5, 10, 15, and 20 mg\u00a0film-coated tablet
memantine hydrochloride<\/p>\n\n\n\n
How Memantine Accord works<\/strong><\/p>\n\n\n\n Memantine Accord contains the active substance memantine hydrochloride.<\/p>\n\n\n\n Memantine Accord belongs to a group of medicines known as anti-dementia medicines. Memory loss in Alzheimer’s disease is due to a disturbance of message signals in the brain. The brain contains so-called NMDA receptors (N-methyl-D-aspartate) that are involved in the transmission of nerve signals that are important for learning and memory. Memantine Accord belongs to a group of medicines called NMDA receptor antagonists. Memantine Accord acts on these NMDA receptors by improving the transmission of nerve signals and memory.<\/p>\n\n\n\n What Memantine Accord is used for<\/strong><\/p>\n\n\n\n Memantine Accord is used to treat patients with moderate to severe\u00a0Alzheimer’s disease.<\/p>\n\n\n\n Talk to your doctor or pharmacist before taking Memantine Accord<\/p>\n\n\n\n In these situations, treatment should be closely monitored and the clinical benefit of Memantine Accord should be regularly assessed by your physician.<\/p>\n\n\n\n If you suffer from impaired kidney function (kidney problems), your doctor should closely monitor your kidney function and, if necessary, adjust the memantine doses accordingly.<\/p>\n\n\n\n Concomitant use of drugs containing amantadine (for the treatment of\u00a0Parkinson’s disease\u00a0), ketamine (a substance commonly used as an anesthetic), dextromethorphan (generally used to treat cough), and other NMDA\u00a0antagonists\u00a0should be avoided.<\/p>\n\n\n\n Memantine Accord is not recommended for children and adolescents under 18 years of age<\/p>\n\n\n\n Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.<\/p>\n\n\n\n Memantine Accord may particularly affect the effects of the following medicines and these doses may need to be changed by your doctor:<\/p>\n\n\n\n amantadine, ketamine, dextromethorphan<\/p>\n\n\n\n dantrolene, baclofen<\/p>\n\n\n\n cimetidine, ranitidine, procainamide , quinidine , quinine, nicotine<\/p>\n\n\n\n hydrochlorothiazide (or any combination with hydrochlorothiazide)<\/p>\n\n\n\n anticholinergics (substances commonly used to treat movement disorders or intestinal cramps)<\/p>\n\n\n\n antiepileptics (substances used to prevent and relieve seizures)<\/p>\n\n\n\n barbiturates (substances commonly used for insomnia)<\/p>\n\n\n\n dopaminergic\u00a0agonists\u00a0(substances such as\u00a0L-dopa, bromocriptine)<\/p>\n\n\n\n neuroleptics (substances used in the treatment of mental illness)<\/p>\n\n\n\n oral anticoagulants<\/p>\n\n\n\n If you are hospitalized, tell your doctor that you are taking Memantine Accord.<\/p>\n\n\n\n You should tell your doctor if you have recently changed or intend to change your diet significantly (eg from a regular diet to a vegetarian diet only) or if you suffer from a condition of renal tubular acidosis (RTA, an excess on acid-forming substances in the blood due to kidney dysfunction (renal impairment)) or severe urinary tract infections ( cataracts ), as your doctor may need to adjust the dose of your medicine.<\/p>\n\n\n\n If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<\/p>\n\n\n\n Pregnancy<\/em> <\/p>\n\n\n\n The use of memantine in pregnant women is not recommended.<\/p>\n\n\n\n Breast-feeding<\/em> <\/p>\n\n\n\n Women taking Memantine Accord should not breastfeed.<\/p>\n\n\n\n Your doctor will tell you if your illness allows you to drive and use machines safely. Memantine Accord may also alter your responsiveness, making it unsuitable to drive or use machines.<\/p>\n\n\n\n This medicine contains\u00a0lactose.\u00a0If you have previously been told by your doctor that you have an intolerance to some sugars, contact your doctor before using this medicine.\u00a0Your doctor will advise you.<\/p>\n\n\n\n The Memantine Accord package for initiating treatment should only be used at the beginning of treatment with Memantine Accord.<\/p>\n\n\n\n Always use this medicine exactly as your doctor has told you. If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n Dosage<\/p>\n\n\n\n The recommended treatment dose of 20 mg per day is achieved by gradually increasing the Memantine Accord dose during the first 3 weeks of treatment. The treatment schedule is also indicated on the package for initiating treatment. Take one tablet once a day.<\/p>\n\n\n\n Week 1 (days 1-7):<\/p>\n\n\n\n Take one 5 mg tablet once a day (white) for 7 days.<\/p>\n\n\n\n Week 2 (days 8-14):<\/p>\n\n\n\n Take a 10 mg tablet once a day (white with a scoreline) for 7 days.<\/p>\n\n\n\n Week 3 (day 15-21):<\/p>\n\n\n\n Take one 15 mg tablet once a day (orange to gray-orange) for 7 days.<\/p>\n\n\n\n Week 4 (day 22-28):<\/p>\n\n\n\n Take a 20 mg tablet once a day (pale red to gray-red, with break marks) for 7 days.<\/p>\n\n\n\n Maintenance dose<\/p>\n\n\n\n The recommended daily dose is 20 mg once a day.<\/p>\n\n\n\n To continue treatment, consult your doctor.<\/p>\n\n\n\n Dosage in patients with renal impairment<\/p>\n\n\n\n If you have impaired kidney function, your doctor will prescribe a dose that suits your condition. In this case, your doctor should examine your kidney function at certain intervals.<\/p>\n\n\n\n How to take the medicine<\/p>\n\n\n\n Memantine Accord should be taken orally once a day.\u00a0For you to benefit from your medicine, you must take it regularly every day at the same time of day.\u00a0The tablets should be swallowed with a little water.\u00a0The tablets can be taken with or without food.<\/p>\n\n\n\n Treatment time<\/p>\n\n\n\n Continue to take Memantine Accord for as long as you benefit from it. Your doctor should regularly evaluate your treatment.<\/p>\n\n\n\n If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n Like all medicines, Memantine Accord can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n In general, the side effects observed are mild to moderate.<\/p>\n\n\n\n Common (may affect up to 1 in 10 people):<\/em><\/p>\n\n\n\n Uncommon (may affect up to 1 in 100 people):<\/em><\/p>\n\n\n\n Very rare ( <\/em>may affect up to 1 in 10,000 people):<\/em><\/p>\n\n\n\n Has been reported (occurs in an unknown number of users):<\/em><\/p>\n\n\n\n Alzheimer’s\u00a0disease has been associated with depression, suicidal ideation, and\u00a0suicide.\u00a0These events have been reported in patients treated with memantine.<\/p>\n\n\n\n Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n Do not use this medicine after the expiry date which is stated on the carton and blister after EXP. The expiration date is the last day of the specified month.<\/p>\n\n\n\n No special storage instructions.<\/p>\n\n\n\n Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.<\/p>\n\n\n\n The active substance is memantine hydrochloride. Each film-coated tablet contains 5\/10\/15\/20 mg memantine hydrochloride equivalent to 4.15 \/ 8.31 \/ 12.46 \/ 16.62 mg memantine.<\/p>\n\n\n\n The other ingredients for Memantine Accord are\u00a0lactose monohydrate, microcrystalline cellulose,\u00a0colloidal\u00a0anhydrous silica, crospovidone, magnesium stearate, all in the tablet core;\u00a0hypromellose, polysorbate 80, maktrogol 400, titanium dioxide (E 171) and for Memantine Accord 15 mg and Memantine Accord 20 mg film-coated tablets yellow and red iron oxide (E 172) all in the tablet coating.<\/p>\n\n\n\n Memantine Accord 5 mg coated tablets are white, oblong, marked \u201cMT\u201d on one side and marked \u201c5\u201d on the other side.<\/p>\n\n\n\n Memantine Accord 10 mg film-coated tablets are white, oblong,\u00a0coated\u00a0tablets with a scoreline, marked \u201cMT\u201d divided by the scoreline on one side and \u201c10\u201d divided by the scoreline, on the other side.\u00a0The tablet can be divided into two equal\u00a0doses.<\/p>\n\n\n\n Memantine Accord 15 mg film-coated tablets are orange to gray-orange, oblong, coated tablets, labeled \u201cMT\u201d on one side and labeled \u201c15\u201d on the other.<\/p>\n\n\n\n Memantine Accord 20 mg film-coated tablets are pale red to gray-red, oblong,\u00a0coated\u00a0tablets with a scoreline, marked \u201cMT\u201d divided by the scoreline on one side and \u201c20\u201d divided by the scoreline on the other side.\u00a0The tablet can be divided into two equal\u00a0doses.<\/p>\n\n\n\n One pack of initiation of treatment contains 28 tablets in 4 blisters with 7 tablets of Memantine Accord 5 mg, 7 tablets of Memantine Accord 10 mg, 7 tablets of Memantine Accord 15 mg, and 7 tablets of Memantine Accord 20 mg.<\/p>\n\n\n\n Marketing Authorisation Holder<\/strong><\/p>\n\n\n\n Accord Healthcare SLU<\/p>\n\n\n\n World Trade Center, Moll de Barcelona, \u200b\u200bs \/ n,<\/p>\n\n\n\n Edifici Est 6\u00aa planta,<\/p>\n\n\n\n 08039 Barcelona,<\/p>\n\n\n\n Spain<\/p>\n\n\n\n Manufacturer<\/strong><\/p>\n\n\n\n Deloris Pharmaceuticals Ltd<\/p>\n\n\n\n 17, Athinon Street<\/p>\n\n\n\n Ergates Industrial Area, 2643 Nicosia<\/p>\n\n\n\n Cyprus<\/p>\n\n\n\n Accord Healthcare Polska Sp.z oo,<\/p>\n\n\n\n ul. Lutomierska 50,95-200 Pabianice, Poland<\/p>\n","protected":false},"excerpt":{"rendered":" Memantine Accord contains the active substance memantine hydrochloride.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,15580],"tags":[17063,16805,17058,17062,17061,4842,4844,4845,17059,4843,17060,16804],"class_list":["post-17554","post","type-post","status-publish","format-standard","hentry","category-medicines","category-m","tag-benefits-of-memantine-accord","tag-benefits-of-memantine-hydrochloride","tag-memantine-accord","tag-memantine-accord-side-effects","tag-memantine-accord-tablet","tag-memantine-hydrochloride","tag-memantine-hydrochloride-side-effects","tag-memantine-hydrochloride-tablet","tag-what-is-memantine-accord","tag-what-is-memantine-hydrochloride","tag-what-memantine-accord-is-used-for","tag-what-memantine-hydrochloride-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/17554","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=17554"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/17554\/revisions"}],"predecessor-version":[{"id":17604,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/17554\/revisions\/17604"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=17554"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=17554"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=17554"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}What you need to know before taking Memantine Accord<\/h2>\n\n\n\n
Do not use Memantine Accord<\/h2>\n\n\n\n
Warnings and cautions<\/h2>\n\n\n\n
Children and young people<\/h2>\n\n\n\n
Other medicines and Memantine Accord<\/h2>\n\n\n\n
Memantine Accord with food and drink<\/h2>\n\n\n\n
Pregnancy and breastfeeding<\/h2>\n\n\n\n
Driving and using machines<\/h2>\n\n\n\n
Memantine Accord contains lactose<\/h2>\n\n\n\n
How to take Memantine Accord<\/h2>\n\n\n\n
week 1<\/td> 5 mg tablet<\/td><\/tr> week 2<\/td> 10 mg tablet<\/td><\/tr> week 3<\/td> 15 mg tablet<\/td><\/tr> week 4and thereafter<\/td> 20 mg tablets once a day<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n If you take more Memantine Accord than you should<\/h2>\n\n\n\n
If you forget to take Memantine Accord<\/h2>\n\n\n\n
Possible side effects<\/h2>\n\n\n\n
How to store Memantine Accord<\/h2>\n\n\n\n
Contents of the pack and other information<\/h2>\n\n\n\n
Content declaration<\/h2>\n\n\n\n
What the medicine looks like and contents of the pack<\/h2>\n\n\n\n
Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n