1 mg \/ ml resp. 5 mg \/ ml solution for injection
midazolam<\/p>\n\n\n\n
Midazolam Panpharma belongs to a group of medicines called\u00a0benzodiazepines.\u00a0It is a short-acting drug used to induce\u00a0sedation\u00a0(a state of calm, drowsiness, or sleep) and reduces anxiety, muscle tension.\u00a0It has antispasmodic effects and causes memory loss (anterograde\u00a0amnesia\u00a0).<\/p>\n\n\n\n
This medicine is used:<\/p>\n\n\n\n
Midazolam contained in Midazolam Panpharma may also be approved for the treatment of other conditions not mentioned in this product information.\u00a0Ask your doctor, pharmacist, or another healthcare professional if you have any further questions, and always follow their instructions.<\/p>\n\n\n\n
Take special care with Midazolam Panpharma<\/strong><\/p>\n\n\n\n This medicine should only be administered by an experienced doctor in a ward fully equipped to monitor and support respiratory and cardiac function and by people who are specially trained to recognize and treat expected\u00a0side effects.<\/p>\n\n\n\n Administration of midazolam may reduce the contractions of the heart and cause respiratory arrest.\u00a0Serious\u00a0side effects\u00a0on the heart and airways have been reported in rare cases.\u00a0These\u00a0side effects\u00a0have included decreased breathing, respiratory and\/or cardiac arrest.\u00a0To avoid such events,\u00a0the injection\u00a0should be given slowly and\u00a0the dose\u00a0should be as low as possible.<\/p>\n\n\n\n Particular caution should be exercised when using Midazolam Panpharma in infants or children. Tell your doctor if your child has a heart defect. Your child will be closely monitored and dose one will be adjusted specifically.<\/p>\n\n\n\n Patients under 6 months of age who receive sedation in the intensive care unit are more likely to develop respiratory problems, so they will be dosed gradually and their respiration and oxygen levels will be observed.<\/p>\n\n\n\n When midazolam is given as a sedative and hypnotic before initiating anesthesia, you will be closely monitored for how you react and to ensure that you receive the correct\u00a0dose, as sensitivity varies depending on the patient.<\/p>\n\n\n\n The use of midazolam is not recommended for newborns and children up to 6 months of age.<\/p>\n\n\n\n Unexpected reactions and memory loss regarding new events (anterograde amnesia ) have been reported with midazolam (see section 4, \u201cPossible side effects\u201d).<\/p>\n\n\n\n Tell your doctor if you:<\/p>\n\n\n\n Withdrawal symptoms<\/strong><\/p>\n\n\n\n Benzodiazepines, such as midazolam, may make you addicted if used for a long time (for example in intensive care).\u00a0This means that if you suddenly stop treatment or reduce the\u00a0dose\u00a0too quickly, you may get withdrawal symptoms. Long-term<\/strong> After a long period of treatment (such as in an intensive care unit), the following withdrawal symptoms may occur headache, muscle pain, anxiety, tension, restlessness, confusion, irritability, insomnia, mood swings, hallucinations, and seizures.\u00a0Your doctor will gradually reduce your\u00a0dose\u00a0to prevent these effects from affecting you.<\/p>\n\n\n\n Tell your doctor if you are taking, have recently taken, or might take any other medicines.<\/p>\n\n\n\n This is extremely important, as concomitant use of more than one medicine may enhance or weaken the effects of the medicines.\u00a0For example, the effects of midazolam may be enhanced by medicines such as sedatives, hypnotics, antidepressants, narcotic painkillers (very strong painkillers), anesthetics, and certain anti-allergy\u00a0medicines (\u00a0antihistamines\u00a0).<\/p>\n\n\n\n Concomitant use of Midazolam Panpharma with opioids (strong painkillers, opioid treatment drugs, and certain cough medicines) increases the risk of drowsiness, difficulty breathing (\u00a0respiratory depression\u00a0),\u00a0coma\u00a0and may be life-threatening.\u00a0Due to this, concomitant use should only be considered when other treatment options are not possible.<\/p>\n\n\n\n If your doctor prescribes Midazolam Panpharma at the same time as an opioid medicine, dose one and the duration of treatment should be limited by your doctor.<\/p>\n\n\n\n Tell your doctor if you are taking any opioid medication and carefully follow your doctor’s dosing recommendations. It may be helpful to inform friends or relatives about being aware of the signs and symptoms listed above. Contact a doctor if you experience any of these symptoms.<\/p>\n\n\n\n The effects of midazolam given in a vein (\u00a0intravenously\u00a0) may also be increased with medicines such as antifungal medicines (\u00a0ketoconazole, voriconazole,\u00a0fluconazole, itraconazole, posaconazole), medicines for bacterial infections (erythromycin, clarithromycin), medicines used to treat high\u00a0blood pressure\u00a0(\u00a0diltiazem\u00a0), to treat\u00a0HIV\u00a0(saquinavir and other\u00a0HIV\u00a0protease inhibitors\u00a0) and to\u00a0lower cholesterol (atorvastatin).<\/p>\n\n\n\n The effects of midazolam given in a vein (\u00a0intravenously\u00a0) can be reduced by medicines used to treat\u00a0infections\u00a0caused by mycobacteria such as\u00a0tuberculosis\u00a0(rifampicin, carbamazepine,\u00a0phenytoin\u00a0), as well as by\u00a0St. John’s wort, a (traditional) herbal medicine.<\/p>\n\n\n\n Alcohol may increase the sedative effects of midazolam and should therefore be avoided.<\/p>\n\n\n\n If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor for advice before using this medicine.<\/p>\n\n\n\n Midazolam may pass into breast milk and if you are breastfeeding, do not do so for 24 hours after receiving this medicine.<\/p>\n\n\n\n This medicine may make you drowsy, forgetful or affect your concentration and coordination. This can affect your ability to perform more difficult tasks, e.g. to drive a car or use machines. After receiving midazolam, do not drive or use machines until you have fully recovered. Your doctor will tell you when you can do it again. After the treatment, you should always be accompanied home by a responsible adult.<\/p>\n\n\n\n You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened vigilance.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects.\u00a0Descriptions of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n This medicine contains less than 1 mmol\u00a0sodium\u00a0(23 mg) per\u00a0vial\u00a0or\u00a0vial, ie essentially ‘sodium-free’.<\/p>\n\n\n\n Midazolam Panpharma should only be given by experienced doctors in a fully equipped ward to monitor and support respiratory and cardiac function and by people who are specially trained to recognize and treat expected\u00a0side effects.<\/p>\n\n\n\n Dosage\u00a0and how the medicine is given<\/strong> If you are going to get strong painkillers, you will get these first and then get Midazolam Panpharma in the dose that is tailored specifically for you.<\/p>\n\n\n\n Midazolam Panpharma is given slowly, as an\u00a0injection\u00a0into a vein (\u00a0intravenously\u00a0), as a drip (\u00a0infusion\u00a0), as an\u00a0injection\u00a0into a muscle (\u00a0intramuscularly\u00a0), or via the rectum.<\/p>\n\n\n\n It is unlikely that you will get an overdose.\u00a0Your medicine will be given by a doctor. Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n Seek medical attention immediately if you get any of the following symptoms. They can be life-threatening and you may need urgent medical attention:<\/strong><\/p>\n\n\n\n Life-threatening\u00a0side effects\u00a0are more likely to occur in adults over 60 years of age and in those who already have difficulty breathing or heart problems, especially if\u00a0the injection\u00a0is given too quickly or in high\u00a0doses.<\/p>\n\n\n\n For a list of side effects associated with midazolam discontinuation, see section 2 of this leaflet.<\/u><\/strong><\/p>\n\n\n\n Other possible side effects:<\/strong><\/p>\n\n\n\n Immune system:<\/strong><\/p>\n\n\n\n Impact on behavior:<\/strong><\/p>\n\n\n\n Muscle problem:<\/strong><\/p>\n\n\n\n Mental problems and problems in the nervous system:<\/strong><\/p>\n\n\n\n Problems with heart and blood circulation:<\/strong><\/p>\n\n\n\n Breathing difficulties:<\/strong><\/p>\n\n\n\n Stomach, intestinal and oral problems:<\/strong><\/p>\n\n\n\n Skin problems:<\/strong><\/p>\n\n\n\n Injection site problems:<\/strong><\/p>\n\n\n\n Generally:<\/strong><\/p>\n\n\n\n Elderly patients:<\/strong><\/p>\n\n\n\n Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n Do not use this medicine after the expiry date which is stated on the ampoule\/vial label after EXP.<\/p>\n\n\n\n The expiration date is the last day of the specified month.<\/p>\n\n\n\n Keep the ampoule or vial in the outer carton. Sensitive to light.<\/p>\n\n\n\n After dilution, the solution must be used immediately.\u00a0If the solution is not used immediately, the time before and conditions of storage before and after dilution is the user’s responsibility.<\/p>\n\n\n\n Do not use Midazolam Panpharma if you notice particles in the solution.<\/p>\n\n\n\n Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.<\/p>\n\n\n\n Midazolam Panpharma 1 mg \/ ml solution for injection :<\/p>\n\n\n\n Each ml contains 1 mg of midazolam.<\/p>\n\n\n\n One 5 ml ampoule contains 5 mg midazolam.<\/p>\n\n\n\n Midazolam Panpharma 5 mg \/ ml solution for injection :<\/p>\n\n\n\n Each ml contains 5 mg of midazolam.<\/p>\n\n\n\n One 1 ml ampoule contains 5 mg midazolam.<\/p>\n\n\n\n One 3 ml ampoule contains 15 mg of midazolam.<\/p>\n\n\n\n One 10 ml vial contains 50 mg of midazolam.<\/p>\n\n\n\n Midazolam Panpharma 1 mg \/ ml solution for injection :<\/p>\n\n\n\n The medicine is available as a solution for injection in a 5 ml ampoule<\/p>\n\n\n\n Pack sizes: 5, 6, 10, or 25.<\/p>\n\n\n\n Midazolam Panpharma 5 mg \/ ml solution for injection :<\/p>\n\n\n\n The medicine is available as a solution for injection in:<\/p>\n\n\n\n 1 ml ampoule , pack sizes: 1, 5, 6, 10 or 25<\/p>\n\n\n\n 3 ml ampoule , pack sizes: 1, 5, 6, 10 or 25<\/p>\n\n\n\n 10 ml vial , pack sizes: 1, 5, 6, 10 or 25<\/p>\n\n\n\n Marketing Authorisation Holder:<\/p>\n\n\n\n PANPHARMA<\/p>\n\n\n\n ZI du Claire<\/p>\n\n\n\n 35133 Luitr\u00e9<\/p>\n\n\n\n France<\/p>\n\n\n\n Manufacturer:<\/p>\n\n\n\n PANPHARMA GmbH<\/p>\n\n\n\n Bunsenstrasse 4<\/p>\n\n\n\n 22946 Trittau<\/p>\n\n\n\n Germany<\/p>\n\n\n\n PANPHARMA<\/p>\n\n\n\n ZI du Clairay<\/p>\n\n\n\n 35133 Luitr\u00e9<\/p>\n\n\n\n France<\/p>\n\n\n\n Midazolam Panpharma belongs to a group of medicines called benzodiazepines . It is a short-acting drug used to induce sedation (a state of calm, drowsiness or sleep) and reduces anxiety, muscle tension. It has antispasmodic effects and causes memory loss (anterograde amnesia ).<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,15580],"tags":[17434,17600,8274,17596,17599,8276,8275,17597,8277,17598],"class_list":["post-17952","post","type-post","status-publish","format-standard","hentry","category-medicines","category-m","tag-benefits-of-midazolam","tag-benefits-of-midazolam-panpharma","tag-midazolam","tag-midazolam-panpharma","tag-midazolam-panpharma-side-effects","tag-midazolam-side-effects","tag-what-is-midazolam","tag-what-is-midazolam-panpharma","tag-what-midazolam-is-used-for","tag-what-midazolam-panpharma-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/17952","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=17952"}],"version-history":[{"count":3,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/17952\/revisions"}],"predecessor-version":[{"id":17996,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/17952\/revisions\/17996"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=17952"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=17952"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=17952"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
These symptoms may include:
– headache
– muscle pain
– strong anxiety (anxiety), tension, restlessness, confusion, or bad mood (irritation)
– sleep problems
– mood swings
– hallucinations (see or possibly hear things that do not exist)
– seizures.<\/p>\n\n\n\n
treatment If you are treated with midazolam for a long time, you may become tolerant (midazolam becomes less effective) or you may become addicted to the drug.<\/p>\n\n\n\nOther medicines and Midazolam Panpharma<\/h2>\n\n\n\n
Midazolam Panpharma with food, drink and alcohol<\/h2>\n\n\n\n
Pregnancy, breastfeeding and fertility<\/h2>\n\n\n\n
Driving and using machines<\/h2>\n\n\n\n
Important information about some of the ingredients of Midazolam Panpharma<\/h2>\n\n\n\n
How to use Midazolam Panpharma<\/h2>\n\n\n\n
Your doctor will decide which\u00a0dose\u00a0is right for you.\u00a0The doses\u00a0vary widely and depend on the planned treatment and the\u00a0sedation\u00a0required.\u00a0Your weight, age, general health, how you react to the medicine, and if other medicines are required at the same time also affect the\u00a0dose\u00a0you receive.<\/p>\n\n\n\nIf you use more Midazolam Panpharma than you should <\/h2>\n\n\n\n
If you accidentally overdose, this can lead to drowsiness,\u00a0ataxia\u00a0(inability to coordinate muscle movements),\u00a0dysarthria\u00a0(speech disorder) and\u00a0nystagmus\u00a0(involuntary eye movements), loss of reflexes,\u00a0apnea\u00a0(respiratory arrest),\u00a0hypotension\u00a0(low\u00a0blood pressure\u00a0), decreased heart rate and breathing still\u00a0coming.\u00a0Overdose may require intensive monitoring of vital bodily functions,\u00a0symptomatic\u00a0treatment of cardiac and respiratory effects, and the use of a benzodiazepine antagonist (a drug that counteracts the effect of benzodiazepines).<\/p>\n\n\n\nPossible side effects<\/h2>\n\n\n\n
How to store Midazolam Panpharma<\/h2>\n\n\n\n
Contents of the pack and other information<\/h2>\n\n\n\n
Content declaration<\/h2>\n\n\n\n
What the medicine looks like and contents of the pack<\/h2>\n\n\n\n
Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n
France<\/td> Midazolam Panpharma 1 mg \/ ml
Midazolam Panpharma 5 mg \/ ml<\/td><\/tr>Germany<\/td> Midazolam Panpharma 1 mg \/ ml
Midazolam Panpharma 5 mg \/ ml<\/td><\/tr>Norway<\/td> Midazolam Panpharma 1 mg \/ ml
Midazolam Panpharma 5 mg \/ ml<\/td><\/tr>Sweden<\/td> Midazolam Panpharma 1 mg \/ ml
Midazolam Panpharma 5 mg \/ ml<\/td><\/tr><\/tbody><\/table><\/figure>\n","protected":false},"excerpt":{"rendered":"