{"id":19242,"date":"2022-03-04T16:29:46","date_gmt":"2022-03-04T16:29:46","guid":{"rendered":"https:\/\/zeepedia.com\/?p=19242"},"modified":"2022-03-07T16:23:16","modified_gmt":"2022-03-07T16:23:16","slug":"novorapid-flexpen","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/novorapid-flexpen\/","title":{"rendered":"Novo`Rapid FlexPen &#8211; Insulin aspart uses, dose and side effects"},"content":{"rendered":"\n<p>100 units\/ml solution for injection in a pre-filled pen<br>insulin\u00a0aspart<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What NovoRapid FlexPen is and what it is used for<\/h2>\n\n\n\n<p>NovoRapid is modern\u00a0insulin\u00a0(insulin analog) that is fast-acting.\u00a0Modern\u00a0insulins\u00a0are improved versions of human\u00a0insulin.<\/p>\n\n\n\n<p>NovoRapid is used for lowering high blood sugar in adults, adolescents, and children 1 year of age or older with\u00a0diabetes\u00a0(\u00a0diabetes mellitus\u00a0).\u00a0Diabetes\u00a0is a disease in which your body does not produce enough\u00a0insulin\u00a0to keep your blood sugar levels under control.\u00a0Treatment with NovoRapid helps prevent complications of your\u00a0diabetes.<\/p>\n\n\n\n<p>NovoRapid starts lowering your blood sugar 10-20 minutes after you inject it.&nbsp;The effect is strongest 1-3 hours after&nbsp;injection&nbsp;and lasts for 3-5 hours.&nbsp;Due to the short duration of action, NovoRapid should normally be taken in combination with medium- or long-acting insulin preparations.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before using NovoRapid FlexPen<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use NovoRapid<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to&nbsp;insulin&nbsp;aspart or any of the other ingredients of this medicine (see section 6, Contents of the pack and other information).<\/li><li>if you feel you are experiencing insulin sensation (symptoms of low blood sugar) (see a) Summary of serious and very common&nbsp;side effects&nbsp;in section 4).<\/li><li>if FlexPen has been dropped, damaged or shocked.<\/li><li>if&nbsp;your insulin&nbsp;has not been stored properly or frozen (see section 5, How to store NovoRapid).<\/li><li>if the insulin&nbsp;solution is&nbsp;not clear and colorless.<\/li><\/ul>\n\n\n\n<p>If any of these apply to you, do not use NovoRapid.\u00a0Talk to a doctor, nurse, or pharmacist.<\/p>\n\n\n\n<p><strong>Before using NovoRapid<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Check on the label that it is the right kind of&nbsp;insulin&nbsp;.<\/li><li>Always use a new injection needle for each&nbsp;injection&nbsp;to prevent contamination.<\/li><li>Injection needles and NovoRapid FlexPen must not be shared with anyone else.<\/li><li>NovoRapid FlexPen should only be injected under the skin.&nbsp;Talk to your doctor if you need to inject your&nbsp;insulin&nbsp;using another method.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Certain conditions and activities may affect your need for\u00a0insulin.\u00a0Consult a doctor:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you have problems with your kidneys, liver, adrenal glands,&nbsp;pituitary gland&nbsp;or thyroid gland.<\/li><li>if you exercise more than usual or want to change your diet, as this can affect your blood sugar level.<\/li><li>if you become ill: continue to take your&nbsp;insulin&nbsp;and consult a doctor.<\/li><li>if you are traveling abroad: travel over different time zones can affect your insulin needs and when to&nbsp;inject&nbsp;.<\/li><\/ul>\n\n\n\n<p><strong>Skin changes at the injection site<\/strong><\/p>\n\n\n\n<p>To help prevent changes in the adipose tissue under the skin, e.g.\u00a0skin thickening, skin shrinkage, or lumps under the skin, you should always change the injection site.\u00a0Insulin\u00a0may\u00a0not work as well if you inject in a knotted area or a thickened or shrunken area (see \u201cHow to use NovoRapid\u201d).\u00a0Contact your doctor if you notice skin changes at the injection site and before changing the injection site if you are currently injecting in an affected area.\u00a0Your doctor may advise you to check your blood sugar more often and to adjust your insulin dose or the\u00a0dose\u00a0of other diabetes medicines.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children and young people<\/h2>\n\n\n\n<p>Do not give this medicine to children under 1 year of age as no&nbsp;clinical studies&nbsp;have been performed in children under 1 year of age.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and NovoRapid FlexPen<\/h2>\n\n\n\n<p>Tell your doctor, nurse, or pharmacist if you are taking or have recently taken or might take any other medicines.<\/p>\n\n\n\n<p>Some medicines affect your blood sugar level, which may mean that your insulin dose needs to be changed.&nbsp;Below is a list of the most common medicines that may affect your insulin treatment.<\/p>\n\n\n\n<p>Your blood sugar level may drop (hypoglycemia) if you take:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Other medicines to treat&nbsp;diabetes<\/li><li>MAO inhibitors&nbsp;(for the treatment of depression)<\/li><li>Beta-blockers&nbsp;(for the treatment of high&nbsp;blood pressure&nbsp;)<\/li><li>ACE inhibitors&nbsp;(for the treatment of certain heart diseases or high&nbsp;blood pressure&nbsp;)<\/li><li>Salicylates (analgesics and antipyretics)<\/li><li>Anabolic&nbsp;steroids&nbsp;(eg&nbsp;testosterone&nbsp;)<\/li><li>Sulfonamides&nbsp;(for the treatment of&nbsp;infections&nbsp;).<\/li><\/ul>\n\n\n\n<p>Your blood sugar level may rise (hyperglycemia) if you take:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Oral contraceptives (&nbsp;birth control pills&nbsp;)<\/li><li>Thiazides&nbsp;(for the treatment of high&nbsp;blood pressure&nbsp;or severe fluid retention)<\/li><li>Glucocorticoids&nbsp;(eg&nbsp;cortisone&nbsp;for the treatment of&nbsp;inflammation&nbsp;)<\/li><li>Thyroid hormones (for the treatment of thyroid diseases)<\/li><li>Sympathomimetics&nbsp;(eg&nbsp;adrenaline&nbsp;or&nbsp;salbutamol&nbsp;,&nbsp;terbutaline&nbsp;for the treatment of&nbsp;asthma&nbsp;)<\/li><li>Growth hormone&nbsp;(for stimulation of skeletal and body growth with a pronounced effect on the body&#8217;s metabolism)<\/li><li>Danazol (an agent that affects ovulation).<\/li><\/ul>\n\n\n\n<p>Octreotide and lanreotide (for the treatment of\u00a0acromegaly, an unusual hormonal disorder with\u00a0pituitary\u00a0overproduction one of\u00a0the growth hormone\u00a0usually in middle-aged adults) can either raise or lower your blood sugar level.<\/p>\n\n\n\n<p>Beta-blockers\u00a0(for the treatment of high\u00a0blood pressure\u00a0) may weaken or eliminate the first warning signs of low blood sugar.<\/p>\n\n\n\n<p><strong>Pioglitazone (tablets for the treatment of type 2&nbsp;diabetes&nbsp;)<\/strong><\/p>\n\n\n\n<p>Some patients who have had type 2\u00a0diabetes\u00a0and heart disease for many years or previous\u00a0strokes\u00a0developed\u00a0heart failure\u00a0during treatment with pioglitazone and\u00a0insulin.\u00a0Tell your doctor as soon as possible if you get signs of\u00a0heart failure\u00a0such as unexpected shortness of breath, rapid weight gain, or local swelling (\u00a0edema\u00a0).<\/p>\n\n\n\n<p>If you have taken any of these medicines, talk to your doctor, nurse, or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">NovoRapid and drink alcohol<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>If you drink alcohol, your need for&nbsp;insulin&nbsp;may change, as your blood sugar level may either rise or fall.&nbsp;Careful blood glucose monitoring is recommended.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>If you are pregnant, think you may be pregnant or are planning to have a baby, ask your doctor for advice before taking this medicine.&nbsp;NovoRapid can be used during pregnancy.&nbsp;The insulin dose may need to be changed during pregnancy and after delivery.&nbsp;Careful monitoring of your&nbsp;diabetes&nbsp;and counteracting low blood sugar is important for your baby&#8217;s health.<\/li><li>There are no restrictions on treatment with NovoRapid during breast-feeding.<\/li><\/ul>\n\n\n\n<p>Ask your doctor, nurse, or pharmacist for advice before taking this medicine during pregnancy or breastfeeding.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Ask your doctor if you can drive or use machines:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you often get low blood sugar levels.<\/li><li>if you find it difficult to recognize signs of low blood sugar (insulin detection).<\/li><\/ul>\n\n\n\n<p>If your blood sugar is low or high, then your ability to concentrate and react can be affected, and therefore also your ability to drive a vehicle or use machines.\u00a0Remember that you can\u00a0put\u00a0yourself and others at risk.<\/p>\n\n\n\n<p>The effect of NovoRapid is coming fast.\u00a0This means that if you get low blood sugar, you can feel it faster than after injection\u00a0of soluble human\u00a0insulin.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Important information about some of the ingredients of NovoRapid<\/h2>\n\n\n\n<p>NovoRapid contains less than 1 mmol\u00a0sodium\u00a0(23 mg) per\u00a0dose, ie NovoRapid is essential &#8216;sodium-free&#8217;.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to use NovoRapid FlexPen<\/h2>\n\n\n\n<p><strong>Dose&nbsp;and when you take your&nbsp;insulin<\/strong><\/p>\n\n\n\n<p>Always use your\u00a0insulin\u00a0and make dose adjustments exactly as your doctor advised.\u00a0If you are not sure, talk to your doctor, nurse, or pharmacist.<\/p>\n\n\n\n<p>NovoRapid is usually taken immediately before a meal.&nbsp;Eat a meal or snack within 10 minutes of&nbsp;injecting&nbsp;one to avoid low blood sugar.&nbsp;If needed, NovoRapid can also be injected shortly after a meal.&nbsp;For information, see below How and where to inject.<\/p>\n\n\n\n<p>Only change insulin preparations on the advice of a doctor.&nbsp;If your doctor has switched you from one type of insulin or brand of insulin to another, your&nbsp;dose&nbsp;may need to be adjusted by your doctor.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Use for children and adolescents<\/h2>\n\n\n\n<p>NovoRapid can be used in adolescents and children aged 1 year or older instead of soluble human\u00a0insulin\u00a0when it is good if the\u00a0insulin\u00a0acts quickly, for example when it is difficult to give the medicine to the child at the right time to meals.<\/p>\n\n\n\n<p><strong>Use for special patient groups<\/strong><\/p>\n\n\n\n<p>If you have impaired kidney or liver function or if you are over 65, you need to check your blood sugar more regularly and discuss changes in your insulin dose with your doctor.<\/p>\n\n\n\n<p><strong>How and where to inject<\/strong><\/p>\n\n\n\n<p>NovoRapid is for&nbsp;injection&nbsp;under the skin (&nbsp;subcutaneously&nbsp;).&nbsp;You should never inject yourself directly into a vein (&nbsp;intravenously&nbsp;) or muscle (&nbsp;intramuscularly&nbsp;).&nbsp;NovoRapid FlexPen should only be injected under the skin.&nbsp;Talk to your doctor if you need to inject your&nbsp;insulin&nbsp;using another method.<\/p>\n\n\n\n<p>At each\u00a0injection, change the injection site within the same specific skin area that you are using.\u00a0This may reduce the risk of developing lumps or pits in the skin (see section 4, Possible\u00a0side effects\u00a0).\u00a0The best area to\u00a0inject\u00a0one is on: the front of the waist (abdomen), the upper arm, or the front of the thighs.\u00a0Insulin\u00a0acts faster if injected into the front of the waist.\u00a0Always check your blood sugar regularly.<\/p>\n\n\n\n<p><strong>How to handle NovoRapid FlexPen<\/strong><\/p>\n\n\n\n<p>NovoRapid FlexPen is a pre-filled, color-coded&nbsp;pen&nbsp;containing&nbsp;insulin&nbsp;aspart.&nbsp;It is discarded when empty.<\/p>\n\n\n\n<p>Carefully read the instructions for use of the NovoRapid FlexPen contained in this leaflet.\u00a0You must use the pen according to the instructions for using the NovoRapid FlexPen.<\/p>\n\n\n\n<p>Always make sure you use the correct pen before injecting your insulin.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you take more insulin than you should<\/h2>\n\n\n\n<p>If you take too much\u00a0insulin, your blood sugar may become too low (hypoglycemia).\u00a0See a) Summary of serious and very common\u00a0side effects\u00a0in section 4.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to take your insulin<\/h2>\n\n\n\n<p>If you forget to take your\u00a0insulin, your blood sugar may become too high (hyperglycemia).\u00a0See c)\u00a0Diabetes Disorders\u00a0in Section 4.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop taking your insulin<\/h2>\n\n\n\n<p>Do not stop taking insulin without talking to your doctor, who will tell you what needs to be done.\u00a0It can lead to very high blood sugar (severe\u00a0hyperglycemia) and\u00a0ketoacidosis.\u00a0See c)\u00a0Diabetes Disorders\u00a0in Section 4.<\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor, nurse, or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p><strong>a) Summary of serious and very common&nbsp;side&nbsp;effects<\/strong><\/p>\n\n\n\n<p><strong>Low blood sugar (\u00a0hypoglycemia\u00a0)<\/strong>\u00a0is a very common\u00a0side effect.\u00a0It can occur in more than 1 in 10 users.<\/p>\n\n\n\n<p>Low blood sugar can occur if you:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>injecting too much&nbsp;insulin&nbsp;.<\/li><li>eat too little or skip a meal.<\/li><li>exercise more than usual.<\/li><li>drink alcohol (see NovoRapid and drinking alcohol in section 2).<\/li><\/ul>\n\n\n\n<p>Signs of low blood sugar: Cold sweats;&nbsp;cool and pale skin;&nbsp;headache;&nbsp;palpitation;&nbsp;nausea;&nbsp;strong hunger;&nbsp;temporary vision changes;&nbsp;drowsiness;&nbsp;unusual fatigue and weakness;&nbsp;anxiety or trembling;&nbsp;feelings of anxiety;&nbsp;confusion;&nbsp;concentration difficulties.<\/p>\n\n\n\n<p>Very low blood sugar can lead to unconsciousness.\u00a0If left untreated for very long periods, very low blood sugar can cause brain damage (temporary or permanent) and even death.\u00a0You can regain consciousness faster if you receive an\u00a0injection\u00a0of the\u00a0hormone\u00a0et glucagon from someone who knows how to use it.\u00a0If you are given glucagon, you will need\u00a0glucose\u00a0or a sugar-containing snack as soon as you regain consciousness.\u00a0If you do not respond to glucagon therapy, you will need to be treated in hospital.<\/p>\n\n\n\n<p>What to do if you get low blood sugar:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>If you feel that your blood sugar is too low, eat grape sugar tablets or any other snack that contains a lot of sugar (sweets, cakes, fruit juice).&nbsp;If possible, check your blood sugar and rest.&nbsp;Always take glucose tablets or snacks with a lot of sugar in them for safety.<\/li><li>When the symptoms of low blood sugar have disappeared or when your blood sugar level has stabilized, you should continue with the insulin treatment as usual.<\/li><li>If you have had low blood sugar and lost consciousness or if you have needed a glucagon&nbsp;injection&nbsp;, or if you have had many insulin sensations, talk to a doctor.&nbsp;The amount of&nbsp;insulin&nbsp;or when you take it, diet or exercise may need to be adjusted.<\/li><\/ul>\n\n\n\n<p>Tell them that you have\u00a0diabetes\u00a0for people who need to know it, what the consequences can be, and also the risk of becoming unconscious due to low blood sugar.\u00a0Tell them that if you become unconscious, they should put you on the side and get medical attention immediately.\u00a0They must not give you anything to eat or drink as there is a risk that you will suffocate.<\/p>\n\n\n\n<p><strong>Severe allergic reactions<\/strong>\u00a0to NovoRapid or any of the other ingredients (so-called systemic\u00a0allergic reaction\u00a0) are very rare but can be life-threatening.\u00a0It may affect less than 1 in 10,000 users.<\/p>\n\n\n\n<p>Contact a doctor immediately:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if signs of&nbsp;allergy&nbsp;spread to other parts of the body.<\/li><li>if you suddenly feel unwell and you: start sweating;&nbsp;begins to vomit;&nbsp;have difficulty breathing;&nbsp;get palpitations;&nbsp;feel dizzy.<\/li><\/ul>\n\n\n\n<p>If you experience any of these, seek medical attention immediately.<\/p>\n\n\n\n<p><strong>Skin changes at the injection site:<\/strong>&nbsp;If you inject&nbsp;insulin&nbsp;at the same site, the adipose tissue may either shrink (lipoatrophy) or thicken (lipohypertrophy) (may affect up to 1 in 100 people).&nbsp;Nodules under the skin can also be caused by the accumulation of a&nbsp;protein&nbsp;called amyloid (&nbsp;cutaneous&nbsp;amyloidosis. How often this occurs is not known).&nbsp;Insulin&nbsp;may&nbsp;not work as well if you inject in an area with lumps or in a thickened or shrunken area.&nbsp;Change the injection site for each&nbsp;injection&nbsp;to prevent these skin changes.<\/p>\n\n\n\n<p><strong>b) List of other&nbsp;side&nbsp;effects<\/strong><\/p>\n\n\n\n<p><strong>Uncommon&nbsp;side effects&nbsp;are<\/strong><\/p>\n\n\n\n<p>May affect less than 1 in 100 users.<\/p>\n\n\n\n<p><strong>Signs of allergy:<\/strong>\u00a0Local allergic reactions (pain,\u00a0redness,\u00a0hives,\u00a0inflammation, bruising, swelling, and\u00a0itching\u00a0) may occur at the injection site.\u00a0These symptoms usually go away after taking your\u00a0insulin\u00a0for a few weeks.\u00a0If they do not disappear or spread throughout the body, talk to a doctor immediately.\u00a0See also Severe allergic reactions above.<\/p>\n\n\n\n<p><strong>Vision problems:<\/strong>&nbsp;At the beginning of insulin treatment, visual disturbances may occur, but these are usually temporary.<\/p>\n\n\n\n<p><strong>Swollen joints:<\/strong>\u00a0When you start taking\u00a0insulin, your body may bind water, causing you to swell around the ankles and other joints.\u00a0This usually goes away soon, otherwise, you should talk to a doctor.<\/p>\n\n\n\n<p><strong>Diabetic\u00a0retinopathy\u00a0<\/strong>(an eye disease associated with\u00a0diabetes\u00a0and can lead to loss of vision): If you have diabetic\u00a0retinopathy, it can worsen if your blood sugar level improves very quickly.\u00a0Ask your doctor about this.<\/p>\n\n\n\n<p><strong>Rare&nbsp;side&nbsp;effects<\/strong><\/p>\n\n\n\n<p>May affect less than 1 in 1,000 users.<\/p>\n\n\n\n<p><strong>Painful&nbsp;neuropathy<\/strong>&nbsp;(pain due to nerve damage): If your blood sugar level improves very quickly, you may get nerve-related pain.&nbsp;This is called&nbsp;acute&nbsp;painful&nbsp;neuropathy&nbsp;and is usually transient.<\/p>\n\n\n\n<p><strong>c) Problems with&nbsp;diabetes<\/strong><\/p>\n\n\n\n<p><strong>High blood sugar (hyperglycemia)<\/strong><\/p>\n\n\n\n<p>High blood sugar can occur if you:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>have not injected enough&nbsp;insulin&nbsp;.<\/li><li>forget to take your&nbsp;insulin&nbsp;or stop taking&nbsp;insulin&nbsp;.<\/li><li>repeatedly take less&nbsp;insulin&nbsp;than you need.<\/li><li>gets an&nbsp;infection&nbsp;and \/ or fever.<\/li><li>eat more than usual.<\/li><li>exercise less than usual.<\/li><\/ul>\n\n\n\n<p>High blood sugar warning signs:<\/p>\n\n\n\n<p>The warning signals appear gradually.&nbsp;They manifest as: increased urine output;&nbsp;thirst;&nbsp;loss of appetite;&nbsp;feeling sick (nausea or vomiting);&nbsp;drowsiness or fatigue;&nbsp;redness;&nbsp;dry skin;&nbsp;dry mouth&nbsp;and a breath that smells of fruit (acetone).<\/p>\n\n\n\n<p>What should I do if I get high blood sugar:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>If you get any of the above warning signs: check your blood sugar, do a ketone test on your urine if possible and then contact a doctor immediately.<\/li><li>The symptoms can be a sign of a very serious condition called diabetic&nbsp;ketoacidosis&nbsp;(accumulation of acid in the blood when the body breaks down fat instead of sugar).&nbsp;If left untreated, it can lead to diabetic coma and eventually death.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">How to store NovoRapid FlexPen<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the label and carton of FlexPen after &#8220;EXP&#8221;.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>The pen cap should be on your FlexPen when you are not using it.&nbsp;Sensitive to light.&nbsp;NovoRapid must be protected from strong heat and light.<\/p>\n\n\n\n<p><strong>Unopened packaging:<\/strong>\u00a0Unused NovoRapid FlexPen should be stored in a refrigerator from 2 \u00b0 C to 8 \u00b0 C, not near the cooling element.\u00a0Do not freeze.<\/p>\n\n\n\n<p><strong>During use or included as a spare:<\/strong>&nbsp;You can take your NovoRapid FlexPen with you and store it at a temperature not exceeding 30 \u00b0 C or in a refrigerator (2 \u00b0 C to 8 \u00b0 C) for up to 4 weeks.&nbsp;When storing in a refrigerator, do not store it near the refrigerator.&nbsp;Do not freeze.<\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the pack and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is&nbsp;insulin&nbsp;aspart.&nbsp;Each ml contains 100 units of&nbsp;insulin&nbsp;aspart.&nbsp;Each pre-filled&nbsp;pen&nbsp;contains 300 units of&nbsp;insulin&nbsp;aspart in 3 ml&nbsp;solution for injection&nbsp;.<\/li><li>The other ingredients are&nbsp;glycerol&nbsp;, phenol, metacresol, zinc chloride, disodium phosphate dihydrate, sodium chloride,&nbsp;hydrochloric acid&nbsp;, sodium hydroxide and water for injections.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and contents of the pack<\/h2>\n\n\n\n<p>NovoRapid is in the form of a\u00a0solution for injection.<\/p>\n\n\n\n<p>Pack sizes: 1 (with or without needles), 5 (without needles), and 10 (without needles) 3 ml pre-filled pens.\u00a0Not all pack sizes may be marketed.<\/p>\n\n\n\n<p>The solution is clear and colorless.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p><strong>Marketing Authorisation Holder<\/strong><\/p>\n\n\n\n<p>Novo Nordisk A \/ S, Novo All\u00e9, DK-2880 Bagsv\u00e6rd, Denmark<\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>The manufacturer can be identified by the batch number printed on the tab on the carton and the label:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>If the second and third characters are S6, P5, K7, R7, VG, FG or ZF, the manufacturer is Novo Nordisk A \/ S, Novo All\u00e9, DK-2880 Bagsv\u00e6rd, Denmark<\/li><li>If the second and third characters are H7 or T6, the manufacturer is Novo Nordisk Production SAS, 45 Avenue d&#8217;Orl\u00e9ans, F-28000 Chartres, France.<\/li><\/ul>\n","protected":false},"excerpt":{"rendered":"<p>NovoRapid is a modern insulin (insulin analogue) that is fast-acting. Modern insulins are improved versions of human insulin .<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,15581],"tags":[19209,2924,2927,19204,19208,19207,12646,12645,19205,19206],"class_list":["post-19242","post","type-post","status-publish","format-standard","hentry","category-medicines","category-n","tag-benefits-of-novorapid-flexpen","tag-insulin-aspart","tag-insulin-aspart-side-effects","tag-novorapid-flexpen","tag-novorapid-flexpen-insulin","tag-novorapid-flexpen-side-effects","tag-what-insulin-aspart-is-used-for","tag-what-is-insulin-aspart","tag-what-is-novorapid-flexpen","tag-what-novorapid-flexpen-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/19242","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=19242"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/19242\/revisions"}],"predecessor-version":[{"id":19272,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/19242\/revisions\/19272"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=19242"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=19242"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=19242"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}