{"id":18114,"date":"2022-02-11T09:16:32","date_gmt":"2022-02-11T09:16:32","guid":{"rendered":"https:\/\/zeepedia.com\/?p=18114"},"modified":"2022-02-12T11:22:43","modified_gmt":"2022-02-12T11:22:43","slug":"mirvaso","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/mirvaso\/","title":{"rendered":"Mirvaso – Brimonidine uses, dose and side effects"},"content":{"rendered":"\n
3 mg \/ g gel brimonidine<\/p>\n\n\n\n
What Mirvaso is and what it is used for<\/h2>\n\n\n\n
Mirvaso contains the active substance brimonidine, which belongs to a group of medicines commonly referred to as “alpha-agonists”.<\/p>\n\n\n\n
Mirvaso is used on the skin of the face to treat redness due to rosacea in adult patients.<\/p>\n\n\n\n
Redness of the face due to rosacea is caused by heavy blood flow in the skin of the face, which is due to enlargement (enlargement) of the small blood vessels in the skin.<\/p>\n\n\n\n
When Mirvaso is used, it works by narrowing these blood vessels again, which reduces the excess blood flow and\u00a0redness.<\/p>\n\n\n\n
What you need to know before using Mirvaso<\/h2>\n\n\n\n
Do not use Mirvaso<\/h2>\n\n\n\n
if you are allergic to brimonidine or any of the other ingredients of this medicine (listed in section 6).<\/li>
to children under 2 years, as they may be at greater risk of side effects from the drugs that are absorbed through the skin.<\/li>
if you are taking certain medicines used to treat depression or Parkinson’s disease , including so-called monoamine oxidase inhibitors (MAOIs, eg selegiline , or moclobemide), tricyclic antidepressants (such as imipramine) or tetracyclic antidepressants (such as maprotiline, mianserin or mirtazapine). Using Mirvaso while you are taking these medicines may cause your blood pressure to drop .<\/li><\/ul>\n\n\n\n
Warnings and cautions<\/h2>\n\n\n\n
Talk to your doctor or pharmacist before using Mirvaso in particular about:<\/p>\n\n\n\n
the skin of your face is irritated or has open sores.<\/li>
you have problems with your heart or blood circulation.<\/li>
you have depression, decreased blood flow to the brain or heart, decreased blood pressure when standing, decreased blood flow in the hands, feet or skin, or Sj\u00f6gren’s syndrome (a chronic disease in which the body’s natural defenses – the immune system – attack the glands that produce moisture).<\/li>
you have or have previously had kidney or liver problems.<\/li>
you have undergone or are planning to undergo a laser treatment of the skin of your face.<\/li><\/ul>\n\n\n\n
It is important to start treatment with a small amount of\u00a0gel, increase the\u00a0dose\u00a0gradually but do not exceed the maximum\u00a0dose\u00a0of 1 gram (about 5 pea-sized clicks).\u00a0See also the instructions in “How to use Mirvaso”.<\/p>\n\n\n\n
Do not apply Mirvaso more than once a day and do not exceed the maximum daily dose of 1 gram (approximately 5 pea-sized clicks). See also the instructions in “How to use Mirvaso”.<\/p>\n\n\n\n
Exacerbated skin redness, the sudden feeling of heat often with\u00a0flushing\u00a0or\u00a0a burning sensation in the\u00a0skin<\/strong><\/p>\n\n\n\n
Up to 1 in 6 patients experience that their\u00a0redness\u00a0is worse when it returns compared to before treatment.\u00a0This usually occurs during the first two weeks of treatment and usually disappears if treatment is stopped, in most cases within a few days.\u00a0Before resuming treatment with Mirvaso\u00a0topical\u00a0gel, test it on a small area of \u200b\u200bthe face for a day when you have the opportunity to stay at home.\u00a0If you do not experience a worsening of\u00a0redness\u00a0or burning sensation, you can continue with the usual treatment (see section 3).<\/p>\n\n\n\n
If you experience an aggravated redness or if an unexpected redness occurs, stop treatment and consult a doctor.<\/p>\n\n\n\n
Talk to your doctor if any of the above apply to you, as this medicine may not be suitable for you.<\/p>\n\n\n\n
Children and young people<\/h2>\n\n\n\n
Do not give this medicine to children or adolescents under 18 years of age as the safety and efficacy have not been established for this age group. This is especially important for children under 2 years of age (see “Do not use Mirvaso”).<\/p>\n\n\n\n
Other medicines and Mirvaso<\/h2>\n\n\n\n
Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines, as these medicines may affect your treatment with Mirvaso, or Mirvaso may affect your treatment with these medicines.<\/p>\n\n\n\n
Do not use Mirvaso with\u00a0selegiline, moclobemide, imipramine, mianserin, or maprotiline, which are medicines that can be used for depression or\u00a0Parkinson’s disease, as this may lead to changes in the effectiveness of Mirvaso or may increase the risk of\u00a0side effects\u00a0such as a drop in blood pressure. Mirvaso).<\/p>\n\n\n\n
Also, tell your doctor if you are taking any of the following medicines:<\/p>\n\n\n\n
medicines used to treat pain, sleep disorders or anxiety disorders<\/li>
medicines used to treat mental disorders (chlorpromazine), used for hyperactivity (methylphenidate) or used for high blood pressure (reserpine).<\/li>
drugs that act in the same way in the body as Mirvaso (other alpha – agonists , eg clonidine; so-called alpha-blockers or alpha- antagonists , eg prazosin, isoprenaline , which are commonly used to treat high blood pressure , slow heartbeat or asthma ).<\/li>
cardiac glycosides (eg digoxin ) used to treat heart problems.<\/li>
antihypertensive drugs such as beta- blockers or calcium channel blockers (eg propranolol, amlodipine).<\/li><\/ul>\n\n\n\n
Talk to your doctor if any of the above apply to you, or if you are unsure.<\/p>\n\n\n\n
Mirvaso with alcohol<\/h2>\n\n\n\n
Tell your doctor if you drink alcohol regularly as it may affect your treatment with this medicine.<\/p>\n\n\n\n
Pregnancy and breastfeeding<\/h2>\n\n\n\n
The use of Mirvaso is not recommended during pregnancy.\u00a0This is because its effects on your unborn baby are unknown.\u00a0You should not use this medicine while breastfeeding, as it is not known if this medicine passes into breast milk.<\/p>\n\n\n\n
If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor for advice before using this medicine.<\/p>\n\n\n\n
Driving and using machines<\/h2>\n\n\n\n
Mirvaso has no significant effect on the ability to drive and use machines.<\/p>\n\n\n\n
Mirvaso contains:<\/h2>\n\n\n\n
methyl <\/strong>parahydroxybenzoate (E218)<\/strong> which may cause allergic reactions (possibly delayed).<\/li>
Propylene glycol <\/strong>(E1520)<\/strong> which may cause skin irritation.<\/li><\/ul>\n\n\n\n
How to use Mirvaso<\/h2>\n\n\n\n
Always use this medicine exactly as your doctor has told you. If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n
Important:<\/strong>\u00a0Mirvaso is for adults only and use on the skin of the face only.\u00a0Do not use this medicine on other parts of the body, especially moist body surfaces such as the eyes, mouth, nose, or vagina.<\/p>\n\n\n\n
Do not swallow.<\/p>\n\n\n\n
Keep Mirvaso\u00a0Gel\u00a0out of the reach of children.<\/p>\n\n\n\n
How to use Mirvaso<\/strong><\/p>\n\n\n\n
Mirvaso is recommended to be used on the face once a day.<\/p>\n\n\n\n
Start treatment with a small amount of gel (a pea-sized click) during the first week, as shown by your doctor or nurse.<\/p>\n\n\n\n
If your symptoms persist or only improve slightly, you can gradually increase the amount of\u00a0gel\u00a0after the first week.\u00a0Spread it evenly and evenly in a very thin layer in the way that your doctor or nurse has shown you.\u00a0You mustn’t take more than the maximum daily\u00a0dose\u00a0of 1 gram (5 pea-sized clicks applied to the entire face).<\/p>\n\n\n\n
Wash hands immediately after the application of this medicine.<\/p>\n\n\n\n
If your symptoms worsen during treatment with Mirvaso (increased redness or burning sensation), stop treatment and consult a doctor – see also section 2 “Warnings and precautions”.<\/p>\n\n\n\n
You need to avoid eyes, eyelids, lips, mouth, and the inside of the nose.\u00a0If a\u00a0gel\u00a0ends up in any of these areas, wash it off immediately with plenty of water.\u00a0If you experience an aggravated\u00a0redness\u00a0or burning sensation, stop using Mirvaso and consult a doctor if necessary.<\/p>\n\n\n\n
Do not apply any other dermatological or cosmetics immediately before the daily application of Mirvaso.\u00a0You should use such products only after applying Mirvaso has dried.<\/p>\n\n\n\n
Be careful when opening the tube\/pump for the first time so that you do not spill more\u00a0gel\u00a0than necessary.\u00a0If this happens, discard the excess\u00a0gel\u00a0so that you do not apply more than the recommended\u00a0dose.\u00a0See the section “How to use Mirvaso” above<\/p>\n\n\n\n
To open the tube with a child-resistant lid:<\/strong><\/p>\n\n\n\n
To avoid spillage, do not squeeze the tube while opening or closing it.<\/p>\n\n\n\n
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