68 mg implants for subdermal use
etonogestrel<\/p>\n\n\n\n
Nexplanon is a contraceptive implant pre-loaded in a disposable applicator.\u00a0Safety and efficacy have been established in women between 18 and 40 years of age.\u00a0The implant\u00a0is a small, soft, flexible plastic rod 4 cm long and 2 mm in diameter, which contains 68 milligrams of the active substance etonogestrel.\u00a0The applicator allows healthcare professionals to insert\u00a0implants\u00a0just under the skin of your upper arm.\u00a0Etonogestrel is a synthetic female\u00a0hormone\u00a0similar to\u00a0progesterone.\u00a0A small amount of etonogestrel is continuously released into the bloodstream.\u00a0The\u00a0implants\u00a0themselves are made of ethylene-vinyl acetate\u00a0copolymer, a plastic that can not be dissolved in the body.\u00a0It also contains a small amount of barium sulfate which makes it visible on X-rays.<\/p>\n\n\n\n
Nexplanon is used to prevent pregnancy.<\/strong><\/p>\n\n\n\n How Nexplanon works.<\/strong><\/p>\n\n\n\n The implant is inserted directly under the skin. The active substance, etonogestrel, works in two different ways:<\/p>\n\n\n\n As a result, Nexplanon protects against pregnancy for three years, but if you are overweight, your doctor\/midwife may advise you to replace the\u00a0implant\u00a0earlier.\u00a0Nexplanon is one of many ways to prevent pregnancy.\u00a0Another common method is combined\u00a0birth control pills.\u00a0Women who cannot or do not want to use\u00a0estrogen\u00a0can use Nexplanon as opposed to combined\u00a0oral contraceptives.\u00a0When using Nexplanon, you do not need to remember to take one tablet every day.\u00a0This is one of the reasons why Nexplanon is very reliable (over 99% efficiency). In rare cases, the implant has not been inserted correctly or is not inserted at all, the pregnancy protection may not be available.\u00a0When you use Nexplanon, your period may change and not occur, becoming irregular, sparse, denser, longer, and sometimes heavier.\u00a0The bleeding pattern you get in the first three months is usually predictable for the future bleeding pattern.\u00a0Painful menstruation can get better.<\/p>\n\n\n\n You can stop using Nexplanon at any time (see also “When you want to stop using Nexplanon”).<\/p>\n\n\n\n You should not use Nexplanon if you have any of the conditions listed below.\u00a0If any of these apply to you, tell your doctor\/midwife before using Nexplanon.\u00a0Your doctor\/midwife may advise you to use a contraceptive that does not contain\u00a0hormones.<\/p>\n\n\n\n If any of these conditions occur for the first time when you use Nexplanon, contact your doctor\/midwife immediately.<\/strong><\/p>\n\n\n\n Talk to your doctor\/midwife, pharmacist, or nurse before using Nexplanon.<\/p>\n\n\n\n If you are using Nexplanon for any of the conditions listed below, you may need additional controls.\u00a0Your doctor\/midwife can explain what to do.\u00a0If any of these apply to you, tell your doctor\/midwife before using Nexplanon.\u00a0Should any of these occur for the first time or worsen when you use Nexplanon, you must tell your doctor\/midwife.<\/p>\n\n\n\n Conditions that can be serious<\/strong><\/p>\n\n\n\n Cancer<\/strong><\/em><\/p>\n\n\n\n This information has been obtained from studies with women who have taken combined birth\u00a0control pills\u00a0containing two different\u00a0hormones\u00a0(“birth control pills”) every day.\u00a0It is not known whether these observations also apply to women who use another form of hormonal contraceptives, such as\u00a0implants\u00a0that only contain\u00a0progestogens.<\/p>\n\n\n\n Breast cancer is detected slightly more often in women who use combined\u00a0contraceptive pills, but it is not known if it is caused by the treatment.\u00a0For example,\u00a0tumors\u00a0can be found more often in women who use combined\u00a0contraceptive pills\u00a0because they are examined more often by a doctor.\u00a0The increased incidence of breast cancer gradually decreases after stopping the\u00a0pill.\u00a0It is important that you regularly check your breasts and that you contact your doctor if you feel any lump in any of the breasts.\u00a0<\/strong>You should also contact a doctor if a close relative has or has had breast cancer.<\/p>\n\n\n\n In rare cases, benign, and in even more rare cases, malignant, liver tumors have been seen in women using\u00a0birth control pills.\u00a0If you experience severe abdominal pain, contact your doctor immediately.<\/strong><\/p>\n\n\n\n Thrombosis<\/strong><\/em><\/p>\n\n\n\n A blood clot in a vein (called a “deep vein thrombosis”) can block a vein.\u00a0It can occur in the veins of the legs, lungs (\u00a0pulmonary embolism\u00a0), or in other organs.\u00a0A blood clot in an\u00a0artery\u00a0(so-called “arterial thrombosis”) can block an\u00a0artery.\u00a0For example, a blood clot in an\u00a0artery\u00a0can cause a heart attack or a\u00a0stroke\u00a0in the brain.<\/p>\n\n\n\n Using a combined hormonal contraceptive method increases the risk for the woman to get this type of blood clot compared to women who do not use contraceptives with\u00a0hormones.\u00a0The risk is not as great as the risk of getting a blood clot during pregnancy.\u00a0If you use a method that only contains\u00a0progestogens, such as Nexplanon, the risk is considered lower than if you use\u00a0birth control pills\u00a0that also contain\u00a0estrogen.\u00a0There have been reports of blood clots such as\u00a0pulmonary embolism, deep\u00a0vein thrombosis, myocardial infarction, and\u00a0stroke\u00a0in women using etonogestrel implants.\u00a0However, available data do not indicate an increased risk of these events in women who use implants\u00a0et.<\/p>\n\n\n\n If you notice any signs of\u00a0thrombosis, contact your doctor immediately.\u00a0<\/strong>(see also\u00a0“When to contact your doctor”<\/em>\u00a0).<\/p>\n\n\n\n Other conditions<\/strong><\/p>\n\n\n\n Changes in the menstrual bleeding pattern<\/strong><\/em><\/p>\n\n\n\n As with all progestogen-only contraceptive methods, the menstrual bleeding pattern may change when using Nexplanon.\u00a0You may experience a change in frequency (no, fewer, more frequent, or continuous bleeding), amount (decreased or increased), or duration.\u00a0The fact that bleeding completely disappears has been reported in approximately 1 in 5 women, while another 1 in 5 women reported more frequent or prolonged bleeding.\u00a0Occasionally there have been heavy bleeding.\u00a0In\u00a0clinical trials altered bleeding was the most common reason for stopping (approximately 11%).\u00a0The bleeding pattern you get in the first three months is usually predictable for the future bleeding pattern.\u00a0The fact that the bleeding changes does not mean that Nexplanon does not suit you or does not give you sufficient protection.\u00a0In general, you do not need to do anything.\u00a0You should contact your doctor\/midwife if your menstrual bleeding becomes heavy or prolonged.<\/p>\n\n\n\n Events that have to do with deposits and withdrawals<\/strong><\/em><\/p>\n\n\n\n The implant\u00a0can move from the original insertion point in the arm, if it has not been inserted correctly, or if it has been exposed to external influences (eg if you have tampered with the\u00a0implant\u00a0or at contact ports).\u00a0In rare cases,\u00a0implants\u00a0have been located in the blood vessel of the armor in the pulmonary artery (a blood vessel in the lung).\u00a0In cases where the\u00a0implant\u00a0has moved from the original insertion site, it may be more difficult to locate and remove the\u00a0implant\u00a0and it may be necessary to make a larger incision or surgical removal in the hospital.\u00a0If the\u00a0implant\u00a0cannot be located in the arm, the doctor\/midwife can use X-rays or other methods on the chest.\u00a0If implants\u00a0are found in the chest,\u00a0surgery\u00a0may be necessary.\u00a0If you cannot find the\u00a0implant, and there is no indication that it has been rejected, the protection against pregnancy and the risk of progestogenic\u00a0side effects\u00a0may persist for longer than you wish.<\/p>\n\n\n\n If it is not possible to feel the\u00a0implant\u00a0at any time,\u00a0contact your doctor\/midwife immediately.<\/strong><\/p>\n\n\n\n Mental disorders<\/em><\/strong><\/p>\n\n\n\n Some women who use hormonal contraceptives, including Nexplanon, have reported depression or depression. Depression can be severe and can sometimes lead to suicidal thoughts. If you experience mood swings and symptoms of depression, you should contact a doctor as soon as possible for advice.<\/p>\n\n\n\n Ovarian cysts<\/strong><\/em><\/p>\n\n\n\n When using low-dose hormonal contraceptives, you can get small fluid-filled blisters on the ovaries. They are called ovarian cysts. They usually disappear on their own. Sometimes they can cause mild abdominal pain. Only in exceptional cases can they lead to more serious problems.<\/p>\n\n\n\n Broken or bent implants<\/em><\/strong><\/p>\n\n\n\n If the\u00a0implant\u00a0breaks or bends in the arm, it should not affect how the\u00a0implant\u00a0works.\u00a0The implant\u00a0can break or bend if exposed to external forces.\u00a0The broken\u00a0implant\u00a0can move from the insertion site.\u00a0If you have any questions, contact your doctor\/midwife.<\/p>\n\n\n\nWhat you need to know before you use Nexplanon<\/h2>\n\n\n\n
Hormonal contraceptives, including Nexplanon, do not protect against HIV infection (AIDS) or other sexually transmitted diseases.<\/h2>\n\n\n\n
Do not use Nexplanon<\/h2>\n\n\n\n
Warnings and cautions<\/h2>\n\n\n\n
Other medicines and Nexplanon<\/h2>\n\n\n\n