{"id":19236,"date":"2022-03-04T16:25:27","date_gmt":"2022-03-04T16:25:27","guid":{"rendered":"https:\/\/zeepedia.com\/?p=19236"},"modified":"2022-03-07T16:23:32","modified_gmt":"2022-03-07T16:23:32","slug":"novonorm","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/novonorm\/","title":{"rendered":"NovoNorm &#8211; Repaglinide uses, dose and side effects"},"content":{"rendered":"\n<p>Tablet 0.5 mg, 1 mg, 2 mg<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What NovoNorm is and what it is used for<\/h2>\n\n\n\n<p>NovoNorm\u00a0<em>contains repaglinide<\/em>\u00a0and is an\u00a0<em>oral tablet for the treatment of\u00a0diabetes<\/em>.\u00a0NovoNorm helps your\u00a0pancreas\u00a0to produce more\u00a0insulin\u00a0and lower your blood sugar (\u00a0glucose\u00a0).<\/p>\n\n\n\n<p><strong>Type 2&nbsp;diabetes<\/strong>&nbsp;is a disease in which the pancreas does not produce enough&nbsp;insulin&nbsp;to control the level of sugar in your blood or where your body does not respond normally to the&nbsp;insulin&nbsp;it produces.<\/p>\n\n\n\n<p>NovoNorm is used to control type 2\u00a0diabetes\u00a0in adults as a supplement to diet and exercise.\u00a0Treatment is usually started if diet, exercise and weight loss alone are not enough to control (or lower) your blood sugar.\u00a0NovoNorm can also be given with\u00a0metformin, another diabetes medicine.<\/p>\n\n\n\n<p>NovoNorm lowers blood sugar, which helps prevent complications of your\u00a0diabetes.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before you take NovoNorm<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not take NovoNorm<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are&nbsp;<strong>allergic<\/strong>&nbsp;to repaglinide or any of the other ingredients of this medicine (listed in section 6).<\/li><li>if you have&nbsp;<strong>type 1&nbsp;diabetes<\/strong>&nbsp;.<\/li><li>if the acid level in the blood is elevated&nbsp;<strong>(&nbsp;<\/strong><strong>diabetic ketoacidosis&nbsp;<\/strong><strong>).<\/strong><\/li><li>if you have&nbsp;<strong>severe liver disease.<\/strong><\/li><li>if you are taking&nbsp;<strong>gemfibrozil<\/strong>&nbsp;(for the treatment of high blood fats).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor before taking NovoNorm:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you have&nbsp;<strong>liver problems<\/strong>&nbsp;.&nbsp;NovoNorm is not recommended for patients with moderate liver disease.&nbsp;NovoNorm should not be taken if you have severe liver disease (see&nbsp;<em>Do not take NovoNorm<\/em>&nbsp;).<\/li><li>if you have&nbsp;<strong>kidney problems<\/strong>&nbsp;.&nbsp;NovoNorm should then be used with caution.<\/li><li>if you are going to have&nbsp;<strong>major surgery<\/strong>&nbsp;or have recently had a&nbsp;<strong>serious illness<\/strong>&nbsp;or&nbsp;<strong>infection<\/strong>&nbsp;.&nbsp;In such cases, diabetes control may be insufficient.<\/li><li>if you are&nbsp;<strong>under 18<\/strong>&nbsp;or&nbsp;<strong>over 75 years of age<\/strong>&nbsp;.&nbsp;NovoNorm can then not be recommended, as studies in these age groups are lacking.<\/li><\/ul>\n\n\n\n<p><strong>Talk to your doctor<\/strong>&nbsp;if any of the above apply to you.&nbsp;Then you may not be treated with NovoNorm, but your doctor will advise you.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children and young people<\/h2>\n\n\n\n<p>Do not take this medicine if you are under 18 years of age.<\/p>\n\n\n\n<p><strong>If you get an insulin sensation (low blood sugar)<\/strong><\/p>\n\n\n\n<p>You get insulin sensation (&nbsp;hypoglycaemia&nbsp;) if your blood sugar gets too low.&nbsp;It could happen:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you take too much NovoNorm<\/li><li>if you exercise more than usual<\/li><li>if you are taking other medicines or have kidney or liver problems (see other sections under&nbsp;<em>2. What you need to know before taking NovoNorm<\/em>&nbsp;).<\/li><\/ul>\n\n\n\n<p><strong>The warning signs of low blood sugar<\/strong>&nbsp;can come on suddenly and manifest themselves as: cold sweat;&nbsp;cold and pale skin;&nbsp;headache;&nbsp;palpitation;&nbsp;nausea;&nbsp;strong hunger;&nbsp;temporary vision changes;&nbsp;drowsiness;&nbsp;unusual fatigue and weakness;&nbsp;nervousness or tremors;&nbsp;feelings of anxiety;&nbsp;confusion;&nbsp;concentration difficulties.<\/p>\n\n\n\n<p><strong>If your blood sugar is low or you get an insulin sensation:<\/strong>\u00a0eat glucose tablets or a snack or a drink that contains a lot of sugar and then rest.<\/p>\n\n\n\n<p><strong>When the symptoms of\u00a0hypoglycaemia\u00a0have disappeared or your blood sugar level has stabilized<\/strong>, you can continue treatment with NovoNorm.<\/p>\n\n\n\n<p><strong>Tell people around you that you have\u00a0diabetes\u00a0and that if you become unconscious<\/strong>, they should put you on the sidelines and get medical attention immediately.\u00a0They must not give you anything to eat or drink.\u00a0Then there is a risk that you will suffocate.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>If severe insulin sensitivity<\/strong>&nbsp;is not treated, it can cause brain damage (temporary or permanent) and even death.<\/li><li><strong>If you get an insulin sensation<\/strong>&nbsp;and lose consciousness, or if you get a lot of insulin sensations, talk to your doctor.&nbsp;Dose&nbsp;a NovoNorm, diet or exercise may need to be adjusted.<\/li><\/ul>\n\n\n\n<p><strong>If your blood sugar gets too high<\/strong><\/p>\n\n\n\n<p>Your blood sugar may become too high (this is called&nbsp;hyperglycaemia&nbsp;).&nbsp;It can have the following causes:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>You have taken too small a&nbsp;dose&nbsp;of NovoNorm<\/li><li>You have an&nbsp;infection&nbsp;or fever<\/li><li>You have eaten more than usual<\/li><li>You have exercised less than usual.<\/li><\/ul>\n\n\n\n<p><strong>The warning signs of high blood sugar<\/strong>\u00a0gradually appear.\u00a0They manifest as: increased urine output;\u00a0thirst;\u00a0dry skin and\u00a0dry mouth.\u00a0Talk to your doctor.\u00a0Dose\u00a0a NovoNorm, diet or exercise may need to be adjusted.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and NovoNorm<\/h2>\n\n\n\n<p><strong>Tell your doctor<\/strong>&nbsp;or pharmacist if you are taking, have recently taken or might take any other medicines.<\/p>\n\n\n\n<p>You can take NovoNorm with\u00a0metformin, another diabetes medicine if your doctor tells you to.\u00a0If you are taking gemfibrozil (for the treatment of high blood fats), you should not take NovoNorm.<\/p>\n\n\n\n<p>Your body may react differently to NovoNorm if you take other medicines, especially these:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>MAO inhibitors&nbsp;(used to treat depression)<\/li><li>Beta-receptor blockers (used to treat high&nbsp;blood pressure&nbsp;or heart disease)<\/li><li>ACE inhibitors&nbsp;(used to treat heart disease)<\/li><li>Salicylates (included with some painkillers)<\/li><li>Octreotide (used to treat cancer)<\/li><li>Non-steroidal anti-inflammatory drugs (&nbsp;NSAIDs&nbsp;) (painkillers)<\/li><li>Steroids&nbsp;(anabolic&nbsp;steroids&nbsp;and&nbsp;corticosteroids&nbsp;&#8211; used in&nbsp;anemia&nbsp;or treatment of&nbsp;inflammation&nbsp;)<\/li><li>Oral contraceptives (&nbsp;birth control pills&nbsp;)<\/li><li>Thiazides&nbsp;(&nbsp;diuretics&nbsp;or diuretics)<\/li><li>Danazol (used to treat breast cysts and endometrial tissue outside the uterus, called&nbsp;endometriosis&nbsp;)<\/li><li>Thyroid drugs (used to treat low levels of thyroid hormones)<\/li><li>Adrenergic agents (used to treat&nbsp;asthma&nbsp;)<\/li><li>Clarithromycin, trimethoprim, rifampicin (&nbsp;antibiotics&nbsp;)<\/li><li>Itraconazole,&nbsp;ketoconazole&nbsp;(antifungal)<\/li><li>Gemfibrozil (used to treat high blood fats)<\/li><li>Ciclosporin (used to&nbsp;inhibit&nbsp;the immune system)<\/li><li>Deferasirox (used to remove excess iron from the body)<\/li><li>Clopidogrel (prevents the formation of blood clots)<\/li><li>Phenytoin&nbsp;, carbamazepine, phenobarbital (used to treat&nbsp;epilepsy&nbsp;)<\/li><li>St. John&#8217;s wort&nbsp;(herbal medicine).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">NovoNorm with alcohol<\/h2>\n\n\n\n<p>Alcohol may alter NovoNorm&#8217;s ability to lower blood sugar.&nbsp;Pay attention to signs of insulin sensation.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant or are planning to have a baby, ask your doctor for advice before using this medicine.<\/p>\n\n\n\n<p>You should not take NovoNorm if you are pregnant or planning to become pregnant.<\/p>\n\n\n\n<p>You should not take NovoNorm if you are breastfeeding.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Your ability to drive or use machines may be affected if your blood sugar is too high or too low.&nbsp;Remember that you can&nbsp;put&nbsp;yourself and others at risk.&nbsp;Talk to your doctor if you can drive if you:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>often have insulin sensations<\/li><li>receive few or no warning signs of low blood sugar.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">How to take NovoNorm<\/h2>\n\n\n\n<p>Always take this medicine exactly as your doctor has told you.\u00a0Consult a doctor if you are unsure.\u00a0Your doctor will determine your\u00a0dose.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>The usual starting dose<\/strong>&nbsp;is 0.5 mg before each main meal.&nbsp;Swallow the tablets with a glass of waterimmediately before or up to 30 minutes before each main meal.<\/li><li>Your doctor may increase the&nbsp;dose&nbsp;to one up to 4 mg immediately before or up to 30 minutes before each main meal.&nbsp;The maximum recommended daily&nbsp;dose&nbsp;is 16 mg.<\/li><\/ul>\n\n\n\n<p>Do not take more NovoNorm than your doctor has prescribed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you take more NovoNorm than you should<\/h2>\n\n\n\n<p>If you take too many tablets, your blood sugar may become too low and lead to insulin sensation.&nbsp;See&nbsp;<em>If you get an insulin sensation<\/em>&nbsp;for more information on what this is and how it is treated.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to take NovoNorm<\/h2>\n\n\n\n<p>If you miss a\u00a0dose, take the next\u00a0dose\u00a0as usual &#8211; do not take a double\u00a0dose.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop taking NovoNorm<\/h2>\n\n\n\n<p>Keep in mind that you will not get the desired effect if you stop taking NovoNorm.&nbsp;Your&nbsp;diabetes&nbsp;may worsen.&nbsp;If your treatment needs to be changed, always consult your doctor first.<\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p>Low blood sugar (&nbsp;hypoglycaemia&nbsp;)<\/p>\n\n\n\n<p>The most common\u00a0side effect\u00a0is low blood sugar, which may occur in up to 1 in 10 patients (see\u00a0<em>If you get an insulin sensation<\/em>\u00a0in section 2).\u00a0Reactions to low blood sugar are generally mild\/moderate but can sometimes develop into hypoglycaemic unconsciousness or\u00a0coma.\u00a0If this happens, seek medical attention immediately.<\/p>\n\n\n\n<p>Allergy<\/p>\n\n\n\n<p>Allergies\u00a0are very rare (may affect up to 1 in 10,000 patients).\u00a0Symptoms such as swelling, difficulty breathing, palpitations, dizziness and sweating may be signs of\u00a0an anaphylactic reaction.\u00a0Contact a doctor immediately.<\/p>\n\n\n\n<p>Other&nbsp;side effects&nbsp;ar<\/p>\n\n\n\n<p><strong>Common<\/strong>&nbsp;(may affect up to 1 in 10 people)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Abdominal pain<\/li><li>Diarrhea.<\/li><\/ul>\n\n\n\n<p><strong>Rare<\/strong>&nbsp;(may affect up to 1 in 1,000 people)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Acute&nbsp;coronary heart disease (does not need to be related to the drug).<\/li><\/ul>\n\n\n\n<p><strong>Very rare<\/strong>&nbsp;(may affect up to 1 in 10,000 people)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Vomiting<\/li><li>Constipation<\/li><li>Visual disturbances<\/li><li>Severe liver problems, abnormal liver function such as increase in liver enzymes in your blood.<\/li><\/ul>\n\n\n\n<p><strong>Unknown frequency<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Hypersensitivity (such as rash, itchy skin, redness of the skin, swelling of the skin)<\/li><li>Nausea.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">How to store NovoNorm<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the carton and blister after EXP.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>Store the tablets in the original package.&nbsp;Moisture sensitive.<\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the pack and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<p>&#8211; The active substance is repaglinide.<\/p>\n\n\n\n<p>The other ingredients are microcrystalline cellulose (E460), anhydrous calcium hydrogen phosphate, maize starch, potassium polarizing, povidone (polyvidone),\u00a0glycerol\u00a085%, magnesium stearate, meglumine, poloxamer, yellow iron oxide (E172) only in 1 mg tablets (E17) only tablets and red iron 2 mg tablets.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and contents of the pack<\/h2>\n\n\n\n<p>NovoNorm tablets are round and convex and engraved with the Novo Nordisk logo (Apis bull).\u00a0The strengths are 0.5 mg, 1 mg and 2 mg.\u00a0The 0.5 mg tablets are white, the 1 mg tablets are yellow and the 2 mg tablets are peach-coloured.\u00a0The tablets are available in blister packs in four different pack sizes containing 30, 90, 120 or 270 tablets.<\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p>Novo Nordisk A \/ S<\/p>\n\n\n\n<p>Novo All\u00e9, DK-2880 Bagsv\u00e6rd, Denmark.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>NovoNorm contains repaglinide and is an oral tablet for the treatment of diabetes . NovoNorm helps your pancreas to produce more insulin and lower your blood sugar ( glucose ).<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,15581],"tags":[19235,19230,19231,19234,19225,19229,19228,19232,19226,19233,19227],"class_list":["post-19236","post","type-post","status-publish","format-standard","hentry","category-medicines","category-n","tag-benefits-of-novonorm","tag-benefits-of-repaglinide","tag-novonorm","tag-novonorm-side-effects","tag-repaglinide","tag-repaglinide-side-effects","tag-repaglinide-tablet","tag-what-is-novonorm","tag-what-is-repaglinide","tag-what-novonorm-is-used-for","tag-what-repaglinide-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/19236","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=19236"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/19236\/revisions"}],"predecessor-version":[{"id":19275,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/19236\/revisions\/19275"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=19236"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=19236"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=19236"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}