{"id":18997,"date":"2022-02-26T16:13:26","date_gmt":"2022-02-26T16:13:26","guid":{"rendered":"https:\/\/zeepedia.com\/?p=18997"},"modified":"2022-03-01T10:27:35","modified_gmt":"2022-03-01T10:27:35","slug":"nimotop","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/nimotop\/","title":{"rendered":"Nimotop &#8211; Nimodipine uses, dose and side effects"},"content":{"rendered":"\n<p>30 mg film-coated tablets<br>nimodipine<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Nimotop is and what it is used for<\/h2>\n\n\n\n<p>The active substance in Nimotop tablets is a nimodipine.\u00a0Nimodipine is a calcium antagonist, ie an agent that reduces the influx of calcium ions into certain cells.\u00a0By reducing the influx of calcium ions, contractions of blood vessels and thus lack of oxygen are prevented.<\/p>\n\n\n\n<p>Nimotop tablets are used to prevent or treat symptoms of hypoxia due to vasoconstriction (vasospasm) that occurs after a so-called subarachnoid hemorrhage (bleeding in the fluid-filled cavity surrounding the brain) caused by varicose veins.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before taking Nimotop<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not take Nimotop<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to nimodipine or any of the other ingredients of this medicine (listed in section 6).<\/li><li>concomitantly with rifampicin (for&nbsp;tuberculosis&nbsp;).<\/li><li>concomitantly with phenobarbital, phenytoin, carbamazepine (for&nbsp;epilepsy&nbsp;) or&nbsp;St. John&#8217;s wort&nbsp;.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.<\/p>\n\n\n\n<p>Some medicines can affect or be affected by treatment with Nimotop if taken at the same time.&nbsp;Examples are drugs that contain:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>rifampicin (for&nbsp;tuberculosis&nbsp;)<\/li><li>cimetidine (against acid stomach)<\/li><li>phenobarbital,&nbsp;phenytoin&nbsp;, carbamazepine and&nbsp;valproic acid&nbsp;(for&nbsp;epilepsy&nbsp;)<\/li><li>fluoxetine&nbsp;, nefazodone, nortriptyline (for depression)<\/li><li>St. John&#8217;s wort&nbsp;(herbal remedy for depression)<\/li><li>quinopristine, dalfopristine (for&nbsp;infection&nbsp;)<\/li><li>erythromycin and macrolide class&nbsp;antibiotics&nbsp;(for&nbsp;infection&nbsp;)<\/li><li>telithromycin, clarithromycin (against bacterial infection)<\/li><li>ketoconazole&nbsp;, intraconazole,&nbsp;fluconazole&nbsp;, posaconazole, voriconazole (for fungal infection)<\/li><li>ritonavir and nelfinavir, zidovudine (for&nbsp;HIV&nbsp;)<\/li><li>verapramil,&nbsp;diltiazem&nbsp;(for heart disease)<\/li><li>aprepitant (for nausea in cancer treatment).<\/li><\/ul>\n\n\n\n<p>Nimotop tablets may potentiate the effect of other blood pressure medications used at the same time and your&nbsp;blood pressure&nbsp;may therefore need to be monitored.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Nimotop<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Nimotop with food and drink<\/h2>\n\n\n\n<p>Concomitant intake of grapefruit juice and Nimotop tablets may lead to elevated levels of the drug in the blood.&nbsp;You should therefore avoid taking Nimotop tablets and grapefruit or grapefruit juice at the same time.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, breastfeeding and fertility<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<\/p>\n\n\n\n<p><em>Pregnancy<\/em><\/p>\n\n\n\n<p>There is a risk that the fetus will be affected.&nbsp;Therefore, always consult a doctor before using Nimotop tablets during pregnancy.<\/p>\n\n\n\n<p><em>Breast-feeding<\/em><\/p>\n\n\n\n<p>Nimodipine passes into breast milk and breastfed babies may be affected.\u00a0Therefore, do not use Nimotop tablets while breastfeeding other than on a\u00a0doctor&#8217;s\u00a0prescription.<\/p>\n\n\n\n<p><em>Fertility<\/em><\/p>\n\n\n\n<p>Nimotop may affect men&#8217;s ability to have children.&nbsp;Nimotop is a calcium antagonist, in in vitro fertilization (IVF) there have in some cases been signs that the use of calcium antagonists can lead to impaired sperm function.&nbsp;It is unknown if this has any significance for short-term use.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Due to the risk of dizziness, the ability to react may be reduced when taking Nimotop tablets.&nbsp;This should be taken into account when sharper attention is required e.g.&nbsp;while driving.<\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened vigilance.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects.\u00a0Descriptions of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to take Nimotop<\/h2>\n\n\n\n<p>Always take Nimotop tablets exactly as your doctor has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p>The usual&nbsp;dose&nbsp;is 2 tablets 6 times daily.&nbsp;The tablets should be swallowed whole with liquid and can be taken independently of meals.&nbsp;The time between&nbsp;doses&nbsp;should be at least 4 hours.<\/p>\n\n\n\n<p>Treatment with Nimotop is often started in the hospital as\u00a0an infusion\u00a0for up to 14 days.\u00a0Thereafter, tablets are given for about 7 days as prescribed by a doctor.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Use for children and adolescents<\/h2>\n\n\n\n<p>The safety and efficacy of Nimotop in children and adolescents below 18 years have not been established.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you take more Nimotop than you should<\/h2>\n\n\n\n<p>If you have ingested too much medicine, or if e.g.\u00a0a child ingested the medicine by mistake, contact a doctor or hospital for risk assessment and advice.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, Nimotop tablets can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p>If you get\u00a0any side effects, talk to your doctor or pharmacist.\u00a0This also applies to any\u00a0side effects\u00a0not mentioned in this information.<\/p>\n\n\n\n<p><em>Uncommon (affects less than 1 user in 100)<\/em>: Decreased\u00a0platelets, allergic reactions, rash, headache, fast\u00a0pulse, low\u00a0blood pressure, vasodilation, nausea.<\/p>\n\n\n\n<p><em>Rare (affects less than 1 user in 1,000)<\/em>: Slow\u00a0pulse, bowel movements, altered liver values.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Nimotop<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the carton.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the pack and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is nimodipine 30 mg per tablet.<\/li><li>The other ingredients are povidone, microcrystalline cellulose, maize starch, crospovidone, magnesium stearate, hypromellose, macrogol 4000, titanium dioxide (dye E 171), yellow iron oxide (dye E 172).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and contents of the pack<\/h2>\n\n\n\n<p>The tablets are yellow, round (10 mm in diameter), and marked with SK and Bayer crosses.<\/p>\n\n\n\n<p>Pressure pack with 100 tablets.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p><strong>Marketing Authorisation Holder<\/strong><\/p>\n\n\n\n<p>Bayer AB, Box 606, SE-169 26 Solna<\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>Bayer AG, 51368 Leverkusen, Germany<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The active substance in Nimotop tablets is nimodipine. Nimodipine is a calcium antagonist, ie an agent that reduces the influx of calcium ions into certain cells. By reducing the influx of calcium ions, contractions of blood vessels and thus lack of oxygen are prevented.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,15581],"tags":[18861,18867,18856,18860,18859,18862,18866,18865,18857,18863,18858,18864],"class_list":["post-18997","post","type-post","status-publish","format-standard","hentry","category-medicines","category-n","tag-benefits-of-nimodipine","tag-benefits-of-nimotop","tag-nimodipine","tag-nimodipine-side-effects","tag-nimodipine-tablet","tag-nimotop","tag-nimotop-side-effects","tag-nimotop-tablet","tag-what-is-nimodipine","tag-what-is-nimotop","tag-what-nimodipine-is-used-for","tag-what-nimotop-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/18997","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=18997"}],"version-history":[{"count":5,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/18997\/revisions"}],"predecessor-version":[{"id":19024,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/18997\/revisions\/19024"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=18997"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=18997"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=18997"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}