if you experience impaired vision or eye pain. This may be a symptom of fluid accumulation in the vascular layer of the eye (choroidal effusion) or an increase in pressure in the eye and may occur within a few hours to weeks after taking Marozid. This can lead to permanent vision loss if left untreated. If you have previously had a penicillin or sulfonamide allergy, you may be at higher risk of developing this.<\/li><\/ul>\n\n\n\nChildren and young people<\/h2>\n\n\n\n
Losartan potassium\/hydrochlorothiazide\u00a0should not be given to children and adolescents.<\/p>\n\n\n\n
Other medicines and Marozid<\/h2>\n\n\n\n
Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines, including medicines obtained without a prescription.<\/p>\n\n\n\n
Diuretics such as hydrochlorothiazide in Marozid may interact with other medicines.<\/p>\n\n\n\n
Medicines containing lithium should not be taken at the same time as Marozid without the close supervision of a doctor.<\/p>\n\n\n\n
Some preventative measures (ie blood tests) may be needed if you are taking potassium supplements, salt substitutes containing\u00a0potassium\u00a0or potassium-sparing agents, other\u00a0diuretics\u00a0(\u00a0diuretic\u00a0tablets), certain\u00a0laxatives, medicines to treat\u00a0gout, medicines to control the heart rhythm, or for\u00a0diabetes\u00a0(oral medicines or\u00a0insulin\u00a0).\u00a0It is also important that you tell your doctor if you are taking other antihypertensive drugs,\u00a0steroids, anticancer medicines, painkillers, antifungal medicines, or\u00a0arthritis\u00a0medicines, resins used for high\u00a0cholesterol such as cholestyramine, medicines that relax your muscles, sleeping pills, opioid medicines such as morphine, pressor amines such as\u00a0adrenaline\u00a0or other medicines from the same group, oral diabetes medicines or\u00a0insulin.<\/p>\n\n\n\n
Also, tell your doctor that you are taking Marozid if you will have an X-ray and will be given iodine contrast agents.<\/p>\n\n\n\n
Your doctor may need to change your\u00a0dose\u00a0and\/or take other precautions:<\/p>\n\n\n\n
If you are taking an ACE inhibitor or aliskiren (see also the information under the headings “Do not use Marozid” and “Warnings and precautions”).<\/p>\n\n\n\n
Marozide with food, drink and alcohol<\/h2>\n\n\n\n
You should not drink alcohol while taking this medicine: alcohol and Marozid may increase the effect of each other.<\/p>\n\n\n\n
Too much salt in the diet can counteract the effects of Marozid.<\/p>\n\n\n\n
Marozide can be taken with or without food.<\/p>\n\n\n\n
Pregnancy, breastfeeding and fertility<\/h2>\n\n\n\n
Pregnancy<\/em><\/p>\n\n\n\nIf you think you may be pregnant or become pregnant during treatment, consult your doctor.\u00a0Usually, your doctor will suggest that you stop taking Marozid before pregnancy or as soon as you know you are pregnant and instead recommend another medicine for you.\u00a0Marozide should not be used in early pregnancy and should not be used during the last 6 months of pregnancy as it may cause birth defects.<\/p>\n\n\n\n
Breast-feeding<\/em><\/p>\n\n\n\nTell your doctor if you are breastfeeding or planning to start breastfeeding.\u00a0Marozid is not recommended for breastfeeding and your doctor may choose another treatment for you if you want to breastfeed your baby.<\/p>\n\n\n\n
Use in elderly patients<\/strong><\/p>\n\n\n\nMarozide works just as well and is equally well tolerated by most older and younger adult patients. Most elderly patients need the same dose as younger patients.<\/p>\n\n\n\n
Driving and using machines<\/h2>\n\n\n\n
When starting treatment with this medicine, do not perform any tasks that may require special attention (such as driving or using dangerous machines) until you know how to tolerate the medicine.<\/p>\n\n\n\n
You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened vigilance.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects.\u00a0Descriptions of these effects and\u00a0side effects\u00a0can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n
Marozide contains Lactose<\/h2>\n\n\n\n
If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.<\/p>\n\n\n\n
How to use Marozid<\/h2>\n\n\n\n
Always use this medicine exactly as your doctor has told you.\u00a0Ask your doctor or pharmacist if you are unsure.\u00a0It is important to continue taking Marozid for as long as your doctor prescribes it to maintain even control of your\u00a0blood pressure.<\/p>\n\n\n\n
Adults<\/strong><\/p>\n\n\n\nMarozide 50 mg \/ 12.5 mg:<\/p>\n\n\n\n
Hypertension<\/em><\/p>\n\n\n\nThe usual dose is one tablet once a day. In some cases, your doctor may increase the dose to one to a maximum of two tablets once a day.<\/p>\n\n\n\n
Marozide 100 mg \/ 25 mg:<\/p>\n\n\n\n
High blood pressure<\/em><\/p>\n\n\n\nThe usual dose is one tablet once a day.<\/p>\n\n\n\n
Possible side effects<\/h2>\n\n\n\n
Like all medicines, this medicine can cause side effects, although not everybody gets them.<\/p>\n\n\n\n
If you experience any of the following symptoms, stop treatment with Marozid and contact a doctor or emergency department at the nearest hospital immediately.<\/p>\n\n\n\n
\u2022 Severe\u00a0allergic reaction\u00a0(rash,\u00a0itching, swelling of the face, lips, mouth, or throat which may cause difficulty swallowing or difficulty breathing)<\/p>\n\n\n\n
This is a serious but rare side effect that more than 1 in 10,000 users but less than 1 in 1000 users may get. You may need emergency medication or hospitalization.<\/p>\n\n\n\n
The following side effects have been reported:<\/p>\n\n\n\n
Common (may affect up to 1 in 10 users)<\/em><\/p>\n\n\n\n\u2022 cough, infection of the upper airways, nasal congestion, sinusitis, sinus problems<\/p>\n\n\n\n
\u2022 Diarrhea, abdominal pain, nausea, indigestion<\/p>\n\n\n\n
\u2022 Muscle pain or cramps, leg pain, back pain<\/p>\n\n\n\n
\u2022 Insomnia, headache, dizziness<\/p>\n\n\n\n
Weakness, fatigue, chest pain<\/p>\n\n\n\n
\u2022 Increased potassium levels (which may cause abnormal heart rhythm), decreased hemoglobin levels<\/p>\n\n\n\n
Uncommon (may affect up to 1 in 100 people)<\/em><\/p>\n\n\n\n\u2022\u00a0Anemia, red or brown spots on the skin (sometimes especially on the feet, legs, arms, and buttocks, with joint pain, swelling of hands and feet and stomach pain), bruising, reduction in\u00a0white blood cells, clotting, decreased number of\u00a0blood platelets<\/p>\n\n\n\n
\u2022 Loss of appetite, increased amount of\u00a0uric acid\u00a0or\u00a0gout, increased blood sugar, abnormal levels in the blood salt balance<\/p>\n\n\n\n
\u2022 Anxiety, nervousness, panic disorder (recurring panic attacks), confusion, depression, abnormal dreams, sleep disorders, drowsiness, impaired memory<\/p>\n\n\n\n
\u2022 Tingling and burning sensation or similar sensations, pain in arms and legs, tremors,\u00a0migraines, fainting<\/p>\n\n\n\n
\u2022 Blurred vision, burning or stinging sensation in the eyes, conjunctivitis, impaired vision, seeing things in yellow<\/p>\n\n\n\n
\u2022 Ringing, roaring, screaming, or clicking sounds in the ears<\/p>\n\n\n\n
\u2022 Low\u00a0blood pressure\u00a0which may be associated with altered body position (feeling of dizziness or weakness when you get up), chest pain, abnormal heart rhythm,\u00a0cerebrovascular\u00a0event (\u00a0TIA, “mini-stroke”), heart attack, palpitations<\/p>\n\n\n\n
\u2022 Inflammation of the blood vessels that often arises in connection with a rash or bruising<\/p>\n\n\n\n
Sore throat, shortness of breath,\u00a0inflammation\u00a0of the trachea,\u00a0pneumonia, water in the lungs (which causes difficulty breathing), nosebleeds, runny nose, nasal congestion<\/p>\n\n\n\n
\u2022 Constipation, gas, upset stomach, stomach cramps, vomiting,\u00a0dry mouth, salivary gland inflammation, toothache<\/p>\n\n\n\n
Jaundice (yellowing of the skin and eyes), inflammation of the pancreas<\/p>\n\n\n\n
\u2022 Hives,\u00a0itching, dermatitis, rash,\u00a0redness\u00a0of the skin, photosensitivity, dry skin,\u00a0redness, sweating, hair loss<\/p>\n\n\n\n
\u2022 Pain in the arms, shoulders, hips, knees or other joints, joint swelling, stiffness, muscle weakness<\/p>\n\n\n\n
\u2022 Often urinates even at night, abnormal kidney function including kidney inflammation, urinary tract infection, sugar in the urine<\/p>\n\n\n\n
\u2022 Decreased sexual desire, impotence<\/p>\n\n\n\n
\u2022 Swelling of the face, local swelling ( edema ), fever<\/p>\n\n\n\n
Rare (may affect up to 1 in 1,000 people)<\/em><\/p>\n\n\n\n\u2022 Hepatitis ( inflammation of the liver), abnormal liver function tests<\/p>\n\n\n\n
Has been reported (occurs in an unknown number of users)<\/em><\/p>\n\n\n\n\u2022 Flu-like symptoms<\/p>\n\n\n\n
\u2022 Unexplained muscle aches with dark (tea-colored) urine ( rhabdomyolysis )<\/p>\n\n\n\n
\u2022 Low levels of sodium in the blood ( hyponatremia )<\/p>\n\n\n\n
\u2022 General feeling of illness<\/p>\n\n\n\n
\u2022 Skin and lip cancer (Non- melanoma skin cancer)<\/p>\n\n\n\n
\u2022 Decreased vision or pain in the eyes due to high pressure (possible signs of fluid accumulation in the vascular layer (choroidal effusion) or acute narrow-angle glaucoma )<\/p>\n\n\n\n
How to store Marozid<\/h2>\n\n\n\n
Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n
Do not use this medicine after the expiry date which is stated on the carton after EXP. The expiration date is the last day of the specified month.<\/p>\n\n\n\n
Do not store above 30 \u00b0 C.<\/p>\n\n\n\n
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.<\/p>\n\n\n\n
Contents of the pack and other information<\/h2>\n\n\n\nContent declaration<\/h2>\n\n\n\n
– The active substances are losartan potassium and\u00a0hydrochlorothiazide.<\/p>\n\n\n\n
Marozide 50 mg \/ 12.5 mg: Each tablet contains 50 mg losartan potassium and 12.5 mg hydrochlorothiazide .<\/p>\n\n\n\n
Marozide 100 mg \/ 25 mg: Each tablet contains 100 mg losartan potassium and 25 mg hydrochlorothiazide .<\/p>\n\n\n\n
– The other ingredients are:<\/em><\/strong><\/p>\n\n\n\n– Tablet core: Microcrystalline cellulose (E460a),\u00a0lactose monohydrate, pregelatinized\u00a0starch\u00a0(maize), and magnesium stearate (E572).<\/p>\n\n\n\n
– Film coating: Hydroxypropylcellulose, hypromellose, titanium dioxide (E171), and yellow iron oxide (E172).<\/p>\n\n\n\n
What the medicine looks like and contents of the pack<\/h2>\n\n\n\n
Marozide 50 mg \/ 12.5 mg:<\/em><\/p>\n\n\n\nMarozid 50 mg \/ 12.5 mg are round, yellow film-coated tablets.<\/p>\n\n\n\n
The tablets are available in pack sizes of 7, 28, 50, 56, 50×1 (single dose), 98 and 100 (hospital pack) film-coated tablets.<\/p>\n\n\n\n
Marozide 100 mg \/ 25 mg:<\/em><\/p>\n\n\n\nMarozid 100 mg \/ 25 mg are round, yellow film-coated tablets.<\/p>\n\n\n\n
The tablets are available in pack sizes of 7, 28, 30, 50, 56, 90, 98 and 100 (hospital pack) and 280 (hospital pack) film-coated tablets.<\/p>\n\n\n\n
Not all pack sizes may be marketed.<\/p>\n\n\n\n
Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n
Marketing Authorisation Holder<\/strong><\/p>\n\n\n\nEvolan Pharma AB<\/p>\n\n\n\n
Box 120<\/p>\n\n\n\n
SE-182 12 Danderyd<\/p>\n\n\n\n
Manufacturer<\/strong><\/p>\n\n\n\nLICONSA LABORATORIES, SA<\/p>\n\n\n\n
Of. Miralcampo, No 7, Poigono industrial Miralcampo<\/p>\n\n\n\n
19200 Azuqueca de Henares (guadalajara)<\/p>\n\n\n\n
Spain<\/p>\n\n\n\n
This medicinal product is authorized under the European Economic Area under the names:<\/p>\n\n\n\n
50 mg \/ 12.5 mg<\/em><\/p>\n\n\n\nAustria: Losartan potassium Hydrochlorothiazide Liconsa 50 \/ 12.5 mg Film tablet<\/p>\n\n\n\n
Belgium: Co- Losartan Apotex 50 \/ 12.5 mg compressed pill \/ Film tablet \/ film-coated tablet<\/p>\n\n\n\n
Denmark: Losartan \/ Hydrochlorothiazide Medical Valley<\/p>\n\n\n\n
Hungary: Prelow Plus 50\/12., 5 mg Film Tablet<\/p>\n\n\n\n
Ireland: Lotanos Comp 50 mg \/ 12.5 mg film-coated tablet<\/p>\n\n\n\n
Italy: Losartan and Idroclorothiazide Germed 50 \/ 12.5 mg compressed with film<\/p>\n\n\n\n
Luxembourg: Co-\u00a0Losartan\u00a0Apotex 50 \/ 12.5 mg compressed pill<\/p>\n\n\n\n
100 mg \/ 25 mg<\/em><\/p>\n\n\n\nAustria: Losartan potassium Hydrochlorothiazide Liconsa 100\/25 mg Film tablet<\/p>\n\n\n\n
Belgium: Co- Losartan Apotex 100\/25 mg compressed pill \/ Film tablet \/ film-coated tablet<\/p>\n\n\n\n
Denmark: Losartan \/ Hydrochlorothiazide Medical Valley<\/p>\n\n\n\n
Hungary: Prelow Plus 100\/25 mg Film Tablet<\/p>\n\n\n\n
Ireland: Lotanos Comp 100 mg \/ 25 mg film-coated tablet<\/p>\n\n\n\n
Italy: Losartan and Idroclorothiazide Germed 100\/25 mg compressed with film<\/p>\n\n\n\n
Luxembourg: Co- Losartan Apotex 100\/25 mg compressed pill<\/p>\n\n\n\n
Sweden: Marozid 100 mg \/ 25 mg Film-coated tablet<\/p>\n","protected":false},"excerpt":{"rendered":"
Marozide is a combination of an angiotensin II receptor antagonist ( losartan ) and a diuretic ( hydrochlorothiazide ). Angiotensin -II is a substance that is produced in the body and that binds to receptors in the blood vessels and causes them to contract. This results in an increase in blood pressure . Losartan prevents the binding of angiotensin -II to these receptors , which causes the blood vessels to dilate, which in turn leads to lowered blood pressure .<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,15580],"tags":[3664,3666,4301,6501,6503,6504,16778,16781,7947,4300,6502,16779,16450,16780],"class_list":["post-17364","post","type-post","status-publish","format-standard","hentry","category-medicines","category-m","tag-hydrochlorothiazide","tag-hydrochlorothiazide-side-effects","tag-hydrochlorothiazide-tablet","tag-losartan-potassium","tag-losartan-potassium-side-effects","tag-losartan-potassium-tablet","tag-marozid","tag-marozid-tablet","tag-what-hydrochlorothiazide-is-used-for","tag-what-is-hydrochlorothiazide","tag-what-is-losartan-potassium","tag-what-is-marozid","tag-what-losartan-potassium-is-used-for","tag-what-marozid-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/17364","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=17364"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/17364\/revisions"}],"predecessor-version":[{"id":17393,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/17364\/revisions\/17393"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=17364"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=17364"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=17364"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}