck Sharp & Dohme de Espa\u00f1a, SATel: +34 91 321 06 00msd_info@merck.com<\/td> Poland<\/strong>MSD Polska Sp. z ooTel .: +48 22 549 51 00msdpolska@merck.com<\/td><\/tr> France<\/strong>MSD FranceTel. +33 (0) 1 80 46 40 40<\/td> Portugal<\/strong>Merck Sharp & Dohme, LdaTel: +351 21 446 5700inform_pt@merck.com<\/td><\/tr> Croatia<\/strong>Merck Sharp & Dohme dooTel: + 385 1 6611 333croatia_info@merck.com<\/td> Romania<\/strong>Merck Sharp & Dohme Romania SRLTel .: + 40 21 529 2900msdromania@merck.com<\/td><\/tr> Ireland<\/strong>Merck Sharp & Dohme Ireland ( Human Health) LimitedTel: +353 (0) 1 2998700medinfo_ireland@merck.com<\/td> Slovenia<\/strong>Merck Sharp & Dohme, innovative zdravila dooTel: +386 1 5204 201msd.slovenia@merck.com<\/td><\/tr> Iceland<\/strong>Vistor hf.Phone: + 354 535 7000<\/td> Slovak Republic<\/strong>Merck Sharp & Dohme, sroTel: +421 2 58282010dpoc_czechslovak@merck.com<\/td><\/tr> Italy<\/strong>MSD Italia SrlTel: +39 06 361911medicalinformation.it@merck.com<\/td> Finland \/ Finland<\/strong>MSD Finland OyPuh \/ Tel: +358 (0) 9 804 650info@msd.fi<\/td><\/tr> .\u03a0\u03c1\u03bf\u03c2<\/strong>Merck Sharp & Dohme Cyprus Limited.:\u0397\u03bb .: 800 00 673 (+357 22866700)cyprus_info@merck.com<\/td> Sweden<\/strong>Merck Sharp & Dohme (Sweden) ABTel: +46 77 5700488medicinskinfo@merck.com<\/td><\/tr> Latvia<\/strong>SIA Merck Sharp & Dohme LatvijaTel: + 371-67364224msd_lv@merck.com<\/td> United Kingdom (Northern Ireland)<\/strong>Merck Sharp & Dohme Ireland ( Human Health) LimitedTel: +353 (0) 1 2998700medinfoNI@msd.com<\/td><\/tr><\/tbody><\/table><\/figure>\n","protected":false},"excerpt":{"rendered":"