{"id":18327,"date":"2022-02-15T15:15:13","date_gmt":"2022-02-15T15:15:13","guid":{"rendered":"https:\/\/zeepedia.com\/?p=18327"},"modified":"2022-02-16T10:19:49","modified_gmt":"2022-02-16T10:19:49","slug":"morphine-calcex","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/morphine-calcex\/","title":{"rendered":"Morphine Calcex &#8211; Morphine hydrochloride uses, dose and side effects"},"content":{"rendered":"\n<p>10 mg \/ ml&nbsp;solution&nbsp;for injection<br>morphine hydrochloride<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Morphine Kalceks is and what it is used for<\/h2>\n\n\n\n<p>Morphine Kalceks contains the active substance morphine and is part of a group of medicines called natural opium alkaloids.\u00a0This medicine is used to relieve severe pain when other painkillers do not have sufficient effect.<\/p>\n\n\n\n<p>Morphine contained in Morphine Kalceks may also be approved for the treatment of other diseases not mentioned in this product information.\u00a0Ask your doctor, pharmacist, or another healthcare professional if you have any further questions, and always follow their instructions.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before you use Morphine Kalceks<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Morphine Kalceks<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to morphine hydrochloride or any of the other ingredients of this medicine.&nbsp;(listed in section 6).<\/li><li>in conditions with a lot of mucus in the airways<\/li><li>in case of impaired respiratory function<\/li><li>in&nbsp;acute&nbsp;liver disease<\/li><li>in case of anxiety in patients who are under the influence of alcohol or sleeping pills<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>There is a risk of habit formation with Morphine Kalceks.<\/p>\n\n\n\n<p>Talk to your doctor, pharmacist, or nurse before using Morphine Kalceks if you:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>is addicted to other painkillers (&nbsp;opioids&nbsp;)<\/li><li>get&nbsp;peritoneal&nbsp;dialysis<\/li><li>have&nbsp;asthma<\/li><li>have cramps in the airways<\/li><li>has head injury<\/li><li>have low&nbsp;blood pressure&nbsp;with decreased blood volume<\/li><li>has impaired thyroid function<\/li><li>have impaired liver or kidney function<\/li><li>have&nbsp;inflammatory&nbsp;bowel disease<\/li><li>have&nbsp;inflammation&nbsp;of the pancreas<\/li><li>have cramps in the bile ducts or ureters<\/li><li>has enlarged&nbsp;prostate<\/li><li>has&nbsp;myasthenia gravis&nbsp;(a disease with muscle weakness)<\/li><li>have concomitant treatment with&nbsp;MAO inhibitors&nbsp;(antidepressants)<\/li><\/ul>\n\n\n\n<p>Talk to your doctor, pharmacist, or nurse if you experience any of the following symptoms while using Morphine Kalceks:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>increased pain sensitivity even though you are taking increasing&nbsp;doses&nbsp;(hyperalgesia).&nbsp;Your doctor will decide if you need to change the&nbsp;dose&nbsp;or switch to another strong&nbsp;analgesic&nbsp;(painkiller), (see section 2)<\/li><li>weakness, fatigue, loss of appetite, nausea, vomiting or low&nbsp;blood pressure&nbsp;.&nbsp;This can be a symptom that the adrenal glands are producing too little of the&nbsp;hormone&nbsp;et&nbsp;cortisol&nbsp;, and you may therefore need to take hormone supplements<\/li><li>loss of&nbsp;libido&nbsp;,&nbsp;impotence&nbsp;, missed periods.&nbsp;This may be due to decreased production of sex hormones<\/li><li>if you have once been addicted to drugs or alcohol.&nbsp;Also tell us if you feel you are becoming addicted to Morphine Kalceks while using it.&nbsp;You may have started thinking a lot about when you can take the next&nbsp;dose&nbsp;, even if you do not need it for the pain<\/li><li>withdrawal symptoms or addiction.&nbsp;The most common withdrawal symptoms are mentioned in section 3. If this happens, your doctor may change the type of medicine or the times between&nbsp;doses&nbsp;.<\/li><\/ul>\n\n\n\n<p>In the treatment of elderly patients, a lower&nbsp;dose of&nbsp;Morphine Kalceks is recommended.<\/p>\n\n\n\n<p>This medicine should not be used to treat the pain of unknown origin or for pain associated with mental illness.<\/p>\n\n\n\n<p>This medicine should not be given alone during gallstone or kidney stone attacks as it may increase seizures.&nbsp;In such cases, Morphine Kalceks should be given in combination with antispasmodics (&nbsp;antispasmodics&nbsp;).<\/p>\n\n\n\n<p>The effect of this drug may be\u00a0exacerbated\u00a0after\u00a0encephalitis.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Morphine Kalceks<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.\u00a0This is especially important if you are taking:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>rifampicin to e.g.&nbsp;treat&nbsp;tuberculosis<\/li><li>Concomitant use of Morphine Kalceks and&nbsp;sedatives&nbsp;such as&nbsp;benzodiazepines&nbsp;or related drugs increases the risk of drowsiness, difficulty breathing (&nbsp;respiratory depression&nbsp;) and&nbsp;coma&nbsp;, and may be life-threatening.&nbsp;Concomitant use should therefore only be considered when other treatment options are lacking.&nbsp;However, if your doctor prescribes Morphine Kalceks together with&nbsp;sedative&nbsp;medicines, your doctor should limit the&nbsp;dose&nbsp;and the duration of concomitant treatment.&nbsp;Tell your doctor about all&nbsp;sedativesmedicines you are taking, and carefully follow your doctor&#8217;s dose recommendation.&nbsp;It may be helpful to ask friends or relatives to be aware of the signs and symptoms mentioned above.&nbsp;Contact a doctor when you experience such symptoms.<\/li><\/ul>\n\n\n\n<p>The effect of the treatment can be affected if Morphine Kalceks is taken at the same time as certain other medicines.<\/p>\n\n\n\n<p><em>Combinations to avoid with Morphine Kalceks:<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>sedatives and sleeping pills containing&nbsp;barbiturates&nbsp;(methohexital, pentotal, phenobarbital)<\/li><li>antidepressants or Parkinson&#8217;s syndrome (MAO inhibitors) (moclobemide,&nbsp;selegiline&nbsp;)<\/li><\/ul>\n\n\n\n<p>These medicines, in combination with Morphine Kalceks, may impair respiratory function.<\/p>\n\n\n\n<p><em>Drugs that may require dose adjustment:<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>antiepileptic drugs (&nbsp;gabapentin&nbsp;)<\/li><li>antidepressants (clomipramine, amitriptyline, nortriptyline)<\/li><li>some other painkillers (buprenorphine, nalbufine, pentazocine)<\/li><\/ul>\n\n\n\n<p><em>Other drugs that can affect or be affected by Morphine Kalceks:<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>anticonvulsant drug (baclofen)<\/li><li>sedatives containing&nbsp;benzodiazepines&nbsp;(nitrazepam,&nbsp;flunitrazepam&nbsp;, triazolam, midazolam)<\/li><li>sedative drugs that reduce&nbsp;itching&nbsp;(&nbsp;hydroxizine&nbsp;)<\/li><li>central stimulant drug (methylphenidate)<\/li><li>medicines for bleeding in the meninges (nimodipine)<\/li><li>anti- HIV&nbsp;drugs&nbsp;(ritonavir)<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Mofin Kalceks with alcohol<\/h2>\n\n\n\n<p>Combination with alcohol should be avoided as respiratory function may be impaired.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, breastfeeding and fertility<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<\/p>\n\n\n\n<p><em>Fertility<\/em><\/p>\n\n\n\n<p>In animal studies, this drug has shown&nbsp;side effects&nbsp;on animal&nbsp;fertility&nbsp;and it can cause harm to the growing fetus.&nbsp;Therefore, fertile women and men should use effective contraception.&nbsp;Discuss this with your doctor.<\/p>\n\n\n\n<p><em>Pregnancy<\/em><\/p>\n\n\n\n<p>With long-term use of Morphine Kalceks during pregnancy, there is a risk that the newborn baby will develop symptoms of drug withdrawal (\u00a0abstinence\u00a0) which must be treated by a doctor.\u00a0The use of morphine during childbirth may cause the newborn to have impaired respiratory function.<\/p>\n\n\n\n<p><em>Breast-feeding<\/em><\/p>\n\n\n\n<p>Morphine passes into breast milk.\u00a0Morphine Kalceks should therefore not be used during breastfeeding.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>You must not drive or use machines when you receive Morphine Kalceks.&nbsp;This medicine may affect your ability to react.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to use Morphine Kalceks<\/h2>\n\n\n\n<p>Always use this medicine exactly as your doctor or pharmacist has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p>Dose\u00a0one is individual and determined by a doctor.\u00a0It depends on your age, weight, the severity of the pain, and previous medication and pain.<\/p>\n\n\n\n<p><em>Older<\/em><\/p>\n\n\n\n<p>You will receive a lower\u00a0dose.<\/p>\n\n\n\n<p><em>Hepatic or renal impairment<\/em><\/p>\n\n\n\n<p>You will receive a lower\u00a0dose.<\/p>\n\n\n\n<p>The dose\u00a0may need to be reduced for patients with\u00a0bronchial asthma,\u00a0upper respiratory tract\u00a0obstruction, head injuries,\u00a0peritoneal dialysis, low\u00a0blood pressure\u00a0with reduced blood volume, decreased thyroid function, inflammatory bowel disease,\u00a0inflammation\u00a0of the pancreas, urinary tract spasms.<\/p>\n\n\n\n<p>It can be given\u00a0intravenously,\u00a0intramuscularly,\u00a0or\u00a0subcutaneously.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you use more Morphine Kalceks than you should &nbsp;<\/h2>\n\n\n\n<p>Symptoms of overdose include pin-sized\u00a0pupils, low\u00a0blood pressure, difficulty breathing leading to unconsciousness or even death.\u00a0People who have taken an overdose can get\u00a0pneumonia\u00a0by pulling down vomit or foreign matter in the lungs, with symptoms such as shortness of breath, cough, and fever.\u00a0Circulatory disorders and\u00a0coma\u00a0can occur in severe cases.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to use Morphine Kalceks<\/h2>\n\n\n\n<p>Do not take a double\u00a0dose\u00a0to make up for a forgotten\u00a0dose.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop using Morphine Kalceks<\/h2>\n\n\n\n<p>Withdrawal symptoms may occur if you suddenly stop taking Morphine Kalceks or if you use certain other strong painkillers.<\/p>\n\n\n\n<p>Do not stop taking Morphine Kalceks unless you have agreed to do so with your doctor.\u00a0If you want to stop taking Morphine Kalceks, ask your doctor how to lower your\u00a0dose\u00a0slowly to avoid withdrawal symptoms.\u00a0Withdrawal symptoms can include body aches, tremors, diarrhea, abdominal pain, nausea,\u00a0flu-like symptoms, palpitations, and enlarged\u00a0pupils.\u00a0Psychological symptoms include an intense feeling of dissatisfaction, anxiety\/worry, and irritability.<\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor, pharmacist, or nurse<strong>.<\/strong><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p>Impaired respiratory function is a serious, less common side effect of morphine that may affect up to 1 in 100 people.&nbsp;If you have difficulty breathing, contact your doctor immediately for treatment of your impaired respiratory function.<\/p>\n\n\n\n<p>If you have a severe\u00a0allergic reaction\u00a0that makes it difficult to breathe or dizzy,\u00a0contact your doctor\u00a0<strong>immediately.<\/strong><\/p>\n\n\n\n<p><em>Common (may affect up to 1 in 10 people):<\/em>&nbsp;Drowsiness, dizziness, pupil reduction, nausea, vomiting, constipation, difficulty urinating, increased&nbsp;ADH&nbsp;release&nbsp;(&nbsp;a&nbsp;hormone&nbsp;).<\/p>\n\n\n\n<p><em>Uncommon (may affect up to 1 in 100 people):<\/em>\u00a0Depression, confusion, respiratory cramps, urinary tract or bile duct cramps,\u00a0itching, dizziness.<\/p>\n\n\n\n<p><em>Rare (may affect up to 1 in 1,000 people):<\/em>\u00a0Palpitations,\u00a0tachycardia, fainting, dizziness when getting up quickly, high\u00a0blood pressure, low\u00a0blood pressure, swelling of the feet and legs.<\/p>\n\n\n\n<p><em>Has been reported (occurs in an unknown number of users):\u00a0<\/em>Euphoria\u00a0(feeling of happiness), sleep, memory and concentration disorders, convulsions,\u00a0dry mouth,\u00a0hives, involuntary muscle twitching (myoclonus), increased pain sensitivity, sweating, withdrawal symptoms, or addiction (see the section, for symptoms 3: if you stop taking Morphine Kalceks).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Morphine Kalceks<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the carton after EXP.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>Store in the original package.&nbsp;Sensitive to light.<\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the pack and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<p>&#8211; The active substance is morphine hydrochloride.<\/p>\n\n\n\n<p>Morphine Kalceks contains 10 mg\/ml morphine hydrochloride equivalent to 7.6 mg\/ml morphine.<\/p>\n\n\n\n<p>The other ingredients are&nbsp;hydrochloric acid&nbsp;(&nbsp;pH&nbsp;adjustment), water for injections.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and contents of the pack<\/h2>\n\n\n\n<p>1 ml clear, colorless, or yellowish\u00a0solution for injection\u00a0in colorless\u00a0glass\u00a0ampoules (type I).<\/p>\n\n\n\n<p>Pack size: 10\u00a0ampoules.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p>AS Kalceks, Krustpils iela 53, Riga, LV-1057, Latvia<\/p>\n\n\n\n<p><strong>This medicinal product is authorized under the European Economic Area under the names:<\/strong><\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td>Sweden:<\/td><td>Morphine Kalceks, 10 mg\/ml,\u00a0solution\u00a0for injection<\/td><\/tr><tr><td>Netherlands:<\/td><td>Morphine Kalceks 10 mg\/ml solution for injection<\/td><\/tr><tr><td>Poland:<\/td><td>Morphine Kalceks<\/td><\/tr><tr><td>Czech Republic:<\/td><td>Morphine Kalceks<\/td><\/tr><tr><td>Portugal:<\/td><td>Morphine Kalceks<\/td><\/tr><tr><td>Slovakia:<\/td><td>Morphine Kalceks<\/td><\/tr><tr><td>Spain:<\/td><td>Morphine Kalceks 10 mg\/ml injectable solution<\/td><\/tr><tr><td>Czech Republic:<\/td><td>Morphine Kalceks<\/td><\/tr><tr><td>Portugal:<\/td><td>Morphine Kalceks<\/td><\/tr><tr><td>Slovakia:<\/td><td>Morphine Kalceks<\/td><\/tr><tr><td>Spain:<\/td><td>Morphine Kalceks 10 mg\/ml injectable solution EFG<\/td><\/tr><\/tbody><\/table><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>Morphine Kalceks contains the active substance morphine and is part of a group of medicines called natural opium alkaloids. This medicine is used to relieve severe pain, when other painkillers do not have sufficient effect.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,15580],"tags":[18024,18000,18020,18023,17996,17999,18021,17997,18022,17998],"class_list":["post-18327","post","type-post","status-publish","format-standard","hentry","category-medicines","category-m","tag-benefits-of-morphine-calcex","tag-benefits-of-morphine-hydrochloride","tag-morphine-calcex","tag-morphine-calcex-side-effects","tag-morphine-hydrochloride","tag-morphine-hydrochloride-side-effects","tag-what-is-morphine-calcex","tag-what-is-morphine-hydrochloride","tag-what-morphine-calcex-is-used-for","tag-what-morphine-hydrochloride-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/18327","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=18327"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/18327\/revisions"}],"predecessor-version":[{"id":18378,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/18327\/revisions\/18378"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=18327"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=18327"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=18327"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}