Breast-feeding<\/em><\/p>\n\n\n\nTell your doctor if you are breastfeeding or planning to start breastfeeding.\u00a0Losartan \/ Hydrochlorothiazide Sandoz is not recommended for breastfeeding and your doctor may choose another treatment if you want to breastfeed your baby.<\/p>\n\n\n\n
Ask your doctor or pharmacist for advice before taking any medicine.<\/p>\n\n\n\n
Driving and using machines<\/h2>\n\n\n\n
When starting treatment with this medicine, you should not perform actions that may require sharpened attention (eg driving a motor vehicle or performing dangerous work) until you know how well you tolerate your medicine.<\/p>\n\n\n\n
You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects.\u00a0The description of these effects and side effects can be found in other sections.\u00a0Read all the information in this leaflet for guidance.\u00a0If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n
Losartan \/ Hydrochlorothiazide Sandoz contains sodium<\/h2>\n\n\n\n
This medicine contains less than 1 mmol (23 mg) sodium per tablet, ie essentially ‘sodium-free’.<\/p>\n\n\n\n
How to take Losartan \/ Hydrochlorothiazide Sandoz<\/h2>\n\n\n\n
Always take Losartan \/ Hydrochlorothiazide Sandoz exactly as your doctor or pharmacist has told you.\u00a0Ask your doctor or pharmacist if you are unsure.\u00a0Your doctor will decide on the appropriate\u00a0dose\u00a0of Losartan \/ Hydrochlorothiazide Sandoz, depending on your medical condition and whether you are taking other medicines.\u00a0You must continue to take Losartan \/ Hydrochlorothiazide Sandoz as\u00a0prescribed\u00a0by\u00a0your doctor\u00a0to maintain even control of your\u00a0blood pressure.<\/p>\n\n\n\n
Take the tablet with a glass of water. The tablet can be taken with or without food.<\/p>\n\n\n\n
Use for adults<\/em><\/strong><\/p>\n\n\n\nThe usual dose is 1 tablet daily.<\/p>\n\n\n\n
Use for the elderly<\/em><\/strong><\/p>\n\n\n\nDose adjustment is usually not necessary in the elderly.<\/p>\n\n\n\n
Use in patients with renal impairment and during hemodialysis<\/em><\/strong><\/p>\n\n\n\nIn the case of moderate renal impairment, no dose adjustment is usually required.\u00a0Do not use Losartan \/ Hydrochlorothiazide Sandoz if you have severe renal impairment.<\/p>\n\n\n\n
Losartan \/ Hydrochlorothiazide Sandoz is not recommended for patients receiving\u00a0hemodialysis.<\/p>\n\n\n\n
Use in patients with hepatic impairment<\/em><\/strong><\/p>\n\n\n\nLosartan \/ Hydrochlorothiazide Sandoz should be used with caution in patients who have had mild to moderate hepatic impairment. Do not use Losartan \/ Hydrochlorothiazide Sandoz if you have severe hepatic impairment (see section 2. \u201cDo not take Losartan \/ Hydrochlorothiazide Sandoz\u201d).<\/p>\n\n\n\n
Use for children and adolescents<\/em><\/strong><\/p>\n\n\n\nLosartan \/ Hydrochlorothiazide Sandoz should not be given to children and adolescents under 18 years of age.<\/p>\n\n\n\n
Use for black patients<\/em><\/strong><\/p>\n\n\n\nDose adjustment may be required as Losartan \/ Hydrochlorothiazide Sandoz may be less effective in black patients than in non-black patients.<\/strong><\/p>\n\n\n\nPossible side effects<\/h2>\n\n\n\n
Like all medicines, this medicine can cause\u00a0side effects, although not everybody gets them.<\/p>\n\n\n\n
If you experience any of the following, stop taking Losartan \/ Hydrochlorothiazide Sandoz and talk to your doctor immediately or go to the nearest emergency department:<\/strong><\/p>\n\n\n\nA severe\u00a0allergic reaction\u00a0(rash,\u00a0itching, swelling of the face, lips, mouth, or throat, which may cause difficulty swallowing or breathing).<\/p>\n\n\n\n
This is a serious but rare\u00a0side effect\u00a0that occurs in more than 1 patient in 10,000 but less than 1 patient in 1,000. You may need\u00a0emergency\u00a0medical care or hospitalization.<\/p>\n\n\n\n
The following side effects have been reported:<\/p>\n\n\n\n
Common<\/strong> (may affect up to 1 in 10 people):<\/p>\n\n\n\n- coughing, infection of the upper airways, nasal congestion, sinusitis, sinus disorder<\/li>
- diarrhea, stomach pain, nausea, indigestion<\/li>
- muscle aches or cramps, pain in the legs or back<\/li>
- insomnia, headache, dizziness<\/li>
- weakness, fatigue, chest pain<\/li>
- increased potassium levels (which may cause abnormal heart rhythm), decreased hemoglobin levels<\/li>
- changes in renal function, including renal failure<\/li>
- too low blood sugar ( hypoglycaemia ).<\/li><\/ul>\n\n\n\n
Uncommon<\/strong> (may affect up to 1 in 100 people):<\/p>\n\n\n\n- anemia , red or brownish spots on the skin (sometimes especially on feet, legs, arms and buttocks, with joint pain, swelling of hands and feet and stomach pain), bruising, decreased number of white blood cells , coagulation problems, decreased number of platelets<\/li>
- loss of appetite, high uric acid levels in the blood or gout , high blood sugar levels, abnormal salt balance in the blood<\/li>
- anxiety, nervousness, panic disorder (recurring panic attacks), confusion, depression, deviant dreams, sleep disturbance, drowsiness, memory loss<\/li>
- numbness and tingling or similar sensations, pain in arms and legs, tremors, migraines , fainting<\/li>
- blurred vision, burning sensation or tingling in the eyes, conjunctivitis of the eye, impaired visual acuity , yellowing<\/li>
- ringing, buzzing, howling or clicking in the ears, dizziness<\/li>
- low blood pressure , which can be caused by changes in posture (you feel dizzy or weak when standing up), angina (chest pain), abnormal heart rate , cardiovascular event ( TIA , “ministroke”), heart attack, palpitations<\/li>
- inflammation of the blood vessels, which is often associated with skin rashes or bruising<\/li>
- sore throat, shortness of breath, bronchitis , pneumonia , water in the lungs (causing shortness of breath), nosebleeds, runny nose, nasal congestion<\/li>
- constipation, difficult-to-treat constipation, gas, upset stomach, stomach cramps, vomiting, dry mouth , inflammation of the salivary glands, toothache<\/li>
- jaundice (yellow eyes and yellow skin), pancreatitis<\/li>
- hives, itching , inflammation of the skin, rash, redness of the skin, photosensitivity, Lyell’s syndrome (skin that looks like it has been burnt and flaky), dry skin, flushing (heat sensation, redness of the skin), sweating, hair loss<\/li>
- pain in arms, shoulders, hips, knees or other joints, joint swelling, stiffness, muscle weakness<\/li>
- urinary incontinence (even at night), abnormal kidney function including kidney inflammation, urinary tract infection, sugar in the urine<\/li>
- decreased sexual desire, impotence<\/li>
- facial swelling, local swelling ( edema ), fever.<\/li><\/ul>\n\n\n\n
Rare<\/strong> (may affect up to 1 in 1,000 people):<\/p>\n\n\n\n- hepatitis ( inflammation of the liver), abnormal liver function values.<\/li><\/ul>\n\n\n\n
Has been reported<\/strong>\u00a0(occurs in the unknown number of users):<\/p>\n\n\n\n- flu-like symptoms<\/li>
- unexplained muscle pain with dark (tea-colored) urine ( rhabdomyolysis )<\/li>
- low levels of sodium in the blood ( hyponatremia )<\/li>
- general malaise<\/li>
- taste disorders ( dysgeusia )<\/li>
- skin and lip cancer (non- melanoma skin cancer)<\/li>
- nearsightedness<\/li>
- impaired vision or pain in the eyes due to high pressure (possible signs of fluid accumulation in the eye (between the choroid and retina) or acute narrow-angle glaucoma ).<\/li><\/ul>\n\n\n\n
How to store Losartan \/ Hydrochlorothiazide Sandoz<\/h2>\n\n\n\n
Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n
Do not use this medicine after the expiry date which is stated on the carton\/jar\/blister after EXP.\u00a0The expiration date is the last day of the specified month.<\/p>\n\n\n\n
Blister: Do not store above 25 \u00b0 C. Store in the original package. HDPE can: Do not store above 25 \u00b0 C. Store in the original package. Close the jar tightly. Moisture sensitive.<\/p>\n\n\n\n
Shelf life of the medicine after opening:<\/p>\n\n\n\n
Jar: 6 months<\/p>\n\n\n\n
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.<\/p>\n\n\n\n
Contents of the pack and other information<\/h2>\n\n\n\nContent declaration<\/h2>\n\n\n\n
The\u00a0active substances<\/strong>\u00a0are losartan potassium and\u00a0hydrochlorothiazide.<\/p>\n\n\n\nOne film-coated tablet contains 100 mg losartan potassium and 12.5 mg hydrochlorothiazide .<\/p>\n\n\n\n
Other ingredients<\/em><\/strong> are:<\/p>\n\n\n\nTablet core: microcrystalline cellulose with silica, croscarmellose sodium, silica, colloidal anhydrous silica, magnesium stearate.<\/p>\n\n\n\n
Film coating: hypromellose, hydroxypropyl cellulose, titanium dioxide (E171).<\/p>\n\n\n\n
What the medicine looks like and contents of the pack<\/h2>\n\n\n\n
Losartan \/ Hydrochlorothiazide Sandoz are white, round, biconvex, film-coated tablets marked with 100 and 12.5 on one side.<\/p>\n\n\n\n
The film-coated tablets are packaged in OPA \/ Alu \/ PVC \/ Alu-blister or ACLAR \/ PVC \/ Alu-blister and stored in a carton or packed in HDPE jars with PP screw caps.\u00a0The HDPE can contain silica gel as a desiccant (to absorb moisture) either in the plastic screw cap or in a capsule\/bag.\u00a0Do not swallow the capsule\/bag with silica gel.<\/p>\n\n\n\n
Blisters: 7, 14, 20, 28, 30, 50, 56, 60, 84, 90, 98 and 100 film-coated tablets<\/p>\n\n\n\n
Jar: 100 and 250 film-coated tablets<\/p>\n\n\n\n
Not all pack sizes may be marketed.<\/p>\n\n\n\n
Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n
Marketing Authorisation Holder<\/strong><\/p>\n\n\n\nSandoz A \/ S, Edvard Thomsens Vej 14, 2300 Copenhagen S, Denmark<\/p>\n\n\n\n
Manufacturer<\/strong><\/p>\n\n\n\nLek Pharmaceuticals dd Verovskova 57, SI-1526 Ljubljana, Slovenia<\/p>\n\n\n\n
or<\/p>\n\n\n\n
Lek SA, Ul. Domaniewska 50 C, 02-672 Warsaw, Poland<\/p>\n\n\n\n
or<\/p>\n\n\n\n
Lek SA, Ul. Podlipie 16 C, 95010 Strykow, Poland<\/p>\n\n\n\n
or<\/p>\n\n\n\n
Salutas Pharma GmbH, Otto von Guericke Allee 1, 39179 Barleben, Germany<\/p>\n\n\n\n
or<\/p>\n\n\n\n
Lek Pharmaceuticals dd, Trimline 2 D, 9220 Lendava, Slovenia<\/p>\n","protected":false},"excerpt":{"rendered":"
Losartan potassium belongs to a group of medicines called angiotensin II receptor antagonists. These allow the blood vessels to relax, which in turn lowers blood pressure .<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2200,15579],"tags":[12407,16443,16446,16449,12409,12408,16444,16447,16448,16445],"class_list":["post-17103","post","type-post","status-publish","format-standard","hentry","category-medicines","category-l","tag-hydrochlorothiazide-sandoz","tag-losartan","tag-losartan-hydrochlorothiazide-sandoz-losartan-potassium-hydrochlorothiazide","tag-losartan-hydrochlorothiazide-sandoz-losartan-potassium-hydrochlorothiazide-side-effects","tag-what-hydrochlorothiazide-sandoz-is-used-for","tag-what-is-hydrochlorothiazide-sandoz","tag-what-is-losartan","tag-what-is-losartan-hydrochlorothiazide-sandoz-losartan-potassium-hydrochlorothiazide","tag-what-losartan-hydrochlorothiazide-sandoz-losartan-potassium-hydrochlorothiazide-is-used-for","tag-what-losartan-is-used-for"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/17103","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=17103"}],"version-history":[{"count":6,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/17103\/revisions"}],"predecessor-version":[{"id":17139,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/17103\/revisions\/17139"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=17103"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=17103"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=17103"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}