5 mg, 10 mg, 15 mg, 20 mg film-coated tablets
memantine hydrochloride<\/p>\n\n\n\n
How Nemdatine works<\/strong><\/p>\n\n\n\n Nemdatine belongs to a group of medicines known as anti-dementia medicines. Memory loss in Alzheimer’s disease is due to a disturbance of message signals in the brain. The brain contains so-called NMDA receptors (N-methyl-D-aspartate) which have to do with the transmission of nerve signals that are important for learning and memory. Nemdatine belongs to a group of medicines called NMDA receptor antagonists. Nemdatine acts on these NMDA receptors by improving the transmission of nerve signals and memory.<\/p>\n\n\n\n What Nemdatine is used for<\/strong><\/p>\n\n\n\n Nemdatine is used to treat patients with moderate to severe\u00a0Alzheimer’s disease.<\/p>\n\n\n\n Do not use Nemdatine<\/strong><\/p>\n\n\n\n Talk to your doctor or pharmacist before using Nemdatine.<\/p>\n\n\n\n In these situations, treatment should be closely monitored and the clinical benefit of Nemdatine should be regularly assessed by your doctor.<\/p>\n\n\n\n If you suffer from impaired kidney function (kidney problems), your doctor should closely monitor your kidney function and, if necessary, adjust the memantine doses accordingly.<\/p>\n\n\n\n Concomitant use of drugs containing amantadine (for the treatment of\u00a0Parkinson’s disease\u00a0), ketamine (a substance commonly used as an anesthetic), dextromethorphan (generally used to treat cough), and other NMDA\u00a0antagonists\u00a0should be avoided.<\/p>\n\n\n\n Nemdatine is not recommended for children and adolescents under 18 years of age.<\/p>\n\n\n\n Tell your doctor or pharmacist if you are taking or have recently taken or might take any other medicines, including medicines obtained without a prescription.<\/p>\n\n\n\n Nemdatine may particularly affect the effects of the following medicines and these doses may need to be changed by your doctor:<\/p>\n\n\n\n If you are hospitalized, tell your doctor that you are taking Nemdatine.<\/p>\n\n\n\n You should tell your doctor if you have recently changed or plan to change your diet decisively (eg from a regular diet to a vegetarian diet only) or if you have\u00a0renal\u00a0tubular\u00a0acidosis\u00a0(RTA, an excess of acid-forming substances). in the blood as a result of renal dysfunction (poor kidney function)) or severe urinary tract infections, as your doctor may need to adjust the\u00a0dose\u00a0of your medicine.<\/p>\n\n\n\n If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<\/p>\n\n\n\n The use of memantine in pregnant women is not recommended.<\/p>\n\n\n\n Women taking Nemdatine should not breastfeed.<\/p>\n\n\n\n Your doctor will tell you if your illness allows you to drive and use machines safely. Nemdatine may also alter your reactivity, making it unsuitable to drive or use machines. Nemdatine contains lactose monohydrate<\/strong><\/p>\n\n\n\n If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking Nemdatine. <\/p>\n\n\n\n Always use Nemdatine exactly as your doctor or pharmacist has told you. Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n Nemdatine starter pack should only be used at the beginning of treatment with Nemdatine.<\/p>\n\n\n\n Dosage<\/strong><\/p>\n\n\n\n The recommended treatment dose of 20 mg per day is achieved by gradually increasing the Nemdatine dose one during the first 3 weeks of treatment. The treatment schedule is also stated on starter pack one. Take one tablet once a day.<\/p>\n\n\n\n Week 1 (day 1-7): Week 2 (days 8-14): Week 3 (day 15-21): Week 4 (day 22-28): Maintenance dose<\/strong><\/p>\n\n\n\n The recommended daily dose is 20 mg once daily.<\/p>\n\n\n\n To continue treatment, consult your doctor.<\/p>\n\n\n\n Dosage in patients with renal impairment<\/strong><\/p>\n\n\n\n If you have impaired kidney function, your doctor will prescribe a dose that suits your condition. Your doctor should examine your kidney function at certain intervals.<\/p>\n\n\n\n Administration<\/strong><\/p>\n\n\n\n Nemdatine should be taken orally once a day.\u00a0For you to benefit from your medicine, you must take it regularly every day at the same time of day.\u00a0The tablets should be swallowed with a little water.\u00a0The tablets can be taken with or without food.<\/p>\n\n\n\n Treatment time<\/strong><\/p>\n\n\n\n Keep taking Nemdatine for as long as you can. Your doctor should regularly evaluate your treatment.<\/p>\n\n\n\n If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them. In general, the side effects observed are mild to moderate.<\/p>\n\n\n\n Common (affects 1 to 10 users in 100):<\/em><\/p>\n\n\n\n Uncommon (affects 1 to 10 users in 1,000):<\/em><\/p>\n\n\n\n Very rare (affects less than 1 user in 10,000):<\/em><\/p>\n\n\n\n No known frequency (can not be calculated from the available data):<\/em><\/p>\n\n\n\n Alzheimer’s disease\u00a0has been associated with depression, suicidal ideation, and self-loathing.\u00a0These events have been reported in patients treated with Nemdatine.<\/p>\n\n\n\n Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n Do not use this medicine after the expiry date which is stated on the carton and blister after EXP. The expiration date is the last day of the specified month. Do not store above 25 \u00b0 C. Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.<\/p>\n\n\n\n Nemdatine 5 mg film-coated tablets (tablets) are white, oval, biconvex, 8 mm x 4.5 mm in size, marked \u201cM5\u201d on one side. A\u00a0starter\u00a0pack contains 28 tablets in 4 blisters in a wallet pack or multiple packs of 4 blisters in 4 separate inner packs and an outer pack of 7 tablets Nemdatine 5 mg, 7 tablets Nemdatine 10 mg, 7 tablets Nemdatine 15 mg, and 7 tablets Nemdatine 20 mg.<\/p>\n\n\n\n Marketing Authorization Holder<\/em> Manufacturer<\/em> Actavis Group PTC EHF.<\/p>\n\n\n\n Reykjavikurvegur 76-78<\/p>\n\n\n\n 220 Hafnarfjordur<\/p>\n\n\n\n Iceland<\/p>\n\n\n\n Actavis Ltd. Manufacturing Packaging Farmacia (MPF) BV<\/p>\n\n\n\n Neptune 12,<\/p>\n\n\n\n Heerenveen 8448CN<\/p>\n\n\n\n Netherlands<\/p>\n\n\n\n Manufacturing Packaging Farmacia (MPF) BV<\/p>\n\n\n\n Appelhof 13,<\/p>\n\n\n\n Oudehask, 8465RX<\/p>\n\n\n\n Netherlands<\/p>\n","protected":false},"excerpt":{"rendered":" Nemdatine belongs to a group of medicines known as anti-dementia medicines. Memory loss in Alzheimer’s disease is due to a disturbance of message signals in the brain. The brain contains so-called NMDA receptors (N-methyl-D-aspartate) which have to do with the transmission of nerve signals that are important for learning and memory. Nemdatine belongs to a group of medicines called NMDA receptor antagonists. Nemdatine acts on these NMDA receptors by improving the transmission of nerve signals and memory.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,15581],"tags":[16805,18589,4842,4844,18584,18587,18588,4843,18585,16804,18586],"class_list":["post-18805","post","type-post","status-publish","format-standard","hentry","category-medicines","category-n","tag-benefits-of-memantine-hydrochloride","tag-benefits-of-nemdatine","tag-memantine-hydrochloride","tag-memantine-hydrochloride-side-effects","tag-nemdatine","tag-nemdatine-side-effects","tag-nemdatine-tablet","tag-what-is-memantine-hydrochloride","tag-what-is-nemdatine","tag-what-memantine-hydrochloride-is-used-for","tag-what-nemdatine-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/18805","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=18805"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/18805\/revisions"}],"predecessor-version":[{"id":18835,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/18805\/revisions\/18835"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=18805"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=18805"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=18805"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}What you need to know before using Nemdatine<\/h2>\n\n\n\n
Do not use Nemdatine<\/h2>\n\n\n\n
<\/li><\/ul>\n\n\n\nWarnings and cautions<\/h2>\n\n\n\n
Children and young people<\/h2>\n\n\n\n
Other medicines and Nemdatine<\/h2>\n\n\n\n
Nemdatine with food and drink<\/h2>\n\n\n\n
Pregnancy, breastfeeding and fertility<\/h2>\n\n\n\n
Driving and using machines<\/h2>\n\n\n\n
<\/p>\n\n\n\nHow to use Nemdatine<\/h2>\n\n\n\n
Take one 5 mg tablet once a day (white, oval) for 7 days.<\/p>\n\n\n\n
Take one 10 mg tablet once a day (white, capsule-shaped) for 7 days.<\/p>\n\n\n\n
Take a 15 mg tablet once daily (orange, oval) for 7 days.<\/p>\n\n\n\n
Take one 20 mg tablet per day (dark pink, oval) for 7 days.<\/p>\n\n\n\nWeek 1<\/td> 5 mg tablet<\/td><\/tr> Week 2<\/td> 10 mg tablet<\/td><\/tr> Week 3<\/td> 15 mg tablet<\/td><\/tr> Week 4 and beyond<\/td> 20 mg tablet once daily<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n If you use more Nemdatine than you should <\/h2>\n\n\n\n
If you forget to use Nemdatine<\/h2>\n\n\n\n
Possible side effects<\/h2>\n\n\n\n
<\/p>\n\n\n\n
<\/li><\/ul>\n\n\n\nHow to store Nemdatine<\/h2>\n\n\n\n
<\/p>\n\n\n\n
<\/p>\n\n\n\nContents of the pack and other information<\/h2>\n\n\n\n
Content declaration<\/h2>\n\n\n\n
Tablet coating:<\/em> Hypromellose 6cP, titanium dioxide (E 171), lactose monohydrate , macrogol 3350 and triacetin. Nemdatine 15 mg also contains yellow, red and black iron oxide (E172). Nemdatine 20 mg film-coated tablets also contain red and yellow iron oxide (E 172).<\/li><\/ul>\n\n\n\nWhat the medicine looks like and contents of the pack<\/h2>\n\n\n\n
Nemdatine 10 mg film-coated tablets (tablets) are white, capsule-shaped, oval, biconvex, 9.8 mm x 4.9 mm in size, with a scoreline, marked \u201cM 10\u201d on the page with a scoreline.
Nemdatine 15 mg film-coated tablets (tablets) are orange, oval, biconvex, 11.4 mm x 6.4 mm in size marked \u201cM15\u201d on one side.
Nemdatine 20 mg film-coated tablets (tablets) are dark pink, oval, biconvex, 12.6 mm x 7 mm in size, marked \u201cM20\u201d on one side.<\/p>\n\n\n\nMarketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n
Actavis Group PTC EHF.
Reykjav\u00edkurvegur 76\u201178
220 Hafnarfj\u00f6r\u00f0ur
Iceland<\/p>\n\n\n\n
Actavis hf.
Reykjav\u00edkurvegur 78
220 Hafnarfj\u00f6r\u00f0ur
Iceland<\/p>\n\n\n\n
BLB 016 Bulebel Industrial Estate
Zejtun ZTN 3000
Malta<\/p>\n\n\n\n