{"id":17419,"date":"2022-01-12T07:58:52","date_gmt":"2022-01-12T07:58:52","guid":{"rendered":"https:\/\/zeepedia.com\/?p=17419"},"modified":"2023-01-19T06:35:33","modified_gmt":"2023-01-19T06:35:33","slug":"medanef","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/medanef\/","title":{"rendered":"Medanef &#8211; Methylphenidate Hydrochloride Uses, Dose, And Side Effects"},"content":{"rendered":"\n<p><strong>Medanef 5 mg, 10 mg, and 20 mg\u00a0tablets of methylphenidate hydrochloride<\/strong><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Medanef Is And What Medanef Used For<\/h2>\n\n\n\n<p>Medanef contains the active substance methylphenidate hydrochloride.<\/p>\n\n\n\n<p><strong>What is it used for<\/strong><\/p>\n\n\n\n<p><strong>Medanef a&nbsp;nv\u00e4nds for&nbsp;treating &#8216;Attention Deficit Hyperactivity Disorders &#8220;(&nbsp;ADHD&nbsp;).<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>It is used in children and adolescents aged 6 to 18 years.<\/li><li>It is used only after other drug-free treatment methods have been tried, such as talk therapy and behavioral therapy.<br>Medanef is not used to treat\u00a0ADHD\u00a0in children under 6 years of age or adults.\u00a0The safety and benefits of treatment have not been established in this patient population.<\/li><\/ul>\n\n\n\n<p><strong>How it works<\/strong><\/p>\n\n\n\n<p>Medanef improves the activity in certain areas of the brain which are underactive.\u00a0The drug can help improve attention (to retain attention), the ability to concentrate and reduce impulsive behavior. The drug is given as part of a treatment program, which usually includes the following:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Psychological\u00a0therapy<\/li><li>Training<\/li><li>Social\u00a0therapy<br><strong>Medanef should only be initiated and used under the supervision of a doctor who specializes in behavioral problems in children and adolescents.\u00a0<\/strong>\u00a0Although there is no cure for\u00a0ADHD, it can be managed with the help of a treatment program.<\/li><\/ul>\n\n\n\n<p><strong>About&nbsp;ADHD<\/strong><\/p>\n\n\n\n<p>Children and adolescents with\u00a0ADHD\u00a0may experience the following:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Difficulty sitting still<\/li><li>Difficulty concentrating<br>It&#8217;s not their fault that they can not do these things.<br>Many children and young people are struggling to cope with these things.\u00a0In people with\u00a0ADHD, problems in everyday life can occur.\u00a0Children and adolescents with\u00a0ADHD\u00a0may have difficulty learning and doing homework.\u00a0They have difficulty behaving well at home, at school, or elsewhere.<br>ADHD\u00a0does not affect the intelligence of a child or adolescent.<br>Methylphenidate hydrochloride contained in Medanef may also be approved for treating other conditions not mentioned in this product information.\u00a0Ask your doctor, pharmacist, or another healthcare professional if you have further questions, and always follow their instructions.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What You Need To Know Before You Or Your Child Use Medanef<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do Not Use Medanef If You Or Your Child<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Is allergic to methylphenidate or any of the other ingredients of this medicine (listed in section 6)<\/li><li>Have problems with the thyroid gland<\/li><li>Has increased pressure in the eye (\u00a0glaucoma\u00a0)<\/li><li>Has a\u00a0tumor\u00a0in the adrenal gland (\u00a0pheochromocytoma\u00a0)<\/li><li>Have an eating disorder that makes you not feel hungry or not want to eat, such as &#8220;anorexia nervosa.&#8221;<\/li><li>Have very high\u00a0blood pressure\u00a0or narrowing of the blood vessels, which can cause pain in the arms and legs<\/li><li>Have or have had heart problems, such as heart attack, irregular heartbeat, chest pain and discomfort,\u00a0heart failure, heart disease, or have a congenital heart defect<\/li><li>Have had problems with the blood vessels in the brain, such as a\u00a0stroke, dilated or weakened blood vessels (\u00a0aneurysm\u00a0), narrowing or blockage in the blood vessels, or\u00a0inflammation\u00a0of the blood vessels (\u00a0vasculitis\u00a0)<\/li><li>Currently taking or have taken antidepressants called\u00a0monoamine oxidase inhibitors\u00a0(\u00a0MAOIs\u00a0)\u00a0for the past 14 days; see section \u201cOther medicines and Medanef.\u201d<\/li><li>Have or have had mental problems such as:<ul><li>Psychopathic or\u00a0borderline\u00a0personality disorder<\/li><li>Abnormal thoughts or visions or schizophrenia<\/li><\/ul><\/li><li>Signs of serious mental problems such:<ul><li>Suicidal thoughts<\/li><li>Severe depression is when you feel very sad, useless, or hopeless.<\/li><li>Mania, where you feel joyful, overactive, and uninhibited<\/li><\/ul><\/li><\/ul>\n\n\n\n<p>Do not take Medanef if any of the above apply to you or your baby.\u00a0If unsure, talk to your doctor or pharmacist before taking Medanef.\u00a0This is because methylphenidate can aggravate these problems.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings And Cautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before you or your child take Medanef if you or your child:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Have liver or kidney problems<\/li><li>Have had seizures (seizures,\u00a0epilepsy\u00a0) or abnormal findings when measuring brain activity (\u00a0EEC\u00a0)<\/li><li>Is a girl and has started menstruating (see section &#8220;Pregnancy, breast-feeding and fertility&#8221;)<\/li><li>Have you ever abused or been addicted to alcohol, prescription drugs, or drugs<\/li><li>Have difficult-to-control, repeated twitches in any part of the body or repeat sounds and words (\u00a0tics\u00a0)<\/li><li>Have high\u00a0blood pressure<\/li><li>Have heart problems not mentioned in the section &#8220;Do not use Medanef if you or your child.&#8221;<\/li><li>Have mental health problems not mentioned in the section \u201cDo not use Medanef if you or your child.\u201d<\/li><\/ul>\n\n\n\n<p>Other mental health problems include:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Mood swings (from being manic to becoming depressed, so-called\u00a0bipolar disorder\u00a0)<\/li><li>Incipient aggression or hostility, or if aggression worsens<\/li><li>To believe in things that are not real (delusions)<\/li><li>To feel unusually suspicious (\u00a0paranoid\u00a0)<\/li><li>To feel anxious, anxious or tense<\/li><li>To feel depressed or to have feelings of guilt<\/li><\/ul>\n\n\n\n<p>If any of the above applies to you or your child, tell your doctor or pharmacist before starting treatment.&nbsp;This is because methylphenidate can aggravate these problems.&nbsp;The doctor will want to follow up on how the medicine affects you or your child.<\/p>\n\n\n\n<p><strong>Checks that your doctor will do before you or your child start taking Medanef<\/strong><\/p>\n\n\n\n<p>These checks determine if Medanef is suitable for you or your child.\u00a0Your doctor will talk to you about the following:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>If you or your child are taking other medicines<\/li><li>If there have been any sudden unexplained deaths in the family<\/li><li>Presence of other possible medical problems (such as heart problems) in you, your child, or other people in your family<\/li><li>How you or your child feel, e.g.\u00a0if you are elated or depressed, have strange thoughts, or if you or your child have had any such feelings in the past<\/li><li>If there have been &#8220;tics&#8221; within the family (difficult-to-control repeated twitches in any part of the body or repetition of sounds and words)<\/li><li>If you or your child or other family member has or has had a problem related to mental health or behavioral disorder.\u00a0The doctor will discuss whether you or your child are at risk of mood swings (from being manic to becoming depressed, so-called &#8220;bipolar disorder&#8221;).\u00a0Your or your child&#8217;s previous mental health will be checked.\u00a0It will also be checked if there has been suicide,\u00a0bipolar disorder,\u00a0or depression\u00a0in your family.<\/li><\/ul>\n\n\n\n<p>You must provide as much information as you can.\u00a0This will help your doctor decide if Medanef is suitable for you or your child.\u00a0Your doctor may decide that more medical tests are needed before you or your child can start taking this medicine.<\/p>\n\n\n\n<p><strong>During treatment<\/strong><\/p>\n\n\n\n<p>If you or your child take this medicine for more than 12 months, your doctor may want to monitor your heart function, height, weight, appetite, or mental health.\u00a0Your doctor may also ask you or your child to stop taking Medanef to see if treatment is still needed.<\/p>\n\n\n\n<p>Tell your doctor if you or your child get any of the following:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Uncontrolled speech or body movements<\/li><li>Any changes or deterioration of your mood or behavior<\/li><li>Breathing difficulties<\/li><li>Respiratory distress<\/li><li>Chest pain or palpitations (rapid heartbeat that feels throbbing in the chest).<\/li><\/ul>\n\n\n\n<p>Based on this, your doctor may decide to discontinue treatment.\u00a0Your doctor may check this at each dose change, every six months, or every visit.<\/p>\n\n\n\n<p>During treatment, boys and adolescents may unexpectedly experience prolonged\u00a0erections.\u00a0It can be a painful condition that can occur at any time.\u00a0You must contact your doctor immediately if an\u00a0erection\u00a0lasts more than 2 hours, especially if it is painful.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other Medicines And Medanef<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you or your child are taking, have recently taken, or might take any other medicines.<\/p>\n\n\n\n<p>Do not take Medanef if you or your child:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Take a medicine called\u00a0monoamine oxidase inhibitor\u00a0(\u00a0MAOI\u00a0) for depression, or take an\u00a0MAOI\u00a0for the last 14 days.\u00a0Taking\u00a0MAOIs\u00a0together with methylphenidate can lead to a sudden increase in\u00a0blood pressure.<\/li><\/ul>\n\n\n\n<p>If you or your child take other medicines, methylphenidate may affect how well they work or cause\u00a0side effects.\u00a0If you or your child are taking any of the following medicines, you must consult your doctor or pharmacist before taking methylphenidate:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Other\u00a0antidepressants,\u00a0such as\u00a0tricyclic antidepressants\u00a0(eg, amitriptyline, clomipramine) or selective serotonin reuptake inhibitors (SSRIs eg\u00a0citalopram,\u00a0fluoxetine\u00a0)<\/li><li>Drugs for severe mental problems, amisulpride,\u00a0risperidone, lithium,\u00a0haloperidol<\/li><li>DOPA\u00a0&#8211; a drug for\u00a0Parkinson&#8217;s disease<\/li><li>Drugs against\u00a0epilepsy\u00a0(such as phenobarbital, phenytoin, and primidone)<\/li><li>Medicines used to lower or raise\u00a0blood pressure\u00a0(eg, clonidine)<\/li><li>Certain preparations for coughs or colds may contain substances that affect\u00a0blood pressure.\u00a0It is important to consult the pharmacy staff before buying any such product.<\/li><li>Drugs that thin the blood to prevent blood clots.\u00a0(e.g., coumarin or\u00a0warfarin\u00a0).<br>If you are unsure if any of the medicines you and your child are taking are listed above, ask your doctor or pharmacist for advice before taking Medanef.<\/li><\/ul>\n\n\n\n<p><strong>Operation<\/strong><\/p>\n\n\n\n<p>Tell your doctor if you or your child will undergo surgery.&nbsp;Medanef should not be taken on the day of surgery if a special type of anesthetic\/anesthetic is used.&nbsp;This is because there is a risk of sudden high&nbsp;blood pressure&nbsp;during surgery.<\/p>\n\n\n\n<p><strong>Drug tests<\/strong><\/p>\n\n\n\n<p>This drug can give positive results in drug abuse tests.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Medanef With Food And Alcohol<\/h2>\n\n\n\n<p>Taking Medanef with food may relieve abdominal pain, nausea, or vomiting.<\/p>\n\n\n\n<p>Do not drink alcohol while using this medicine.&nbsp;Alcohol can aggravate the&nbsp;side effects of the drug.&nbsp;Keep in mind that some dishes and medicines may contain alcohol.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, Breastfeeding, And Fertility<\/h2>\n\n\n\n<p>Available data do not indicate an increased risk of malformations overall.&nbsp;However, it can not be ruled out that there is a small increase in the risk of heart defects when used during the first three months of pregnancy.&nbsp;Your doctor can provide more information about this risk.&nbsp;Methylphenidate is transferred to breast milk.<\/p>\n\n\n\n<p>Talk to your doctor or pharmacist if you or your daughter:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Is sexually active.\u00a0The doctor will discuss contraception.<\/li><li>Is pregnant or suspects pregnancy.\u00a0Your doctor will decide if Medanef should be used.<\/li><li>Breastfeeding or planning to breastfeed.\u00a0Methylphenidate may be transferred to breast milk.\u00a0Therefore, your doctor will decide if breastfeeding can be done during treatment with Medanef. If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Driving And Using Machines<\/h2>\n\n\n\n<p>You may feel dizzy, have trouble focusing your eyes, or have blurred vision when using Medanef.\u00a0If this happens, driving, using machines, cycling, riding, or climbing trees can be dangerous.<\/p>\n\n\n\n<p>You are responsible for assessing whether you can drive a motor vehicle or perform work requiring sharpened attention.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects or\u00a0side effects.\u00a0Descriptions of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How To Use Medanef<\/h2>\n\n\n\n<p>Your doctor will do some tests before you or your child start treatment when the\u00a0dose is\u00a0changed and during the treatment at least every 6 months or at each doctor&#8217;s visit.\u00a0This ensures that the treatment is safe and beneficial for you or your child.\u00a0These surveys will include the following:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Measurement of\u00a0blood pressure\u00a0and\u00a0heart rate\u00a0recorded in a table<\/li><li>Measurement of height and weight, control of appetite recorded in a table<\/li><li>Assessment of mental symptoms.\u00a0(see section 2, &#8220;Warnings and Precautions&#8221;)<\/li><\/ul>\n\n\n\n<p><strong>How much to take<\/strong><\/p>\n\n\n\n<p>You or your child should always take this medicine according to the doctor&#8217;s or pharmacist&#8217;s instructions.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>The doctor usually starts treatment with a low\u00a0dose\u00a0that gradually increases as needed.<\/li><li>The highest recommended daily\u00a0dose\u00a0is 60 mg.<\/li><li>You or your child should take Medanef once or twice daily (for breakfast and lunch) with a glass of water.<\/li><li>The notch on the tablet is intended for splitting the tablet if you have difficulty swallowing the whole tablet (only 10 mg and 20 mg)<\/li><\/ul>\n\n\n\n<p><strong>If you or your child does not feel better after 1 month of treatment<\/strong><\/p>\n\n\n\n<p>Tell your doctor if you or your child does not feel better.&nbsp;Your doctor may decide to use another treatment.<\/p>\n\n\n\n<p><strong>Long-term treatment<\/strong><\/p>\n\n\n\n<p>Medanef does not need to be taken forever.&nbsp;If you have been taking Medanef for more than a year, your doctor will stop the treatment for a short time.&nbsp;This can be done during a school holiday.&nbsp;This is to check if the medicine is still needed.<\/p>\n\n\n\n<p><strong>Not using Medanef properly.<\/strong><\/p>\n\n\n\n<p>If Medanef is not used properly, it can lead to abnormal behavior.&nbsp;It can also mean that you \/ your child may become addicted to the drug.&nbsp;Tell your doctor if you \/ your child has ever abused or been addicted to alcohol, drugs, or narcotics.<\/p>\n\n\n\n<p>This medicine has only been prescribed for you \/ your child.\u00a0Do not give it to others even if they have similar symptoms.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Possible Medanef Side Effects<\/h2>\n\n\n\n<p>This medicine can cause side effects like all medicines, although not everybody gets them. Although some people experience\u00a0side effects, most find that methylphenidate helps them.\u00a0Your doctor will talk to you about these\u00a0side effects.<\/p>\n\n\n\n<p><strong>Some&nbsp;side effects&nbsp;can be very serious.&nbsp;If you or your child experience any of the&nbsp;side effects&nbsp;listed below, contact your healthcare provider immediately:<\/strong><\/p>\n\n\n\n<p><strong>Common (may affect up to 1 in 10 people)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Irregular heartbeat (\u00a0arrhythmia\u00a0) or throbbing heartbeat (palpitations)<\/li><li>Changes in\u00a0blood pressure\u00a0or heart rate (usually an increase)<\/li><\/ul>\n\n\n\n<p><strong>Uncommon (may affect up to 1 in 100 people)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Suicidal thoughts or feelings<\/li><li>Signs of\u00a0allergic reaction\u00a0such as rash,\u00a0itching,\u00a0or\u00a0hives\u00a0on the skin, swelling of the face, lips, tongue, or other body parts, shortness of breath, wheezing, or difficulty breathing<\/li><\/ul>\n\n\n\n<p><strong>Rare (may affect up to 1 in 1,000 people)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Heavy or pressing sensation over the chest with chest pain and shortness of breath during physical activity (this may be a sign of angina)<\/li><\/ul>\n\n\n\n<p><strong>Very rare (may affect up to 1 in 10,000 people&nbsp;<\/strong>&nbsp;<strong>)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Sudden chest pain that can spread to the neck and arm with shortness of breath and <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/cold\/\">cold<\/a> sweats. It may be a sign of a heart attack.<\/li><li>Sudden death<\/li><li>Suicide attempt (including completed suicide)<\/li><li>Seizures<\/li><li>Uncontrollable muscle cramps that affect the eyes, head, neck, body, and nervous system.\u00a0Due to a temporary lack of blood supply to the brain.<\/li><li>Sudden collapse, numbness or weakness in the arms and legs, dizziness or confusion, visual disturbances, difficulty swallowing, slurred speech, confusion, or loss of speech.\u00a0These can be signs of a\u00a0stroke\u00a0or mini-stroke\u00a0caused by a blockage or bleeding that affects the blood supply to a part of the brain.<\/li><li>Decreased number of\u00a0blood cells\u00a0(red and\u00a0white blood cells\u00a0and\u00a0platelets\u00a0), which can make you more susceptible to infections and make you bleed more easily or get bruises<\/li><li>Yellowing of the skin and eyes, dark urine, fatigue, fever, malaise, weakness, drowsiness, and abdominal pain.\u00a0These can be signs of serious liver problems.<\/li><li>Forgetfulness, poor judgment, fragrant breath, sleep disturbances, worsening hand movements, or tremors in hands and arms.\u00a0These are signs of brain problems caused by the liver not working.<\/li><li>A sudden increase in body temperature, very high\u00a0blood pressure,\u00a0and severe seizures (Neuroleptic malignant syndrome).\u00a0This\u00a0side effect\u00a0may not be\u00a0caused by methylphenidate or other medicines that may have been taken in combination with methylphenidate.<br>No known frequency (can not be calculated from the available data)<\/li><li>A decrease in the number of other blood cells, such as\u00a0red blood cells\u00a0or\u00a0platelets\u00a0which may cause fatigue, shortness of breath, pale skin, or cause unexplained bruising or bleeding for longer than normal<\/li><\/ul>\n\n\n\n<p><strong>Some&nbsp;side effects&nbsp;can be serious.&nbsp;If you or your child experience any of the&nbsp;side effects&nbsp;listed below, contact your healthcare provider immediately:<\/strong><\/p>\n\n\n\n<p><strong>Common (may affect up to 1 in 10 people)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Aggression, agitation, anxiety, depression, or behavior change<\/li><li>Weight loss<\/li><li>Slow growth.\u00a0You or your child, who is on long-term treatment, may grow more slowly compared to others of the same sex and age (growth retardation).<\/li><\/ul>\n\n\n\n<p><strong>Uncommon (may affect up to 1 in 100 people)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>See, feel, or hear things that are not real; signs of\u00a0psychosis<\/li><li>Uncontrolled speech, and uncontrolled body movements.\u00a0If you already have these symptoms or Tourette&#8217;s syndrome, they may worsen.<\/li><li>Mood swings and personality changes<\/li><\/ul>\n\n\n\n<p><strong>Rare (may affect up to 1 in 1,000 people)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>is elated, overactive, or uninhibited\u00a0<\/li><\/ul>\n\n\n\n<p><strong>No known frequency (can not be calculated from the available data)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Difficulty thinking or not thinking clearly<\/li><li>Long lasting\u00a0erection\u00a0you, sometimes painful, or number of\u00a0erections\u00a0you<\/li><\/ul>\n\n\n\n<p><strong>Other&nbsp;side effects&nbsp;are as follows:<\/strong><\/p>\n\n\n\n<p><strong>Very common (may affect more than 1 user in 10)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Headache<\/li><li>Nausea<\/li><li>Dry mouth<\/li><li>Nervousness<\/li><li>Insomnia<\/li><li>Decreased appetite<\/li><\/ul>\n\n\n\n<p><strong>Common (may affect up to 1 in 10 people)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><a href=\"https:\/\/zeepedia.com\/medical\/diseases\/joint-pain\/\">Joint pain<\/a><\/li><li>Fever<\/li><li>Cold hands and feet<\/li><li>Respiratory distress<\/li><li>Abnormal hair loss or thinning<\/li><li>Fatigue<\/li><li>Thirst<\/li><li>Abnormal fatigue or drowsiness<\/li><li>Loss of appetite<\/li><li><a href=\"https:\/\/zeepedia.com\/medical\/diseases\/cough-in-children\/\">Cough<\/a><\/li><li><a href=\"https:\/\/zeepedia.com\/medical\/diseases\/sore-throat\/\">Sore throat<\/a> or nose and throat irritation,\u00a0inflammation\u00a0of the airways<\/li><li>Toothache<\/li><li>Severe gnashing of teeth (bruxism)<\/li><li>High\u00a0blood pressure<\/li><li>Dizziness<\/li><li>Uncontrollable movements, hyperactivity<\/li><li>Shaking or trembling<\/li><li>Feeling stressed, irritated, restless<\/li><li>Feeling nervous<\/li><li>excessive sweating<\/li><li>Instability<\/li><li>Rapid mood swings<\/li><li>Panic attack<\/li><li>Difficulty sleeping<\/li><li>Decreased sexual desire<\/li><li>Indigestion<\/li><li>Stomach pain, diarrhea, stomach discomfort, and vomiting.\u00a0These usually occur at the beginning of treatment and can be reduced by taking medicine with food.<\/li><\/ul>\n\n\n\n<p><strong>Uncommon (may affect up to 1 in 100 people)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Constipation<\/li><li>Blood in the urine<\/li><li>Feeling of discomfort in the chest<\/li><li>Difficulty sitting or standing still<\/li><li>Blisters, flaking,\u00a0redness,\u00a0or flaking of the skin<\/li><li><a href=\"https:\/\/zeepedia.com\/medical\/diseases\/distinction-and-double-vision-in-adults\/\">Double vision<\/a> or blurred vision<\/li><li>Muscle tension, muscle aches, muscle twitching,<\/li><li>Chest pain<\/li><li>Elevated liver values \u200b\u200b(detected by a blood test)<\/li><li>Anger, tension, weeping, excessive attention to the environment,<\/li><\/ul>\n\n\n\n<p><strong>Rare (may affect up to 1 in 1,000 people)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Altered sex drive<\/li><li>Feel lost, confused about time, space, or personality (disoriented)<\/li><li>Dilated\u00a0pupil\u00a0er, difficult to focus the gaze<\/li><li>Swelling of the breasts in men<\/li><\/ul>\n\n\n\n<p><strong>Very rare (may affect up to 1 in 10,000 people)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Muscle cramps<\/li><li>Lack of feelings, interests, or commitment<\/li><li>Repetitive behaviors<\/li><li>Overfocusing<\/li><li>Changes in test results, such as an increase in alkaline phosphatase or\u00a0bilirubin, low\u00a0platelet count,\u00a0or abnormal\u00a0white blood cell levels<\/li><li>Loss of sensation in fingers and toes, tingling, and change in color (from white to blue, then red) on cold (Raynaud&#8217;s phenomenon).<\/li><\/ul>\n\n\n\n<p><strong>No known frequency (can not be calculated from the available data)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Migraine<\/li><li>Chest discomfort<\/li><li>Confusion<\/li><li>Very high fever<\/li><li>Slow or extra heartbeat<\/li><li>Depending on this medicine<\/li><li>Problems getting or maintaining\u00a0an erection<\/li><li>Inability to control urinary\u00a0incontinence\u00a0(\u00a0incontinence\u00a0)<\/li><li>Spasm\u00a0in the jaw muscles that makes it difficult to open the mouth (trismus)<\/li><li>Stuttering<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">How To Store Medanef<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Keep this medicine out of sight and reach of children.<\/li><li>Do not use this medicine after the expiry date stated on the can label and carton after EXP.\u00a0The expiration date is the last day of the specified month.<\/li><li>Do not store above 30 \u00b0 C.<\/li><\/ul>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.\u00a0Ask your pharmacist how to dispose of medicines that are no longer required.\u00a0These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents Of The Pack And Other Information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content Declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Medanef 5 mg tablets<ul><li>The active substance is methylphenidate hydrochloride.\u00a0Each tablet contains 5 mg of methylphenidate hydrochloride.<\/li><\/ul><\/li><li>Medanef 10 mg tablets<ul><li>The active substance is methylphenidate hydrochloride.\u00a0Each tablet contains 10 mg of methylphenidate hydrochloride.<\/li><\/ul><\/li><li>Medanef 20 mg tablets<ul><li> The active substance is methylphenidate hydrochloride.\u00a0Each tablet contains 20 mg of methylphenidate hydrochloride.<\/li><\/ul><\/li><li>Other ingredients are:<ul><li>Microcrystalline cellulose<\/li><li>Corn starch<\/li><li>Magnesium stearate<\/li><li>Calcium hydrogen phosphate dihydrate<\/li><\/ul><\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What The Medicine Looks Like And Contents Of The Pack<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Medanef, 5 mg tablets, are white, round, flat, marked with &#8220;RU&#8221; on one side and &#8220;5&#8221; on the other.<\/li><li>Medanef, 10 mg tablets, are white, round, flat tablet marked with &#8220;RU10&#8221; on one side.<\/li><li>Medanef, 20 mg tablets, are white, round, flat tablet marked with &#8220;RU20&#8221; on one side.<\/li><li>Medanef has the following blister packs available<ul><li>5 mg: 20, 30, 60, 100 tablets.<\/li><li>10 mg: 20, 30, 60, 100, 200 tablets.<\/li><li>20 mg: 20, 30, 60 tablets.<\/li><\/ul><\/li><li>Not all pack sizes may be marketed.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorisation Holder<\/h2>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>Laboratorios Rubi\u00f3, SA, Industria, 29, Pol.&nbsp;Ind.&nbsp;Comte de Sert, 08755 Castellbisbal, Barcelona<\/p>\n\n\n\n<p>Spain<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The medication Medanef is used to treat &#8220;attention deficit hyperactivity disorder&#8221; (ADHD).<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,15580],"tags":[16860,16849,16855,16858,16859,3956,3958,6661,16856,3957,16857,16848],"class_list":["post-17419","post","type-post","status-publish","format-standard","hentry","category-medicines","category-m","tag-benefits-of-medanef","tag-benefits-of-methylphenidate-hydrochloride","tag-medanef","tag-medanef-side-effects","tag-medanef-tablet","tag-methylphenidate-hydrochloride","tag-methylphenidate-hydrochloride-side-effects","tag-methylphenidate-hydrochloride-tablet","tag-what-is-medanef","tag-what-is-methylphenidate-hydrochloride","tag-what-medanef-is-used-for","tag-what-methylphenidate-hydrochloride-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/17419","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=17419"}],"version-history":[{"count":49,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/17419\/revisions"}],"predecessor-version":[{"id":45473,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/17419\/revisions\/45473"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=17419"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=17419"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=17419"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}