{"id":19240,"date":"2022-03-04T16:28:02","date_gmt":"2022-03-04T16:28:02","guid":{"rendered":"https:\/\/zeepedia.com\/?p=19240"},"modified":"2022-03-07T16:23:22","modified_gmt":"2022-03-07T16:23:22","slug":"novorapid","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/novorapid\/","title":{"rendered":"NovoRapid &#8211; Insulin aspart vial uses, dose and side effects"},"content":{"rendered":"\n<p>100 units\/ml\u00a0solution for\u00a0injection in<br>insulin\u00a0aspart vial<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What NovoRapid is and what it is used for<\/h2>\n\n\n\n<p>NovoRapid is modern\u00a0insulin\u00a0(insulin analog) that is fast-acting.\u00a0Modern\u00a0insulins\u00a0are improved versions of human\u00a0insulin.<\/p>\n\n\n\n<p>NovoRapid is used for lowering high blood sugar in adults, adolescents, and children 1 year of age or older with\u00a0diabetes\u00a0(\u00a0diabetes mellitus\u00a0).\u00a0Diabetes\u00a0is a disease in which your body does not produce enough\u00a0insulin\u00a0to keep your blood sugar levels under control.\u00a0Treatment with NovoRapid helps prevent complications of your\u00a0diabetes.<\/p>\n\n\n\n<p>NovoRapid starts lowering your blood sugar 10-20 minutes after you inject it.\u00a0The effect is strongest 1-3 hours after\u00a0injection\u00a0and lasts for 3-5 hours.\u00a0Due to the short duration of action, NovoRapid should normally be taken in combination with medium- or long-acting insulin preparations.\u00a0NovoRapid can also be used in insulin pumps for\u00a0continuous\u00a0infusion.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before using NovoRapid<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use NovoRapid<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to&nbsp;insulin&nbsp;aspart or any of the other ingredients of this medicine (see section 6, Contents of the pack and other information). If you are allergic to&nbsp;insulin&nbsp;aspart or any of the other ingredients of this medicine (see section 6, content and other information).<\/li><li>if you feel you are starting to feel insulin (low blood sugar symptoms) (see a) Summary of serious and very common&nbsp;side effects&nbsp;are in section 4) .if you feel you are starting to feel insulin (low blood sugar symptoms) (see a) Summary of serious and very common&nbsp;side effects&nbsp;are in section 4).<\/li><li>if the protective cover has come loose or is missing.&nbsp;Each&nbsp;vial&nbsp;has a tamper-evident plastic protective cap.&nbsp;If the cap is not completely intact when you receive the bottle, return it to the pharmacist.<\/li><li>if&nbsp;your insulin&nbsp;has not been stored properly or frozen (see section 5, How to store NovoRapid).<\/li><li>if the insulin&nbsp;solution is&nbsp;not clear and colorless.<\/li><\/ul>\n\n\n\n<p>If any of these apply to you, do not use NovoRapid.\u00a0Talk to a doctor, nurse, or pharmacist.<\/p>\n\n\n\n<p><strong>Before using NovoRapid<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Check on the label that it is the right kind of&nbsp;insulin&nbsp;.<\/li><li>Remove the protective cap.<\/li><li>Always use a new injection needle for each&nbsp;injection&nbsp;to prevent contamination.<\/li><li>Injection needles and syringes must not be shared with anyone else.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Certain conditions and activities may affect your need for\u00a0insulin.\u00a0Consult a doctor:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you have problems with your kidneys, liver, adrenal glands,&nbsp;pituitary gland&nbsp;or thyroid gland.<\/li><li>if you exercise more than usual or want to change your diet, as this can affect your blood sugar level.<\/li><li>if you become ill: continue to take your&nbsp;insulin&nbsp;and consult a doctor.<\/li><li>if you are traveling abroad: travel over different time zones can affect your insulin needs and when to&nbsp;inject&nbsp;.<\/li><\/ul>\n\n\n\n<p><strong>Skin changes at the injection site<\/strong><\/p>\n\n\n\n<p>To help prevent changes in the adipose tissue under the skin, e.g.\u00a0skin thickening, skin shrinkage, or lumps under the skin, you should always change the injection site.\u00a0Insulin\u00a0may\u00a0not work as well if you inject in a knotted area or a thickened or shrunken area (see \u201cHow to use NovoRapid\u201d).\u00a0Contact your doctor if you notice skin changes at the injection site and before changing the injection site if you are currently injecting in an affected area.\u00a0Your doctor may advise you to check your blood sugar more often and to adjust your insulin dose or the\u00a0dose\u00a0of other diabetes medicines.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children and young people<\/h2>\n\n\n\n<p>Do not give this medicine to children under 1 year of age as no&nbsp;clinical studies&nbsp;have been performed in children under 1 year of age.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and NovoRapid<\/h2>\n\n\n\n<p>Tell your doctor, nurse, or pharmacist if you are taking or have recently taken or might take any other medicines.<\/p>\n\n\n\n<p>Some medicines affect your blood sugar level, which may mean that your insulin dose needs to be changed.&nbsp;Below is a list of the most common medicines that may affect your insulin treatment.<\/p>\n\n\n\n<p>Your blood sugar level may drop (hypoglycemia) if you take:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Other medicines to treat&nbsp;diabetes<\/li><li>MAO inhibitors&nbsp;(for the treatment of depression)<\/li><li>Beta-blockers&nbsp;(for the treatment of high&nbsp;blood pressure&nbsp;)<\/li><li>ACE inhibitors&nbsp;(for the treatment of certain heart diseases or high&nbsp;blood pressure&nbsp;)<\/li><li>Salicylates (analgesics and antipyretics)<\/li><li>Anabolic&nbsp;steroids&nbsp;(eg&nbsp;testosterone&nbsp;)<\/li><li>Sulfonamides&nbsp;(for the treatment of&nbsp;infections&nbsp;).<\/li><\/ul>\n\n\n\n<p>Your blood sugar level may rise (hyperglycemia) if you take:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Oral contraceptives (&nbsp;birth control pills&nbsp;)<\/li><li>Thiazides&nbsp;(for the treatment of high&nbsp;blood pressure&nbsp;or severe fluid retention)<\/li><li>Glucocorticoids&nbsp;(eg&nbsp;cortisone&nbsp;for the treatment of&nbsp;inflammation&nbsp;)<\/li><li>Thyroid hormones (for the treatment of thyroid diseases)<\/li><li>Sympathomimetics&nbsp;(eg&nbsp;adrenaline&nbsp;or&nbsp;salbutamol&nbsp;,&nbsp;terbutaline&nbsp;for the treatment of&nbsp;asthma&nbsp;)<\/li><li>Growth hormone&nbsp;(for stimulation of skeletal and body growth with a pronounced effect on the body&#8217;s metabolism)<\/li><li>Danazol (an agent that affects ovulation).<\/li><\/ul>\n\n\n\n<p>Octreotide and lanreotide (for the treatment of\u00a0acromegaly, an unusual hormonal disorder with\u00a0pituitary\u00a0overproduction one of\u00a0the growth hormone\u00a0usually in middle-aged adults) can either raise or lower your blood sugar level.<\/p>\n\n\n\n<p>Beta-blockers\u00a0(for the treatment of high\u00a0blood pressure\u00a0) may weaken or eliminate the first warning signs of low blood sugar.<\/p>\n\n\n\n<p><strong>Pioglitazone (tablets for the treatment of type 2&nbsp;diabetes&nbsp;)<\/strong><\/p>\n\n\n\n<p>Some patients who have had type 2\u00a0diabetes\u00a0and heart disease for many years or previous\u00a0strokes\u00a0developed\u00a0heart failure\u00a0during treatment with pioglitazone and\u00a0insulin.\u00a0Tell your doctor as soon as possible if you get signs of\u00a0heart failure\u00a0such as unexpected shortness of breath, rapid weight gain, or local swelling (\u00a0edema\u00a0).<\/p>\n\n\n\n<p>If you have taken any of these medicines, talk to your doctor, nurse, or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">NovoRapid and drink alcohol<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>If you drink alcohol, your need for&nbsp;insulin&nbsp;may change, as your blood sugar level may either rise or fall.&nbsp;Careful blood glucose monitoring is recommended.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>If you are pregnant, think you may be pregnant or are planning to have a baby, ask your doctor for advice before taking this medicine.&nbsp;NovoRapid can be used during pregnancy.&nbsp;The insulin dose may need to be changed during pregnancy and after delivery.&nbsp;Careful monitoring of your&nbsp;diabetes&nbsp;and counteracting low blood sugar is important for your baby&#8217;s health.<\/li><li>There are no restrictions on treatment with NovoRapid during breast-feeding.<\/li><\/ul>\n\n\n\n<p>Ask your doctor, nurse, or pharmacist for advice before taking this medicine during pregnancy or breastfeeding.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Ask your doctor if you can drive or use machines:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you often get low blood sugar levels.<\/li><li>if you find it difficult to recognize signs of low blood sugar (insulin detection).<\/li><\/ul>\n\n\n\n<p>If your blood sugar is low or high, then your ability to concentrate and react can be affected, and therefore also your ability to drive a vehicle or use machines.\u00a0Remember that you can\u00a0put\u00a0yourself and others at risk.<\/p>\n\n\n\n<p>The effect of NovoRapid is coming fast.\u00a0This means that if you get low blood sugar, you can feel it faster than after injection\u00a0of soluble human\u00a0insulin.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Important information about some of the ingredients of NovoRapid<\/h2>\n\n\n\n<p>NovoRapid contains less than 1 mmol\u00a0sodium\u00a0(23 mg) per\u00a0dose, ie NovoRapid is essential &#8216;sodium-free&#8217;.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to use NovoRapid<\/h2>\n\n\n\n<p><strong>Dose&nbsp;and when you take your&nbsp;insulin<\/strong><\/p>\n\n\n\n<p>Always use your\u00a0insulin\u00a0and make dose adjustments exactly as your doctor advised.\u00a0If you are not sure, talk to your doctor, nurse, or pharmacist.<\/p>\n\n\n\n<p>NovoRapid is usually taken immediately before a meal.&nbsp;Eat a meal or snack within 10 minutes of&nbsp;injecting&nbsp;one to avoid low blood sugar.&nbsp;If needed, NovoRapid can also be injected shortly after a meal.&nbsp;For information, see below How and where to inject.<\/p>\n\n\n\n<p>Only change insulin preparations on the advice of a doctor.&nbsp;If your doctor has switched you from one type of insulin or brand of insulin to another, your&nbsp;dose&nbsp;may need to be adjusted by your doctor.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Use for children and adolescents<\/h2>\n\n\n\n<p>NovoRapid can be used in adolescents and children aged 1 year or older instead of soluble human\u00a0insulin\u00a0when it is good if the\u00a0insulin\u00a0acts quickly, for example when it is difficult to give the medicine to the child at the right time about meals.<\/p>\n\n\n\n<p><strong>Use for special patient groups<\/strong><\/p>\n\n\n\n<p>If you have impaired kidney or liver function or if you are over 65, you need to check your blood sugar more regularly and discuss changes in your insulin dose with your doctor.<\/p>\n\n\n\n<p><strong>How and where to inject<\/strong><\/p>\n\n\n\n<p>NovoRapid is for\u00a0injection\u00a0under the skin (\u00a0subcutaneously\u00a0) or continuous\u00a0infusion\u00a0with a pump system.\u00a0Administration\u00a0with a pump requires detailed instructions from healthcare professionals.\u00a0You should never inject yourself directly into a vein (\u00a0intravenously\u00a0) or muscle (\u00a0intramuscularly\u00a0).\u00a0If needed, NovoRapid can be given directly into a vein, but this should only be done by a doctor or other healthcare professional.<\/p>\n\n\n\n<p>At each\u00a0injection, change the injection site within the same specific skin area that you are using.\u00a0This may reduce the risk of developing lumps or pits in the skin (see section 4, Possible\u00a0side effects\u00a0).\u00a0The best area to\u00a0inject\u00a0one is on: the front of the waist (abdomen), the upper arm, or the front of the thighs.\u00a0Insulin\u00a0acts faster if injected into the front of the waist.\u00a0Always check your blood sugar regularly.<\/p>\n\n\n\n<p>NPH (Neutral Protamine Hawthorn) insulin is the only type of insulin that can be mixed with NovoRapid and the\u00a0mixture\u00a0must be injected immediately under the skin (\u00a0subcutaneously\u00a0).\u00a0NovoRapid should be withdrawn into the syringe before withdrawing your NPH\u00a0insulin.<\/p>\n\n\n\n<p><strong>How to use NovoRapid<\/strong><\/p>\n\n\n\n<p><em>If you only use one type of insulin<\/em><\/p>\n\n\n\n<ol class=\"wp-block-list\"><li>Inhale the same amount of air into the syringe that corresponds to the dose of insulin you intend to inject.&nbsp;Inject the air into the vial.<\/li><li>Turn the vial and syringe upside down and draw the correct dose of insulin into the syringe.&nbsp;Pull the needle out of the vial.&nbsp;Then spray&nbsp;the air out of the syringe and check that the&nbsp;dose&nbsp;is correct.<\/li><\/ol>\n\n\n\n<p><em>If you mix two types of insulin<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Shortly before&nbsp;injection&nbsp;, roll the vial of NPH&nbsp;insulin&nbsp;between your hands until the liquid is evenly white and cloudy.<\/li><li>2. Draw an equal amount of air into the syringe corresponding to the&nbsp;dose&nbsp;of NPH&nbsp;insulin&nbsp;.&nbsp;Inject the air into the vial containing the NPH&nbsp;insulin&nbsp;and pull out the injection needle.<\/li><li>3. Draw an equal amount of air into the syringe that corresponds to&nbsp;dose&nbsp;one of NovoRapid.&nbsp;Inject the air into the vial containing NovoRapid.&nbsp;Turn the vial and syringe upside down and withdraw the prescribed&nbsp;dose&nbsp;of NovoRapid.&nbsp;Squirt&nbsp;any air out of the syringe and check that the&nbsp;dose&nbsp;is correct.<\/li><li>4. Insert the needle into the vial of NPH&nbsp;insulin&nbsp;, turn the vial and syringe upside down and draw up the prescribed&nbsp;dose&nbsp;.&nbsp;Squirt&nbsp;any air out of the syringe and check&nbsp;dose&nbsp;one.&nbsp;Inject the&nbsp;mixture&nbsp;immediately.<\/li><li>5. Always mix NovoRapid and NPH&nbsp;insulin&nbsp;in the above order.<\/li><\/ul>\n\n\n\n<p><strong>How NovoRapid is injected<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Inject&nbsp;insulin&nbsp;under the skin.&nbsp;Use the injection technique shown to you by your doctor or nurse.<\/li><li>Hold the injection needle under the skin for at least 6 seconds to ensure that the entire&nbsp;dose&nbsp;has been injected.<\/li><li>Discard the injection needle after each&nbsp;injection&nbsp;.<\/li><\/ul>\n\n\n\n<p><strong>When used in insulin pump<\/strong><\/p>\n\n\n\n<p>NovoRapid must never be mixed with any other&nbsp;insulin&nbsp;when used in an insulin pump.<\/p>\n\n\n\n<p>Follow your doctor&#8217;s instructions and recommendations for using NovoRapid in the insulin pump.\u00a0Before using NovoRapid in the pump system, you must have detailed instructions on how to use the pump and information on what to do if you become ill, have high or low blood sugar, or if the pump stops working.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Before inserting the injection needle, wash your hands and the infusion site with soap and water to avoid&nbsp;infusion&nbsp;at the infusion site.<\/li><li>When filling a new container (&nbsp;syringe&nbsp;), make sure that you do not leave any large air bubbles in either the syringe or the hose.<\/li><li>The infusion set (tubing and injection needle) should be replaced according to the instructions in the instructions for use provided with the infusion set.<\/li><\/ul>\n\n\n\n<p>To benefit from the insulin infusion and to detect any defects in the insulin pump, check your blood sugar level regularly.<\/p>\n\n\n\n<p><strong>What to do if the insulin pump stops working<\/strong><\/p>\n\n\n\n<p>You should always have an alternative method of\u00a0injecting\u00a0your\u00a0insulin\u00a0under the skin in case of the insulin pump malfunctions.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you take more insulin than you should<\/h2>\n\n\n\n<p>If you take too much\u00a0insulin, your blood sugar may become too low (hypoglycemia).\u00a0See a) Summary of serious and very common\u00a0side effects\u00a0in section 4.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to take your insulin<\/h2>\n\n\n\n<p>If you forget to take your\u00a0insulin, your blood sugar may become too high (hyperglycemia).\u00a0See c)\u00a0Diabetes Disorders\u00a0in Section 4.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop taking your insulin<\/h2>\n\n\n\n<p>Do not stop insulin treatment without talking to a doctor, who will tell you what needs to be done.\u00a0It can lead to very high blood sugar (severe\u00a0hyperglycemia) and\u00a0ketoacidosis.\u00a0See c)\u00a0Diabetes Disorders\u00a0in Section 4.<\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor, nurse, or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p><strong>a) Summary of serious and very common&nbsp;side&nbsp;effects<\/strong><\/p>\n\n\n\n<p><strong>Low blood sugar (\u00a0hypoglycemia\u00a0)<\/strong>\u00a0is a very common\u00a0side effect.\u00a0It can occur in more than 1 in 10 users.<\/p>\n\n\n\n<p>Low blood sugar can occur if you:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>injecting too much&nbsp;insulin&nbsp;.<\/li><li>eat too little or skip a meal.<\/li><li>exercise more than usual.<\/li><li>drink alcohol (see NovoRapid and drinking alcohol in section 2).<\/li><\/ul>\n\n\n\n<p>Signs of low blood sugar: Cold sweats;&nbsp;cool and pale skin;&nbsp;headache;&nbsp;palpitation;&nbsp;nausea;&nbsp;strong hunger;&nbsp;temporary vision changes;&nbsp;drowsiness;&nbsp;unusual fatigue and weakness;&nbsp;anxiety or trembling;&nbsp;feelings of anxiety;&nbsp;confusion;&nbsp;concentration difficulties.<\/p>\n\n\n\n<p>Very low blood sugar can lead to unconsciousness.\u00a0If left untreated for very long periods, very low blood sugar can cause brain damage (temporary or permanent) and even death.\u00a0You can regain consciousness faster if you receive an\u00a0injection\u00a0of the\u00a0hormone\u00a0et glucagon from someone who knows how to use it.\u00a0If you are given glucagon, you will need\u00a0glucose\u00a0or a sugar-containing snack as soon as you regain consciousness.\u00a0If you do not respond to glucagon therapy, you will need to be treated in hospital.<\/p>\n\n\n\n<p>What to do if you get low blood sugar:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>If you feel that your blood sugar is too low, eat grape sugar tablets or any other snack that contains a lot of sugar (sweets, cakes, fruit juice).&nbsp;If possible, check your blood sugar and rest.&nbsp;Always take glucose tablets or snacks with a lot of sugar in them for safety.<\/li><li>When the symptoms of low blood sugar have disappeared or when your blood sugar level has stabilized, you should continue with the insulin treatment as usual.<\/li><li>If you have had low blood sugar and lost consciousness or if you have needed a glucagon&nbsp;injection&nbsp;, or if you have had many insulin sensations, talk to a doctor.&nbsp;The amount of&nbsp;insulin&nbsp;or when you take it, diet or exercise may need to be adjusted.<\/li><\/ul>\n\n\n\n<p>Tell them that you have\u00a0diabetes\u00a0for people who need to know it, what the consequences can be, and also the risk of becoming unconscious due to low blood sugar.\u00a0Tell them that if you become unconscious, they should put you on the side and get medical attention immediately.\u00a0They must not give you anything to eat or drink as there is a risk that you will suffocate.<\/p>\n\n\n\n<p><strong>Severe allergic reactions<\/strong>\u00a0to NovoRapid or any of the other ingredients (so-called systemic\u00a0allergic reaction\u00a0) are very rare but can be life-threatening.\u00a0It may affect less than 1 in 10,000 users.<\/p>\n\n\n\n<p>Contact a doctor immediately:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if signs of&nbsp;allergy&nbsp;spread to other parts of the body.<\/li><li>if you suddenly feel unwell and you: start sweating;&nbsp;begins to vomit;&nbsp;have difficulty breathing;&nbsp;get palpitations;&nbsp;feel dizzy.<\/li><\/ul>\n\n\n\n<p>If you experience any of these, seek medical attention immediately.<\/p>\n\n\n\n<p><strong>Skin changes at the injection site:<\/strong>&nbsp;If you inject&nbsp;insulin&nbsp;at the same site, the adipose tissue may either shrink (lipoatrophy) or thicken (lipohypertrophy) (may affect up to 1 in 100 people).&nbsp;Nodules under the skin can also be caused by the accumulation of a&nbsp;protein&nbsp;called amyloid (&nbsp;cutaneous&nbsp;amyloidosis. How often this occurs is not known).&nbsp;Insulin&nbsp;may&nbsp;not work as well if you inject in an area with lumps or in a thickened or shrunken area.&nbsp;Change the injection site for each&nbsp;injection&nbsp;to prevent these skin changes.<\/p>\n\n\n\n<p><strong>b) List of other&nbsp;side&nbsp;effects<\/strong><\/p>\n\n\n\n<p><strong>Uncommon&nbsp;side effects&nbsp;are<\/strong><\/p>\n\n\n\n<p>May affect less than 1 in 100 users.<\/p>\n\n\n\n<p><strong>Signs of allergy:<\/strong>\u00a0Local allergic reactions (pain,\u00a0redness,\u00a0hives,\u00a0inflammation, bruising, swelling, and\u00a0itching\u00a0) may occur at the injection site.\u00a0These symptoms usually go away after taking your\u00a0insulin\u00a0for a few weeks.\u00a0If they do not disappear or spread throughout the body, talk to a doctor immediately.\u00a0See also Severe allergic reactions above.<\/p>\n\n\n\n<p><strong>Vision problems:<\/strong>&nbsp;At the beginning of insulin treatment, visual disturbances may occur, but these are usually temporary.<\/p>\n\n\n\n<p><strong>Swollen joints:<\/strong>\u00a0When you start taking\u00a0insulin, your body may bind water, causing you to swell around the ankles and other joints.\u00a0This usually goes away soon, otherwise, you should talk to a doctor.<\/p>\n\n\n\n<p><strong>Diabetic\u00a0retinopathy\u00a0<\/strong>(an eye disease associated with\u00a0diabetes\u00a0and can lead to vision loss): If you have diabetic\u00a0retinopathy, it can worsen if your blood sugar level improves very quickly.\u00a0Ask your doctor about this.<\/p>\n\n\n\n<p><strong>Rare&nbsp;side&nbsp;effects<\/strong><\/p>\n\n\n\n<p>May affect less than 1 in 1,000 users.<\/p>\n\n\n\n<p><strong>Painful&nbsp;neuropathy<\/strong>&nbsp;(pain due to nerve damage): If your blood sugar level improves very quickly, you may get nerve-related pain.&nbsp;This is called&nbsp;acute&nbsp;painful&nbsp;neuropathy&nbsp;and is usually transient.<\/p>\n\n\n\n<p><strong>c) Problems with&nbsp;diabetes<\/strong><\/p>\n\n\n\n<p><strong>High blood sugar (hyperglycemia)<\/strong><\/p>\n\n\n\n<p>High blood sugar can occur if you:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>have not injected enough&nbsp;insulin&nbsp;.<\/li><li>forget to take your&nbsp;insulin&nbsp;or stop taking&nbsp;insulin&nbsp;.<\/li><li>repeatedly take less&nbsp;insulin&nbsp;than you need.<\/li><li>gets an&nbsp;infection&nbsp;and \/ or fever.<\/li><li>eat more than usual.<\/li><li>exercise less than usual.<\/li><\/ul>\n\n\n\n<p>High blood sugar warning signs:<\/p>\n\n\n\n<p>The warning signals appear gradually.&nbsp;They manifest as: increased urine output;&nbsp;thirst;&nbsp;loss of appetite;&nbsp;feeling sick (nausea or vomiting);&nbsp;drowsiness or fatigue;&nbsp;redness;&nbsp;dry skin;&nbsp;dry mouth&nbsp;and a breath that smells of fruit (acetone).<\/p>\n\n\n\n<p>What should I do if I get high blood sugar:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>If you get any of the above warning signs: check your blood sugar, do a ketone test on your urine if possible and then contact a doctor immediately.<\/li><li>The symptoms can be a sign of a very serious condition called diabetic&nbsp;ketoacidosis&nbsp;(accumulation of acid in the blood when the body breaks down fat instead of sugar).&nbsp;If left untreated, it can lead to diabetic coma and eventually death.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">How to store NovoRapid<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the label and carton of the vial after &#8220;EXP&#8221;.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>Keep the vial in the outer carton.&nbsp;Sensitive to light.<\/p>\n\n\n\n<p><strong>Unopened packaging:<\/strong>\u00a0Store in a refrigerator from 2 \u00b0 C to 8 \u00b0 C.\u00a0Do not store it near the heat sink.\u00a0Do not freeze.<\/p>\n\n\n\n<p><strong>During use or included as a reserve:<\/strong>&nbsp;Store for a maximum of 4 weeks.&nbsp;Do not store above 30 \u00b0 C.&nbsp;Do not refrigerate or freeze.<\/p>\n\n\n\n<p>Discard the injection needle after each\u00a0injection.<\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the pack and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is&nbsp;insulin&nbsp;aspart.&nbsp;Each ml contains 100 units of&nbsp;insulin&nbsp;aspart.&nbsp;Each&nbsp;vial&nbsp;contains 1,000 units of&nbsp;insulin&nbsp;aspart in 10 ml of&nbsp;solution for injection&nbsp;.<\/li><li>The other ingredients are&nbsp;glycerol&nbsp;, phenol, metacresol, zinc chloride, disodium phosphate dihydrate, sodium chloride,&nbsp;hydrochloric acid&nbsp;, sodium hydroxide and water for injections.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and contents of the pack<\/h2>\n\n\n\n<p>NovoRapid is in the form of a\u00a0solution for injection.<\/p>\n\n\n\n<p>Pack sizes: 1 or 5 10 ml vials or multiple packs of 5 x (1 x 10 ml) vials.<\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<p>The solution is clear and colorless.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p>Novo Nordisk A \/ S, Novo All\u00e9, DK-2880 Bagsv\u00e6rd, Denmark<\/p>\n","protected":false},"excerpt":{"rendered":"<p>NovoRapid is a modern insulin (insulin analogue) that is fast-acting. Modern insulins are improved versions of human insulin .<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,15581],"tags":[19214,19210,19213,19215,19219,19218,19212,19211,19216,19217],"class_list":["post-19240","post","type-post","status-publish","format-standard","hentry","category-medicines","category-n","tag-benefits-of-insulin-aspart-vial","tag-insulin-aspart-vial","tag-insulin-aspart-vial-side-effects","tag-novorapid","tag-novorapid-insulin","tag-novorapid-side-effects","tag-what-insulin-aspart-vial-is-used-for","tag-what-is-insulin-aspart-vial","tag-what-is-novorapid","tag-what-novorapid-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/19240","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=19240"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/19240\/revisions"}],"predecessor-version":[{"id":19273,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/19240\/revisions\/19273"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=19240"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=19240"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=19240"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}