{"id":19041,"date":"2022-03-01T16:34:38","date_gmt":"2022-03-01T16:34:38","guid":{"rendered":"https:\/\/zeepedia.com\/?p=19041"},"modified":"2022-03-02T14:24:28","modified_gmt":"2022-03-02T14:24:28","slug":"niontix","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/niontix\/","title":{"rendered":"Niontix &#8211; Nitric oxide (medical nitrous oxide) uses, dose and side effects"},"content":{"rendered":"\n<p>100%,&nbsp;medical gas, liquid<br>Nitric oxide (medical nitrous oxide)<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Niontix is \u200b\u200band what it is used for<\/h2>\n\n\n\n<p>Niontix is \u200b\u200ba gas (nitrous oxide, nitrous oxide) used for inhalation.\u00a0It has a faintly sweet taste and smell and is colorless.\u00a0It is provided in a gas bottle that has a valve to control the outflow of gas.\u00a0The gas bottle contains pure Niontix under such a high pressure that the gas is liquid.<\/p>\n\n\n\n<p><strong>The effects of Niontix<\/strong><\/p>\n\n\n\n<p>Niontix provides anesthetic effects &#8211; (sleeping effects) and will make you relaxed and tired when inhaled and it can make you fall asleep &#8211; asleep.\u00a0Niontix has an analgesic effect, reduces the pain experience, and raises the pain threshold.\u00a0Niontix also provides a relaxing and slightly soothing effect.\u00a0These effects are caused by nitrous oxide affecting neurotransmitters in your nervous system.<\/p>\n\n\n\n<p><strong>What is Niontix used for?<\/strong><\/p>\n\n\n\n<p>Niontix is \u200b\u200bused in all age groups as part of the anesthesia during\u00a0surgery, or when rapid onset and rapidly subsiding analgesic \/ calming effects are desired and when the\u00a0intensity\u00a0one in the pain being treated is mild to moderate and short-lived.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before you use Niontix<\/h2>\n\n\n\n<p>You will only receive Niontix when you are in hospital or doctor&#8217;s surgery and under the supervision of a healthcare professional.&nbsp;Tell your healthcare provider if you have any other illnesses.<\/p>\n\n\n\n<p><strong>Do not use Niontix:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Inhalation of nitrous oxide (Niontix), can cause gas bubbles in the body and cause gas-filled spaces to expand and thus cause damage.&nbsp;Therefore, do not use Niontix if you:<ul><li>have air in the lung or heart sac (eg due to illness or injury), have a severe type of&nbsp;pulmonary emphysema&nbsp;(eg due to smoking), air or gas-filled bubbles in the body.<\/li><li>have recently dived with diving equipment and thus may be at risk of diving disease.<\/li><li>has recently been treated in a heart \/ lung machine.<\/li><li>has recently suffered a severe head injury.<\/li><li>If you have recently been treated with an&nbsp;injection&nbsp;of gas into the eyeball, due to an eye disease.&nbsp;Increased pressure in the eye can cause blindness.<\/li><li>If you have severe stomach problems.<\/li><\/ul><\/li><\/ul>\n\n\n\n<ul class=\"wp-block-list\"><li>If you have&nbsp;heart failure&nbsp;or severe heart function (eg after heart surgery).&nbsp;Nitrous oxide can cause a further deterioration of heart function.<\/li><li>If you have increased pressure in the brain, which can make you confused or affect your level of consciousness.&nbsp;The nitrous oxide can further increase the pressure.<\/li><li>If your level of awareness or ability to cooperate and follow instructions decreases when you receive nitrous oxide.&nbsp;Nitrous oxide can&nbsp;inhibit&nbsp;protective reflexes.<\/li><li>If you have a diagnosed but untreated&nbsp;vitamin&nbsp;B&nbsp;<sub>12<\/sub>&nbsp;deficiency or <a href=\"https:\/\/zeepedia.com\/medical\/medicines\/triobe\/\">folic acid<\/a> deficiency or have a genetic disorder in the enzyme systems involved in the metabolism of these&nbsp;vitamins&nbsp;, as the use of nitrous oxide may further aggravate the deficiency.<\/li><li>In case of injury to the jaw and face, then the use of a face mask can involve difficulties or risks.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor or nurse before using Niontix if you have any of the following symptoms\/symptoms\/conditions.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Affected cardiac function<\/strong>Because the slightly relaxing effect that nitrous oxide has on the heart muscle can further impair heart function.<\/li><li><strong>Ear problems<\/strong>such as ear inflammation, as Niontix may increase the pressure in the middle ear<\/li><li><strong>Have or have had drug or drug abuse<\/strong>&nbsp;, as there is then a higher risk of developing dependence on nitrous oxide during repeated use.&nbsp;Your doctor will decide if treatment with Niontix is \u200b\u200bappropriate in your case.<\/li><li><strong>Vitamin deficiency<\/strong>If you&nbsp;<em>suspect<\/em>&nbsp;you have&nbsp;vitamin&nbsp;B&nbsp;<sub>12<\/sub>&nbsp;deficiency or folic acid deficiency, then the use of Niontix may aggravate the symptoms caused by&nbsp;vitamin&nbsp;B&nbsp;<sub>12<\/sub>&nbsp;deficiency and folic acid.<\/li><\/ul>\n\n\n\n<p>Your doctor will assess whether it is appropriate to use Niontix.<\/p>\n\n\n\n<p>Repeated or prolonged use of nitrous oxide can increase the risk of&nbsp;vitamin&nbsp;B&nbsp;<sub>12<\/sub>&nbsp;deficiency, which can lead to damage to the&nbsp;bone marrow&nbsp;or the nervous system.&nbsp;Your doctor may perform blood tests before and after treatment, to assess the consequences of any&nbsp;vitamin&nbsp;B&nbsp;<sub>12<\/sub>&nbsp;deficiency.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Niontix<\/h2>\n\n\n\n<p>Tell your doctor or nurse if you are taking, have recently taken, or might take any other medicines.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Methotrexate for the treatment of e.g.&nbsp;rheumatoid arthritis&nbsp;.&nbsp;Using Niontix with methotrexate may affect your blood count.<\/li><li>If you are taking other medicines that affect the brain or brain functions e.g.&nbsp;benzodiazepines (sedatives) or morphine-like medicines, tell your doctor.&nbsp;Niontix may potentiate the effects of these medicines.&nbsp;Niontix in combination with other medicines that affect the&nbsp;central nervous system&nbsp;increases the risk of&nbsp;side effects&nbsp;from these medicines&nbsp;<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, breastfeeding and fertility<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or nurse for advice before taking this medicine.<\/p>\n\n\n\n<p>Niontix can be used during pregnancy if your doctor thinks it is medically necessary.\u00a0It can also be used during childbirth.\u00a0If Niontix is \u200b\u200bused near the time of delivery, your baby should be monitored for breathing difficulties (\u00a0respiratory depression\u00a0) and other\u00a0side effects.<\/p>\n\n\n\n<p>Nitrous oxide can be used during the breastfeeding period, but should not be used during the actual breastfeeding session.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>If you have only been given Niontix together with medical oxygen, without any other medicines, you should, for safety reasons, avoid driving, using machines, or performing complicated tasks until you are fully recovered (for at least 30 minutes).<\/p>\n\n\n\n<p>Always make sure that your healthcare professional gives you advice when it is safe for you to drive a car.<\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened vigilance.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects.\u00a0Descriptions of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to use Niontix<\/h2>\n\n\n\n<p>Niontix is \u200b\u200balways given in the presence of healthcare professionals who decide what&nbsp;dose&nbsp;you receive.&nbsp;You should always follow the instructions of your healthcare professional when breathing the gas.<\/p>\n\n\n\n<p>At all times you receive Niontix, healthcare professionals should monitor you to ensure that\u00a0inhalation\u00a0is given and used safely.\u00a0After\u00a0inhalation, you will be monitored by a healthcare professional until you have recovered.<\/p>\n\n\n\n<p>You usually breathe Niontix through a face mask or nasal mask.\u00a0Either you breathe yourself &#8211; you &#8220;spontaneously breathe&#8221; or you get help to breathe from a respirator\/ventilator, as in anesthesia.\u00a0It is given as a gas mix with oxygen and the doctor ensures that the oxygen concentration is high enough to avoid oxygen deficiency.<\/p>\n\n\n\n<p>Anesthetic<\/p>\n\n\n\n<p>When anesthetized, Niontix is \u200b\u200bcombined with other anesthetics, and the concentration needed for an anesthetic effect is determined by your doctor.<\/p>\n\n\n\n<p>Pain-relieving and calming effect<\/p>\n\n\n\n<p>When used for an analgesic or sedative effect, rapid onset, and rapid resuscitation, Niontix is \u200b\u200binhaled for the duration of the procedure or for as long as the analgesic effect is desired.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Use for children<\/h2>\n\n\n\n<p>Your doctor will make sure that an appropriate\u00a0dose\u00a0is given and that your child is closely monitored, due to the potential risk of unconsciousness and loss of protective reflexes (eg vomiting reflex) at higher\u00a0doses.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you use more Niontix than you should&nbsp;<\/h2>\n\n\n\n<p>You should always follow the instructions of your healthcare professional when breathing Niontix.\u00a0If you feel that you have been given too much Niontix and have an air hunger (get too little oxygen in your blood) or experience a decrease in consciousness, stop\u00a0inhaling\u00a0one of Niontix and make the staff aware of this.\u00a0Depending on the circumstances, you will be able to breathe ordinary fresh air or you will be given extra oxygen.\u00a0Your oxygen content in the blood will be monitored continuously using a so-called pulse oximeter.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Safety instructions<\/h3>\n\n\n\n<ul class=\"wp-block-list\"><li>Smoking and open fire are strictly prohibited in rooms where nitrous oxide treatment is in progress.<\/li><li>Niontix (medical nitrous oxide) is for medical use only.<\/li><\/ul>\n\n\n\n<p>See also instructions on storage and handling of gas cylinders.&nbsp;(5. How to store Niontix).<\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or nurse.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p><em>Common<\/em>&nbsp;can occur in up to 1 in 10 users:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Dizziness, dizziness,&nbsp;euphoria<\/li><li>Nausea and vomiting<\/li><\/ul>\n\n\n\n<p><em>Uncommon<\/em>&nbsp;may occur in up to 1 in 100 users:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Ears are blocked.&nbsp;This is because Niontix increases the pressure in the middle ear.<\/li><li>Flatulence due to Niontix slowly increasing the volume of gas in the intestines.<\/li><\/ul>\n\n\n\n<p><em>No known frequency<\/em>&nbsp;(can not be calculated from the available data):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Effects on nerve function, numbness and weakness, usually in the legs<\/li><li>Respiratory depression&nbsp;(shallow and slow breathing)<\/li><li>Mental effects such as anxiety and&nbsp;psychosis<\/li><li>The following symptoms occur because Niontix affects the amount of&nbsp;vitamin&nbsp;B&nbsp;<sub>12<\/sub>&nbsp;in the body:<ul><li>Low&nbsp;white blood cell count<\/li><li>A certain type of&nbsp;anemia&nbsp;called megaloblastic&nbsp;anemia&nbsp;.If your doctor suspects&nbsp;vitamin&nbsp;B&nbsp;<sub>12<\/sub>&nbsp;deficiency , you can get&nbsp;vitamin&nbsp;B treatment to minimize the risk of these&nbsp;side effects&nbsp;.<\/li><\/ul><\/li><li>Headache and confusion (after completion of treatment)<\/li><li>Dependent<\/li><li>Cramps<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Niontix<\/h2>\n\n\n\n<p>This medicine does not require any special storage instructions regarding temperature, other than those applicable to gas containers and gas under pressure.<\/p>\n\n\n\n<p>Do not smoke or use open flames in rooms where medical gases are stored.<\/p>\n\n\n\n<p>Store the bottle in a locked and well-ventilated area reserved for medical gases.<\/p>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Store bottles under a roof, keep them dry and clean, free of oil and grease, and keep the space free of flammable materials.<\/p>\n\n\n\n<p>Do not expose to strong heat.<\/p>\n\n\n\n<p>Carried to safety in case of fire.<\/p>\n\n\n\n<p>Precautions should be taken to prevent shocks or falls.<\/p>\n\n\n\n<p>Bottles containing different types of gases must be stored separately.<\/p>\n\n\n\n<p>Keep empty and full bottles separate.<\/p>\n\n\n\n<p>Store and transport standing with the valve closed and the protective plug and cover fitted where such occurs.<\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the bottle.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the package and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is nitrous oxide (nitrous oxide) 100% (Chemical name N&nbsp;<sub>2<\/sub>&nbsp;O)<\/li><li>Niontix contains no other ingredients<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and contents of the pack<\/h2>\n\n\n\n<p>The shoulder of the gas bottle is marked in blue (nitrous oxide).\u00a0The body of the gas bottle is white (medical gas).<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td>Pack sizes in liters<\/td><td>2.5<\/td><td>4<\/td><td>5<\/td><td>10<\/td><td>20<\/td><td>40<\/td><td>50<\/td><td>12&#215;27<\/td><td>9&#215;50<\/td><td>12&#215;40<\/td><td>12&#215;50<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorisation Holder:<\/h2>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td>AGA Gas ABRotev\u00e4gen 2SE-192 78 Sollentuna<\/td><td>Linde Gas ehfBrei\u00f0h\u00f6f\u00f0i 11IS-110 Reykjav\u00edk<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p><strong>Information is provided by<\/strong><\/p>\n\n\n\n<p>Linde Healthcare (a division within Linde Sverige AB)<\/p>\n\n\n\n<p>Tel: 08-731 1000<\/p>\n\n\n\n<p><strong>This medicinal product is authorized under the European Economic Area under the names:<\/strong><\/p>\n\n\n\n<p>Denmark: NIONTIX, 100%, medical gas, liquid<\/p>\n\n\n\n<p>Estonia: NIONTIX, 100%, meditsiiniline veeldatud<\/p>\n\n\n\n<p>Finland: NIONTIX, 100%, l\u00e4\u00e4kkeellinen kaasu, nesteytetty<\/p>\n\n\n\n<p>Iceland: NIONTIX, 100%, liquefied petroleum gas, liquid<\/p>\n\n\n\n<p>Latvia: NIONTIX, 100%, medical medicine, medicine&nbsp;<\/p>\n\n\n\n<p>Lithuania: NIONTIX, 100% medicine, medicine, medicine<\/p>\n\n\n\n<p>Norway: NIONTIX, 100%, medical gas, liquid<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Niontix is \u200b\u200ba gas (nitrous oxide, nitrous oxide) used by inhalation. It has a faintly sweet taste and smell and is colorless. It is provided in a gas bottle that has a valve to control the outflow of gas. The gas bottle contains pure Niontix under such a high pressure that the gas is liquid.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,15581],"tags":[18992,16250,18993,18988,18991,16246,16249,18989,16247,18990,16248],"class_list":["post-19041","post","type-post","status-publish","format-standard","hentry","category-medicines","category-n","tag-benefits-of-niontix","tag-benefits-of-nitric-oxide","tag-medical-nitrous-oxide","tag-niontix","tag-niontix-side-effects","tag-nitric-oxide","tag-nitric-oxide-side-effects","tag-what-is-niontix","tag-what-is-nitric-oxide","tag-what-niontix-is-used-for","tag-what-nitric-oxide-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/19041","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=19041"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/19041\/revisions"}],"predecessor-version":[{"id":19094,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/19041\/revisions\/19094"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=19041"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=19041"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=19041"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}