drugs that can affect the heart rhythm<\/strong> such as certain antibiotics and certain antipsychotic drugs.<\/li><\/ul>\n\n\n\nMirtazapine Orion with food and alcohol<\/h2>\n\n\n\n
You may become drowsy if you drink alcohol while taking Mirtazapine Orion.<\/p>\n\n\n\n
Do not drink alcohol while using Mirtazapine Orion.<\/p>\n\n\n\n
You can take Mirtazapine Orion with or without food.<\/p>\n\n\n\n
Pregnancy and breastfeeding<\/h2>\n\n\n\n
If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<\/p>\n\n\n\n
Limited experience with Mirtazapine Orion in pregnant women does not indicate an increased risk.\u00a0However, caution should be exercised when used during pregnancy.\u00a0If you are taking Mirtazapine Orion until, or just before delivery, your baby should be checked for any\u00a0side effects.<\/p>\n\n\n\n
When similar drugs (\u00a0SSRIs\u00a0) are used during pregnancy, the risk of a serious condition called\u00a0persistent\u00a0pulmonary\u00a0hypertension\u00a0in the newborn (PPHN) may increase.\u00a0This condition causes the baby to breathe faster and look blue.\u00a0The symptoms usually appear within 24 hours of the baby’s born.\u00a0If this affects your baby, contact a midwife or doctor immediately.<\/p>\n\n\n\n
Driving and using machines<\/h2>\n\n\n\n
Mirtazapine Orion may affect your concentration or reactivity. Make sure your ability has not been affected before driving or using machines. If your doctor has prescribed Mirtazapine Orion to a patient under 18 years of age, make sure that concentration or attention is not affected before the person goes out into the traffic (eg by bicycle).<\/p>\n\n\n\n
You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects.\u00a0Descriptions of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n
Mirtazapine Orion contains lactose<\/h2>\n\n\n\n
Mirtazapine Orion tablets contain\u00a0lactose monohydrate\u00a0102 mg (15 mg tablet), 204 mg (30 mg tablet), and 306 mg (45 mg tablet).\u00a0If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.<\/p>\n\n\n\n
How to take Mirtazapine Orion<\/h2>\n\n\n\n
Always take this medicine exactly as your doctor or pharmacist has told you. Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n
How much to take<\/strong><\/p>\n\n\n\nThe recommended starting dose is 15 or 30 mg per day.\u00a0Your doctor may increase the\u00a0dose\u00a0one after a few days to the amount that is best for you (between 15 and 45 mg per day).\u00a0Dose\u00a0one is usually the same for all age groups.\u00a0If you are elderly or have a kidney or liver disease, your doctor may need to adjust your\u00a0dose.<\/p>\n\n\n\n
When to take Mirtazapine Orion<\/strong><\/p>\n\n\n\nTake Mirtazapine Orion at the same time each day.<\/p>\n\n\n\n
It is best to take Mirtazapine Orion as a single dose before going to bed. However, your doctor may suggest that you split a dose of Mirtazapine Orion – once in the morning and once before going to bed. The higher dose one should take before going to bed. Take the tablets by mouth. Swallow your prescribed dose of Mirtazapine Orion without chewing on the tablet, with water or juice.<\/p>\n\n\n\n
When can you expect to start feeling better?<\/strong><\/p>\n\n\n\nIt usually takes 1-2 weeks before Mirtazapine Orion starts working and after 2-4 weeks you may start to feel better.<\/p>\n\n\n\n
It is important during the first weeks of treatment that you talk to your doctor about the effects of Mirtazapine Orion:<\/p>\n\n\n\n
- talk to your doctor 2 to 4 weeks after you start taking Mirtazapine Orion about the effect of the treatment.<\/li><\/ul>\n\n\n\n
If you still do not feel better, your doctor may give you a higher\u00a0dose.\u00a0In that case, talk to your doctor again after another 2 to 4 weeks.\u00a0You should usually take Mirtazapine Orion until your depressive symptoms have been gone for 4-6 months.<\/p>\n\n\n\n
If you take more Mirtazapine Orion than you should<\/h2>\n\n\n\n
The most likely signs of an overdose of Mirtazapine Orion (without other medicines or alcohol) are\u00a0drowsiness, confusion,<\/strong> and an increased heart rate.\u00a0The symptoms of a possible overdose can be changes in heart rhythm (fast, irregular heartbeat) and\/or fainting, which can be symptoms of a life-threatening condition called\u00a0torsades de pointes.<\/p>\n\n\n\nIf you forget to take Mirtazapine Orion<\/h2>\n\n\n\n
If you are going to take your dose once a day<\/strong><\/p>\n\n\n\n- Do not take a double dose to make up for a forgotten dose . Take your next dose at the usual time.<\/li><\/ul>\n\n\n\n
If you are going to take your dose twice a day<\/strong><\/p>\n\n\n\n- If you forget to take your morning dose, take it with your evening dose.<\/li>
- if you forget to take your evening dose, do not take it with your morning dose the next day, just skip it and continue with your usual morning and evening doses.<\/li>
- if you have missed both doses , do not try to compensate for the missed doses . Skip both doses and continue the next day with your usual morning and evening doses.<\/li><\/ul>\n\n\n\n
If you stop taking Mirtazapine Orion<\/h2>\n\n\n\n
Only stop taking Mirtazapine Orion if you have agreed with your doctor.<\/p>\n\n\n\n
If you quit too soon, your depression may return. When you start to feel better, talk to a doctor. Your doctor will decide when you can stop treatment.<\/p>\n\n\n\n
Do not suddenly stop taking Mirtazapine Orion, even if your depression has subsided.\u00a0If you stop taking Mirtazapine Orion suddenly, you may feel nauseous, dizzy, upset, anxious, or have a headache.\u00a0These symptoms can be avoided if you step down gradually.\u00a0Your doctor will tell you how to reduce the\u00a0dose\u00a0gradually.<\/p>\n\n\n\n
If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n
Possible side effects<\/h2>\n\n\n\n
Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n
If you experience any of the following serious\u00a0side effects, stop taking mirtazapine and contact your doctor immediately.<\/strong><\/p>\n\n\n\nUncommon<\/strong> ( may affect up to 1 in 100 people<\/em> ):<\/p>\n\n\n\n- feeling elated or feeling “high” (mania).<\/li><\/ul>\n\n\n\n
Rare<\/strong> ( may affect up to 1 in 1,000 people<\/em> ):<\/p>\n\n\n\n- yellowing of the whites of the eyes or the skin; it may be a sign of liver dysfunction (jaundice).<\/li><\/ul>\n\n\n\n
Has been reported<\/strong> ( occurs in an unknown number of users<\/em> ):<\/p>\n\n\n\n- signs of infection such as sudden unexplained high fever, sore throat and sore mouth. ( agranulocytosis ). In rare cases, mirtazapine may interfere with the production of blood cells (bone marrow depression). Some people become more susceptible to infection because mirtazapine can cause a temporary lack of white blood cells ( granulocytopenia ). In rare cases, mirtazapine may also cause a lack of red and white blood cells as well as platelets ( aplastic anemia ), a lack of platelets ( thrombocytopenia ) or an increase in white blood cells ( eosinophilia) .).<\/li>
- epileptic seizures (seizures)<\/li>
- a combination of symptoms such as unexplained fever, sweating, increased heart rate, diarrhea, (uncontrollable) muscle contractions, chills, overactive reflexes, restlessness, mood swings and unconsciousness and increased salivation. In very rare cases, this may be a sign of serotonergic syndrome.<\/li>
- thoughts of wanting to hurt yourself or commit suicide<\/li>
- severe skin reactions
- reddish spots on the torso that resemble targets or are round, often with blisters in the middle; flaking skin; sores in the oral cavity, throat, nose, genitals and eyes. These severe skin rashes may be preceded by fever and flu-like symptoms (Stevens-Johnson syndrome, toxic epidermal necrolysis ).<\/li>
- widespread skin rash, high body temperature and enlarged lymph nodes (DRESS syndrome or drug hypersensitivity syndrome).<\/li><\/ul><\/li><\/ul>\n\n\n\n
Other possible side effects of mirtazapine are:<\/strong><\/p>\n\n\n\nVery common<\/strong> ( may affect more than 1 user in 10<\/em> ):<\/p>\n\n\n\n- increased appetite and weight gain<\/li>
- drowsiness or drowsiness<\/li>
- headache<\/li>
- dry mouth .<\/li><\/ul>\n\n\n\n
Common<\/strong> ( may affect up to 1 in 10 people<\/em> ):<\/p>\n\n\n\n- decreased alertness<\/li>
- dizziness<\/li>
- shaking or trembling<\/li>
- nausea<\/li>
- diarrhea<\/li>
- vomiting<\/li>
- constipation<\/li>
- skin rash or eczema (exanthema)<\/li>
- joint pain ( arthralgia ) or muscle ( myalgia )<\/li>
- back pain<\/li>
- feeling dizzy or fainting when you get up suddenly ( orthostatic hypotension )<\/li>
- swelling (especially ankles and feet) due to fluid retention ( edema )<\/li>
- fatigue<\/li>
- vivid dreams<\/li>
- confusion<\/li>
- feelings of anxiety<\/li>
- sleeping problems<\/li>
- memory problems, which in most cases went back when treatment was stopped. <\/li><\/ul>\n\n\n\n
Uncommon<\/strong> ( may affect up to 1 in 100 people<\/em> ):<\/p>\n\n\n\n- abnormal sensation in the skin, e.g. burning, stinging, tickling or irritating ( paresthesia )<\/li>
- ant crawls in the legs (restless legs)<\/li>
- fainting ( syncope )<\/li>
- feeling of numbness in the mouth ( oral hypesthesia )<\/li>
- low blood pressure<\/li>
- nightmares<\/li>
- feeling of upset<\/li>
- hallucinations<\/li>
- strong need to move.<\/li><\/ul>\n\n\n\n
Rare<\/strong> ( may affect up to 1 in 1,000 people<\/em> ):<\/p>\n\n\n\n- muscle twitching or contractions ( myoclonus )<\/li>
- aggression<\/li>
- abdominal pain and nausea, this may indicate inflammation of the pancreas ( pancreatitis ).<\/li><\/ul>\n\n\n\n
Has been reported<\/strong> ( occurs in an unknown number of users<\/em> ):<\/p>\n\n\n\n- abnormal sensation in the mouth (oral paresthesia )<\/li>
- swelling of the mouth ( edema of the mouth)<\/li>
- swelling in the body (general edema )<\/li>
- local swelling (local edema )<\/li>
- hyponatremia (low level of sodium in the blood)<\/li>
- improper secretion of antidiuretic hormone<\/li>
- severe skin reactions (bullous dermatitis , erythema multiforme)<\/li>
- go to sleep (somnambulism)<\/li>
- speech difficulties<\/li>
- increased levels of creatine kinase in the blood<\/li>
- difficulty urinating ( urinary retention )<\/li>
- muscle pain, stiffness and \/ or weakness<\/li>
- dark or discolored urine ( rhabdomyolysis )<\/li>
- elevated levels of the hormone et prolactin in the blood ( hyperprolactinemia , including symptoms of enlarged breasts and \/ or milk flow from the breasts)<\/li>
- prolonged painful erection of the penis.<\/li><\/ul>\n\n\n\n
Additional side effects in children and adolescents<\/h2>\n\n\n\n
In children under 18 years of age, the following\u00a0side effects\u00a0were common in clinical trials: significant weight gain, hives, and increased\u00a0triglycerides\u00a0(a type of blood fat) in the blood.<\/p>\n\n\n\n
How to store Mirtazapine Orion<\/h2>\n\n\n\n
Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n
Do not use this medicine after the expiry date which is stated on the carton. The expiration date is the last day of the specified month.<\/p>\n\n\n\n
No special storage instructions.<\/p>\n\n\n\n
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.<\/p>\n\n\n\n
Contents of the pack and other information<\/h2>\n\n\n\nContent declaration<\/h2>\n\n\n\n- The active substance is mirtazapine. Each tablet contains 15 mg, 30 mg or 45 mg of mirtazapine.<\/li>
- The other ingredients are:
Tablet core<\/em> : lactose monohydrate , corn starch, hydroxypropylcellulose, low-substituted hydroxypropylcellulose, magnesium stearate and anhydrous colloidal silica.
Tablet coating<\/em> : hypromellose, hydroxypropylcellulose and titanium dioxide (E171).<\/li><\/ul>\n\n\n\nCoating of Mirtazapine Orion 15 mg film-coated tablets also contain yellow iron oxide (E172), 30 mg tablet coating contains yellow, red, and black iron oxide (E172).<\/p>\n\n\n\n
What the medicine looks like and contents of the pack<\/h2>\n\n\n\n
15 mg film-coated tablet: Yellow, biconvex capsule-shaped, film-coated tablet with a scoreline between an embossed 1 and 5 on one side and ‘MI’ embossed on the other side.\u00a0The tablet is 9.1 mm x 4.6 mm.<\/p>\n\n\n\n
30 mg film-coated tablet: Reddish-brown, biconvex, capsule-shaped, film-coated tablet with a scoreline between an embossed 3 and 0 on one side and ‘MI’ embossed on the other side.\u00a0The tablet is 14.1 mm x 6.1 mm.<\/p>\n\n\n\n
45 mg film-coated tablet: A white, biconvex, capsule-shaped, film-coated tablet with ’45’ embossed on one side and ‘MI’ embossed on the other side.\u00a0The tablet is 14.1 mm x 7.1 mm.<\/p>\n\n\n\n
15 mg and 30 mg tablets can be divided into two equal\u00a0doses.<\/p>\n\n\n\n
The tablets are available in blister packs of 28, 30, 98, or 100 tablets and HDPE cans of 100 and 250 tablets.<\/p>\n\n\n\n
Not all pack sizes may be marketed.<\/p>\n\n\n\n
Marketing Authorisation Holder<\/h2>\n\n\n\n
Orion Corporation<\/p>\n\n\n\n
Orionintie 1<\/p>\n\n\n\n
FI-02200 Espoo<\/p>\n\n\n\n
Finland<\/p>\n\n\n\n
Manufacturer<\/strong><\/p>\n\n\n\nOrion Corporation Orion Pharma<\/p>\n\n\n\n
Orionintie 1<\/p>\n\n\n\n
FI-02200 Espoo<\/p>\n\n\n\n
Finland<\/p>\n\n\n\n
Orion Corporation Orion Pharma<\/p>\n\n\n\n
Joensuunkatu 7<\/p>\n\n\n\n
FI-24100 Salo<\/p>\n\n\n\n
Finland<\/p>\n\n\n\n
For further information on this medicine, please contact your local representative:<\/strong><\/p>\n\n\n\nOrion Pharma AB, Danderyd<\/p>\n\n\n\n
medinfo@orionpharma.com<\/p>\n","protected":false},"excerpt":{"rendered":"
Mirtazapine Orion belongs to a group of medicines called antidepressants .<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,15580],"tags":[17682,17813,17677,17808,17812,17811,17681,17680,17678,17809,17679,17810],"class_list":["post-18109","post","type-post","status-publish","format-standard","hentry","category-medicines","category-m","tag-benefits-of-mirtazapine","tag-benefits-of-mirtazapine-orion","tag-mirtazapine","tag-mirtazapine-orion","tag-mirtazapine-orion-side-effects","tag-mirtazapine-orion-tablet","tag-mirtazapine-side-effects","tag-mirtazapine-tablet","tag-what-is-mirtazapine","tag-what-is-mirtazapine-orion","tag-what-mirtazapine-is-used-for","tag-what-mirtazapine-orion-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/18109","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=18109"}],"version-history":[{"count":5,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/18109\/revisions"}],"predecessor-version":[{"id":18173,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/18109\/revisions\/18173"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=18109"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=18109"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=18109"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}