500 mg, 850 mg and 1000 mg film-coated tablets
Metformin hydrochloride<\/p>\n\n\n\n
Metformin\u00a0Orifarm contains the active substance metformin hydrochloride.\u00a0Metformin hydrochloride belongs to a group of medicines called biguanides and is used in patients with non-insulin-dependent (type II)\u00a0diabetes\u00a0in adults and children from 10 years of age.<\/p>\n\n\n\n
Insulin is a hormone produced in the pancreas that helps the body absorb glucose (sugar) from the blood. The body uses glucose to produce energy or stores it for future needs.<\/p>\n\n\n\n
If you have\u00a0diabetes, the pancreas does not produce enough\u00a0insulin\u00a0or the body cannot use the\u00a0insulin\u00a0that is produced well enough.\u00a0This leads to high glucose levels in the blood.\u00a0Metformin\u00a0helps to lower blood glucose levels to a level that is as close to normal as possible.
If you are an adult and overweight, taking\u00a0metformin\u00a0for a long time can also help reduce the risk of complications associated with\u00a0diabetes.\u00a0Metformin\u00a0is associated with either stable body weight or a slight weight loss.<\/p>\n\n\n\n
Metformin Orifarm is a medicine used to treat type 2 diabetes mellitus in adults, especially in obese people, where diet and exercise alone do not provide sufficient control over blood sugar.<\/p>\n\n\n\n
Adults<\/strong> <\/p>\n\n\n\n Your doctor may prescribe Metformin Orifarm as the only treatment or in combination with other medicines to treat diabetes (medicines taken by mouth or insulin ).<\/p>\n\n\n\n Children and young people<\/strong> <\/p>\n\n\n\n Children 10 years of age or older and adolescents can take\u00a0Metformin\u00a0Orifarm as their only treatment or with\u00a0insulin.<\/p>\n\n\n\n Metformin hydrochloride contained in\u00a0Metformin\u00a0Orifarm may also be approved for the treatment of other conditions not mentioned in this product information.\u00a0Ask your doctor, pharmacist or another healthcare professional if you have any further questions and always follow their instructions.<\/p>\n\n\n\n You need to consult a doctor about<\/p>\n\n\n\n You must stop taking\u00a0metformin\u00a0for a certain period before and after the examination or operation.\u00a0Your doctor will decide if you need any other treatment during this time.\u00a0You must follow your doctor’s instructions carefully.<\/p>\n\n\n\n Talk to your doctor, pharmacist or nurse before taking Metformin Orifarm.<\/p>\n\n\n\n Risk of lactic acidosis<\/strong><\/p>\n\n\n\n Metformin\u00a0Orifarm can cause the very rare, but very serious\u00a0side effect\u00a0of\u00a0lactic acidosis, particularly if your kidneys are not working properly.\u00a0The risk of developing\u00a0lactic acidosis\u00a0is also increased in uncontrolled\u00a0diabetes, severe\u00a0infections, prolonged fasting or alcohol intake, dehydration (see more information below), liver problems and conditions where part of the body has reduced oxygen supply (including\u00a0acute\u00a0severe heart disease).<\/p>\n\n\n\n If any of the above apply to you, talk to your doctor for further information.<\/p>\n\n\n\n Stop taking\u00a0Metformin\u00a0Orifarm for a short time if you have a condition that may be associated with dehydration<\/strong>, such as severe vomiting, diarrhoea, fever, exposure to heat or if you drink less fluid than normal.\u00a0Talk to a doctor for further instructions.<\/p>\n\n\n\n Stop taking\u00a0Metformin\u00a0Orifarm and contact your doctor or nearest hospital immediately if you experience any of the symptoms of\u00a0lactic acidosis<\/strong>\u00a0as the condition may lead to\u00a0coma.<\/p>\n\n\n\n The symptoms of lactic acidosis include:<\/p>\n\n\n\n Lactic acidosis is an acute medical condition that must be treated in a hospital.<\/p>\n\n\n\n If you are going to have a major operation, you must stop taking\u00a0Metformin\u00a0Orifarm during the operation and for some time after it.\u00a0Your doctor will decide when you need to stop taking\u00a0Metformin\u00a0Orifarm and when you should start taking it again. During treatment with\u00a0Metformin\u00a0Orifarm, your doctor will check your kidney function at least once a year or more often if you are older and\/or if your kidney function is deteriorating.<\/p>\n\n\n\n Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.<\/p>\n\n\n\n If you need to get an\u00a0injection\u00a0in the blood with contrast media that contain iodine, for example in connection with an X-ray or\u00a0computed tomography, you must stop taking\u00a0Metformin\u00a0Orifarm before or at the time of\u00a0injection.\u00a0Your doctor will decide when you need to stop taking\u00a0Metformin\u00a0Orifarm and when you should start taking it again.<\/p>\n\n\n\n You may need to have more blood sugar and kidney function tests, or your doctor may need to adjust the\u00a0dose\u00a0of\u00a0Metformin\u00a0Orifarm.\u00a0You must mention the following:<\/p>\n\n\n\nWhat you need to know before you use Metformin Orifarm<\/h2>\n\n\n\n
Do not take Metformin Orifarm<\/h2>\n\n\n\n
Warnings and cautions<\/h2>\n\n\n\n
Metformin\u00a0itself does not cause\u00a0hypoglycemia\u00a0(too low blood sugar), but if you take\u00a0metformin\u00a0with other antidiabetic medicines\u00a0that\u00a0can cause\u00a0hypoglycaemia\u00a0(eg sulphonylureas,\u00a0insulin, meglitinides) there is a risk of\u00a0hypoglycaemia.\u00a0If you get symptoms of\u00a0hypoglycemia, such as weakness, dizziness, increased sweating, rapid\u00a0heartbeat, visual disturbances, or difficulty concentrating, it usually helps to eat or drink something that contains sugar.<\/p>\n\n\n\nOther medicines and Metformin Orifarm<\/h2>\n\n\n\n