{"id":17560,"date":"2022-01-17T10:30:16","date_gmt":"2022-01-17T10:30:16","guid":{"rendered":"https:\/\/zeepedia.com\/?p=17560"},"modified":"2022-01-17T12:16:53","modified_gmt":"2022-01-17T12:16:53","slug":"memantine-ratiopharm","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/memantine-ratiopharm\/","title":{"rendered":"Memantine ratiopharm &#8211; Memantine hydrochloride uses, dose and side effects"},"content":{"rendered":"\n<p>5 mg, 10 mg, 15 mg, 20 mg&nbsp;film-coated tablets<br>memantine hydrochloride<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Memantine ratiopharm is and what it is used for<\/h2>\n\n\n\n<p><strong>How Memantine Ratiopharm<\/strong> works<br>Memantine Ratiopharm contains the active substance memantine hydrochloride.\u00a0It belongs to a group of medicines known as anti-dementia medicines.<\/p>\n\n\n\n<p>Memory loss in\u00a0Alzheimer&#8217;s disease\u00a0is due to a disturbance of message signals in the brain.\u00a0The brain contains so-called NMDA\u00a0receptors\u00a0(N-methyl-D-aspartate) that are involved in the transmission of nerve signals that are important for learning and memory.\u00a0Memantine Ratiopharm belongs to a group of medicines called NMDA receptor antagonists.\u00a0Memantine Ratiopharm acts on these NMDA\u00a0receptors\u00a0by improving the transmission of nerve signals and memory.<\/p>\n\n\n\n<p><strong>What Memantine Ratiopharm<\/strong> is used for<br>Memantine Ratiopharm is used for treating patients with moderate to severe\u00a0Alzheimer&#8217;s disease.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before you take Memantine ratiopharm<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Memantine ratiopharm<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to memantine hydrochloride, peanuts or soy or any of the other ingredients of this medicine (listed in section 6).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before taking Memantine Ratiopharm:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you have a history of epileptic seizures.<\/li><li>if you have recently had a&nbsp;myocardial infarction&nbsp;(heart attack) or if you suffer from untreated&nbsp;heart failure&nbsp;or uncontrolled&nbsp;hypertension&nbsp;(high&nbsp;blood pressure&nbsp;).<\/li><\/ul>\n\n\n\n<p>In these situations, treatment should be closely monitored and the clinical benefit of Memantine Ratiopharm should be regularly assessed by your physician.<\/p>\n\n\n\n<p>If you suffer from impaired kidney function (kidney problems), your doctor should closely monitor your kidney function and, if necessary, adjust the memantine doses accordingly.<\/p>\n\n\n\n<p>Concomitant use of drugs containing<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>amantadine (for the treatment of&nbsp;Parkinson&#8217;s disease&nbsp;)<\/li><li>ketamine (a substance commonly used as an anesthetic)<\/li><li>dextromethorphan (generally used to treat cough)<\/li><li>other NMDA&nbsp;antagonist&nbsp;er<\/li><\/ul>\n\n\n\n<p>should be avoided.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children and young people<\/h2>\n\n\n\n<p>Memantine Ratiopharm is not recommended for children and adolescents under 18 years of age.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Memantine ratiopharm<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking\/using, have recently taken\/used, or might take\/use any other medicines.<\/p>\n\n\n\n<p>Memantine Ratiopharm may in particular affect the effects of the following medicines and these\u00a0doses\u00a0may need to be changed by your doctor:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>amantadine, ketamine, dextromethorphan<\/li><li>dantrolen, baklofen<\/li><li>cimetidine, ranitidine,&nbsp;procainamide&nbsp;,&nbsp;quinidine&nbsp;, quinine, nicotine<\/li><li>hydrochlorothiazide (or any combination with hydrochlorothiazide)<\/li><li>anticholinergics (substances commonly used to treat movement disorders or intestinal cramps)<\/li><li>antiepileptics&nbsp;(substances used to prevent and relieve seizures)<\/li><li>barbiturates&nbsp;(substances commonly used for insomnia)<\/li><li>dopaminergic&nbsp;agonists&nbsp;(substances such as&nbsp;L-dopa&nbsp;, bromocriptine)<\/li><li>neuroleptics&nbsp;(substances used in the treatment of mental illness)<\/li><li>oral&nbsp;anticoagulants<\/li><\/ul>\n\n\n\n<p>If you are hospitalized, tell your doctor that you are taking Memantine Ratiopharm.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Memantine ratiopharm with food and drink<\/h2>\n\n\n\n<p>You should tell your doctor if you have recently changed or intend to change your diet significantly (eg from a regular diet to a vegetarian diet only) or if you suffer from a condition of&nbsp;renal&nbsp;tubular&nbsp;acidosis&nbsp;(RTA, an excess on acid-forming substances in the blood due to kidney dysfunction (impaired kidney function)) or severe urinary tract infections, as your doctor may need to adjust the&nbsp;dose&nbsp;of your medicine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<\/p>\n\n\n\n<p>The use of memantine in pregnant women is not recommended.<\/p>\n\n\n\n<p>Women taking Memantine Ratiopharm should not breastfeed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Your doctor will tell you if your illness allows you to drive and use machines safely.<br>Memantine Ratiopharm may also alter your ability to react, making it unsuitable to drive or use machines.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Memantine ratiopharm contains lactose and soy lecithin<\/h2>\n\n\n\n<p>This medicine contains\u00a0lactose.\u00a0If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.<br>This medicine contains soy lecithin.\u00a0If you are allergic to peanuts or soy, do not use this medicine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to use Memantine ratiopharm<\/h2>\n\n\n\n<p>Memantine Ratiopharm packaging for the start of treatment should only be used at the beginning of treatment with Memantine Ratiopharm.<\/p>\n\n\n\n<p>Always use this medicine exactly as your doctor has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p><strong>Dosage<\/strong><br>The recommended treatment dose of 20 mg per day is achieved by gradually increasing the\u00a0dose\u00a0of Memantine Ratiopharm during the first 3 weeks of treatment.\u00a0Take one tablet once a day.<\/p>\n\n\n\n<p>Week 1 (day 1-7):<br>Take a 5 mg tablet once a day (white to off-white, capsule-shaped, biconvex, smooth on one side, and debossed with \u201c5\u201d on the other side) for 7 days.<\/p>\n\n\n\n<p>Week 2 (day 8-14):<br>Take a 10 mg tablet once a day (white to off-white, capsule-shaped, biconvex, with a scoreline on one side and debossed with \u201c10\u201d on the other side) for 7 days.<\/p>\n\n\n\n<p>Week 3 (day 15-21):<br>Take one 15 mg tablet once daily (white to off-white, capsule-shaped, biconvex, smooth on one side, and debossed with \u201c15\u201d on the other side) for 7 days.<\/p>\n\n\n\n<p>Week 4 (day 22-28):<br>Take a 20 mg tablet once daily (white to off-white, capsule-shaped, biconvex, with a scoreline on one side and debossed with \u201c20\u201d on the other side) for 7 days.<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td>week 1<\/td><td>5 mg tablet<\/td><\/tr><tr><td>week 2<\/td><td>10 mg tablet<\/td><\/tr><tr><td>week 3<\/td><td>15 mg tablet<\/td><\/tr><tr><td>week 4 and thereafter<\/td><td>20 mg tablets once a day<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p><strong>Maintenance<\/strong><br>dose The recommended daily dose is 20 mg once a day.&nbsp;To continue treatment, consult your doctor.<\/p>\n\n\n\n<p><strong>Dosage&nbsp;in patients with renal impairment<\/strong><br>If you have renal impairment, your doctor will prescribe a&nbsp;dose&nbsp;that suits your condition.&nbsp;In this case, your doctor should examine your kidney function at certain intervals.<\/p>\n\n\n\n<p><strong>Administration<\/strong><br>Memantine Ratiopharm should be taken orally once a day.\u00a0For you to benefit from your medicine, you must take it regularly every day at the same time of day.<br>The tablets should be swallowed with a little water.\u00a0The tablets can be taken with or without food.<\/p>\n\n\n\n<p><strong>Treatment<\/strong><br>time Continue to take Memantine Ratiopharm for as long as you benefit from it.\u00a0Your doctor should regularly evaluate your treatment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you take more Memantine ratiopharm than you should<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>In general, it should not harm you if you take too much Memantine ratiopharm.&nbsp;You may experience increased symptoms as described in section 4. &#8220;Possible side effects&#8221;.<\/li><li>If you are taking a large overdose of Memantine ratiopharm, contact your doctor or seek medical advice, as you may need care.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to take Memantine ratiopharm<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>If you find that you have forgotten to take your&nbsp;dose of&nbsp;Memantine ratiopharm, wait and take your next&nbsp;dose&nbsp;at the usual time.<\/li><li>Do not take a double&nbsp;dose&nbsp;to make up for a forgotten&nbsp;dose&nbsp;.<\/li><\/ul>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p>In general, the&nbsp;side effects&nbsp;observed are mild to moderate.<\/p>\n\n\n\n<p><em>Common (affects 1 to 10 users in 100):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Headache, drowsiness, constipation, elevated liver function tests, dizziness, balance disorders, shortness of breath, high&nbsp;blood pressure&nbsp;and drug hypersensitivity<\/li><\/ul>\n\n\n\n<p><em>Uncommon (affects 1 to 10 users in 1,000):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Fatigue, fungal infections, confusion, hallucinations, vomiting, gait disorders,&nbsp;heart failure&nbsp;and blood clots in veins<\/li><\/ul>\n\n\n\n<p><em>Very rare (affects less than 1 user in 10,000):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Cramps<\/li><\/ul>\n\n\n\n<p><em>No known frequency (can not be calculated from the available data):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Pancreatitis, hepatitis&nbsp;and&nbsp;psychotic reactions<\/li><\/ul>\n\n\n\n<p>Alzheimer&#8217;s disease\u00a0has been associated with depression, suicidal ideation, and\u00a0suicide.\u00a0These events have been reported in patients treated with memantine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Memantine ratiopharm<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the carton and blister after EXP. The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>Do not store above 25 \u00b0 C.<\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the pack and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<p>The active substance is memantine hydrochloride.<br>Each film-coated tablet contains 5 mg memantine hydrochloride equivalent to 4.15 mg memantine.<br>Each film-coated tablet contains 10 mg memantine hydrochloride equivalent to 8.31 mg memantine.<br>Each film-coated tablet contains 15 mg memantine hydrochloride equivalent to 12.46 mg memantine.<br>Each film-coated tablet contains 20 mg memantine hydrochloride equivalent to 16.62 mg memantine.<\/p>\n\n\n\n<p>The other ingredients are:<br><em>Tablet core<\/em><br>Microcrystalline cellulose (E 460), pregelatinized\u00a0starch\u00a0(E 1404), anhydrous\u00a0lactose,\u00a0colloidal\u00a0anhydrous silica (E 551), magnesium stearate (E 470b).<br><em>Coating<\/em><br>Polysorbate 80 (E 433), polyvinyl alcohol (E 1203), titanium dioxide (E 171), talc (E 553b), soy lecithin (E 322), xanthan gum (E 415).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and contents of the pack<\/h2>\n\n\n\n<p>The 5 mg film-coated tablets are white to off-white, capsule-shaped, biconvex tablets that are smooth on one side and debossed with \u201c5\u201d on the other side.<br>The 10 mg film-coated tablets are white to off-white, capsule-shaped, biconvex tablets with a scoreline on one side and debossed with \u201c10\u201d on the other side.<br>The 15 mg film-coated tablets are white to off-white, capsule-shaped, biconvex tablets that are smooth on one side and debossed with \u201c15\u201d on the other side.<br>The 20 mg film-coated tablets are white to off-white, capsule-shaped, biconvex tablets with a scoreline on one side and debossed with \u201c20\u201d on the other side.<\/p>\n\n\n\n<p>Memantine ratiopharm is available in packs of 28 (7 + 7 + 7 + 7) film-coated tablets.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorisation Holder<\/h2>\n\n\n\n<p>ratiopharm GmbH<br>Graf-Arco-Stra\u00dfe 3<br>89079 Ulm<br>Germany<\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><br>Merckle GmbH<br>Ludwig-Merckle-Stra\u00dfe 3<br>89143 Blaubeuren<br>Germany<\/p>\n\n\n\n<p>TEVA Pharmaceutical Works Private Limited Company<br>Pallagi from 13, 4042 Debrecen<br>Hungary<\/p>\n\n\n\n<p>HBM Pharma sro<br>Slabinsk\u00e1 30, 03680 Martin<br>Slovakia<\/p>\n\n\n\n<p>Contact the representative of the marketing authorization holder to find out more about this medicine:<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td><strong>Belgium \/ Belgique \/ Belgien<\/strong>Teva Pharma Belgium NV \/ SA \/ AGTel: +32 3 820 73 73<\/td><td><strong>Lithuania<\/strong>UAB &#8220;Sicor Biotech&#8221;Tel: +370 5 266 0203<\/td><\/tr><tr><td><strong>Bulgaria<\/strong>Teva Pharmaceuticals Bulgaria \u0415\u041e\u041e\u0414Tel: +359 2 489 95 82<\/td><td><strong>Luxembourg \/ Luxemburg<\/strong>ratiopharm GmbHGermany \/ GermanyTel: +49 731 402 02<\/td><\/tr><tr><td><strong>Czech Republic<\/strong>Teva Pharmaceuticals CR, sroTel: +420 251 007 111<\/td><td><strong>Hungary<\/strong>Teva Gy\u00f3gyszergy\u00e1r Zrt.Tel .: +36 1 288 64 00<\/td><\/tr><tr><td><strong>Denmark<\/strong>Teva Denmark A \/ STel: +45 44 98 55 11<\/td><td><strong>Malta<\/strong>Teva Pharmaceuticals IrelandL-IrelandTel: +353 51 321 740<\/td><\/tr><tr><td><strong>Germany<\/strong>ratiopharm GmbHTel: +49 731 402 02<\/td><td><strong>The Netherlands<\/strong>Teva Nederland BVTel: +31 800 0228 400<\/td><\/tr><tr><td><strong>Eesti<\/strong>UAB &#8220;Sicor Biotech&#8221; Eesti subsidiaryTel: +372 661 0801<\/td><td><strong>Norway<\/strong>Teva Norway ASTel: +47 66 77 55 90<\/td><\/tr><tr><td><strong>Greece<\/strong>Teva \u0391\u03bb\u03bb\u03ac\u03c2 \u0391.\u0395.:\u0397\u03bb: +30 210 72 79 099<\/td><td><strong>Austria<\/strong>ratiopharm Arzneimittel Vertriebs \u2011 GmbHTel: +43 1 97 007 0<\/td><\/tr><tr><td><strong>Spain<\/strong>ratiopharm Spain, SATel: +34 91 567 29 70<\/td><td><strong>Poland<\/strong>Teva Pharmaceuticals Polska Sp.&nbsp;z ooTel .: +48 22 345 93 00<\/td><\/tr><tr><td><strong>France<\/strong>Teva HealthTel: +33 1 55 91 78 00<\/td><td><strong>Portugal<\/strong>ratiopharm, Commerce and Industry of Pharmaceutical Products, LdaTel: +351 21 476 75 50<\/td><\/tr><tr><td><strong>Croatia<\/strong>Pliva Hrvatska dooTel: + 385 1 37 20 000<\/td><td><strong>Romania<\/strong>Teva Pharmaceuticals SRLTel: +40 21 230 65 24<\/td><\/tr><tr><td><strong>Ireland<\/strong>Teva Pharmaceuticals IrelandTel: +353 51 321740<\/td><td><strong>Slovenia<\/strong>Pliva Ljubljana dooTel: +386 1 58 90 390<\/td><\/tr><tr><td><strong>Iceland<\/strong>Alvogen ehf.Phone: +354 522 2900<\/td><td><strong>Slovak Republic<\/strong>TEVA Pharmaceuticals Slovakia sroTel: +421 2 57 26 79 11<\/td><\/tr><tr><td><strong>Italy<\/strong>Teva Italia SrlTel: +39 02 89 17 98 1<\/td><td><strong>Finland \/ Finland<\/strong>ratiopharm OyPuh \/ Tel: +358 20 180 5900<\/td><\/tr><tr><td><strong>.\u03a0\u03c1\u03bf\u03c2<\/strong>Teva \u0391\u03bb\u03bb\u03ac\u03c2 \u0391.\u0395., .\u03bb\u03bb\u03ac\u03b4\u03b1:\u0397\u03bb: +30 210 72 79 099<\/td><td><strong>Sweden<\/strong>Teva Sweden ABTel: +46 42 12 11 00<\/td><\/tr><tr><td><strong>Latvia<\/strong>UAB &#8220;Sicor Biotech&#8221; affiliates Latvij\u0101Tel: +371 673 23 666<\/td><td><strong>United Kingdom<\/strong>Teva UK LimitedTel: +44 1977 628500<\/td><\/tr><\/tbody><\/table><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>Memantine ratiopharm contains the active substance memantine hydrochloride. It belongs to a group of medicines known as anti-dementia medicines.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,15580],"tags":[4842,4844,17042,17046,17045,4843,17043,16804,17041,17044],"class_list":["post-17560","post","type-post","status-publish","format-standard","hentry","category-medicines","category-m","tag-memantine-hydrochloride","tag-memantine-hydrochloride-side-effects","tag-memantine-ratiopharm","tag-memantine-ratiopharm-side-effects","tag-memantine-ratiopharm-tabelt","tag-what-is-memantine-hydrochloride","tag-what-is-memantine-ratiopharm","tag-what-memantine-hydrochloride-is-used-for","tag-what-memantine-hydrochloride-tablet","tag-what-memantine-ratiopharm-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/17560","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=17560"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/17560\/revisions"}],"predecessor-version":[{"id":17601,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/17560\/revisions\/17601"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=17560"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=17560"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=17560"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}