100 mg hard capsules
miglustat<\/p>\n\n\n\n
Miglustat Bluefish contains the active substance miglustat, which belongs to a group of medicines that affect\u00a0metabolism.\u00a0It is used to treat two diseases.<\/p>\n\n\n\n
Miglustat Bluefish is used to treat mild to moderate Gaucher type 1 disease in adults.<\/strong><\/p>\n\n\n\n For\u00a0Gaucher\u00a0type 1 disease, a substance called glucosylceramide is not removed from your body.\u00a0It begins to be stored in certain cells that belong to the body’s immune system.\u00a0This can lead to liver and spleen enlargement, changes in the blood, and skeletal disease.<\/p>\n\n\n\n Gaucher’s type 1 disease is normally treated with enzyme replacement therapy. Miglustat Bluefish is used only if the patient is not considered suitable for treatment with enzyme replacement therapy.<\/p>\n\n\n\n Miglustat Bluefish is also used to treat the growing neurological symptoms of Niemann-Pick type C in adults and children<\/strong><\/p>\n\n\n\n If you have Niemann-Pick type C disease, fats, such as glycosphingolipids, are stored in your brain cells.\u00a0This can lead to disturbances in neurological functions such as slow eye movements, balance, swallowing ability, memory, and to seizures.<\/p>\n\n\n\n Miglustat Bluefish acts by inhibiting an enzyme called “glucosylceramide synthetase”, which is responsible for the first step in the production of most glycosphingolipids.<\/p>\n\n\n\n Miglustat contained in Miglustat Bluefish may also be approved for the treatment of other diseases not mentioned in this leaflet.\u00a0Ask your doctor, pharmacist, or other healthcare professionals if you have any further questions, and always follow their instructions.<\/p>\n\n\n\n Talk to your doctor or pharmacist before taking Miglustat Bluefish<\/p>\n\n\n\n Your doctor will perform the following checks before and during treatment with Miglustat Bluefish:<\/p>\n\n\n\n The reason for these controls is that some patients have had tingling or numbness in their hands and feet or lost weight during treatment with Miglustat Bluefish. The checks make it easier for the doctor to determine if these problems are due to your illness or something you have had in the past, or if they are due to side effects of Miglustat Bluefish (for more information see section 4).<\/p>\n\n\n\n If you get diarrhea, your doctor may ask you to change your diet so that you reduce your intake of milk sugar, and carbohydrates such as sucrose (regular sugar).\u00a0Your doctor may also ask you not to take Miglustat Bluefish with food.\u00a0In some cases, your doctor may temporarily lower your\u00a0dose\u00a0or prescribe a medicine for diarrhea (such as loperamide).\u00a0If your diarrhea does not respond to these measures, or if you have any other stomach problems, consult your doctor.\u00a0In this case, your doctor may decide on further investigations.<\/p>\n\n\n\n Male patients should use reliable contraception during treatment with Miglustat Bluefish and for 3 months after stopping treatment.<\/p>\n\n\n\n Do not give this medicine to children and adolescents (under 18 years of age) with Gaucher type 1 disease because it is not known if it works against that disease.<\/p>\n\n\n\n Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.<\/p>\n\n\n\n Tell your doctor if you are taking medicines containing imiglucerase, which are sometimes used at the same time as Miglustat Bluefish. They can lower the amount of Miglustat Bluefish in your body.<\/p>\n\n\n\n You should not take Miglustat Bluefish if you are pregnant or planning to become pregnant.\u00a0Your doctor can give you more information.\u00a0You must use safe contraception when taking Miglustat Bluefish.\u00a0Do not breastfeed while taking Miglustat Bluefish.<\/p>\n\n\n\n Male patients should use reliable contraception during treatment with Miglustat Bluefish and 3 months after stopping treatment.<\/p>\n\n\n\n If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<\/p>\n\n\n\n Miglustat Bluefish can make you feel dizzy. Do not drive or use any tools or machines if you feel dizzy.<\/p>\n\n\n\n You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects.\u00a0The description of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n This medicine contains less than 1 mmol (23 mg) sodium per 100 mg capsules, ie essentially ‘sodium-free’.<\/p>\n\n\n\n Always take this medicine exactly as your doctor has told you. Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n For children under the age of 12 who have Niemann-Pick type C disease, your doctor will adjust the dose one.<\/p>\n\n\n\n If you have kidney problems, you may receive a lower starting dose.\u00a0Your doctor may reduce your\u00a0dose\u00a0e.g.\u00a0to a hard capsule (100 mg) once or twice a day if you suffer from diarrhea during treatment with Miglustat Bluefish (see section 4).\u00a0Your doctor will tell you how long you will be treated.<\/p>\n\n\n\n Miglustat Bluefish can be taken with or without food. You should swallow the whole capsule with a glass of water.<\/p>\n\n\n\n Miglustat Bluefish has been used in\u00a0clinical trials\u00a0at\u00a0doses\u00a0ten times higher than the recommended\u00a0dose: this caused a decrease in the number of\u00a0white blood cells\u00a0and other\u00a0side effects\u00a0similar to those described in section 4.<\/p>\n\n\n\n Take the next hard capsule at the usual time.\u00a0Do not take a double\u00a0dose\u00a0to make up for a forgotten\u00a0dose.<\/p>\n\n\n\n Do not stop taking Miglustat Bluefish without talking to your doctor.<\/p>\n\n\n\n If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n Most serious side effects:<\/em><\/p>\n\n\n\n Some patients have experienced tingling or numbness in the hands and feet (common). <\/strong>This may be a sign of peripheral neuropathy due to side effects of Miglustat Bluefish or due to pre-existing conditions. Your doctor will perform some checks before and during treatment with Miglustat Bluefish to evaluate this (see section 2).<\/p>\n\n\n\n If you experience any of these symptoms, consult your doctor as soon as possible.<\/strong><\/p>\n\n\n\n If you experience mild tremors<\/strong>, usually in\u00a0your hands, consult your doctor\u00a0as soon as possible.\u00a0These tremors usually disappear without the need to interrupt treatment.\u00a0Sometimes your doctor will need to reduce the\u00a0dose\u00a0one or discontinue treatment with Miglustat Bluefish for you to get rid of the tremors.<\/p>\n\n\n\n Very common <\/strong> (may affect more than 1 user in 10):<\/em><\/p>\n\n\n\n The most common\u00a0side effects\u00a0are diarrhea, gas, abdominal (stomach) pain, weight loss, and decreased appetite.\u00a0Do not worry\u00a0if you lose any weight<\/strong>\u00a0when starting treatment with Miglustat Bluefish.\u00a0You usually stop losing weight when the treatment continues.<\/p>\n\n\n\n Common <\/strong> (may affect up to 1 in 10 people): <\/em><\/p>\n\n\n\n Common\u00a0side effects\u00a0of treatment include headache, dizziness,\u00a0paresthesia\u00a0(tingling or numbness), abnormal coordination, hypoesthesia (decreased sensation), acid regurgitation (heartburn), nausea, constipation and vomiting, swelling or discomfort from the abdomen (stomach), and thrombocytopenia (decreased\u00a0platelet\u00a0level\u00a0).\u00a0The neurological symptoms and thrombocytopenia may be caused by the underlying disease.<\/p>\n\n\n\n Other possible\u00a0side effects\u00a0are muscle spasms or weakness, fatigue, chills and general malaise, depression, difficulty sleeping, forgetfulness, and decreased\u00a0libido.<\/p>\n\n\n\n Most patients experience one or more of these\u00a0side effects, usually at the beginning of treatment or periodically during treatment.\u00a0In most cases, the\u00a0side effects\u00a0are mild and disappear fairly quickly.\u00a0If any of these\u00a0side effects\u00a0occur, consult your doctor.\u00a0He or she can then reduce the dose of Miglustat Bluefish or suggest other medications that can help reduce the\u00a0side effects.<\/p>\n\n\n\n Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n Do not use this medicine after the expiry date which is stated on the carton after \u201cEXP\u201d. The expiration date is the last day of the specified month.<\/p>\n\n\n\n Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.<\/p>\n\n\n\n The active substance is miglustat. Each capsule contains 100 mg miglustat.<\/p>\n\n\n\n Other ingredients are:<\/p>\n\n\n\n Capsule contents: sodium starch glycolate type A, povidone, magnesium stearate<\/p>\n\n\n\n Capsule shell: titanium dioxide (E171), gelatin<\/p>\n\n\n\n White hard gelatin capsules, filled with homogeneous white to off-white granules in perforated Aclar-Alu blisters (PVC \/ PE \/ PCTFE-Alu blisters).<\/p>\n\n\n\n Miglustat Bluefish 100 mg hard capsules are available in packs of 84 hard capsules.<\/p>\n\n\n\n Manufacturer<\/strong><\/p>\n\n\n\n GL Pharma GmbH<\/p>\n\n\n\n Schlossplatz 1, Lannach 8502<\/p>\n\n\n\n Austria<\/p>\n\n\n\n This medicinal product is authorized under the European Economic Area under the names:<\/strong><\/p>\n\n\n\n Miglustat Bluefish contains the active substance miglustat, which belongs to a group of medicines that affect metabolism . It is used to treat two diseases.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,15580],"tags":[17547,17557,17542,17553,17556,17546,17543,17554,17555,17544],"class_list":["post-17963","post","type-post","status-publish","format-standard","hentry","category-medicines","category-m","tag-benefits-of-miglustat","tag-benefits-of-miglustat-bluefish","tag-miglustat","tag-miglustat-bluefish","tag-miglustat-bluefish-side-effects","tag-miglustat-side-effects","tag-what-is-miglustat","tag-what-is-miglustat-bluefish","tag-what-miglustat-bluefish-is-used-for","tag-what-miglustat-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/17963","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=17963"}],"version-history":[{"count":3,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/17963\/revisions"}],"predecessor-version":[{"id":17986,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/17963\/revisions\/17986"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=17963"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=17963"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=17963"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}What you need to know before you take Miglustat Bluefish<\/h2>\n\n\n\n
Do not take Miglustat Bluefish<\/h2>\n\n\n\n
Warnings and cautions<\/h2>\n\n\n\n
Children and young people<\/h2>\n\n\n\n
Other medicines and Miglustat Bluefish<\/h2>\n\n\n\n
Pregnancy, breastfeeding and fertility<\/h2>\n\n\n\n
Driving and using machines<\/h2>\n\n\n\n
Miglustat Bluefish contains sodium<\/h2>\n\n\n\n
How to take Miglustat Bluefish<\/h2>\n\n\n\n
If you take more Miglustat Bluefish than you should<\/h2>\n\n\n\n
If you forget to take Miglustat Bluefish<\/h2>\n\n\n\n
If you stop taking Miglustat Bluefish<\/h2>\n\n\n\n
Possible side effects<\/h2>\n\n\n\n
How to store Miglustat Bluefish<\/h2>\n\n\n\n
Contents of the pack and other information<\/h2>\n\n\n\n
Content declaration<\/h2>\n\n\n\n
What the medicine looks like and contents of the pack<\/h2>\n\n\n\n
Marketing Authorisation Holder<\/h2>\n\n\n\n
Germany<\/td> Miglustat Bluefish 100 mg Heart Capsule<\/td><\/tr> Denmark<\/td> Miglustat Bluefish<\/td><\/tr> France<\/td> Miglustat Bluefish 100 mg g\u00e9lules<\/td><\/tr> Norway<\/td> Miglustat Bluefish 100 mg hard capsules<\/td><\/tr> Sweden<\/td> Miglustat Bluefish 100 mg hard capsules<\/td><\/tr><\/tbody><\/table><\/figure>\n","protected":false},"excerpt":{"rendered":"