0.4 mg \/ ml solution for injection \/ infusion
naloxone hydrochloride<\/p>\n\n\n\n
Naloxone Hameln 0.4 mg\/ml is a medicine that counteracts the effects of opioid overdose, e.g.\u00a0overdose with morphine.<\/p>\n\n\n\n
Naloxone Hameln 0.4 mg\/ml is used to eliminate the unwanted effects of\u00a0opioids\u00a0to counteract life-threatening paralysis of the\u00a0central nervous system\u00a0and respiration (difficulty breathing).
Naloxone Hameln 0.4 mg\/ml is also used to diagnose\u00a0acute\u00a0opioid overdose or poisoning.<\/p>\n\n\n\n
If a woman has been given painkillers during childbirth, the newborn baby can be treated with Naloxone Hameln 0.4 mg\/ml to eliminate the unwanted effects of\u00a0opioids, e.g.\u00a0if he\/she suffers from breathing difficulties or depression of the\u00a0central nervous system.<\/p>\n\n\n\n
Naloxone hydrochloride contained in Naloxone Hameln 0.4 mg\/ml may also be approved for the treatment of other conditions not mentioned in this product information.\u00a0Ask your doctor, pharmacist, or healthcare professional if you have any further questions, and always follow their instructions.<\/p>\n\n\n\n
Talk to your doctor or pharmacist before using Naloxone Hameln 0.4 mg\/ml.<\/p>\n\n\n\n
Take special care with Naloxone Hameln 0.4 mg\/ml and tell your doctor<\/strong><\/p>\n\n\n\n Tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.<\/p>\n\n\n\n Tell your doctor if you have been drinking alcohol.\u00a0In patients with mixed poisoning (\u00a0opioid\u00a0poisoning and sedatives or alcohol), the effect of Naloxone Hameln 0.4 mg\/ml may be slower.<\/p>\n\n\n\n There are insufficient data available on the use of Naloxone Hameln 0.4 mg\/ml in pregnant women.\u00a0During pregnancy, your doctor will consider the benefits of Naloxone Hameln 0.4 mg\/ml against the potential risks to the fetus. If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<\/p>\n\n\n\n After receiving Naloxone Hameln 0.4 mg\/ml to counteract the effects of\u00a0opioids, do not drive, use machines or perform other physically or mentally demanding activities for at least 24 hours, as the effects of opioids may recur.<\/p>\n\n\n\n You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened vigilance.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects.\u00a0Descriptions of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n This medicine contains 3.54 mg\u00a0sodium\u00a0(the main ingredient in table salt\/table salt) per ml.\u00a0This corresponds to 0.2% of the maximum recommended daily intake of\u00a0sodium\u00a0for adults.<\/p>\n\n\n\n The usual doses given to you are<\/strong><\/p>\n\n\n\n Elimination of the undesirable effects of opioids:<\/em> Diagnosis of opioid overdose or poisoning:<\/em> Elimination of the undesirable effects of opioids in newborns whose mothers received opioids is<\/em> To eliminate the undesirable effects of\u00a0opioids\u00a0(in adults, children, and even newborns), patients are monitored to ensure that the desired effect of Naloxone Hamelin 0.4 mg\/ml is achieved. Naloxone Hameln 0.4 mg\/ml should be used with caution\u00a0in elderly patients with cardiac or circulatory problems or patients who have used agents that may cause cardiovascular disorders (eg cocaine, methamphetamine, tricyclic antidepressants,\u00a0calcium channel\u00a0blockers,\u00a0beta-blockers,\u00a0digoxin\u00a0), as serious\u00a0side effects, such as rapid heartbeat (\u00a0ventricular tachycardia\u00a0) and fibrillation have occurred.<\/p>\n\n\n\n If you have the impression that the effect of Naloxone Hameln 0.4 mg\/ml is too strong or too weak, talk to your doctor.<\/p>\n\n\n\n Method of administration<\/strong><\/p>\n\n\n\n Naloxone Hameln 0.4 mg\/ml is always given as an\u00a0intravenous\u00a0or\u00a0intramuscular\u00a0injection\u00a0(into a vein or a muscle) or, after dilution, as an\u00a0intravenous\u00a0infusion\u00a0(over a long period).\u00a0Naloxone Hameln 0.4 mg\/ml will be given to you by your anesthetist or another experienced physician.<\/p>\n\n\n\n If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n It can be difficult to know what\u00a0side effects\u00a0Naloxone Hameln 0.4 mg\/ml has because it is always given after other substances have also been used.<\/p>\n\n\n\n Very common (may affect more than 1 user in 10):<\/em><\/p>\n\n\n\n – Nausea<\/p>\n\n\n\n Common (may affect up to 1 in 10 people):<\/em><\/p>\n\n\n\n – Dizziness<\/p>\n\n\n\n – Headache<\/p>\n\n\n\n – Fast heart rate<\/p>\n\n\n\n Elevated or decreased blood pressure (you may have a headache or feel dizzy)<\/p>\n\n\n\n Vomiting<\/p>\n\n\n\n – If an overdose is given after an operation, you may experience a hypersensitive condition and feel pain (because the pain-relieving effects of the medicines you have been given have also been counteracted as well as the effects on your breathing).<\/p>\n\n\n\n Uncommon (may affect up to 1 in 100 people):<\/em><\/p>\n\n\n\n – Involuntary trembling or shaking<\/p>\n\n\n\n – Sweating<\/p>\n\n\n\n – Changes in heart rhythm<\/p>\n\n\n\n – Slow heart rate<\/p>\n\n\n\n – Diarrhea<\/p>\n\n\n\n – Dry mouth<\/p>\n\n\n\n – Hyperventilation<\/p>\n\n\n\n Irritation of the blood vessel wall has been reported after intravenous administration<\/p>\n\n\n\n – Local irritation and inflammation have been reported after intramuscular administration<\/p>\n\n\n\n Rare (may affect up to 1 in 1,000 people):<\/em><\/p>\n\n\n\n – Seizures<\/p>\n\n\n\n – Nerve tension<\/p>\n\n\n\n Very rare (may affect up to 1 in 10,000 people):<\/em><\/p>\n\n\n\n – Allergic reactions (\u00a0hives, runny nose or cold, difficulty breathing,\u00a0Quincke’s edema\u00a0(severe swelling))<\/p>\n\n\n\n – Allergic shock<\/p>\n\n\n\n – Heart fibrillation<\/p>\n\n\n\n Cardiac arrest<\/p>\n\n\n\n – Accumulation of fluid in the lungs ( pulmonary edema )<\/p>\n\n\n\n – Discoloration and damage to the skin (erythema multiforme)<\/p>\n\n\n\n Keep this medicine out of the sight and reach of children. Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.<\/p>\n\n\n\n Naloxone Hameln 0.4 mg\/ml is a clear and colorless liquid in a colorless\u00a0glass ampoule\u00a0containing 1 ml solution for injection\/infusion.<\/p>\n\n\n\n Pack sizes: 5 and 10\u00a0ampoules.<\/p>\n\n\n\n Not all pack sizes may be marketed.<\/p>\n\n\n\n Marketing Authorisation Holder:<\/strong><\/p>\n\n\n\n Hameln pharma gmbh 31787 Hameln Manufacturer:<\/strong><\/p>\n\n\n\n Siegfried Hameln GmbH This medicinal product is authorized under the European Economic Area under the names:<\/strong><\/p>\n\n\n\n Naloxone Hameln 0.4 mg \/ ml is a medicine that counteracts the effects of opioid overdose, e.g. overdose with morphine.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,15581],"tags":[18373,18368,18369,18372,18364,18367,18370,18365,18371,18366],"class_list":["post-18577","post","type-post","status-publish","format-standard","hentry","category-medicines","category-n","tag-benefits-of-naloxone-hameln","tag-benefits-of-naloxone-hydrochloride","tag-naloxone-hameln","tag-naloxone-hameln-side-effects","tag-naloxone-hydrochloride","tag-naloxone-hydrochloride-side-effects","tag-what-is-naloxone-hameln","tag-what-is-naloxone-hydrochloride","tag-what-naloxone-hameln-is-used-for","tag-what-naloxone-hydrochloride-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/18577","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=18577"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/18577\/revisions"}],"predecessor-version":[{"id":18633,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/18577\/revisions\/18633"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=18577"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=18577"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=18577"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}Other medicines and Naloxone Hameln 0.4 mg \/ ml<\/h2>\n\n\n\n
Naloxone Hameln 0.4 mg \/ ml with food, drink and alcohol<\/h2>\n\n\n\n
Pregnancy and breastfeeding<\/h2>\n\n\n\n
It is not known whether Naloxone Hameln 0.4 mg\/ml passes into breast milk and it has not been established whether breastfed infants can be affected by Naloxone Hameln 0.4 mg\/ml.\u00a0Breast-feeding should therefore be avoided for up to 24 hours after treatment.<\/p>\n\n\n\nDriving and using machines<\/h2>\n\n\n\n
Naloxone Hameln 0.4 mg \/ ml contains sodium<\/h2>\n\n\n\n
How Naloxone Hameln 0.4 mg \/ ml is administered<\/h2>\n\n\n\n
Adults: 0.1 – 0.2 mg, if necessary further injections of 0.1 mg may be given.
Children: 0.01 – 0.02 mg per kg body weight, if necessary additional injections of the same dose can be given.<\/p>\n\n\n\n
Adults: 0.4 – 2 mg, the injections can be repeated if necessary at 2-3 minute intervals. The maximum dose of 10 mg should not be exceeded.
Children: 0.01 mg per kg body weight, if necessary dose one is increased<\/strong> in the next injection to 0.1 mg per kg.<\/p>\n\n\n\n
0.01 mg per kg body weight, if necessary further injection may be given.<\/p>\n\n\n\n
Additional\u00a0dose\u00a0er can be given at 1-2 hour intervals, if necessary.<\/p>\n\n\n\nPossible side effects<\/h2>\n\n\n\n
How to store Naloxone Hameln 0.4 mg \/ ml<\/h2>\n\n\n\n
Do not use this medicine after the expiry date which is stated on the ampoule label and the carton after “EXP” or “EXP”.\u00a0The expiration date is the last day of the specified month.
Store the\u00a0ampoules\u00a0in the outer carton.\u00a0Sensitive to light.
Do not store above 25 \u00b0 C.
Dilute solutions at a maximum of 25 \u00baC.<\/p>\n\n\n\nContents of the pack and other information<\/h2>\n\n\n\n
Content declaration<\/h2>\n\n\n\n
What the medicine looks like and contents of the pack<\/h2>\n\n\n\n
Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n
Inselstra\u00dfe 1<\/p>\n\n\n\n
Germany<\/p>\n\n\n\n
Langes Feld 13
31789 Hameln
Germany<\/p>\n\n\n\nDenmark<\/em><\/td> Naloxone Hameln 0.4 mg \/ ml solution for injection \/ infusion<\/em><\/td><\/tr> Netherlands<\/em><\/td> Naloxone HCl -hameln 0.4 mg \/ ml, solution for injection \/ infusion<\/em><\/td><\/tr> Norway<\/em><\/td> Naloxone Hameln 0.4 mg \/ ml solution for injection \/ infusion<\/em><\/td><\/tr> UK<\/em><\/td> Naloxone 400 micrograms \/ ml solution for injection \/ infusion<\/em><\/td><\/tr> Sweden<\/em><\/td> Naloxone Hameln 0.4 mg \/ ml solution for injection or infusion<\/em><\/td><\/tr> Germany<\/em><\/td> Naloxone hameln 0.4 mg \/ ml solution for injection or infusion<\/em><\/td><\/tr><\/tbody><\/table><\/figure>\n","protected":false},"excerpt":{"rendered":"