{"id":17425,"date":"2022-01-12T08:14:35","date_gmt":"2022-01-12T08:14:35","guid":{"rendered":"https:\/\/zeepedia.com\/?p=17425"},"modified":"2022-01-13T07:48:51","modified_gmt":"2022-01-13T07:48:51","slug":"medrol","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/medrol\/","title":{"rendered":"Medrol &#8211; Methylprednisolone uses, dose and side effects"},"content":{"rendered":"\n<p>4 mg, 16 mg&nbsp;tablets<br>methylprednisolone<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Medrol is and what it is used for<\/h2>\n\n\n\n<p>Medrol, which is a cortisone preparation, has an inhibitory effect on\u00a0allergies\u00a0and\u00a0inflammation.<\/p>\n\n\n\n<p>Medrol is used to e.g.\u00a0treat inflammatory diseases such as rheumatism,\u00a0ulcerative colitis,\u00a0and\u00a0asthma\u00a0as well as in other conditions such as\u00a0certain blood changes and severe allergic conditions.<\/p>\n\n\n\n<p>Methylprednisolone contained in Medrol may also be approved for the treatment of other conditions not mentioned in this leaflet.\u00a0Ask your doctor, pharmacist, or another healthcare professional if you have any further questions, and always follow their instructions.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before you use Medrol<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not take Medrol<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to methylprednisolone or any of the other ingredients of this medicine (listed in section 6)<\/li><li>if you have a fungal infection that affects your entire body.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before taking Medrol<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you suffer from osteoporosis<\/li><li>if you suffer from any seizure disorder<\/li><li>if you suffer from&nbsp;glaucoma&nbsp;and herpes infection of the eye<\/li><li>if you suffer from&nbsp;stomach ulcers&nbsp;or other serious gastrointestinal problems<\/li><li>if you suffer from&nbsp;kidney failure<\/li><li>if you suffer from&nbsp;scleroderma&nbsp;(also called systemic sclerosis, an&nbsp;autoimmune&nbsp;disease)<\/li><li>if you suffer from&nbsp;adrenal&nbsp;tumor&nbsp;(&nbsp;pheochromocytoma&nbsp;)<\/li><li>if you suffer from certain mental disorders<\/li><li>if you suffer from&nbsp;diabetes<\/li><li>if you suffer from high&nbsp;blood pressure<\/li><li>if you suffer from heart disease<\/li><li>if you suffer from hypothyroidism<\/li><li>if you suffer from&nbsp;myasthenia gravis<\/li><li>if you have chickenpox or measles<\/li><li>if you have an&nbsp;infection&nbsp;, or get an&nbsp;infection&nbsp;while using Medrol<\/li><\/ul>\n\n\n\n<p>People treated with drugs such as Medrol can developmental disorders that can develop into thoughts of harming themselves or committing suicide.\u00a0If you ever have these problems or thoughts, contact your doctor immediately.\u00a0These symptoms can especially occur during or just after dose changes or during discontinuation of cortisone treatment.<\/p>\n\n\n\n<p>Contact a doctor if you experience blurred vision or other visual disturbances.<\/p>\n\n\n\n<p>Infection\u00a0can be exacerbated by treatment with\u00a0cortisone.<\/p>\n\n\n\n<p>If you are going to be vaccinated, you should tell them that you are being treated with Medrol.<\/p>\n\n\n\n<p>Medrol treatment may mean that&nbsp;allergy tests&nbsp;on the skin do not give reliable answers.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children and young people<\/h2>\n\n\n\n<p>Growth in children can be inhibited by long-term use.&nbsp;The doctor will regularly check the baby&#8217;s growth.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Medrol<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines, including medicines obtained without a prescription.<\/p>\n\n\n\n<p>Medrol can affect or be affected by other medicines such as:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>certain medicines for vomiting and nausea (aprepitant, fosaprepitant)<\/li><li>certain drugs used i.a.&nbsp;in connection with transplantation (cyclosporine, tacrolimus)<\/li><li>drugs used in heart disease (&nbsp;diltiazem&nbsp;)<\/li><li>certain&nbsp;antibiotics&nbsp;for bacterial infections (erythromycin, clarithromycin, telithromycin, triacetyloleandomycin, amphotericin B)<\/li><li>certain medicines for&nbsp;tuberculosis&nbsp;(rifampicin,&nbsp;isoniazid&nbsp;)<\/li><li>certain antifungal agents, which are taken in tablets or capsules (&nbsp;ketoconazole&nbsp;, itraconazole, voriconazole, posaconazole)<\/li><li>anticholinergic drugs (eg pancuronium and vecuronium)<\/li><li>certain medicines for&nbsp;HIV&nbsp;(ritonavir, cobicistat).&nbsp;Your doctor may want to monitor you closely if you are taking these medicines.&nbsp;<\/li><li>certain contraceptives (ethinyl estradiol, norethindrone)<\/li><li>certain medicines used in&nbsp;epilepsy&nbsp;(phenobarbital,&nbsp;phenytoin&nbsp;, carbamazepine)<\/li><li>herbal medicine containing&nbsp;St. John&#8217;s wort&nbsp;(used for depression)<\/li><li>drugs that affect&nbsp;coagulation&nbsp;(the ability of the blood to clot)<\/li><li>medicines used to treat fever and pain (&nbsp;acetylsalicylic acid&nbsp;)<\/li><li>anti-inflammatory drugs (&nbsp;NSAIDs&nbsp;, eg&nbsp;ibuprofen&nbsp;,&nbsp;diclofenac&nbsp;)<\/li><li>blood sugar lowering drugs (antidiabetic drugs)<\/li><li>anticholinesterases (used to treat&nbsp;myasthenia gravis&nbsp;)<\/li><li>certain anticancer medicines (cyclophosphamide, aminoglutethimide)<\/li><li>Potassium-lowering drugs (eg&nbsp;diuretics&nbsp;)<\/li><li>medicines containing xanthene<\/li><li>medicines for&nbsp;asthma&nbsp;(beta-2&nbsp;agonists&nbsp;).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Medrol with food, drink and alcohol<\/h2>\n\n\n\n<p>You should avoid a concomitant intake of grapefruit juice and Medrol as grapefruit juice can affect how Medrol works in your body.\u00a0Grapefruit juice inhibits liver function so that Medrol is not broken down properly.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, breastfeeding and fertility<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<\/p>\n\n\n\n<p><em>Pregnancy<\/em><\/p>\n\n\n\n<p>There is a risk that the fetus is affected.\u00a0In long-term treatment, low birth weight, withdrawal symptoms, and isolated cases of cataracts have been seen in infants.\u00a0Do not use Medrol during pregnancy except on certain\u00a0prescriptions\u00a0from the doctor.<\/p>\n\n\n\n<p><em>Breast-feeding<\/em><\/p>\n\n\n\n<p>There is a risk that a breastfed baby is affected, as small amounts of methylprednisolone pass into breast milk.\u00a0Do not use Medrol while breastfeeding except on certain\u00a0prescriptions\u00a0from the doctor.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Medrol usually has no or negligible influence on the ability to drive and use machines.\u00a0Side effects\u00a0such as dizziness, visual disturbances, and fatigue may occur after treatment with\u00a0cortisone.\u00a0If you get these\u00a0side effects, do not drive or use machines.<\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects.\u00a0Descriptions of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Medrol contains lactose and sucrose<\/h2>\n\n\n\n<p>If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to use Medrol<\/h2>\n\n\n\n<p>Always take this medicine exactly as your doctor has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p>Dose\u00a0one should be determined by a doctor who will tailor it individually for you.\u00a0It is very important to follow the\u00a0dosage\u00a0prescribed by your doctor.\u00a0Medrol can be dosed very differently for different patients.\u00a0Often a high\u00a0dose\u00a0is given on the\u00a0first day,\u00a0dose\u00a0one is then gradually reduced.\u00a0During long-term treatment, your doctor may sometimes recommend that you take the tablets every other day.\u00a0The way Medrol is dosed can be crucial to the outcome of treatment.<\/p>\n\n\n\n<p>Medrol treatment must not be stopped without consulting your doctor.\u00a0Also, consult your doctor if fever or other symptoms occur during treatment.<\/p>\n\n\n\n<p>The notch is not intended for splitting the tablet.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n<p>During cortisone treatment, several\u00a0side effects\u00a0can occur, among other things as a result of the body&#8217;s cortisone production being suppressed.\u00a0Different dosing schedules can reduce the risk of\u00a0side effects, especially with long-term use.<\/p>\n\n\n\n<p><strong>Stop taking Medrol and contact a doctor immediately if you get any of the following symptoms:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Swelling of the face, tongue or throat;&nbsp;difficulty swallowing;&nbsp;hives&nbsp;and difficulty breathing (&nbsp;angioedema&nbsp;or&nbsp;anaphylactic reaction&nbsp;).<\/li><\/ul>\n\n\n\n<p><strong>Common&nbsp;<\/strong><strong>(may&nbsp;<\/strong><strong>affect&nbsp;<\/strong><strong>up to&nbsp;<\/strong><strong>1 in&nbsp;<\/strong><strong>10 people)<\/strong><\/p>\n\n\n\n<p>Decreased defense of infection, lower levels of certain\u00a0hormones, a side effect complex that can occur with long-term use manifests itself in the form of fat accumulation on the face and between the shoulder blades, growth retardation in children, local loss of muscle and skin with deterioration of wound healing, osteoporosis, worsening of\u00a0diabetes, low potassium level which can cause fatigue, high sodium level with fluid retention as a result.<\/p>\n\n\n\n<p><strong>Uncommon&nbsp;<\/strong><strong>(may&nbsp;<\/strong><strong>affect&nbsp;<\/strong><strong>up to&nbsp;<\/strong><strong>1 in 100&nbsp;<\/strong><strong>people)<\/strong><\/p>\n\n\n\n<p>Activation of mental illness, high\u00a0blood pressure, cataracts,\u00a0glaucoma\u00a0(increased pressure in the eye).<\/p>\n\n\n\n<p><strong>Rare&nbsp;<\/strong><strong>(may&nbsp;<\/strong><strong>affect&nbsp;<\/strong><strong>up to&nbsp;<\/strong><strong>1 in 1,000&nbsp;<\/strong><strong>people)<\/strong><\/p>\n\n\n\n<p>Allergic reactions\u00a0increased pressure in the skull,\u00a0stomach ulcers, allergic skin reactions,\u00a0hypersensitivity reaction, bone tissue damage, tendon rupture (especially the hamstrings).<\/p>\n\n\n\n<p><strong>Has been reported (occurs in&nbsp;<\/strong><strong>an&nbsp;<\/strong><strong>unknown number of&nbsp;<\/strong><strong>users)<\/strong><\/p>\n\n\n\n<p>Infection&nbsp;, increased&nbsp;white blood cell count&nbsp;(&nbsp;leukocytosis&nbsp;), hypersensitivity to drugs, severe&nbsp;allergic reaction&nbsp;, pheochromocyte-related crisis (symptoms such as attacking headache, palpitations, sweating and pallor), withdrawal symptoms on tap, elevated&nbsp;pHin the blood, in the blood, lipid disorders, accumulation of adipose tissue in isolated places on the body, emotional symptoms (including depression, feelings of happiness, rapid mood swings, drug addiction, suicidal thoughts), psychotic disorders (including mania, delusions, hallucinations, exacerbation, hallucinations and exacerbation) , anxiety, mood swings, abnormal behavior, sleep problems, irritability, cramps, memory problems, intellectual disorder, dizziness, headache, blurred vision, protruding eyeballs, blurred vision,&nbsp;heart failure&nbsp;(in sensitive patients), increased tendency to get blood clots, hiccups,&nbsp;inflammation&nbsp;in the intestines,in the pancreas, esophagitis, bloated stomach, abdominal pain, nausea, increase in liver enzymes, short-term and limited swelling (mainly in the skin) which is often caused by allergies, increased male body hair in women, bleeding in the skin, bruising, skin wasting, reddening of the skin, redness stretch marks (blue-red streaks on the chest and abdomen),&nbsp;itching&nbsp;,&nbsp;hives&nbsp;,&nbsp;acne&nbsp;, muscle disease, muscle weakness,&nbsp;fracture&nbsp;without previous trauma, irregular menstruation, swollen legs and feet, general malaise, increased appetite (which may result in weight gain), increased&nbsp;calcium&nbsp;in urine, increased level of&nbsp;urea&nbsp;in the blood (blood test value) and decreased reaction to skin tests.&nbsp;<\/p>\n\n\n\n<p>Since Medrol is used in conditions of illness which in many cases are considered serious, it is important not to interrupt treatment, e.g.\u00a0due to\u00a0side effects, without first consulting a doctor.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to store Medrol<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the carton after EXP.\u00a0day.\u00a0The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents of the pack and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<p><em>4 mg tablet<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is methylprednisolone.&nbsp;One tablet contains 4 mg of methylprednisolone.<\/li><li>The other ingredients are&nbsp;lactose monohydrate&nbsp;(80 mg), calcium stearate, sucrose (1.5 mg) and corn starch.<\/li><\/ul>\n\n\n\n<p><em>16 mg tablet<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is methylprednisolone One tablet contains 16 mg methylprednisolone.<\/li><li>The other ingredients are&nbsp;lactose monohydrate&nbsp;(159 mg), calcium stearate, sucrose (2.80 mg), liquid paraffin and corn starch.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and contents of the pack<\/h2>\n\n\n\n<p>4 mg: Oval, white cross-scored tablet, debossed with \u201cMedrol 4\u201d on one side.&nbsp;The notch is not intended for splitting the tablet.<\/p>\n\n\n\n<p>16 mg: Oval, white cross-scored tablet, debossed with \u201cMedrol 16\u201d on one side.&nbsp;The notch is not intended for splitting the tablet.<\/p>\n\n\n\n<p>Tablets 4 mg: Glass jar 98 and 100 tablets<\/p>\n\n\n\n<p>Tablets 16 mg: Glass jar 49 and 50 tablets<\/p>\n\n\n\n<p>Tablets 4 mg: Plastic jar with child-resistant lid 100 tablets<\/p>\n\n\n\n<p>Tablets 16 mg: Plastic jar with child-resistant lid 50 tablets<\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p>Pfizer AB<\/p>\n\n\n\n<p>191 90 Sollentuna<\/p>\n\n\n\n<p>Tel: 08 &#8211; 550 520 00<\/p>\n\n\n\n<p>Email: eumedinfo@pfizer.com<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Medrol is used to e.g. treat inflammatory diseases such as rheumatism, ulcerative colitis and asthma as well as in other conditions such as certain blood changes and severe allergic conditions.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,15580],"tags":[16847,16841,16842,16846,16845,5910,5912,16840,16843,5911,16844,16839],"class_list":["post-17425","post","type-post","status-publish","format-standard","hentry","category-medicines","category-m","tag-benefits-of-medrol","tag-benefits-of-methylprednisolone","tag-medrol","tag-medrol-side-effects","tag-medrol-tablet","tag-methylprednisolone","tag-methylprednisolone-side-effects","tag-methylprednisolone-tablet","tag-what-is-medrol","tag-what-is-methylprednisolone","tag-what-medrol-is-used-for","tag-what-methylprednisolone-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/17425","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=17425"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/17425\/revisions"}],"predecessor-version":[{"id":17452,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/17425\/revisions\/17452"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=17425"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=17425"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=17425"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}