{"id":17609,"date":"2022-01-19T11:45:08","date_gmt":"2022-01-19T11:45:08","guid":{"rendered":"https:\/\/zeepedia.com\/?p=17609"},"modified":"2022-01-20T10:55:29","modified_gmt":"2022-01-20T10:55:29","slug":"meronem","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/meronem\/","title":{"rendered":"Meronem &#8211; Meropenem uses, dose and side effects"},"content":{"rendered":"\n<p>500 mg and 1 g powder for solution for injection or infusion<br>meropenem<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Meronem is and what it is used for<\/h2>\n\n\n\n<p>Meronem belongs to a group of medicines called carbapenem\u00a0antibiotics.\u00a0It works by killing bacteria that can cause serious\u00a0infections.<\/p>\n\n\n\n<p>Meronem is used to treat the following in adults and children aged 3 months and older:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Lung infection&nbsp;(&nbsp;pneumonia&nbsp;)<\/li><li>Infection&nbsp;in the lungs and&nbsp;bronchus&nbsp;in patients with&nbsp;cystic fibrosis<\/li><li>Complicated urinary tract infections<\/li><li>Complicated abdominal infections<\/li><li>Infection&nbsp;you that can occur during or after childbirth<\/li><li>Complicated&nbsp;infection&nbsp;is in the skin or soft tissues<\/li><li>Acute bacterial infections in the brain (&nbsp;meningitis&nbsp;)<\/li><\/ul>\n\n\n\n<p>Meronem can be used to treat&nbsp;neutropenic&nbsp;patients with fever that is suspected to be caused by a bacterial infection.<\/p>\n\n\n\n<p>Meronem can be used to treat bacterial infections in the blood that may be associated with any of the&nbsp;infections&nbsp;mentioned above.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before you use Meronem<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Meronem again<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>you are allergic (hypersensitive) to meropenem or any of the other ingredients of this medicine (listed in section 6).<\/li><li>you are allergic (hypersensitive) to other&nbsp;antibiotics&nbsp;, such as&nbsp;penicillins&nbsp;,&nbsp;cephalosporins&nbsp;or carbapenems, as you may also be allergic to meropenem.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor, pharmacist, or nurse before receiving Meronem if:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>you have health problems, such as liver or kidney disease.<\/li><li>you have severe diarrhea after taking other&nbsp;antibiotics&nbsp;.<\/li><\/ul>\n\n\n\n<p>You can get a positive result on a blood test (Coombs test) which indicates the presence of\u00a0antibodies\u00a0that can destroy your\u00a0red blood cells.\u00a0Your doctor will talk to you about this.<\/p>\n\n\n\n<p>You may experience signs and symptoms of severe skin reactions (see section 4).&nbsp;If this happens, talk to a doctor or nurse immediately so you can get treatment for your symptoms.<\/p>\n\n\n\n<p>If you are not sure if any of the above applies to you, talk to your doctor or nurse before receiving Meronem.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Meronem<\/h2>\n\n\n\n<p>Tell your doctor, pharmacist, or nurse if you are taking, have recently taken, or might take any other medicines.<\/p>\n\n\n\n<p>This is because some medicines may affect or be affected by treatment with Meronem.<\/p>\n\n\n\n<p>In particular, tell your doctor, pharmacist, or nurse if you are taking the following medicines:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Probenecid (medicine for&nbsp;gout&nbsp;).<\/li><li>Valproic acid \/ sodium valproate \/ valpromide (antiepileptic medicine&nbsp;)&nbsp;.&nbsp;Meronem should not be used as it may impair the effect of sodium valproate.<\/li><li>Blood thinners taken by mouth (used to treat or prevent blood clots).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.\u00a0It is desirable to avoid Meronem during pregnancy.\u00a0Your doctor will decide if you should receive Meronem.<\/p>\n\n\n\n<p>You must tell your doctor if you are breastfeeding or planning to start breastfeeding before receiving Meronem.\u00a0Small amounts of this medicine may pass into breast milk.\u00a0Therefore, your doctor will decide if you should be given Meronem while you are breastfeeding.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>No studies on the effects on the ability to drive and use machines have been performed.<\/p>\n\n\n\n<p>Meronem has been associated with headaches and tingling and tingling in the skin (&nbsp;paresthesia&nbsp;).&nbsp;All of these&nbsp;side effects&nbsp;can affect your ability to drive and use machines.<\/p>\n\n\n\n<p>Meronem can cause involuntary muscle movements, which can cause a person&#8217;s body to shake quickly and uncontrollably (cramps).\u00a0This is usually accompanied by loss of consciousness.\u00a0You should not drive or use machines if you experience this\u00a0side effect.<\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects.\u00a0Descriptions of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Meronem contains sodium<\/h2>\n\n\n\n<p>Meronem 500 mg: This medicine contains 45 mg of\u00a0sodium\u00a0(the main ingredient in common table salt\/table salt) per 500 mg\u00a0dose.\u00a0This corresponds to 2.25% of the maximum recommended daily\u00a0sodium\u00a0intake for adults.<\/p>\n\n\n\n<p>Meronem 1 g: This medicine contains 90 mg\u00a0sodium\u00a0(the main ingredient in common table salt\/table salt) per 1 g\u00a0dose.\u00a0This corresponds to 4.5% of the maximum recommended daily\u00a0sodium\u00a0intake for adults.<\/p>\n\n\n\n<p>If you have a health problem that requires you to control your\u00a0sodium\u00a0intake, tell your doctor, pharmacist, or nurse.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to use Meronem<\/h2>\n\n\n\n<p>Always use this medicine exactly as your doctor, pharmacist or nurse has told you.\u00a0If you are not sure, talk to your doctor, pharmacist, or nurse.<\/p>\n\n\n\n<p><strong>Use for adults<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Dose&nbsp;one depends on the type of&nbsp;infection&nbsp;you have, where in the body&nbsp;infection&nbsp;one is sitting and how serious it is.&nbsp;Your doctor will determine the&nbsp;dose&nbsp;you need<\/li><li>One dose&nbsp;for adults is usually between 500 mg (milligrams) and 2 g (grams).&nbsp;You are usually given one&nbsp;dose&nbsp;every 8 hours.&nbsp;But you get a&nbsp;dose&nbsp;less often if your kidneys do not work really well.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Use for children and adolescents<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Dose&nbsp;one for children over 3 months and up to 12 years depends on the child&#8217;s age and weight.&nbsp;The usual&nbsp;dose&nbsp;is between 10 mg and 40 mg of Meronem for each kilogram (kg) that the child weighs.&nbsp;One&nbsp;dose&nbsp;is usually given every 8 hours.&nbsp;Children weighing over 50 kg will receive an adult dose.<\/li><\/ul>\n\n\n\n<p><strong>How to use Meronem<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Meronem will be given to you as an&nbsp;injection&nbsp;or&nbsp;infusion&nbsp;into a large vein<\/li><li>Your doctor or nurse will normally give you Meronem<\/li><li>Some patients, parents or caregivers are sometimes trained to give Meronem at home.&nbsp;Instructions for doing this can be found in this leaflet (in the section: Instructions for giving Meronem to yourself or someone else in the home).&nbsp;Always use Meronem exactly as your doctor has told you.&nbsp;If you are not sure, talk to your doctor.<\/li><li>Your&nbsp;injection&nbsp;should not be mixed with or added to solutions containing other medicines<\/li><li>Injection&nbsp;one can take about 5 minutes or between 15 and 30 minutes.&nbsp;Your doctor will tell you how to give Meronem<\/li><li>You should normally get your&nbsp;injections&nbsp;at the same time each day<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">If you use more Meronem than you should&nbsp;<\/h2>\n\n\n\n<p>If you accidentally use more than your prescribed\u00a0dose, contact your doctor or nearest hospital immediately.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to use Meronem<\/h2>\n\n\n\n<p>If you miss an\u00a0injection, you should get it as soon as possible.\u00a0But if it&#8217;s almost time for the next\u00a0injection, skip the missed\u00a0injection.<\/p>\n\n\n\n<p>You should not be given a double\u00a0dose\u00a0(two\u00a0injections\u00a0at the same time) to compensate for a missed\u00a0dose.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop using Meronem<\/h2>\n\n\n\n<p>Do not stop using Meronem until your doctor tells you to.<\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor, pharmacist, or nurse.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p><strong>Severe allergic reactions<\/strong><\/p>\n\n\n\n<p>If you get any of these signs or symptoms,\u00a0talk to a doctor\u00a0or nurse\u00a0immediately.\u00a0You may need urgent medical attention.\u00a0The symptoms and signs may appear suddenly:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Severe rash,&nbsp;itching&nbsp;or&nbsp;hives&nbsp;on the skin<\/li><li>Swelling of the face, lips, tongue or other parts of the body<\/li><li>Shortness of breath, wheezing or difficulty breathing<\/li><li>Signs and symptoms of severe skin reactions, including:<ul><li>Severe&nbsp;hypersensitivity reaction&nbsp;with fever, rash and changes in blood tests to check liver function (elevated levels of liver enzymes) and an increase in a type of&nbsp;white blood cell&nbsp;(&nbsp;eosinophilia&nbsp;) and enlarged&nbsp;lymph nodes&nbsp;.&nbsp;These can be signs of a&nbsp;hypersensitivity reaction&nbsp;in several organs called DRESS syndrome.<\/li><li>Severe red and scaly rashes, bulging bumps, blisters or flaky skin that may be associated with high fever and joint pain.<\/li><li>Severe skin rashes that may appear as reddish round spots, often with blisters in the middle of the torso, flaky skin, sores in the mouth, throat, nose, genitals and eyes, and which may be preceded by fever and&nbsp;flu-like symptoms&nbsp;(&nbsp;Stevens-Johnson syndrome&nbsp;) or a more severe form (&nbsp;toxic epidermal necrolysis&nbsp;).<\/li><\/ul><\/li><\/ul>\n\n\n\n<p><strong>Damage to&nbsp;red blood cells&nbsp;(no known frequency)<\/strong><\/p>\n\n\n\n<p>Symptoms that may occur:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Shortness of breath when you do not expect it<\/li><li>Red or brown urine<\/li><\/ul>\n\n\n\n<p>If you notice any of the above symptoms,&nbsp;<strong>contact a doctor immediately.<\/strong><\/p>\n\n\n\n<p><strong>Other possible side effects:<\/strong><\/p>\n\n\n\n<p><strong>Common (may affect up to 1 in 10 people)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Magont<\/li><li>Nausea<\/li><li>Vomiting<\/li><li>Diarrhea<\/li><li>Headache<\/li><li>Skin rash,&nbsp;itching<\/li><li>Pain and&nbsp;inflammation<\/li><li>Increased&nbsp;platelet count&nbsp;in the blood (measured in a blood test)<\/li><li>Changes in blood tests, including tests that show how well your liver is working<\/li><\/ul>\n\n\n\n<p><strong>Uncommon (may affect up to 1 in 100 people)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Changes in the blood.&nbsp;These include decreased&nbsp;platelet count&nbsp;(which makes it easier for you to get bruises), increased number of certain&nbsp;white blood cells&nbsp;, decreased number of other&nbsp;white blood cells&nbsp;and increased amounts of a substance called &#8216;bilirubin&#8217;.&nbsp;Your doctor may take blood samples from time to time<\/li><li>Changes in values \u200b\u200bfrom blood tests, including tests that show how well your kidneys are working<\/li><li>Tingling and tingling<\/li><li>Fungal infections of the mouth or abdomen<\/li><li>Inflammation&nbsp;of the intestine with diarrhea<\/li><li>Tenderness in the vein where Meronem is injected<\/li><li>Other changes in the blood.&nbsp;Symptoms may include frequent&nbsp;infections&nbsp;, high fever and sore throat.&nbsp;Your doctor may take blood samples from time to time<\/li><\/ul>\n\n\n\n<p><strong>Rare&nbsp;<\/strong><strong>(&nbsp;<\/strong><strong>may&nbsp;<\/strong><strong>affect&nbsp;<\/strong><strong>up&nbsp;<\/strong><strong>to 1 in 1000&nbsp;<\/strong><strong>people&nbsp;<\/strong><strong>)<\/strong><strong><\/strong><strong><\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Cramps<\/li><li>Rapidly disorientation and confusion (&nbsp;delirium&nbsp;)<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Meronem<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the carton.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>Do not store above 30 \u00b0 C.<\/p>\n\n\n\n<p><strong>Injection<\/strong><\/p>\n\n\n\n<p>Reconstituted solution: The reconstituted solution for&nbsp;intravenous&nbsp;injection&nbsp;should be used immediately.&nbsp;The time between the start of dilution and the end of&nbsp;intravenous&nbsp;injection&nbsp;should not exceed:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>3 hours when stored at up to 25 \u00b0 C).<\/li><li>12 hours in cold storage (2-8 \u00b0 C).<\/li><\/ul>\n\n\n\n<p><strong>Infusion<\/strong><\/p>\n\n\n\n<p>After reconstitution: Prepared&nbsp;intravenous&nbsp;infusion solutions&nbsp;should be used immediately.&nbsp;The time between the start of&nbsp;reconstitution&nbsp;and the end of&nbsp;intravenous&nbsp;infusion&nbsp;should not exceed:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>3 hours when stored at up to 25 \u00b0 C) if Meronem has been dissolved in sodium chloride;<\/li><li>24 hours in cold storage (2-8 \u00b0 C) if Meronem has been dissolved in sodium chloride.<\/li><li>If Meronem has been dissolved in&nbsp;glucose&nbsp;(dextrose), the solution should be used immediately.<\/li><\/ul>\n\n\n\n<p>From a\u00a0microbiological\u00a0point of view, the product should be used immediately, unless the method of opening\/preparation\/dilution excludes the risk of\u00a0microbial\u00a0contamination.<\/p>\n\n\n\n<p>If the product is not used immediately, the storage times and conditions of use are the user&#8217;s responsibility.<\/p>\n\n\n\n<p>The prepared solution must not be frozen.<\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the pack and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<p>Meronem 500 mg: The active substance is meropenem.&nbsp;1 vial contains meropenem trihydrate equivalent to 500 mg anhydrous meropenem.<\/p>\n\n\n\n<p>Meronem 1 g: The active substance is meropenem.&nbsp;1 vial contains meropenem trihydrate equivalent to 1 g anhydrous meropenem.<\/p>\n\n\n\n<p>The other ingredient is anhydrous sodium carbonate.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and contents of the pack<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Meronem is a white or light yellow powder for solution for&nbsp;injection&nbsp;or&nbsp;infusion&nbsp;in&nbsp;a vial&nbsp;.&nbsp;There are 1 or 10 vials per pack.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p><em>Marketing Authorisation Holder<\/em><\/p>\n\n\n\n<p>Pfizer AB<\/p>\n\n\n\n<p>191 90 Sollentuna<\/p>\n\n\n\n<p>Tel: 08 &#8211; 550 520 00<\/p>\n\n\n\n<p>Email: eumedinfo@pfizer.com<\/p>\n\n\n\n<p><em>Manufacturer<\/em><\/p>\n\n\n\n<p>Pfizer Service Company BVBA<\/p>\n\n\n\n<p>10 High Way<\/p>\n\n\n\n<p>1930 Zaventem<\/p>\n\n\n\n<p>Belgium<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Meronem belongs to a group of medicines called carbapenem antibiotics . It works by killing bacteria that can cause serious infection .<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,15580],"tags":[17140,17117,17136,17139,17112,17116,17137,17113,17138,17114],"class_list":["post-17609","post","type-post","status-publish","format-standard","hentry","category-medicines","category-m","tag-benefits-of-meronem","tag-benefits-of-meropenem","tag-meronem","tag-meronem-side-effects","tag-meropenem","tag-meropenem-side-effects","tag-what-is-meronem","tag-what-is-meropenem","tag-what-meronem-is-used-for","tag-what-meropenem-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/17609","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=17609"}],"version-history":[{"count":5,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/17609\/revisions"}],"predecessor-version":[{"id":17681,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/17609\/revisions\/17681"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=17609"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=17609"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=17609"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}