{"id":17748,"date":"2022-01-24T07:20:42","date_gmt":"2022-01-24T07:20:42","guid":{"rendered":"https:\/\/zeepedia.com\/?p=17748"},"modified":"2022-01-24T10:57:36","modified_gmt":"2022-01-24T10:57:36","slug":"methotrexate-teva","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/methotrexate-teva\/","title":{"rendered":"Methotr`exate Teva &#8211; Methotrexate uses, dose and side effects"},"content":{"rendered":"\n<p>100 mg \/ ml concentrate for solution for infusion<br>methotrexate<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Methotrexate Teva is and what it is used for<\/h2>\n\n\n\n<p>Methotrexate Teva contains the active substance methotrexate.\u00a0It is a\u00a0cytostatic\u00a0that inhibits cell growth.\u00a0Methotrexate has the greatest effect on cells that multiply frequently, such as cancer cells, bone marrow cells, and skin cells.<\/p>\n\n\n\n<p>Methotrexate Teva is used to treat the following types of cancer:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>acute&nbsp;leukemia&nbsp;(disease affecting the blood or&nbsp;bone marrow&nbsp;one with an increased number of&nbsp;white blood cells&nbsp;)<\/li><li>cancer of the&nbsp;lymphatic system<\/li><li>skeletal cancer (osteogenic&nbsp;sarcoma&nbsp;)<\/li><li>breast cancer<\/li><li>squamous cell carcinoma&nbsp;of the head and neck region<\/li><li>gynecological cancer (trophoblastic&nbsp;tumor&nbsp;er &#8211; tumor development that is directly related to pregnancy)<\/li><li>bladder cancer<\/li><li>small cell lung cancer&nbsp;.<\/li><\/ul>\n\n\n\n<p>Methotrexate contained in Methotrexate Teva may also be approved for the treatment of other conditions not mentioned in this product information.\u00a0Ask your doctor, pharmacist, or another healthcare professional if you have any further questions, and always follow their instructions.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before you receive Methotrexate Teva<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Methotrexate Teva<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to methotrexate or any of the other ingredients of this medicine (listed in section 6)<\/li><li>if you have severe liver or kidney disease<\/li><li>if you consume large amounts of alcohol<\/li><li>if you have any defects in the blood formation<\/li><li>if you have a severe or ongoing&nbsp;infection&nbsp;, e.g.&nbsp;tuberculosis&nbsp;or&nbsp;HIV<\/li><li>if you have sores in your mouth and throat or sores in your stomach and intestines<\/li><li>if you are breast-feeding (see section \u201cPregnancy, breast-feeding and fertility\u201d)<\/li><li>If you, your partner or your healthcare provider discover new or worsening neurological symptoms, such as general muscle weakness, visual disturbances, changes in thinking ability, memory and orientation that lead to confusion and personality changes, you should contact your doctor immediately as this may be a very rare symptom. , severe brain infection called&nbsp;progressive&nbsp;multifocal&nbsp;leukoencephalopathy (PML).<\/li><\/ul>\n\n\n\n<p>While you are being treated with Methotrexate Teva, you should not be vaccinated with a live vaccine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Before starting treatment with Methotrexate Teva Talk to your doctor, pharmacist, or nurse:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are dehydrated or have problems leading to dehydration (vomiting, diarrhea,&nbsp;stomatitis&nbsp;)<\/li><li>if you have an abnormal accumulation of fluid in the abdomen or in the cavity between the lungs and the chest wall (&nbsp;ascites&nbsp;, pleural effusion)<\/li><li>if you have or have had liver disease<\/li><li>if you have impaired kidney function<\/li><li>if you have an&nbsp;infection&nbsp;or if you have an inactive long-term&nbsp;infection&nbsp;(eg&nbsp;tuberculosis&nbsp;,&nbsp;hepatitis&nbsp;B or C,&nbsp;shingles&nbsp;(&nbsp;herpes&nbsp;zoster))<\/li><li>if you have&nbsp;diabetes&nbsp;treated with&nbsp;insulin&nbsp;, then methotrexate&nbsp;treatment&nbsp;should be closely monitored.<\/li><\/ul>\n\n\n\n<p>Talk to your doctor during treatment with Methotrexate Teva:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are to undergo radiation therapy at the same time as methotrexate therapy.&nbsp;The risk of tissue and bone damage may increase with concomitant treatment.<\/li><li>if you are to be vaccinated.&nbsp;Methotrexate may reduce the efficacy of the vaccines.<\/li><\/ul>\n\n\n\n<p>Methotrexate can cause severe and sometimes life-threatening\u00a0side effects.\u00a0Doctors will talk to you about the benefits and risks of treatment and what the early signs and symptoms of\u00a0side effects\u00a0are.<\/p>\n\n\n\n<p>Methotrexate temporarily affects sperm and egg production.&nbsp;Methotrexate can cause miscarriage and severe congenital malformations.&nbsp;You and your partner should avoid having children while you are receiving methotrexate and for at least 6 months after stopping treatment with methotrexate.&nbsp;See also section &#8220;Pregnancy, breast-feeding and fertility&#8221;.<\/p>\n\n\n\n<p>The skin may become extremely sensitive to sunlight and other light during treatment with Methotrexate Teva.&nbsp;Therefore, avoid sunlight and tanning beds.<\/p>\n\n\n\n<p>Methotrexate may cause a decrease in the cells responsible for the immune system, oxygen transport, and the cells responsible for normal blood coagulation and may increase the risk of\u00a0infection\u00a0(ie\u00a0pneumonia\u00a0) or increased bleeding.<\/p>\n\n\n\n<p>Methotrexate may cause\u00a0pneumonia.\u00a0If you have problems with lung function with symptoms such as difficulty breathing, cough (dry cough), and fever, contact a doctor immediately.<\/p>\n\n\n\n<p>Acute\u00a0hemorrhage from the lungs of patients with the underlying rheumatic disease has been reported with methotrexate.<\/p>\n\n\n\n<p>Brain disease (&nbsp;encephalopathy&nbsp;) has been reported as a&nbsp;side effect&nbsp;in patients receiving methotrexate for the treatment of cancer.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Methotrexate Teva<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.\u00a0<\/p>\n\n\n\n<p>It is extra important that you tell your doctor if you use or receive:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>painkillers and anti-&nbsp;inflammatory&nbsp;drugs (so-called&nbsp;NSAIDs&nbsp;and salicylates)<\/li><li>probenecid (for&nbsp;gout&nbsp;)<\/li><li>antibiotics&nbsp;for&nbsp;infection&nbsp;such as&nbsp;penicillins&nbsp;,&nbsp;sulfonamides&nbsp;,&nbsp;tetracycline&nbsp;,&nbsp;ciprofloxacin&nbsp;and chloramphenicol<\/li><li>other anti-cancer drugs such as cisplatin, cytarabine, mercaptopurine<\/li><li>radiation therapy<\/li><li>leflunomide (used in rheumatism)<\/li><li>azathioprine (used to prevent rejection after an organ transplant)<\/li><li>sulfasalazine (used in&nbsp;ulcerative colitis&nbsp;)<\/li><li>retinoids (used for&nbsp;psoriasis&nbsp;or severe acne)<\/li><li>theophylline (used to treat&nbsp;asthma&nbsp;)<\/li><li>phenytoin&nbsp;(for&nbsp;epilepsy&nbsp;)<\/li><li>furosemide&nbsp;(for high&nbsp;blood pressure&nbsp;)<\/li><li>vitamin preparations containing&nbsp;folic acid&nbsp;or substances similar to&nbsp;folic acid<\/li><li>proton pump inhibitor&nbsp;(used to treat heartburn or&nbsp;stomach ulcers&nbsp;).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, breastfeeding and fertility<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor for advice before using this medicine.<\/p>\n\n\n\n<p><em>Pregnancy<\/em><\/p>\n\n\n\n<p>Do not use Methotrexate Teva during pregnancy unless your doctor tells you to<\/p>\n\n\n\n<p>cancer treatment.\u00a0Methotrexate can cause congenital malformations, birth defects, and miscarriages.\u00a0It is associated with malformations of the skull, face, heart and blood vessels, brain arms, and legs.\u00a0It is therefore very important that methotrexate is not given to pregnant women or to women planning to become pregnant unless used for cancer treatment.<\/p>\n\n\n\n<p>For indications other than cancer, a possible pregnancy in fertile women must be ruled out, e.g.&nbsp;through pregnancy tests, before starting treatment.<\/p>\n\n\n\n<p>Do not use Methotrexate Teva if you are trying to conceive.&nbsp;You must avoid becoming pregnant during treatment with methotrexate and for at least 6 months after stopping treatment.&nbsp;Be sure to use effective contraception throughout this time (see also section \u201cWarnings and Precautions\u201d).<\/p>\n\n\n\n<p>If you become pregnant during treatment or suspect you may be pregnant, talk to your doctor as soon as possible.&nbsp;If you become pregnant during treatment, you should be offered medical advice on the risk of harmful effects on the baby due to the treatment.<\/p>\n\n\n\n<p>If you want to get pregnant, talk to your doctor, who can refer you to specialist advice before the planned start of treatment.<\/p>\n\n\n\n<p><em>Breast-feeding<\/em><\/p>\n\n\n\n<p>Methotrexate passes into breast milk in such quantities that there is a risk of the baby being affected.&nbsp;Breast-feeding should therefore be discontinued before treatment with methotrexate.<\/p>\n\n\n\n<p><em>Fertility&nbsp;in men<\/em><\/p>\n\n\n\n<p>Available data do not indicate an increased risk of malformations or miscarriages if the father takes less methotrexate than 30 mg\/week.\u00a0However, risk can not be completely ruled out and there is no information on higher\u00a0doses\u00a0of methotrexate.\u00a0Methotrexate may have genotoxic effects.\u00a0This means that the drug can cause gene mutations.\u00a0Methotrexate can affect sperm production, which is associated with the risk of congenital malformations.<\/p>\n\n\n\n<p>You should avoid getting a woman pregnant and donating sperm during treatment with methotrexate and for at least 6 months after stopping treatment.\u00a0Because treatment with methotrexate may cause\u00a0infertility\u00a0and gene mutations at higher\u00a0doses\u00a0that are common in cancer treatment, male patients treated with methotrexate at\u00a0doses\u00a0above 30 mg\/week should consider sperm preservation before starting treatment (see also section \u201cWarnings and precautions\u201d).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Methotrexate can cause&nbsp;side effects&nbsp;such as vomiting and dizziness.&nbsp;If you feel tired or dizzy, do not drive or use machines.<\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects.\u00a0Descriptions of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Methotrexate Teva contains sodium<\/h2>\n\n\n\n<p>This medicine contains 101 mg\u00a0sodium\u00a0(the main ingredient in table salt\/table salt) per 10 ml\u00a0vial\u00a0and 506 mg\u00a0sodium\u00a0per 50 ml\u00a0vial.\u00a0This corresponds to 5% and 25% respectively of the highest recommended daily intake of\u00a0sodium\u00a0for adults.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to get Methotrexate Teva<\/h2>\n\n\n\n<p>Methotrexate Teva is given to you by healthcare professionals.<\/p>\n\n\n\n<p>The\u00a0dose\u00a0you receive and how often you receive it depends on the disease you are being treated for, your state of health, and your age, weight, and body surface area.\u00a0Methotrexate Teva can be given in a vein (\u00a0intravenously\u00a0) or an\u00a0artery\u00a0(intraarterially).<\/p>\n\n\n\n<p>Before starting treatment, your doctor may take blood samples and also check how well your kidneys and liver are working.&nbsp;You may also have a lung x-ray.&nbsp;Additional tests can also be done during and after treatment.&nbsp;Do not miss appointments for blood tests.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you take more Methotrexate Teva than you should<\/h2>\n\n\n\n<p>In case of overdose, you may experience increased\u00a0side effects.\u00a0See also section 4.<\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.\u00a0Methotrexate Teva can have\u00a0side effects\u00a0that can be dangerous or life-threatening.\u00a0During treatment, you should be alert for signs of\u00a0side effects\u00a0and tell your doctor about them.<\/p>\n\n\n\n<p><strong>Contact a doctor immediately if you experience any of the following\u00a0side effects.\u00a0You may need\u00a0urgent\u00a0medical attention.<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Unexplained shortness of breath, dry cough and fever (symptoms of lung disease).<\/li><li>Sudden&nbsp;itching&nbsp;, rash (&nbsp;hives&nbsp;), swelling of the hands, feet, ankles, face, lips, mouth or throat (which may make it difficult to breathe and swallow).&nbsp;It may also feel like you will faint (symptoms of an&nbsp;allergic reaction&nbsp;).<\/li><li>Yellowing of the skin or eyes, dark-colored urine (symptoms of hepatic impairment).<\/li><li>Unexpected bleeding (eg bleeding gums, dark urine, blood in urine or vomiting) or unexpected bruising, black, tarry stools.&nbsp;This may be due to decreased coagulation ability or bleeding from the stomach or intestines due to low levels of&nbsp;platelets&nbsp;.<\/li><li>An extremely severe&nbsp;allergic reaction&nbsp;with skin rash usually in the form of blisters or sores in the oral cavity and eyes as well as other mucous membranes such as genitals.<\/li><li>Severe skin damage (skin detachment of the epidermis and superficial mucous membranes).<\/li><li>Half-sided muscle weakness, seizures, dizziness.&nbsp;This may be a symptom ofbrain disease (&nbsp;encephalopathy&nbsp;) which can be life threatening.<\/li><\/ul>\n\n\n\n<p><strong>Other&nbsp;side effects&nbsp;may occur<\/strong><\/p>\n\n\n\n<p><em>Very common (may affect more than 1 user in 10):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Blood effects (eg low&nbsp;white blood cell levels&nbsp;)<\/li><li>Loss of appetite, nausea, vomiting and abdominal pain<\/li><li>Inflammation&nbsp;and ulceration and pain in the mouth and throat<\/li><li>Elevated liver enzymes<\/li><\/ul>\n\n\n\n<p><em>Common (may affect up to 1 in 10&nbsp;<\/em><em>people):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Shingles&nbsp;(&nbsp;infection&nbsp;with&nbsp;Herpes&nbsp;zoster&nbsp;virus&nbsp;)<\/li><li>Pneumonia<\/li><li>Impact on&nbsp;bone&nbsp;marrow<\/li><li>Anemia<\/li><li>Deficiency of all types of&nbsp;blood cells&nbsp;in the blood (pancytopenia)<\/li><li>Headache<\/li><li>Diarrhea<\/li><li>Liver damage during high-dose treatment for a long time<\/li><li>Skin rash in the form of redness,&nbsp;itching&nbsp;and&nbsp;hives&nbsp;,<\/li><li>Renal&nbsp;impairment especially after treatment with high&nbsp;doses<\/li><li>Feeling sick, tired<\/li><\/ul>\n\n\n\n<p><em>Uncommon (may affect up to 1 in 100 people):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Cystitis&nbsp;, vaginitis, increased susceptibility to infection<\/li><li>Infection&nbsp;is seen in patients with weakened immune systems<\/li><li>Immunocompromised<\/li><li>Acceleration of&nbsp;diabetes<\/li><li>Eye inflammation<\/li><li>Lymphoma&nbsp;(&nbsp;tumor&nbsp;of the lymph nodes)<\/li><li>Inflammation&nbsp;of the blood vessels in the hands and feet<\/li><li>Lung disease (&nbsp;lung fibrosis&nbsp;).<\/li><li>Bleeding or ulcers in the abdomen and intestines,&nbsp;inflammation&nbsp;of the intestines.<\/li><li>Cirrhosis of the liver,&nbsp;fatty liver&nbsp;.<\/li><li>Hair loss<\/li><li>Osteoporosis&nbsp;, joint pain (&nbsp;arthralgia&nbsp;)&nbsp;, muscle aches (&nbsp;myalgia&nbsp;).<\/li><li>Renal impairment, kidney damage, pain and difficulty emptying the bladder<\/li><li>Fertility disorders in the form of&nbsp;defects&nbsp;when eggs and sperm are formed, low sperm count, menstrual disorders,&nbsp;infertility&nbsp;.<\/li><li>Inflammation&nbsp;and ulceration of the vagina.<\/li><li>Congenital malformations<\/li><li>Decreased&nbsp;serum&nbsp;albumin levels seen in blood tests<\/li><li>Fever<\/li><\/ul>\n\n\n\n<p><em>Rare (may affect up to 1 in 1,000 people&nbsp;<\/em><em>)<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Blood poisoning, pharyngitis<\/li><li>Anemia&nbsp;due to&nbsp;abnormal development of the red&nbsp;blood&nbsp;cells<\/li><li>Mood swings<\/li><li>Temporarily impaired&nbsp;cognitive&nbsp;function such as memory, learning and problem solving,<\/li><li>Paralysis<\/li><li>Impact on speech including&nbsp;dysarthria&nbsp;(difficulty speaking due to reduced muscle mobility) and&nbsp;aphasia&nbsp;(inability or impaired ability to use and \/ or understand language)<\/li><li>Brain disease with high-dose treatment<\/li><li>Epileptic seizures<\/li><li>Eye irritation, blurred vision, blurred vision.<\/li><li>Blood clots<\/li><li>Gingivitis<\/li><li>Black, tarry, foul-smelling feces containing decomposed blood.<\/li><li>Liver damage<\/li><li>Nodules, bruises,&nbsp;acne&nbsp;, skin rashes, skin ulcers,&nbsp;psoriasis&nbsp;flare-ups ,<\/li><li>Elevated levels of nitrogen in the blood (azotemia), blood in the urine<\/li><li>Abortion<\/li><li>Stress fracture<\/li><\/ul>\n\n\n\n<p><em>Very rare (may affect up to 1 in 10,000 people&nbsp;<\/em><em>):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Bacterial infection, usually in the lungs, with&nbsp;<em>Nokardia<\/em>&nbsp;bacteria.<\/li><li>Fungal infection, usually in the lungs<\/li><li>Herpes&nbsp;virus infection in the liver or with widespread blisters on the skin<\/li><li>Widespread skin infection with abscesses<\/li><li>Inflammation of the pericardium, accumulation of fluid in the pericardium<\/li><li>Severe decrease in&nbsp;blood cells&nbsp;which may cause weakness, bruising or increase the risk of&nbsp;infection&nbsp;(&nbsp;aplastic anemia&nbsp;), low levels of&nbsp;neutrophils&nbsp;(a type of&nbsp;white blood cell&nbsp;), swollen&nbsp;lymph nodes&nbsp;(&nbsp;lymphadenopathy&nbsp;)<\/li><li>Low&nbsp;levels of&nbsp;antibodies<\/li><li>Decreased sex drive<\/li><li>Disorder of sensory impressions such as sight, hearing, smell and touch.<\/li><li>Transient blindness, loss of vision<\/li><li>Rapid decay of tumor cells (tumor lysis syndrome)<\/li><li>Lymphoproliferative disorders (abnormal growth of&nbsp;white blood cells&nbsp;)<\/li><li>Prolonged lung disease with dry cough, shortness of breath and fever (&nbsp;chronic&nbsp;interstitial lung disease)<\/li><li>Bloody vomiting<\/li><li>Reduction of liver size (liver atrophy), decay and death of liver cells (liver necrosis)<\/li><li>Enlargement of the superficial blood vessels of the skin (telangiectasias)<\/li><li>Impotence<\/li><li>Sudden death<\/li><\/ul>\n\n\n\n<p><em>Has been reported: occurs in an unknown number of users:<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Bone damage in the jaw (as a result of abnormal growth of&nbsp;white blood cells&nbsp;).<\/li><li>Reddening and flaky skin<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Methotrexate Teva<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Store in the outer carton.&nbsp;Sensitive to light.<\/p>\n\n\n\n<p>Used before the expiration date specified after Expiration Date \/ EXP.\u00a0The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the pack and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is methotrexate.&nbsp;1 ml of concentrate contains 100 mg of methotrexate.<\/li><li>The other ingredients are sodium hydroxide,&nbsp;hydrochloric acid&nbsp;and water for injections.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and contents of the pack<\/h2>\n\n\n\n<p>Stained&nbsp;glass vial.<\/p>\n\n\n\n<p>Pack sizes:<\/p>\n\n\n\n<p>1 x 10 ml, 10 x 10 ml and 1 x 50 ml<\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Methotrexate Teva contains the active substance methotrexate. It is a cytostatic that inhibits cell growth. Methotrexate has the greatest effect on cells that multiply frequently, such as cancer cells, bone marrow cells and skin cells.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,15580],"tags":[12794,17248,17243,4860,17244,17247,4859,17245,12793,17246],"class_list":["post-17748","post","type-post","status-publish","format-standard","hentry","category-medicines","category-m","tag-benefits-of-methotrexate","tag-benefits-of-methotrexate-teva","tag-methotrexate-dosage","tag-methotrexate-side-effects","tag-methotrexate-teva","tag-methotrexate-teva-side-effects","tag-what-is-methotrexate","tag-what-is-methotrexate-teva","tag-what-methotrexate-is-used-for","tag-what-methotrexate-teva-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/17748","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=17748"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/17748\/revisions"}],"predecessor-version":[{"id":17780,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/17748\/revisions\/17780"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=17748"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=17748"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=17748"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}