10 mg, 20 mg Film-coated tablets
Memantine hydrochloride<\/p>\n\n\n\n
How Memantine LEK works<\/strong><\/p>\n\n\n\n Memantine LEK belongs to a group of medicines known as anti-dementia medicines. Memory loss in Alzheimer’s disease is due to a disturbance of message signals in the brain. The brain contains so-called NMDA receptors (N-methyl-D-aspartate) that are involved in the transmission of nerve signals that are important for learning and memory. Memantine LEK belongs to a group of medicines called NMDA receptor antagonists. Memantine LEK acts on these NMDA receptors by improving the transmission of nerve signals and memory.<\/p>\n\n\n\n What Memantine LEK is used for<\/strong><\/p>\n\n\n\n Memantine LEK is used to treat patients with moderate to severe\u00a0Alzheimer’s disease.<\/p>\n\n\n\n In these situations, treatment should be closely monitored and the clinical benefit of Memantine LEK should be regularly assessed by your physician.<\/p>\n\n\n\n If you suffer from impaired kidney function (kidney problems), your doctor should closely monitor your kidney function and, if necessary, adjust the memantine doses accordingly.<\/p>\n\n\n\n Concomitant use of drugs containing amantadine (for the treatment of\u00a0Parkinson’s disease\u00a0), ketamine (a substance commonly used as an anesthetic), dextromethorphan (generally used to treat cough), and other NMDA\u00a0antagonists\u00a0should be avoided.<\/p>\n\n\n\n You should tell your doctor if you have recently changed or intend to change your diet significantly (eg from a regular diet to a vegetarian diet only) or if you suffer from a condition of renal tubular acidosis (RTA, an excess on acid-forming substances in the blood due to kidney dysfunction (impaired kidney function)) or severe urinary tract infection ( cataracts ), as your doctor may need to adjust the dose of your medicine.<\/p>\n\n\n\n Memantine LEK is not recommended for children and adolescents under 18 years of age.<\/p>\n\n\n\n Tell your doctor or pharmacist if you are taking or have recently taken or might take any other medicines. This includes medicines, including over-the-counter ones.<\/p>\n\n\n\n Memantine LEK may particularly affect the effects of the following medicines and these doses may need to be changed by your doctor:<\/p>\n\n\n\n If you are hospitalized, tell your doctor that you are taking Memantine LEK.<\/p>\n\n\n\n If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<\/p>\n\n\n\n The use of memantine in pregnant women is not recommended.<\/p>\n\n\n\n Women taking Memantine LEK should not breastfeed.<\/p>\n\n\n\n Your doctor will tell you if your illness allows you to drive and use machines safely. Memantine LEK may also alter your ability to react, making it unsuitable to drive or use machines.<\/p>\n\n\n\n Always take this medicine exactly as your doctor or pharmacist has told you. Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n Dosage<\/strong><\/p>\n\n\n\n The recommended\u00a0dose of\u00a0Memantine LEK for adults and elderly patients is 20 mg once a day.\u00a0To reduce the risk of\u00a0side effects, this\u00a0dose\u00a0is achieved gradually through the following daily treatment schedule:<\/p>\n\n\n\n The usual starting dose is half a 10 mg tablet once a day (1 x 5 mg) for the first week. This is increased to one 10 mg tablet once a day (1 x 10 mg) during the second week and to 1 and a half 10 mg tablets once a day during the third week. The recommended maintenance dose is 20 mg once daily, which is reached at the beginning of the fourth week.<\/p>\n\n\n\n Dosage in patients with renal impairment<\/strong><\/p>\n\n\n\n If you have impaired kidney function, your doctor will prescribe a dose that suits your condition. In this case, your doctor should examine your kidney function at certain intervals.<\/p>\n\n\n\n Administration<\/strong><\/p>\n\n\n\n Memantine LEK should be taken orally once a day.\u00a0For you to benefit from your medicine, you must take it regularly every day at the same time of day.\u00a0The tablets should be swallowed with a little water.\u00a0The tablets can be taken with or without food.<\/p>\n\n\n\n Treatment time<\/strong><\/p>\n\n\n\n Continue to take Memantine LEK for as long as you benefit from it. Your doctor should regularly evaluate your treatment.<\/p>\n\n\n\n – In general, it should not hurt you if you take too much Memantine LEK. You may experience increased symptoms as described in section 4. “Possible side effects”.<\/p>\n\n\n\n – If you are taking a large overdose of Memantine LEK, contact your doctor or medical advice, as you may need care.<\/p>\n\n\n\n – If you find that you have forgotten to take your dose of Memantine LEK, wait and take your next dose at the usual time.<\/p>\n\n\n\n – Do not take a double\u00a0dose\u00a0to make up for a forgotten\u00a0dose.<\/p>\n\n\n\n If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n In general, the side effects observed are mild to moderate.<\/p>\n\n\n\n Common (may affect up to 1 in 10 people):<\/em><\/p>\n\n\n\n \u2022 Headache, drowsiness, constipation, elevated liver function tests, dizziness, balance disorders, shortness of breath, high\u00a0blood pressure,\u00a0and drug hypersensitivity<\/p>\n\n\n\n Uncommon (may affect up to 1 in 100 people):<\/em><\/p>\n\n\n\n \u2022 Fatigue, fungal infections, confusion, hallucinations, vomiting, gait disorders,\u00a0heart failure,\u00a0and blood clots in veins<\/p>\n\n\n\n Very rare (may affect up to 1 in 10,000 people):<\/em><\/p>\n\n\n\n \u2022 Cramps<\/p>\n\n\n\n Has been reported (occurs in an unknown number of users):<\/em><\/p>\n\n\n\n \u2022 Pancreatitis, hepatitis,\u00a0and\u00a0psychotic reactions<\/p>\n\n\n\n Alzheimer’s disease\u00a0has been associated with depression, suicidal ideation, and\u00a0suicide.\u00a0These events have been reported in patients treated with Memantine LEK.<\/p>\n\n\n\n If you get\u00a0any side effects, talk to your doctor or pharmacist.\u00a0This also applies to any\u00a0side effects\u00a0not mentioned in this information.<\/p>\n\n\n\n Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n Do not use this medicine after the expiry date which is stated on the carton and blister after EXP. or EXP. The expiration date is the last day of the specified month.<\/p>\n\n\n\n No special storage instructions.<\/p>\n\n\n\n Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.<\/p>\n\n\n\n The active substance is memantine hydrochloride.<\/p>\n\n\n\n Each film-coated tablet contains 10 mg memantine hydrochloride equivalent to 8.31 mg memantine.<\/p>\n\n\n\n Each film-coated tablet contains 20 mg memantine hydrochloride equivalent to 16.62 mg memantine.<\/p>\n\n\n\n Other ingredients are:<\/p>\n\n\n\n Tablet core: microcrystalline cellulose, croscarmellose sodium,\u00a0colloidal\u00a0anhydrous silica, and magnesium stearate.<\/p>\n\n\n\n 10 mg:<\/p>\n\n\n\n Tablet coating: polyvinyl alcohol, titanium dioxide (E171), talc, macrogol 3350, and yellow iron oxide (E 172)<\/p>\n\n\n\n 20 mg:<\/p>\n\n\n\n Tablet coating: polyvinyl alcohol, titanium dioxide (E171), talc, macrogol 3350, yellow iron oxide (E 172), and red iron oxide (E 172)<\/p>\n\n\n\n Memantine LEK 10 mg film-coated tablets are yellow, oval with a scoreline on one side.<\/p>\n\n\n\n The tablet can be divided into two equal parts.<\/p>\n\n\n\n Memantine LEK 20 mg film-coated tablets are pale red, oval with a scoreline on one side.<\/p>\n\n\n\n The notch is not intended for splitting the tablet<\/p>\n\n\n\n Memantine LEK 10 mg film-coated tablets are available as PVC \/ PVDC \u2013 Aluminum blister packs of 30, 42, 50, 56, 98, and 112 tablets.<\/p>\n\n\n\n Memantine LEK 10 mg film-coated tablets are available as PVC \/ PVDC \u2013 Aluminum blister packs of 28, 30, 42, 56, and 98 tablets.<\/p>\n\n\n\n Not all pack sizes may be marketed.<\/p>\n\n\n\n Marketing Authorisation Holder:<\/em><\/p>\n\n\n\n Pharmathen SA, 6, Dervenakion str., 15351 Pallini, Attiki, Greece<\/p>\n\n\n\n Manufacturer:<\/em><\/p>\n\n\n\n Pharmathen SA, 6, Dervenakion str., 15351 Pallini, Attiki, Greece<\/p>\n\n\n\n or<\/p>\n\n\n\n Pharmathen International SA, Industrial Park Sapes, Rodopi Prefecture, Block No 5, Rodopi 69300, Greece<\/p>\n\n\n\n or<\/p>\n\n\n\n J. Uriach y Compa\u00f1\u00eda, SA, Av. Cam\u00ed Reial 51-57, 08184 Palau-solit\u00e0 i Plegamans, Spanien<\/p>\n\n\n\n Further information on this medicine can be obtained from the representative of the marketing authorization holder.<\/p>\n\n\n\n Memantine LEK belongs to a group of medicines known as anti-dementia medicines. Memory loss in Alzheimer’s disease is due to a disturbance of message signals in the brain. The brain contains so-called NMDA receptors (N-methyl-D-aspartate) that are involved in the transmission of nerve signals that are important for learning and memory. Memantine LEK belongs to a group of medicines called NMDA receptor antagonists. Memantine LEK acts on these NMDA receptors by improving the transmission of nerve signals and memory.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,15580],"tags":[16805,17057,4842,4844,4845,17052,17056,17055,4843,17053,16804,17054],"class_list":["post-17555","post","type-post","status-publish","format-standard","hentry","category-medicines","category-m","tag-benefits-of-memantine-hydrochloride","tag-benefits-of-memantine-lek","tag-memantine-hydrochloride","tag-memantine-hydrochloride-side-effects","tag-memantine-hydrochloride-tablet","tag-memantine-lek","tag-memantine-lek-side-effects","tag-memantine-lek-tablet","tag-what-is-memantine-hydrochloride","tag-what-is-memantine-lek","tag-what-memantine-hydrochloride-is-used-for","tag-what-memantine-lek-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/17555","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=17555"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/17555\/revisions"}],"predecessor-version":[{"id":17603,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/17555\/revisions\/17603"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=17555"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=17555"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=17555"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}What you need to know before using Memantine LEK<\/h2>\n\n\n\n
Do not use Memantine LEK<\/h2>\n\n\n\n
Warnings and cautions<\/h2>\n\n\n\n
Children and young people<\/h2>\n\n\n\n
Other medicines and Memantine LEK<\/h2>\n\n\n\n
Pregnancy, breastfeeding and fertility<\/h2>\n\n\n\n
Driving and using machines<\/h2>\n\n\n\n
3. How to use Memantine LEK<\/h2>\n\n\n\n
Week 1<\/td> Half a 10 mg tablet<\/td><\/tr> Week 2<\/td> One 10 mg tablet<\/td><\/tr> Week 3<\/td> One and a half 10 mg tablets<\/td><\/tr> Week 4 and beyond<\/td> Two 10 mg tablets or one 20 mg tablet once a day<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n If you use more Memantine LEK than you should <\/h2>\n\n\n\n
If you forget to use Memantine LEK<\/h2>\n\n\n\n
Possible side effects<\/h2>\n\n\n\n
How to store Memantine LEK<\/h2>\n\n\n\n
Contents of the pack and other information<\/h2>\n\n\n\n
Content declaration<\/h2>\n\n\n\n
What the medicine looks like and contents of the pack<\/h2>\n\n\n\n
Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n
Belgium \/ Belgique \/ Belgien<\/strong>Sandoz nv \/ saTel: +32 2 722 97 81<\/td> Luxembourg \/ Luxemburg<\/strong>Sandoz nv \/ saTel: + 32 2 722 97 81<\/td><\/tr> Bulgaria<\/strong>Sandoz dd Representative officeTel: + 359 2 970 47 47<\/td> Hungary<\/strong>Sandoz Hungary Kft.Tel .: + 36 1 430 2896<\/td><\/tr> Czech Republic<\/strong>Sandoz sroTel: + +420 221 421 658<\/td> Malta<\/strong>Cherubino LTDTel: + 356 21 343 270<\/td><\/tr> Denmark<\/strong>Sandoz A \/ STel: + 45 6395 1000<\/td> The Netherlands<\/strong>Sandoz BVTel: + 31 (0) 36 5241600<\/td><\/tr> Germany<\/strong>Sandoz Pharmaceuticals GmbHTel: + 49 08024 902-4513<\/td> Norway<\/strong>Sandoz A \/ STel: + 45 6395 1000<\/td><\/tr> Estonia (Estonia)<\/strong>Sandoz dd EstoniaTel: + 372 6652405<\/td> Austria<\/strong>Sandoz GmbHTel: + 43 5338 200<\/td><\/tr> Greece<\/strong>Sambrook Pharmaceuticals Med SA800 110 0333 (toll free) \/ + 30-210-8194280<\/td> Poland<\/strong>Lek SATel .: + 48\/22\/549 15 43, +48 \/ 22\/549 07 24<\/td><\/tr> Spain<\/strong>Sandoz Pharmac\u00e9utica, SATel: + 34 91 740 12 92<\/td> Portugal<\/strong>Sandoz Pharmac\u00eautica Lda.Tel: + 351 21 000 87 81<\/td><\/tr> France<\/strong>SandozTel: +33 1 49 64 48 21<\/td> Romania<\/strong>Sandoz SRL RomaniaTel: + 40 21 407 51 83<\/td><\/tr> Ireland<\/strong>ROWEX LTDTel: + 353 27 50077<\/td> Slovenia<\/strong>Lek Pharmaceuticals ddTel: + 386 1 580 3327<\/td><\/tr> Iceland<\/strong>Sandoz A \/ STel: + 45 6395 1000<\/td> Slovak Republic<\/strong>Sandoz dd organizacna zlozkaTel: + 421-2 \/ 48 200 600<\/td><\/tr> Italy<\/strong>Sandoz SpATel: + 39 02 96 54 3483<\/td> Finland \/ Finland<\/strong>Sandoz A \/ SPuh \/ Tel: + 45 6395 1000<\/td><\/tr> .\u03a0\u03c1\u03bf\u03c2<\/strong>PTHadjigeorgiou Co Ltd:\u0397\u03bb: + 357 – 25372425<\/td> Sweden<\/strong>Sandoz A \/ STel: + 45 6395 1000<\/td><\/tr> Latvia<\/strong>Sandoz dd representative office Latvia.Tel: + 371 6789 2006<\/td> United Kingdom<\/strong>Sandoz LimitedTel: + 44 1276 698020<\/td><\/tr> Lithuania<\/strong>Sandoz Pharmaceuticals ddTel: + 370 5 2636 037<\/td><\/tr><\/tbody><\/table><\/figure>\n","protected":false},"excerpt":{"rendered":"