{"id":17416,"date":"2022-01-12T07:54:47","date_gmt":"2022-01-12T07:54:47","guid":{"rendered":"https:\/\/zeepedia.com\/?p=17416"},"modified":"2023-01-02T17:13:48","modified_gmt":"2023-01-02T17:13:48","slug":"mecastrin","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/mecastrin\/","title":{"rendered":"Mecastrin &#8211; Melatonin Uses, Dose And Side Effects"},"content":{"rendered":"\n<p><strong>Mecastrin 2 mg<\/strong>, <strong>Mecastrin 4 mg<\/strong> <strong>Prolonged Release Melatonin Tablet<\/strong><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Mecastrin Is And What It Is Used For<\/h2>\n\n\n\n<p>The active substance in <strong>Mecastrin melatonin<\/strong> belongs to a group of natural\u00a0hormones\u00a0produced by the body.<\/p>\n\n\n\n<p><strong>Mecastrin uses <\/strong>alone in the short-term treatment of primary insomnia (persistent difficulty falling asleep or continuing to sleep or poor sleep quality) in patients 55 years of age and older.\u00a0&#8220;Primary&#8221; means that insomnia has no known cause, such as any medical, mental, or environmental cause.<\/p>\n\n\n\n<p>Melatonin\u00a0contained in Mecastrin may also be approved for treating other conditions not mentioned in this product information.\u00a0Ask your doctor, pharmacist, or other healthcare professionals if you have further questions, and always follow their instructions.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What You Need To Know Before Taking Mecastrin<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do Not Take Mecastrin:<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>If you are allergic to<strong>\u00a0Mecastrin melatonin<\/strong> or any of the other ingredients of this medicine (listed in section 6).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings And Cautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before taking Mecastrin:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>If you have liver or kidney problems.\u00a0No studies on the use of Mecastrin in people with liver or kidney disease have been performed.\u00a0It would be best to talk to your doctor before taking Mecastrin, as its use is not recommended.<\/li><li>If your doctor has told you that you are intolerant to some sugars.<\/li><li>If you have been told you have an\u00a0autoimmune\u00a0disease (when the body is &#8220;attacked&#8221; by its immune system).\u00a0No studies on the use of Mecastrin in people with autoimmune diseases have been performed.\u00a0Therefore, you should talk to your doctor before taking Mecastrin, as its use is not recommended.<\/li><li>Mecastrin can make you feel drowsy.\u00a0You should be careful if drowsiness affects you, as it may impair your ability to perform tasks such as driving.<\/li><li>Smoking can have a worse effect on Mecastrin, as the ingredients in tobacco smoke can increase the breakdown of\u00a0melatonin\u00a0in the liver.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Children And Young People<\/h2>\n\n\n\n<p>Please do not give this medicine to children aged 0 to 18, as it has not been tested on children, and its effects are unknown.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other Medicines And Mecastrin<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.&nbsp;Such drugs may be:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Fluvoxamine (used to treat <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/depression\/\">depression<\/a> and obsessive-compulsive disorder), psoralen (used to treat skin conditions such as\u00a0psoriasis\u00a0), cimetidine (used to treat stomach problems such as\u00a0stomach ulcers\u00a0),\u00a0quinolones\u00a0and rifampicin (used to treat bacterial infections),\u00a0estrogen\u00a0er (used as a contraceptive or replacement therapy in case of hormone deficiency) and carbamazepine (used in the treatment of\u00a0epilepsy\u00a0).<\/li><li>Adrenergic agonists\/antagonists (such as certain types of medicines used to control\u00a0blood pressure\u00a0by constricting blood vessels, nasal decongestants, blood pressure lowering medicines), opiate antagonists\/antagonists (such as medicines used to treat drug addiction), prostaglandin inhibitors -steroidal anti-inflammatory drugs), antidepressants, tryptophan and alcohol.<\/li><li>Benzodiazepines\u00a0and\u00a0non-benzodiazepine-type\u00a0hypnotics\u00a0(drugs used to induce sleep such as zaleplon, zolpidem and\u00a0zopiclone\u00a0).<\/li><li>Thioridazine (used to treat <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/schizophrenia\/\">schizophrenia<\/a>) and imipramine (used to treat depression).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Mecastrin With Food, Drink And Alcohol<\/h2>\n\n\n\n<p>Take Mecastrin after meals.\u00a0Please do not drink alcohol before, during, or after taking Mecastrin, as it reduces the effect of Mecastrin.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy And Breastfeeding<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving And Using Machines<\/h2>\n\n\n\n<p>Mecastrin can make you drowsy.\u00a0If this happens, do not drive or use any machines.\u00a0If you always feel drowsy, you need to talk to your doctor.<\/p>\n\n\n\n<p>You are responsible for assessing whether you can drive a motor vehicle or perform work requiring sharpened attention.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects.\u00a0Descriptions of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Mecastrin Contains Lactose Monohydrate<\/h2>\n\n\n\n<p>Mecastrin contains\u00a0<a href=\"https:\/\/zeepedia.com\/medical\/diseases\/lactose-intolerance\/\">lactose<\/a> monohydrates.\u00a0If your doctor has told you that you have an intolerance to some sugars, contact your doctor before taking this medicine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3. How To Take Mecastrin<\/h2>\n\n\n\n<p><strong><span style=\"text-decoration: underline;\">Mecastrin uses<\/span><\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Always take this medicine exactly as your doctor or pharmacist has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/li><li>The recommended&nbsp;dose&nbsp;is one tablet (2 mg) taken once a day by mouth after a meal, 1-2 hours before bedtime.&nbsp;This&nbsp;dosage&nbsp;can be maintained for up to thirteen weeks.<\/li><li>You must swallow the tablet whole.&nbsp;You must not crush or split the tablets.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Possible Mecastrin Side Effects<\/h2>\n\n\n\n<p>This medicine can cause side effects like all medicines, although not everybody gets them.<\/p>\n\n\n\n<p>If you get any of the following serious\u00a0side effects,\u00a0stop taking medicine\u00a0<strong>immediately<\/strong>\u00a0and contact your doctor:<\/p>\n\n\n\n<p><strong>Uncommon<\/strong>&nbsp;(may affect up to 1 in 100 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Chest <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/brain-and-nerves\/pain\/\">pain<\/a><\/li><\/ul>\n\n\n\n<p><strong>Rare<\/strong>&nbsp;(may affect up to 1 in 1,000 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Unconsciousness or fainting<\/li><li>Severe chest pain due to angina<\/li><li>Palpitation<\/li><li>Depression<\/li><li>Impaired\u00a0visual acuity<\/li><li>Dimsyn<\/li><li>Confusion (disorientation)<\/li><li>Dizziness (a feeling of dizziness or that it &#8220;spins&#8221;)<\/li><li>Red blood cells\u00a0in the urine<\/li><li>Decreased number of\u00a0white blood cells\u00a0in the blood<\/li><li>Decreased\u00a0platelet count, which increases the risk of bleeding or bruising<\/li><li>Psoriasis<\/li><\/ul>\n\n\n\n<p>If you get any of the following non-serious&nbsp;side effects, contact your doctor and\/or see a doctor:<\/p>\n\n\n\n<p><strong>Uncommon<\/strong> <strong>Mecastrin side effects&nbsp;<\/strong>(may affect up to 1 in 100 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Irritability<\/li><li>Nervousness<\/li><li>Restlessness<\/li><li>Insomnia<\/li><li>Abnormal dreams<\/li><li>Nightmares<\/li><li>Anxiety<\/li><li>Migraines<\/li><li>Headaches<\/li><li>Lethargy\u00a0(lethargy, lack of energy)<\/li><li>Restlessness associated with increased activity<\/li><li>Dizziness<\/li><li>Drowsiness<\/li><li>High\u00a0blood pressure<\/li><li>Upper abdominal pain<\/li><li>Stomach upset<\/li><li>Sores in the mouth<\/li><li>Dry mouth<\/li><li>Nausea<\/li><li>Changes in the composition of the blood can cause yellowing of the skin and eyes<\/li><li>Dermatitis<\/li><li>Night sweats<\/li><li>Itching<\/li><li>Rash<\/li><li>Dry skin<\/li><li>Pain in the arms and legs<\/li><li>Menopausal symptoms<\/li><li>Feeling of weakness<\/li><li>Secretion of\u00a0glucose\u00a0in the urine<\/li><li>Too much\u00a0protein\u00a0in the urine<\/li><li>Abnormal liver function and weight gain<\/li><\/ul>\n\n\n\n<p><strong>Rare<\/strong>&nbsp;(may affect up to 1 in 1,000 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Shingles<\/li><li>High levels of fats in the blood<\/li><li>Low levels of\u00a0calcium\u00a0in the blood<\/li><li>Low levels of\u00a0sodium\u00a0in the blood<\/li><li>Changes in mood<\/li><li>Aggression<\/li><li>Anxiety<\/li><li>Crying mildness<\/li><li>Stress symptoms<\/li><li>Waking up early in the morning<\/li><li>Increased sexual drive<\/li><li>Depression<\/li><li>Memory loss<\/li><li>Attention deficit disorder<\/li><li>Attention deficit disorder<\/li><li>Restless legs syndrome<\/li><li>Poor sleep quality<\/li><li>Numbness and tingling sensation<\/li><li>Increased tear flow (watery eyes)<\/li><li>Dizziness (dizziness when getting up or sitting down)<\/li><li>Hot flashes<\/li><li>Acid regurgitation<\/li><li>Gastrointestinal upset<\/li><li>Blisters in the mouth, sores on the tongue<\/li><li>Stomach upset<\/li><li>Vomiting<\/li><li>Abnormal bowel sounds<\/li><li><a href=\"https:\/\/zeepedia.com\/medical\/diseases\/flatulence\/\">Flatulence<\/a><\/li><li>Excessive salivation<\/li><li>Bad breath<\/li><li>Abdominal discomfort<\/li><li>Stomach upset<\/li><li>Inflammation\u00a0of the gastric mucosa<\/li><li>Eczema<\/li><li>Skin rash<\/li><li>Inflammation of the hands on the hands<\/li><li>Itchy rash<\/li><li>Nail disorders<\/li><li>Joint inflammation<\/li><li>Muscle cramps<\/li><li>Neck pain<\/li><li>Nocturnal cramps<\/li><li>A prolonged\u00a0erection,\u00a0which can be painful<\/li><li>Inflammation\u00a0of the\u00a0prostate<\/li><li>Fatigue<\/li><li>Pain<\/li><li>Thirst<\/li><li>Large amounts of urine<\/li><li>Urination at night<\/li><li>Elevated liver worm saliva in the blood and abnormal laboratory tests<\/li><\/ul>\n\n\n\n<p><strong>Has been reported<\/strong>&nbsp;(occurs in an unknown number of users):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Hypersensitivity reaction<\/li><li>Swelling of the mouth or tongue<\/li><li>Swelling of the skin<\/li><li>Abnormal secretion of milk.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">How To Store Mecastrin<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Keep this medicine out of sight and reach of children.<\/li><li>Do not use this medicine after the expiry date stated on the carton after EXP.\u00a0The expiration date is the last day of the specified month.<\/li><li>Store in the original package.\u00a0Sensitive to light.<\/li><\/ul>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.\u00a0Ask your pharmacist how to dispose of medicines that are no longer required.\u00a0These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Contents Of The Pack And Other Information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content Declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is&nbsp;melatonin.&nbsp;One&nbsp;prolonged-release tablet&nbsp;contains 2 mg of&nbsp;melatonin.<\/li><li>The other ingredients are&nbsp;<ul><li>Lactose monohydrate<\/li><li>Calcium hydrogen phosphate dihydrate<\/li><li>Ammonio methacrylate copolymer<\/li><li>Talc<\/li><li>Colloidal&nbsp;anhydrous silica<\/li><li>Magnesium stearate<\/li><\/ul><\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What The Medicine Looks Like And Contents Of The Pack<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Mecastrin is a white to off-white, round, biconvex tablet.\u00a0Diameter: 8.00 \u00b1 0.20 mm.\u00a0Pack sizes: 7, 10, 20, 21, 24, 30, 36 or 100 tablets.<\/li><li>Not all pack sizes may be marketed.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder And Manufacturer<\/h2>\n\n\n\n<p>Orifarm Generics A \/ S<\/p>\n\n\n\n<p>Energivej 15<\/p>\n\n\n\n<p>5260 Odense S<\/p>\n\n\n\n<p>Denmark<\/p>\n\n\n\n<p><strong>Local representative<\/strong><\/p>\n\n\n\n<p>Orifarm Generics AB<\/p>\n\n\n\n<p>Box 56048<\/p>\n\n\n\n<p>102 17 Stockholm&nbsp;<\/p>\n\n\n\n<p>info@orifarm.com<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Mecastrin is the short-term treatment for immediate sleeplessness (continued difficulty falling, napping, or poor sleep quality) in patients 55 and older. <\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,15580],"tags":[16868,16862,16863,16867,16866,7147,7149,7150,16864,7148,16865,16861],"class_list":["post-17416","post","type-post","status-publish","format-standard","hentry","category-medicines","category-m","tag-benefits-of-mecastrin","tag-benefits-of-melatonin","tag-mecastrin","tag-mecastrin-side-effects","tag-mecastrin-tablet","tag-melatonin","tag-melatonin-side-effects","tag-melatonin-tablet","tag-what-is-mecastrin","tag-what-is-melatonin","tag-what-mecastrin-is-used-for","tag-what-melatonin-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/17416","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=17416"}],"version-history":[{"count":77,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/17416\/revisions"}],"predecessor-version":[{"id":42677,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/17416\/revisions\/42677"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=17416"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=17416"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=17416"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}