{"id":19114,"date":"2022-03-03T07:42:03","date_gmt":"2022-03-03T07:42:03","guid":{"rendered":"https:\/\/zeepedia.com\/?p=19114"},"modified":"2022-03-03T11:03:56","modified_gmt":"2022-03-03T11:03:56","slug":"noradrenaline-aguettant","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/noradrenaline-aguettant\/","title":{"rendered":"Noradrenaline Aguettant &#8211; Noradrenaline uses, dose and side effects"},"content":{"rendered":"\n<p>0.08 mg \/ ml solution for infusion<br>noradrenaline<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Noradrenaline Aguettant is and what it is used for<\/h2>\n\n\n\n<p>The drug contains the active substance\u00a0norepinephrine, which causes the blood vessels to constrict (\u00a0vasoconstriction\u00a0).<\/p>\n\n\n\n<p>The drug is only intended for adults weighing more than 50 kg.\u00a0The drug is used for the treatment of\u00a0acute\u00a0low\u00a0blood pressure\u00a0in emergencies that require immediate normalization of\u00a0blood pressure, and where rising noradrenaline doses are necessary.<\/p>\n\n\n\n<p>Noradrenaline\u00a0contained in\u00a0Noradrenaline\u00a0Aguettant may also be approved for the treatment of other conditions not mentioned in this product information.\u00a0Ask your doctor, pharmacist, or other healthcare professionals if you have any further questions, and always follow their instructions.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before you use Noradrenaline Aguettant<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Noradrenaline Aguettant<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>administered via&nbsp;peripheral&nbsp;cannula and \/ or peripheral vein<\/li><li>if you are allergic to&nbsp;norepinephrine&nbsp;or any of the other ingredients of this medicine (listed in section 6).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor or nurse before using&nbsp;Noradrenaline&nbsp;Aguettant<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you have severe left ventricular dysfunction (a heart defect)<\/li><li>if you have recently had a heart attack<\/li><li>if you have an irregular heartbeat (your heart beats too fast, too slow or irregularly)<\/li><li>if you have&nbsp;hyperthyroidism&nbsp;(your&nbsp;thyroid gland&nbsp;is overactive)<\/li><li>if you have&nbsp;diabetes<\/li><li>if you have low&nbsp;blood pressure&nbsp;caused by low blood volume (&nbsp;hypovolemia&nbsp;)<\/li><li>if you have angina or a blockage of blood vessels in the arms \/ legs or abdomen (&nbsp;acute&nbsp;difficulty for the blood to circulate normally).<\/li><\/ul>\n\n\n\n<p>During\u00a0infusion\u00a0one of\u00a0norepinephrine, your doctor will continuously monitor your\u00a0blood pressure, your heart rate (heart rate), and the infusion site.<\/p>\n\n\n\n<p>In cases where it is necessary to give&nbsp;norepinephrine&nbsp;at the same time as a blood or plasma transfusion, it will later be given as a separate drip.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children and young people<\/h2>\n\n\n\n<p>The drug is intended for adults only.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Noradrenaline Aguettant<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines, such as:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>certain anesthetic gas (halogen)<\/li><li>certain antidepressants (imipramine, serotonergic-adrenergic agents such as&nbsp;venlafaxine&nbsp;or duloxetine, monoamine oxidase inhibitors such as moclobemide or phenelzine)<\/li><li>linezolid (an&nbsp;antibiotic&nbsp;)<\/li><li>methylene blue (antidote to methemoglobinemia).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, talk to your doctor or nurse before using this medicine.\u00a0If you are pregnant, your doctor will decide if you should receive the medicine, as\u00a0norepinephrine\u00a0can harm the fetus.<\/p>\n\n\n\n<p>There is no information on the use of\u00a0norepinephrine\u00a0during breastfeeding.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Noradrenaline Aguettant contains sodium<\/h2>\n\n\n\n<p>This medicine contains 177.3 mg\u00a0sodium\u00a0(the main ingredient in table salt\/table salt) per 50 ml\u00a0vial.\u00a0This corresponds to 8.9% of the highest recommended daily intake of\u00a0sodium\u00a0for adults.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to use Noradrenaline Aguettant<\/h2>\n\n\n\n<p>This medicine is given in a hospital by a doctor or nurse.<\/p>\n\n\n\n<p>This medicine is given by&nbsp;intravenous&nbsp;infusion&nbsp;(into a vein) and only through a central venous catheter.<\/p>\n\n\n\n<p>The dose&nbsp;of one of these drugs depends on your condition.&nbsp;Your doctor will decide which&nbsp;dose&nbsp;is best for you.<\/p>\n\n\n\n<p>This medicine should not be used to start treatment with vasoconstrictors (vasopressor treatment) but may be considered for patients who are already receiving&nbsp;norepinephrine&nbsp;and who need increasing&nbsp;doses&nbsp;(clinically confirmed).<\/p>\n\n\n\n<p><strong>If you use more\u00a0Noradrenaline\u00a0Aguettant then you should<\/strong><\/p>\n\n\n\n<p>In case of overdose, the following symptoms may be observed: contraction of\u00a0vessels\u00a0in the skin (blood vessels become narrower), pressure ulcers (skin ulcers),\u00a0shock\u00a0(\u00a0circulatory failure\u00a0), and high\u00a0blood pressure.<\/p>\n\n\n\n<p>If you get&nbsp;any side effects&nbsp;associated with an overdose, contact your doctor immediately.&nbsp;Dose&nbsp;one should be reduced, if possible.<\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or nurse.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p>The following&nbsp;side effects&nbsp;have been reported:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>anxiety<\/li><li>headaches, tremors<\/li><li>acute&nbsp;glaucoma&nbsp;(increased pressure in the eye)<\/li><li>tachycardia&nbsp;(fast heartbeat),&nbsp;bradycardia&nbsp;(slow heartbeat),&nbsp;arrhythmia&nbsp;(irregular heartbeat), palpitations, heavier heart muscle contractions,&nbsp;acute&nbsp;heart failure<\/li><li>arterial&nbsp;hypertension&nbsp;(high&nbsp;blood pressure&nbsp;) and tissue hypoxia (decreased oxygen supply to certain organs);&nbsp;cold and pallor in limbs and face, painful and cold hands \/ feet (cold sores),<\/li><li>difficulty breathing,&nbsp;dyspnoea&nbsp;(shortness of breath)<\/li><li>vomiting<\/li><li>urinary retention&nbsp;(difficulty emptying the bladder)<\/li><li>local: possible irritation and&nbsp;necrosis&nbsp;(cell damage, causing cell death in&nbsp;tissue&nbsp;) in the injection site.<\/li><\/ul>\n\n\n\n<p>Continuous&nbsp;administration&nbsp;of&nbsp;Noradrenaline&nbsp;Aguettant (to maintain&nbsp;blood pressure&nbsp;in the absence of blood volume replacement) may cause the following symptoms:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>severe&nbsp;peripheral&nbsp;and internal vasoconstriction (&nbsp;vasoconstriction&nbsp;)<\/li><li>decreased blood flow to the kidneys<\/li><li>decreased urine production<\/li><li>hypoxia&nbsp;(too low oxygenation)<\/li><li>increased serum lactate&nbsp;levels&nbsp;.<\/li><\/ul>\n\n\n\n<p>In case of hypersensitivity or overdose, the following\u00a0side effects\u00a0may occur more frequently:\u00a0arterial\u00a0hypertension\u00a0(high\u00a0blood pressure\u00a0),\u00a0photophobia\u00a0(eyes abnormally sensitive to light), retrosternal pain (pain behind the sternum),\u00a0pharyngeal\u00a0pain (sore throat), pallor, intense sweating, and vomiting.<\/p>\n\n\n\n<p><strong>Reporting of&nbsp;side effects&nbsp;ar<\/strong><\/p>\n\n\n\n<p>If you get\u00a0any side effects, talk to your doctor or nurse.\u00a0This also applies to\u00a0side effects\u00a0that are not mentioned in this information.\u00a0You can also report\u00a0side effects\u00a0directly (see address below).\u00a0By reporting\u00a0side effects, you can help increase drug safety information.<\/p>\n\n\n\n<p>The Medical Products Agency<\/p>\n\n\n\n<p>Box 26<\/p>\n\n\n\n<p>751 03 Uppsala<\/p>\n\n\n\n<p><a href=\"https:\/\/www.lakemedelsverket.se\/sv\" target=\"_blank\" rel=\"noreferrer noopener\">www.lakemedelsverket.se<\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Noradrenaline Aguettant<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the vial label and the carton after EXP.\u00a0The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>After the first opening, the product should be used immediately.<\/p>\n\n\n\n<p>Do not store above 25 \u00b0 C.&nbsp;Keep the vial in the outer carton.&nbsp;Sensitive to light.<\/p>\n\n\n\n<p>Do not use this medicine if the solution is darker than slightly yellowish or pink in color or if it contains precipitates.<\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the pack and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is&nbsp;norepinephrine&nbsp;.&nbsp;Each ml of solution contains 0.08 mg of&nbsp;noradrenaline&nbsp;(as noradrenaline tartrate).&nbsp;Each 50 ml&nbsp;vial&nbsp;contains 4 mg of&nbsp;noradrenaline&nbsp;(as noradrenaline tartrate).<\/li><li>The other ingredients are sodium chloride, disodium edetate,&nbsp;hydrochloric acid&nbsp;or sodium hydroxide (for&nbsp;pH&nbsp;adjustment) and water for injections.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and contents of the pack<\/h2>\n\n\n\n<p>Clear, colorless, or slightly yellowish\u00a0infusion\u00a0solution in a clear\u00a0glass\u00a0vial.\u00a0Each\u00a0vial\u00a0contains 50 ml of solution for\u00a0infusion.\u00a0Pack sizes: 1, 10, and 25 vials.<\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p>AGUETTANT Laboratory<\/p>\n\n\n\n<p>1, rue Alexander Fleming<\/p>\n\n\n\n<p>69007 LYON<\/p>\n\n\n\n<p>FRAN<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The drug contains the active substance norepinephrine , which causes the blood vessels to constrict ( vasoconstriction ).<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,15581],"tags":[19032,19038,19028,19034,19037,19031,19029,19035,19036,19030],"class_list":["post-19114","post","type-post","status-publish","format-standard","hentry","category-medicines","category-n","tag-benefits-of-noradrenaline","tag-benefits-of-noradrenaline-aguettant","tag-noradrenaline","tag-noradrenaline-aguettant","tag-noradrenaline-aguettant-side-effects","tag-noradrenaline-side-effects","tag-what-is-noradrenaline","tag-what-is-noradrenaline-aguettant","tag-what-noradrenaline-aguettant-is-used-for","tag-what-noradrenaline-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/19114","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=19114"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/19114\/revisions"}],"predecessor-version":[{"id":19150,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/19114\/revisions\/19150"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=19114"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=19114"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=19114"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}